BUSCADOR RECOLECTA

This dataset is part of the project "Voices of Spanish Poets: Vocal Archive and Experimental Study on Poetry Reading" (VSP), WP3, Funded by the European Union. Views and opinions expressed are however those of the authors only and do not necessarily reflect those of the European Union or the European Research Executive Agency (REA). Neither the European Union nor the granting authority can be held responsible for them., Corpus of 84 audio stimuli corresponding to three different reading styles of 28 enjambments by Federico García Lorca. The audio dataset was used in an experimental study involving eye-tracking. Readings and recordings by Miguel Rodríguez Monteavaro. This dataset and study is part of the project "Voices of Spanish Poets: Vocal Archive and Experimental Study on Poetry Reading" (VSP), WP3., European Union

Data underlying the wildlife population abundances shown in Figure 4. Population sizes (kilometric abundance index) were estimated monthly as the number of observed individuals along fixed, 20-m width transects adding up to 10.2 km length and distributed throughout the estate, from 2006 to 2018.

Growing up in a high family risk (HFR) environment is accompanied by difficulties in executive functions (EFs) and interpersonal skills (IS) that may persist into adulthood. Because preadolescence is a critical period, this study will assess a multicomponent mediational intervention program, to determine the possibility of improving these skills. There were 61 preadolescent participants, between the ages of 8 and 12; 34 were associated with HFR and 27 were associated with low family risk (LFR). All the participants were tested with EF and IS measures. Results showed that, prior to treatment, the HFR preadolescents had poorer performance on EF and IS than did the LFR preadolescents. In the posttreatment measures, to assess the utility of the multicomponent program, the HFR preadolescents group was able to match the scores of those in the LFR group. In addition, intervention effects in the HFR group were maintained in the follow-up assessment., Proyecto de Excelencia 2012 con referencia P12-SEJ-560 de la Junta de Andalucía

Inhibition of SARS-CoV-2 membrane fusion is a highly desired target to combat COVID-19. The interaction between the spike's heptad repeat (HR) regions 1 (HR1) and 2 (HR2) is a crucial step during the fusion process and these highly conserved HR regions constitute attractive targets for fusion inhibitors. However, the relative importance of each subregion of the long HR1-HR2 interface for viral inhibition remains unclear. Here, we designed, produced, and characterized a series of chimeric miniproteins that mimic two different half subdomains of HR1. The proteins were designed as single polypeptide chains that spontaneously fold into antiparallel trimeric helical bundles aimed at structurally imitate the molecular surface of each HR1 half subregion. All the miniproteins folded stably as helical structures and could bind complementary HR2 peptides with moderate affinity. However, only the miniproteins mimicking the N-terminal HR1 half subdomain, but not those imitating C-terminal one, could inhibit cell infection by SARS-COV-2 real viruses in cell cultures. Most interestingly, the inhibitory activity of the miniproteins correlated with their structural stability, but not with their relative binding affinity for HR2 peptides. These results are highly relevant for designing more focused and active fusion inhibitors targeting the highly conserved HR2 region of the Spike., Departamento de Química Física, Facultad de Ciencias, Universidad de Granada. Grupo FQM-171

Grupo SEJ-625. Dpto. Comercialización e Investigación de Mercados.