BUSCADOR RECOLECTA

The ability of amphiphilic Phthalocyanine (Pc) photosensitizers (PS) (Zn(II)Pcs PS1, PS2, and PS3) to assemble into cationic nanoparticles in water and to photo-inactivate bacterial strains is demonstrated. All the synthesized Zn(II)Pcs exhibit an AABB functionalization pattern, having a binaphthyloxy-linked bisisoindole (AA) functionalized at the chiral binaphthol core with branched (PS1) or linear (PS2 and PS3) poly-ammonium chains, and two non-functionalized isoindole rings (BB). The aggregation behavior and the stability of the nanoparticles formed by the three PS in water is studied by UV–vis, fluorescence and circular dichroism (CD) spectroscopies, and their shape and size is determined by transmission electron microscopy (TEM) and dynamic light scattering (DLS). The PS nanoparticles prove efficient in the photoinactivation of S. aureus and E. coli. Although PS2 and PS3 present better photophysical features in their monomeric form (i.e., improved singlet oxygen quantum yield), PS1 is more effective in killing both types of strains, especially the gram-negative E. coli. This observation may derive from the low stability found for PS1 nanoparticles, which easily disassemble after binding to the bacteria surface, recovering the photophysical properties of the non-aggregated species.

Structural and photophysical characterization of compounds (Raw data).

The project, 'DIGITENDER: Extracción terminológica automática y corpora de dominios específicos para la visibilización de los problemas de salud relacionados con la mujer,' aims to develop an automatic term extractor focused on endometriosis and menopause to enhance the visibility of women's health issues that are often overlooked. To achieve this, a language model is trained using annotated terms within their context. This publication contains the annotation guidelines. This is the annotation guidelines document created for the DIGITENDER project. It provides a set of instructions to standardize the criteria used by linguists during the annotation process. In this case, the annotation focuses on terms related to women's health, specifically endometriosis and menopause. The document includes brief theoretical insights as well as numerous rules, cases, and examples.

El proyecto "DIGITENDER: Extracción terminológica automática y corpora de dominios específicos para la visibilización de los problemas de salud relacionados con la mujer" tiene como objetivo principal crear un extractor automático de términos en los ámbitos de la endometriosis y la menopausia con el fin de visibilizar problemas de salud de la mujer habitualmente invisibilizados. Con este fin, se entrena un modelo de lenguaje con anotaciones previstas de términos en su contexto. Esta publicación se trata del la guía de anotación. Se trata de la guía de anotación que se ha creado para el proyecto DIGITENDER. Contiene una serie de indicaciones para que unificar los criterios de los lingüistas a la hora de anotar. En este caso, la anotación es de términos relacionados con la salud de la mujer: endometriosis y menopausia. Se ofrecen unas ligeras nociones teóricas y numerosas reglas, casos y ejemplos.