Resultados totales (Incluyendo duplicados): 35619
Encontrada(s) 3562 página(s)
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352915
Dataset. 2023

SUPPLEMENTARY MATERIAL: AVOCADO SEED BY-PRODUCT USES IN EMULSION-TYPE INGREDIENTS WITH NUTRACEUTICAL VALUE: STABILITY, CYTOTOXICITY, NUTRACEUTICAL PROPERTIES, AND ASSESSMENT OF IN VITRO ORAL-GASTRIC DIGESTION

  • Sánchez-Quezada, Vanessa
  • Gaytán-Martínez, Marcela
  • Recio, Isidra
  • Loarca-Piña, Guadalupe
Reagents were acquired from J.T. Baker [borate (G23644), calcium chloride (0970-01), methanol (34,860/2L), Monopotassium phosphate (3246-01), magnesium chloride (2448-01),Sodium bicarbonate (JTB-3506-01), trichloroacetic acid (0414-01), potassium chloride (3040-01), potassium phosphate (3246-01)], Sigma-Aldrich [( +)-catechin (C1251-10 g), gallic acid (G7384-100 g), hydrochloric acid (C3878), 2,2-diphenyl-1-picrylhydrazyl (DPPH*; 257,621–100mg), ethanol (459,836/2L), Folin-Ciocalteu reagent (F9252-1L), lipase (L0777-50mL), linolenic acid (62240-25mL), magnesium chloride (M2670), nitroprusside sodium (71778-25g), thiobarbituric acid (T-5500), sodium chloride (S753), rutin (R5143), pepsin (P7000-100g), and Hycel [casein (55,695), α-amylase (10U/mg), β-carotene (C4582-10mg)], Meyer [Carbonate ammonium (8000-73-5), Hexane (V1020647), potassium iodide (J1220812), ferrous sulfate (7782-63-0)]., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/352915
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352915
HANDLE: http://hdl.handle.net/10261/352915
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352915
PMID: http://hdl.handle.net/10261/352915
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352915
Ver en: http://hdl.handle.net/10261/352915
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352915

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352916
Dataset. 2023

SJ-DOCX-1-WSO-10.1177_17474930231180451 – SUPPLEMENTAL MATERIAL FOR REPERFUSION BY ENDOVASCULAR THROMBECTOMY AND EARLY CEREBRAL EDEMA IN ANTERIOR CIRCULATION STROKE: RESULTS FROM THE SITS-INTERNATIONAL STROKE THROMBECTOMY REGISTRY

  • Magnus Thorén
  • Escudero-Martínez, Irene
  • Andersson, Tomas
  • Chen, Shih-Yin
  • Tsao, Nicole
  • Khurana, Dheeraj
  • Beretta, Simone
  • Peeters, Andre
  • Tsivgoulis, Georgios
  • Roffe, Christine
  • Ahmed, Niaz
List of supplemental tables: Table I. Univariable risks for moderate or severe CED, by individual characteristics.-- Table II. Final models for CED levels (reference: no CED) with reperfusion classified into successful versus unsuccessful.-- Table III. Detailed data for the demonstration of effect modification by potential indicators of large infarct, using the final adjusted model., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/352916
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352916
HANDLE: http://hdl.handle.net/10261/352916
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352916
PMID: http://hdl.handle.net/10261/352916
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352916
Ver en: http://hdl.handle.net/10261/352916
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352916

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352921
Dataset. 2024

DATA FOR PROBING THE TUNABILITY OF MAGNETISM WITH EXTERNAL PRESSURE IN METASTABLE SR2NIIRO6 DOUBLE PEROVSKITE

  • Laguna-Marco, M. A.
  • Arias-Egido, Eduardo
  • Cuartero, Vera
  • Herrero-Albillos, Julia
  • Fabbris, Gilberto
  • Proyecto: PID2020-115159GB-I00
High pressure x-ray diffraction (HP-XRD) measurements were carried out at the 16-BM-D beamline of the Advanced Photon Source (APS), Argonne National Laboratory (ANL). HP-XRD data were recorded at T = 10 K and under pressures up to 50 GPa. Fine powder was loaded into the sample chamber (~90-µm hole in a Re gasket preindented to 30 µm) together with He gas as the quasihydrostatic pressure medium and a couple of ruby spheres and gold grains as the in situ pressure calibrants. A symmetric diamond anvil cell (DAC, Princeton) with 300-µm culet anvils was used for these measurements. Data were collected using x-ray radiation with lambda = 0.4016 Å (30.87 keV) and a MAR345 image plate. The two-dimensional diffractograms were integrated using the DIOPTAS software The long-range XAS spectra (EXAFS) at the Ir L3 absorption edge were recorded under applied high pressures (2.5–50 GPa) and at low temperature (10 K) at the ID24 beamline of the ESRF (Grenoble, France). ID24 energy dispersive spectrometer was used to perform the EXAFS measurements. The measurements were also performed in transmission by using a one-dimensional Hamamatsu CCD camera. We used nanopolycrystalline diamond anvils to avoid glitches (i.e.,strong Bragg peaks) from the anvils on the EXAFS spectra. Ruby chips were used as pressure markers and Ne gas was used as pressure transmitting medium. The short-range XAS (XANES) and XMCD measurements under high pressurewere carried out at beamline 4-ID-D of the Advanced PhotonSource, Argonne National Laboratory. The spectra were recorded at the Ir L2,3 absorption edges to probe the Ir 5d states. Circularly polarized x rays were generated using phase-retarding optics. Harmonic rejection was achieved by the combined effects of x-ray reflection from two Pd mirrors at 3.1 mrad incidence angle and detuning of the second crystal in the Si(111) double crystal monochromator. XMCD was measured by switching x-ray helicity (13.1 Hz) and detecting the related modulation in absorption coefficient with a lock-in amplifier. All the measurements were done in transmission geometry. For the high pressure measurements the powdered samples were loaded on copper-beryllium DACs fitted with 300-µm culet anvils and a Re gasket. Ne gas was used as the quasihydrostatic pressure transmitting medium. The samples were cooled in 4He vapor using the variable temperature insert of the superconducting magnet, and pressure was controlled remotely using a He-gas membrane., Spanish MICINN Projects No. PID2020-115159GBI00/AEI/10.13039/501100011033, MAT2017-83468-R (AEI/FEDER, UE) and MAT2017-84496-R (AEI/FEDER, UE; Regional Government of Aragon (Grant No. E12-20R RASMIA), Fig1a_Ir_L3edge_XMCD_vs_HP_SNIO.dat Fig1b_Ir_L2edge_XMCD_vs_HP_SNIO.dat Fig1c_Ir_L3edge_XMCD_vs_HP_SZIO.dat Fig2a_Ir_L3edge_XAS_vs_HP_SNIO.dat Fig2a_Ir_L2edge_XAS_vs_HP_SNIO.dat Fig2b_Ir_L3edge_XAS_vs_HP_SZIO.dat Fig3_XRD_vs_HP_SNIO.dat FigIr_L3edge_EXAFS_vs_HP_SNIO.dat, Peer reviewed

DOI: http://hdl.handle.net/10261/352921, https://doi.org/10.20350/digitalCSIC/16197
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352921
HANDLE: http://hdl.handle.net/10261/352921, https://doi.org/10.20350/digitalCSIC/16197
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352921
PMID: http://hdl.handle.net/10261/352921, https://doi.org/10.20350/digitalCSIC/16197
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352921
Ver en: http://hdl.handle.net/10261/352921, https://doi.org/10.20350/digitalCSIC/16197
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352921

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353007
Dataset. 2023

SUPPLEMENTAL MATERIAL: EXPRESSION AND FUNCTION OF CAENORHABDITIS ELEGANS UNCP-18, A PARALOG OF THE SM PROTEIN UNC-18

  • Boeglin, Marion
  • Leyva-Díaz, Eduardo
  • Hobert, Oliver
Supplementary Movie S1 Legend: Progeny of unc-18(e81); uncp-18(syb6377)/+ animals. Eggs laid by unc-18(e81); uncp-18(syb6377)/+ animals were transferred from a plate onto the agar pad on a microscope slide with M9 butter, covered with a glass coverslip, sealed with Vaseline and imaged every 5 minutes for around 13 hours using a Zeiss Imager Z2 microscope with 63x objective. Note that the embryo on the top right does not pass through embryonic development as all other embryos do., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/353007
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353007
HANDLE: http://hdl.handle.net/10261/353007
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353007
PMID: http://hdl.handle.net/10261/353007
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353007
Ver en: http://hdl.handle.net/10261/353007
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353007

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353068
Dataset. 2024

VEGETATION INDICES FOR THE IBERIAN PENINSULA AND BALEARIC ISLANDS (VIIB) DATABASE

ÍNDICES DE VEGETACIÓN PARA LA PENÍNSULA IBÉRICA Y LAS ISLAS BALEARES (VIIB)

  • Franquesa, Magí
  • Reig-Gracia, Fergus
  • Vicente Serrano, Sergio M.
[EN] It contains 4 files, one for each vegetation index—NDVI, kNDVI, SNDVI, and SkNDVI—in netcdf format. Multiple options exist for reading and manipulating netCDF files (.nc), with the most common including GIS applications like QGIS and ArcMap, specialized applications such as Panoply (https://www.giss.nasa.gov/tools/panoply/), and dedicated libraries such as ncdf4, raster, or terra in R, as well as netCDF4 or xarray in Python, among others. [ES] Contiene 4 ficheros, uno por cada índice de vegetación—NDVI, kNDVI, SNDVI y SkNDVI—, en formato netcdf. Existen multiples opciones para leer y manipular ficheros NetCDF (.nc), entre las más habituales encontramos aplicaciones de SIG como Qgis o ArcMap, aplicaciones específicas como Panoply (https://www.giss.nasa.gov/tools/panoply/), o mediante librerías específicas como ncdf4, raster o terra en R o netCDF4 o xarray en Python, entre otras., [EN] The Vegetation Indices for the Iberian Peninsula and Balearic Islands (VIIB) Database offers comprehensive long-term time series of vegetation indices—NDVI, kNDVI, SNDVI, and SkNDVI—with a bi-weekly temporal resolution and a spatial resolution of 1.1 km, spanning from 1981 to the present day. Specially designed to encompass the Iberian Peninsula and Balearic Islands, this database facilitates the exploration of both historical and contemporary vegetation patterns and anomalies throughout the region over more than forty years. With bi-weekly updates, it provides a continuous and up-to-date resource for understanding vegetation changes and trends. The database integrates NDVI datasets— Sp_1km_NDVI, MYD13A2 and VNP13A2—derived from AVHRR, MODIS and VIIRS satellite sensors, respectively. These NDVI products have undergone a rigorous harmonization process, ensuring the temporal consistency of the time-series., [ES] La Base de Datos de Índices de Vegetación para la Península Ibérica y las Islas Baleares (VIIB) proporciona series temporal extensas y detalladas de índices de vegetación—NDVI, kNDVI, SNDVI y SkNDVI— con una resolución temporal quincenal y una resolución espacial de 1.1 km, cubriendo el periodo desde 1981 hasta la actualidad. Específicamente diseñada para la Península Ibérica y las Islas Baleares, esta base de datos permite la exploración de patrones de vegetación tanto históricos como actuales, así como la detección y estudio de anomalías a lo largo de la región durante más de cuatro décadas. Con actualizaciones quincenales, proporciona un recurso continuo y actualizado para comprender los cambios y tendencias en la vegetación. La base de datos integra conjuntos de datos de NDVI—Sp_1km_NDVI, MYD13A2 y VNP13A2—derivados de los sensores satelitales AVHRR, MODIS y VIIRS, respectivamente. Estos productos NDVI han sido sometidos a un proceso de armonización riguroso, asegurando la consistencia temporal de las series temporales., Ayuda JDC2022-048710-I financiada por MCIN/AEI /10.13039/501100011033 y por la Unión Europea NextGenerationEU/PRTR. Grant JDC2022-048710-I funded by MCIN/AEI/ 10.13039/501100011033 and by the European Union NextGenerationEU/PRTR., ndvi.nc kndvi.nc sndvi.nc skndvi.nc, No

DOI: http://hdl.handle.net/10261/353068, https://doi.org/10.20350/digitalCSIC/16201, https://doi.org/10.20350/digitalCSIC/16200
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353068
HANDLE: http://hdl.handle.net/10261/353068, https://doi.org/10.20350/digitalCSIC/16201, https://doi.org/10.20350/digitalCSIC/16200
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353068
PMID: http://hdl.handle.net/10261/353068, https://doi.org/10.20350/digitalCSIC/16201, https://doi.org/10.20350/digitalCSIC/16200
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353068
Ver en: http://hdl.handle.net/10261/353068, https://doi.org/10.20350/digitalCSIC/16201, https://doi.org/10.20350/digitalCSIC/16200
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353068

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353144
Dataset. 2023

DESCRIPTION OF FOUR NEW SALINIBACTER SPECIES, TWO CULTIVATED AND NAMED FOLLOWING THE RULES OF THE BACTERIOLOGICAL CODE: SALINIBACTER PEPAE SP. NOV., SALINIBACTER GRASSMERENSIS SP. NOV.; AND TWO UNCULTIVATED AND NAMED FOLLOWING THE RULES OF THE SEQCODE: SALINIBACTER ABYSSI SP. NOV., AND SALINIBACTER PAMPAE SP. NOV. [DATASET]

  • Viver, Tomeu
  • Conrad, Roth E.
  • Lucio, Marianna
  • Harir, Mourad
  • Urdiain, Mercedes
  • Gago, Juan F.
  • Suárez-Suárez, Ana
  • Bustos, Esteban
  • Sánchez-Martínez, Rodrigo
  • Mayol, Eva
  • Fassetta, Federico
  • Pang, Jinfeng
  • Mădălin Gridan, Ionuț
  • Venter, Stephanus N.
  • Santos, Fernando
  • Baxter, Bonnie
  • Llames, María E.
  • Cristea, Adorján
  • Banciu, Horia L.
  • Hedlund, Brian P.
  • Stott, Matthew B.
  • Kämpfer, Peter
  • Amann, Rudolf
  • Schmitt-Kopplin, Philippe
  • Konstantinidis, Konstantinos T.
  • Rosselló-Mora, Ramón
Figure S1. Geographical distribution of the six locations studied here and their inter-location distances (given in the table). The distances given in each location refer to Mallorca. The hypersaline here are: Mallorca (Es Trenc and S’Avall and separated by 3.5 km) and Santa Pola in Spain, Fără Fund in Romania, Great Salt Lake (USA), Pampa (Laguna Colorada Chica and Laguna Colorada Grande, separated by 23 Km), and Lake Grassmere (New Zealand). Table S1. Statistics of Salinibacter MAGs recovered using different bioinformatic tools. MAGs selected for further analysis and taxonomic classification are marked in red. Text S1: In addition to the taxonomic study, here we assessed the different tools SPADES and MegaHIT assemblers, and MetaBAT binning tools selecting contigs with length > 2,000 pbs or > 5,000 pbs to retrieve the best quality MAG (Sup. Table S1). We observed that different tools and combinations rendered different qualities of the MAGs. The selection of contigs with length > 5,000 pbs binning rendered MAGs with a lower genome size, lower completeness and similar contamination. From the FF metagenome (Romania), the highest quality MAG was retrieved using the assembler SPADES and MetaBAT binning tool using a minimum contig length of 2,000 pbs. From CCH and CG metagenomes (Argentina), the highest quality MAGs were retrieved using the assembler MegaHIT and MetaBAT binning tool using a minimum contig length of 2,000 pbs (Sup. Table S1). Figure S2. Genomic clustering based on Average Amino-acid Identity (AAI) of genomes included in the study. Figure S3. Pangenome hierarchical clustering based on the presence (grey) or absence (black) of orthologous genes. Table S2. Pangenome statistics between genomes belonging to the same species. Table S3: CRISPR-Cas systems found in the Salinibacter pepae and Salinibacter grassmerensis genomes. Table S4. Cell morphologies of the new isolates. All cells have been cultivated onto MA agar. for 10 days at 12ºC. The morphology was observed under an optical Microsope (Zeiss Axio Imager 100X). Photomicrograph showing cells of strain observed by oil-immersion differential interference contrast (DIC) microscopy (Nomarski). Figure S4. Hierarchical clustering of all cellular and supernatant metabolomes analyzed with electrospray-negative mode ICR-FT/MS (upper panel). Loading plots in where single molecules are colored based on the specific classes that they belong to: Grey: Core Metabolome. Yellow: discriminative for Sal. ruber. Red: discriminative for Sal. pepae. Orange: discriminative for Sal. altiplanensis (middle panel). Core metabolomes of the genus (lower panel). (A) water-soluble (left figures) and (B) water-insoluble (but methanol soluble; right figures) fractions. Figure S5. Count of saturated, mono-, di-, tri-, tetra-, and more unsaturated fatty acids classified as core metabolites in water-soluble (orange color) and water-insoluble (blue color) fractions versus their degree of unsaturation. Insert Venn diagram show count of unique and common fatty acids in each case. Figure S6. Count of discriminating fatty acids classified as saturated, mono-, di-, tri-, tetra-, and more unsaturated compounds in Sal. pepae, Sal. ruber and Sal. altiplanensis according to their degree of unsaturation in the water-soluble fractions or in the water-insoluble fractions. Figure S7. Van Krevelen plots showing shared compounds assigned in Sal. grassmerensis NZ140T with the discriminating molecular compositions of Sal. ruber, Sal. pepae and Sal. altiplanensis when comparing sample pairs (see also Figure 5B, 5C and 5D). Here we looked at the molecular compositions assigned in the case of Sal. grassmerensis NZ140T and checked whether they are present in the discriminating molecular compositions of Sal. ruber, Sal. pepae and Sal. altiplanensis. Insert histograms represent the molecular series based on CHO (blue), CHOS (green), CHNO (orange), and CHNOS (red) atom combinations. Insert percentages represent the numbers (in %) of shared molecular compositions of Sal. grassmerensis NZ140T with respect to the total discriminant compounds of Sal. ruber, Sal. pepae as well as Sal. altiplanensis (see also Figure 5B, 5C and 5D). Text S2: From the Laguna Colorada Chica, we detected 38 contigs encoding for a 16S rRNA gene and 3 affiliated with the Salinibacteraceae family (Sup. Figure S6). We identified one almost complete 16S rRNA sequence (1,555 bp) in a contig with a sequencing depth of 77.3X, and 2 partial sequences (< 945 bp) showing a sequencing depth < 12.7X. The largest 16S rRNA gene sequence with the highest coverage affiliated with the Salinibacter genus with an identity of 97.3% with Sal. pepae ESAV49Ts, 96.9% with Sal. ruber M31T, 96.3% with Sal. altiplanensis AN15T, 96% with Sal. grassmerensis NZ140T and 96.2% with Sal. abyssi ROFFTs, respectively (Sup. Figure S6 and Sup. Spreadsheet S2). The shorter assembled 16S rRNA sequences showed a percentage of similarity with any of the Salinibacter sequences < 95.4% (Sup. Figure S6). ARCCHTs represented the most abundant Salinibacter population in the metagenome of origin (with 1.9% relative abundance and 56X coverage), we confidently assigned the contig encoding the largest Salinibacter 16S rRNA gene to ARCCHTs. The sequence was deposited under the accession number GCA_947077715Ts. Supporting the assignation, from the Laguna Colorada Grande we detected 28 contigs encoding a 16S rRNA gene, 3 affiliated with the Salinibacteraceae family. The single complete 16S rRNA gene sequence (accession number GCA_947077705) showed 100% identity with the one assigned to ARCCHTs (Sup. Figure S3). In agreement, ARCG coverage 12X and the 16S rRNA encoding contig 17X. The agreement between the coverages and both affiliations based on 16S rRNA gene sequence reconstruction (Figure 1A) and the core-genome reconstruction (Figure 1B) confidently assigned the 16S rRNA genes to their respective MAGs in the samples of origin. Figure S8. Phylogenetic reconstruction based on the 16S rRNA gene sequence analysis of all Salinibacter species available in the LTP_01_2022, the MAGs recovered from metagenomes and the Salinibacteraceae 16S rRNA sequences recovered from assembled metagenomes from Colorada Chica (CCH) and Colorada Grande (CG), both located in Argentina. The tree was reconstructed using the maximum likelihood algorithm and is the result of the consensus of different approaches using distinct filters and datasets. The multifurcations indicate a branching order that could not be resolved. Bar indicates 10% sequence divergence. In brackets the accession number of each sequence is given. Table S5. MAGs metabolic reconstruction based on KEGG database annotations., 1-s2.0-S0723202023000255-mmc2.docx.-- 1-s2.0-S0723202023000255-mmc1.xlsx, Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/353144
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353144
HANDLE: http://hdl.handle.net/10261/353144
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353144
PMID: http://hdl.handle.net/10261/353144
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353144
Ver en: http://hdl.handle.net/10261/353144
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353144

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353153
Dataset. 2023

SUPPLEMENTARY INFORMATION: NEURONAL PROGENITORS OF THE DENTATE GYRUS EXPRESS THE SARS-COV-2 CELL RECEPTOR DURING MIGRATION IN THE DEVELOPING HUMAN HIPPOCAMPUS

  • Hernández-López, José Manuel
  • Hernández-Medina, Cristina
  • Medina-Corvalan, Cristina
  • Ródenas, Mónica
  • Almagro-García, Francisca
  • Pérez-García, Claudia
  • Echevarría, Diego
  • Carratalá-Marco, Francisco
  • Geijo-Barrientos, Emilio
  • Martínez, Salvador
Supplementary Figure 1: Control of immunolabelling and ACE2 expression in adult hippocampus. A-C) Pictures of the hippocampus fimbrial angle in control processed sections without primary ant-ACE2 antibodies: A) rabbit polyclonal anti-ACE2 (Abcam Cat# ab15348). Control sections processed with rabbit polyclonal anti-ACE2 (Sigma-Aldrich Cat#HPA000288) and mouse monoclonal anti-ACE2 (R&D Systems Cat# MAB933) were similar to this one (data not shown). B) rat monoclonal anti-GFAP (Millipore Cat# 345860-100UG). Control sections processed with goat polyclonal anti-Doublecortin (Santa Cruz Biotechnology Cat# sc-8066) were similar to this one (data not shown); C) rabbit polyclonal anti-TBR2 (Abcam Cat# ab23345). D-G) ACE2 expression has been detected in paraffine section of adult hippocampus, demonstrating specific expression of ACE2 (rabbit ati-ACE2 from Abcam) in astroglia in D, E and F (arrows), and pericytes in G (arrow). While ACE2-expressing cells are identified by brown-colored neurons were negative as we can observe in D by the white color (arrowhead). H) Double immunohistochemistry showing GFAP expression (brown) and ACE2 expression (black dots; arrows) in astroglial cells. I) Control section processed with GFAP and without ACE2 antibodies, showing the GFAP derived immunoreactivity and absence of ACE2 immunostaining. Scale bar: D-I) 50 µm. Supplementary Figure 2 is not the revised version and has to be changed by the uploaded one, which contains the revised lettering: Specificity of ACE2 expression in human lung, kidney and developing brain. A-C) The three antibodies show ACE2-specific immunoreaction in human lung in alveolar endothelial type II cells (arrows) and capillary endothelium (arrowheads). D-F) The three antibodies show ACE2-specific immunoreaction in human renal proximal tubule cells (arrows). G) Low power picture of a brain section processed in parallel by immunohistochemistry without primary ACE2 Sigma-Aldrich antibody and counterstained with Cresyl violet. H) High power picture of a brain section processed in parallel by immunohistochemistry without primary ACE2 R&D antibody and counterstained with Cresyl violet. Control sections without primary antibodies do not showed immunostaining. I-N) The three antibodies show ACE2-specific immunoreaction in DG progenitors and migrating cells in DGMS. Scale bar: A, B, C) 50 µm; D, E, F) 25 µm; G, I, K, M) 100 µm; J, L, N) 25 µm. DGMS: Dentate Gyrus Migratory Stream; IZ: Intermediate Zone; SVZ: Subventricular zone: VE: Ventricular Epithelium., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/353153
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353153
HANDLE: http://hdl.handle.net/10261/353153
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353153
PMID: http://hdl.handle.net/10261/353153
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353153
Ver en: http://hdl.handle.net/10261/353153
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353153

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353216
Dataset. 2023

CAR-EWAVES: EXTREME WAVES IN THE CARIBBEAN SEA FROM 1958 TO 2017

  • Morales-Márquez, Verónica
  • Cáceres-Euse, Alejandro
  • Hernández Carrasco, Ismael
  • Molcard, Anne
  • Orfila, Alejandro
Maximum monthly aggregate value of significant wave height for the Caribbean Sea from 1958 to 2017. The mean wave period, mean wave direction and the wind velocity (U10 and V10) related to the date of the maximum aggregation significant wave height value, are included in this dataset., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/353216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353216
HANDLE: http://hdl.handle.net/10261/353216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353216
PMID: http://hdl.handle.net/10261/353216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353216
Ver en: http://hdl.handle.net/10261/353216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353216

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353218
Dataset. 2024

SUPPORTING INFORMATION FOR C−H, N−H, AND O−H BOND ACTIVATIONS TO PREPARE PHOSPHORESCENT HYDRIDE-IRIDIUM(III)-PHOSPHINE EMITTERS WITH PHOTOCATALYTIC ACHIEVEMENT IN C−C COUPLING REACTIONS

  • Benítez, María
  • Buil, María L.
  • Esteruelas, Miguel A.
  • López, Ana M.
  • Martín-Escura, Cristina
  • Oñate, Enrique
-General information for the experimental section, NMR spectra, structural analysis, computational details and energies of optimized structures, experimental and computed UV/vis spectra, molecular orbitals, cyclic voltammograms, and normalized excitation and emission spectra (PDF) -Cartesian coordinates of the optimized structures (XYZ), Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/353218
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353218
HANDLE: http://hdl.handle.net/10261/353218
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353218
PMID: http://hdl.handle.net/10261/353218
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353218
Ver en: http://hdl.handle.net/10261/353218
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353218

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353271
Dataset. 2022

HOST DEVELOPMENTAL STAGES SHAPE THE EVOLUTION OF A PLANT RNA VIRUS [DATASET]

  • Melero, Izan
  • González, Rubén
  • Elena, Santiago F.
Datasets used in the generation of figures 1 and 2 of: Melero, I., González, R., Elena, S.F. 2022. Host developmental stages shape the evolution of a plant RNA Virus. Philos. Trans. R. Soc. B doi: 10.1098/rtsb.2022.0005, Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/353271
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353271
HANDLE: http://hdl.handle.net/10261/353271
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353271
PMID: http://hdl.handle.net/10261/353271
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353271
Ver en: http://hdl.handle.net/10261/353271
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/353271

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