Resultados totales (Incluyendo duplicados): 35619
Encontrada(s) 3562 página(s)
Encontrada(s) 3562 página(s)
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352335
Dataset. 2023
DETECTION OF CI SUBUNITS IN NDUFS4−/− MACROPHAGES [DATASET]
- Serrano-Lorenzo, Pablo
- Gobelli, Dino
- Garrido-Moraga, Rocío
- Esteban-Amo, María J.
- López-López, José R.
- Orduña, Antonio
- Fuente, Miguel A. de la
- Martín, Miguel Ángel
- Simarro-Grande, María
Left panel, Western blot for NDUFV1 (N module) and NDUFA9 (Q module). ATP5B and Coomassie staining were used as loading controls. Right panel, schematic representation of CI. The N module contains an NADH oxidation site, while the Q module contains a ubiquinone reduction site. P module is involved in proton-pumping activity. The positions of NDUFV1 and NDUFA9 are indicated. IMM, inner mitochondrial membrane; IMS, intermembrane space., Peer reviewed
Proyecto: //
DOI: http://hdl.handle.net/10261/352335
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352335
HANDLE: http://hdl.handle.net/10261/352335
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352335
PMID: http://hdl.handle.net/10261/352335
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352335
Ver en: http://hdl.handle.net/10261/352335
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352335
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352336
Dataset. 2023
ROLE OF NDUFS4 IN THE PROLIFERATION OF MACROPHAGES [DATASET]
- Serrano-Lorenzo, Pablo
- Gobelli, Dino
- Garrido-Moraga, Rocío
- Esteban-Amo, María J.
- López-López, José R.
- Orduña, Antonio
- Fuente, Miguel A. de la
- Martín, Miguel Ángel
- Simarro-Grande, María
Parental and Ndufs4−/− RAW 264.7 cells (1,000) were plated on 96-well plates. The number of viable cells was determined at the indicated time points. Each point represents a biological replicate. Data are shown as the mean ± SD., Peer reviewed
Proyecto: //
DOI: http://hdl.handle.net/10261/352336
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352336
HANDLE: http://hdl.handle.net/10261/352336
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352336
PMID: http://hdl.handle.net/10261/352336
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352336
Ver en: http://hdl.handle.net/10261/352336
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352336
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352337
Dataset. 2023
MITOROS LEVELS AND MMP IN NDUFS4−/− MACROPHAGES [DATASET]
- Serrano-Lorenzo, Pablo
- Gobelli, Dino
- Garrido-Moraga, Rocío
- Esteban-Amo, María J.
- López-López, José R.
- Orduña, Antonio
- Fuente, Miguel A. de la
- Martín, Miguel Ángel
- Simarro-Grande, María
(A) Representative flow cytometry histograms of MitoSOX staining (left) and graph showing relative mitoROS levels (right). (B) Representative flow cytometry histograms (left) of MitoTracker Red CMXRos staining (for MMP) and MitoTracker Green staining (for total mitochondrial mass) and graph showing the ratio of MMP over mitochondrial mass to more accurately determine the potential differences per unit of mitochondrial mass (right). *, P <0.05; **, P <0.01; ***, P<0.005; ****, P<0.001. Each point represents a biological replicate. Data are shown as the mean ± SEM., Peer reviewed
Proyecto: //
DOI: http://hdl.handle.net/10261/352337, https://doi.org/10.20350/digitalCSIC/16186
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352337
HANDLE: http://hdl.handle.net/10261/352337, https://doi.org/10.20350/digitalCSIC/16186
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352337
PMID: http://hdl.handle.net/10261/352337, https://doi.org/10.20350/digitalCSIC/16186
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352337
Ver en: http://hdl.handle.net/10261/352337, https://doi.org/10.20350/digitalCSIC/16186
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352337
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352341
Dataset. 2023
CI ACTIVITY IN NDUFS4−/− MACROPHAGES [DATASET]
- Serrano-Lorenzo, Pablo
- Gobelli, Dino
- Garrido-Moraga, Rocío
- Esteban-Amo, María J.
- López-López, José R.
- Orduña, Antonio
- Fuente, Miguel A. de la
- Martín, Miguel Ángel
- Simarro-Grande, María
The data shown in Fig 2A were reanalyzed and CI activity is shown as CI/CII (left panel) and CI/CIV (right panel). *, P <0.05; **, P <0.01; ***, P<0.005; ****, P<0.001. Each point represents a biological replicate. Data are shown as the mean ± SEM., Peer reviewed
Proyecto: //
DOI: http://hdl.handle.net/10261/352341
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352341
HANDLE: http://hdl.handle.net/10261/352341
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352341
PMID: http://hdl.handle.net/10261/352341
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352341
Ver en: http://hdl.handle.net/10261/352341
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352341
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352342
Dataset. 2023
PRIMER SEQUENCES [DATASET]
- Serrano-Lorenzo, Pablo
- Gobelli, Dino
- Garrido-Moraga, Rocío
- Esteban-Amo, María J.
- López-López, José R.
- Orduña, Antonio
- Fuente, Miguel A. de la
- Martín, Miguel Ángel
- Simarro-Grande, María
Increasing evidence demonstrate that the electron transfer chain plays a critical role in controlling the effector functions of macrophages. In this work, we have generated a Ndufs4−/− murine macrophage cell lines. The Ndufs4 gene, which encodes a supernumerary subunit of complex I, is a mutational hotspot in Leigh syndrome patients. Ndufs4−/− macrophages showed decreased complex I activity, altered complex I assembly, and lower levels of maximal respiration and ATP production. These mitochondrial respiration alterations were associated with a shift towards a pro-inflammatory cytokine profile after lipopolysaccharide challenge and improved ability to phagocytose Gram-negative bacteria., Peer reviewed
Proyecto: //
DOI: http://hdl.handle.net/10261/352342
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352342
HANDLE: http://hdl.handle.net/10261/352342
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352342
PMID: http://hdl.handle.net/10261/352342
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352342
Ver en: http://hdl.handle.net/10261/352342
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352342
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352386
Dataset. 2023
A GENERAL MODEL FOR THE MOTION OF MULTIVALENT CARGO INTERACTING WITH SUBSTRATES: CODES
- Mosby, L. S.
- Straube, A.
- Polin, Marco
Copy of the codes used for the manuscript "A General Model for the Motion of Multivalent Cargo Interacting with Substrates". More informations are available in the README file., This work was funded through a Leverhulme Trust Research Project Grant (RPG-2016-260) and a Wellcome Trust In- vestigator Award (200870/Z/16/Z) to A.S.. M.P. acknowledges support of the Ram ́on y Cajal Program (RYC-2018-02534)., Peer reviewed
Proyecto: AEI/RYC-2018-02534/
DOI: http://hdl.handle.net/10261/352386
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352386
HANDLE: http://hdl.handle.net/10261/352386
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352386
PMID: http://hdl.handle.net/10261/352386
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352386
Ver en: http://hdl.handle.net/10261/352386
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352386
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352397
Dataset. 2024
SUPPLEMENTARY MATERIAL TO: UNVEILING THE INHERENT PHYSICAL-CHEMICAL DYNAMICS: DIRECT MEASUREMENTS OF HYDROTHERMAL FLUID FLOW, HEAT, AND NUTRIENT OUTFLOW AT THE TAGORO SUBMARINE VOLCANO (CANARY ISLANDS, SPAIN)
- Martín-Díaz, Juan Pablo
- González-Vega, Alba
- Barreyre, Thibaut
- Cornide, Bernardo
- Arrieta López de Uralde, Jesús M.
- Vázquez, Juan Tomás
- Palomino, Desirée
- Lozano Rodríguez, José Antonio
- Escánez, José
- Presas-Navarro, Carmen
- Fraile-Nuez, Eugenio
3 tablas suplementarias, Peer reviewed
Proyecto: //
DOI: http://hdl.handle.net/10261/352397
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352397
HANDLE: http://hdl.handle.net/10261/352397
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352397
PMID: http://hdl.handle.net/10261/352397
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352397
Ver en: http://hdl.handle.net/10261/352397
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352397
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352403
Dataset. 2023
SUPPLEMENTARY MATERIAL FROM A GENERAL MODEL FOR THE MOTION OF MULTIVALENT CARGO INTERACTING WITH SUBSTRATES
- Mosby, L. S.
- Straube, A.
- Polin, Marco
Explicit derivations, supplementary figures and tables of parameter values., Peer reviewed
Proyecto: //
DOI: http://hdl.handle.net/10261/352403
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352403
HANDLE: http://hdl.handle.net/10261/352403
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352403
PMID: http://hdl.handle.net/10261/352403
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352403
Ver en: http://hdl.handle.net/10261/352403
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352403
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352420
Dataset. 2024
GAVÍN-CENTOL ET AL. 2024. EU BAIT-LAMINA DATASET TO DROUGHT IMPAIRS DETRITIVORE FEEDING ACTIVITY MORE STRONGLY IN NORTHERN THAN IN SOUTHERN EUROPEAN LATITUDES
- Gavín-Centol, M.P.
- Serrano-Carnero, D.
- Montserrat, M.
- Balanzategui, I.
- Scheu, Stefan
- Truu, J.
- Birkhofer, K.
- Sánchez-Moreno, S.
- Moya-Laraño, Jordi
This work was financed by the BiodivERsA COFUND (2015–2016 call), as well as by various national funders: the Swiss National Science Foundation (SNSF), the German Research Foundation (DFG), the Swedish Research Council (Formas), the Estonian Research Council (ETAG), and the Spanish Ministry of Science and Innovation (MICIN, ref.: PCIN-2016-045). Grant PID2019-103863RB-I00 and the associated predoctoral contract to the first author MPGC (ref.: PRE2020-095020) were funded by MCIN/AEI/10.13039/501100011033 and by “ESF Investing in your future”., 1. EU Bait-Lamina GLMM DB - Gavin-Centol et al.xls.-- 2. EU Bait-Lamina RF DB - Gavin-Centol et al.xls, Peer reviewed
DOI: http://hdl.handle.net/10261/352420, https://doi.org/10.20350/digitalCSIC/16190
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352420
HANDLE: http://hdl.handle.net/10261/352420, https://doi.org/10.20350/digitalCSIC/16190
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352420
PMID: http://hdl.handle.net/10261/352420, https://doi.org/10.20350/digitalCSIC/16190
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352420
Ver en: http://hdl.handle.net/10261/352420, https://doi.org/10.20350/digitalCSIC/16190
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352420
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352456
Dataset. 2023
ONE METER INTEGRATED DEPTH VELOCITY (TOTAL, AGEOSTROPHY, EKMAN AND STOKES COMPONENTS) FIELDS FOR THE MEDITERRANEAN SEA EACH 6 HOURS (FROM 2005 TO 2006)
- Morales-Márquez, Verónica
- Hernández Carrasco, Ismael
- Orfila, Alejandro
One meter integrated depth surface velocity fields for the Mediterranean Sea from January 2005 to January 2006 calculated following the methodology in Morales-Marquez et al.(2020). This dataset provides the total velocity field, the ageostrophic, Ekman and Stokes components., Peer reviewed
Proyecto: //
DOI: http://hdl.handle.net/10261/352456
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352456
HANDLE: http://hdl.handle.net/10261/352456
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352456
PMID: http://hdl.handle.net/10261/352456
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352456
Ver en: http://hdl.handle.net/10261/352456
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352456
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