BUSCADOR RECOLECTA

Supplementary Material of the article "Association of HCG20 and LINC00243 with schizophrenia and bipolar disorder through the regulation of DDR1 transcript expression in the adult brain dorsolateral prefrontal cortex". Article prepared to be submitted. It contains the results derived from the analyses performed to study whether the long non coding RNAs (lncRNAs) HCG20 and LINC00243 regulate DDR1 transcript expression in brain, particularly: Table S1. Expression levels of the HCG20, LINC02570, DDR1-DT and DDR1 transcripts included. Table S2. Blocks of linkage disequilibrium in the HCG20-DDR1 estimated by PLINK. Table S3. List of SNPs associated with schizophrenia or bipolar disorder in the latest genome-wide and candidate gene association analyses. Table S4. Complementarity hits between lncRNAs and DDR1. Table S5. Correlations between lncRNAs and DDR1 transcripts in healthy controls. Table S6. Mediation analyses between lncRNAs trnascripts, DDR1 transcripts and the diagnoses of schizophrenia and bipolar disorder. Table S7. Differential expression analyses of lncRNAs in schizophrenia and bipolar disorder. Table S8. List of eQTLs for lncRNAs and DDR1 transcripts in the HCG20-DDR1 locus.

Supplementary Material of the article: Processing speed mediates the relationship between DDR1 and psychosocial functioning in euthymic patients with bipolar disorder presenting psychotic symptoms, which is aimed to finding genetic variants associated to the diagnosis, neurocognitive performance, psychosocial functioning and white matter microstructure of patients with bipolar disorder. Particularly: Figre S1. Effect of rs1264323AA-rs2267641AC/CC on psychosocial functioning in patients with BD with psychotic symptoms. Table S1. SNP association tests in the whole patient sample and in the subsamples of bipolar disorder with and without psychotic symptoms. Table S2. SNP-SNP association tests in the whole patient sample and in the subsamples of bipolar disorder with and without psychotic symptoms. Table S3. Linear regression models of the neurocognition assessment in all participants. Table S4. Linear regression models of the neurocognition assessment healthy controls. Table S5. Linear regression models of the neurocognition assessment in patients with BD. Table S6. Linear regression models of the neurocognition assessment in patients with BD withpsychotic symptoms.

Supplementary material of the Article "Coexpression of the discoidin domain receptor 1 gene with oligodendrocyte-related and schizophrenia risk genes in the developing and adult human brain". It contains the data derived form a stuy aimed at identifying the genes that coexpressed with DDR1 in different stages of brain development, particularly: Figure S1. Spatiotemporal expression levels of DDR1, collagen, oligodendrocyte and myelin genes in human brain. Figure S2. Module eigengenes (ME) correlations with sample characteristics at each period studied. Figure S3. Gene overlap between each module identified and the pre-defined cell type modules according to Miller and cols (2010) in each developmental period. Figure S4. Cell type expression of DDR1 in prenatal and adult human brain. Table S1: Sample description. Table S2: Module correspondence. Table S3: List of genes in each DDR1 module according to time interval. Table S4: Module localization of oligodendrocyte, myelin, astrocyte, microglia and collagen genes. Table S5: Gene overlap with premade gene-lists from Cahoy et al. in the DDR1-modules. Table S6: Pathway enrichment in the DDR1-module in I-1. Table S7: Pathway enrichment in the DDR1-module in I-2. Table S8: Pathway enrichment in the DDR1-module in I-3. Table S9: Pathway enrichment in the DDR1-module in I-4. Table S10: Overlapp of genes between DDR1-module and SCZ-susceptibility genes according to time interval.

The trial was conducted in the Pamplona metropolitan area (Navarra, Spain). Patients were enrolled between July 31, 2020 and September 11, 2020 and randomized in a 1:1 ratio to ivermectin (400 mcg/kg) single oral dose or placebo. Assessments on enrollment and at days 4, 7, 14, 21 and 28 post treatment included: general symptoms report, physical examination and adverse events. All patients were asked to complete a daily online diary of symptoms from day 1 to 28 post treatment. On enrollment, as well as on days 7 and 14 blood samples were obtained to assess full blood count, C reactive protein, procalcitonin, ferritin, creatinine phosphokinase, lactic dehydrogenase, troponin T, D dimer, IL-6, and renal function. Viral loads were calculated at enrollment and on days 4, 7, 14 and 21 post treatment based on a nasopharyngeal swab for SARS-CoV-2 PCR (for genes N and E). A semi-quantitative serology for IgG against SARS-CoV-2 was done on samples from all patients on day 21 post-treatment.

This dataset contains:
- Raw time series recorded at a long-period MT site located on La Palma (Canary Islands) during and after the 2021 volcanic eruption.
- Figures showing the evolution of the time series and the resultant impedance tensor.
Time series are provided to support the results shown in the related publication. No Derivatives license.

This dataset contains two sets of adjective-noun phrases, one with color terms and one with intensional adjectives. - colorANdataset.csv: Color dataset. Contains 369 ANs tagged as intersective (1), subsective (2), or idiomatic (3). More than one label in case of polysemy. - intensionalANdataset.csv: Intensional dataset. Contains 1192 ANs in the semantic space with a preselected list of 10 intensional adjectives: apparent, artificial, false, former, future, likely, past, possible, potential, theoretical.

This dataset contains 1,600 adjective-noun phrases, divided into intensional (I) and non-intensional (N).

Raw data for participants that answered the Statistical Anxiety Test. A sample of 681 undergraduate Spanish students (80% women) of a Grade in Psychology, aged 18-60 years (M = 20.5, SD = 4.9), completed the computer version of the test. Raw responses and the time to response each item were recorded. The test included a scale to assess social desirability In addition, the examination mark in a test about statistic was recorded for a set or participants (N=430). Total scores were computed as an addition to item responses. ORION factor score estimates in the scales of the test were obtained using factor analysis (ULS extraction, Robust Promin, and ORION scores estimates). The software used to compute the factor analysis was FACTOR. The information provided is: sample descriptives, participants' responses, item response times, and participants' scores in test scales.

Se presentan resultados de la investigación evaluativa de carácter participativo realizada en Castell-Platja d’Aro (Girona) centrada en el análisis del modelo de trabajo que se desarrolla es el municipio y que se conoce como modelo relacional-vincular. Concretamente en el dataset se presentan datos que hacen referencia al trabajo en red desarrollado en el municipio. Los datos se recogieron en relación a seis programas socioeducativos que tenían una trayectoria de 15 años o más en la aplicación del modelo analizado a través de entrevistas semiestructuradas [1] y cuestionarios [2] Los resultados hacen referencia a los efectos del trabajo en red sobre los procesos de inclusión social. Los efectos que los profesionales destacan hacen referencia a la mejora de la coordinación de los servicios del municipio y a la adaptación de estos a las necesidades de la ciudadanía, así como, también, al desarrollo de actuaciones preventivas para la mejora de la cohesión social de la comunidad. Por otro lado, el análisis de la percepción de los participantes en los diversos programas permite afirmar que este modelo de trabajo facilita la atención centrada en la persona y una mayor implicación y corresponsabilidad de los participantes. Los datos que se pueden consultar en el presente Dataset son: [1] Guiones entrevista semiestructuradas (a profesionales, agentes clave del territorio, participantes en los programas analizados, cargos electos); [2] Guiones de los cuestionarios para participantes en los programas de (adolescencia, espacios familiares, aula de adultos, personas mayores y acogida y convivencia), [3] Resultados cualitativos categoría trabajo en red y [4] Matriz datos cuantitativos cuestionarios.

The dataset shows individual responses to the last round of a Delphi study with health professionals. The study aims to evaluate the content validity of the ICF-CSs for schizophrenia from the perspective of experts in the treatment of this population, as well as to identify the potential repercussions of this health condition in the functioning of people diagnosed with this disorder. The results provide important support for the worldwide content validity of the ICF-CSs for schizophrenia from the expert perspective and highlight the relevance, in the evaluation and treatment of people with schizophrenia, of assessing functioning by considering the body functions, participation in activities, environmental aspects and personal factors that experts have identified.