Resultados de investigación

Additional file 1. Additional figures and tables., Peer reviewed

Figure S1: Photos of the prepared SILMs: A) IL-based SILM (RPBI-IL); B) MIL-based SILM (RPBI-MIL); C) PIL-based SILM (RPBI-PIL), Figure S2: Schematic of the phase inversion steps: (A) polymer solution casting on clean glass plate; (B) System immersed in a coagulation bath with solvent mixture 50:50% of NMP: water; (C) Glass plate with the formed PBI support immersed in pure water, Figure S3: Schematic of the lab-scale experimental set-up used for single gas permeation measurements., Peer reviewed

This document contains the Supplementary Material to the article published under the same name. We outline the derivation of the Hamiltonian in the main text from first principles. During this process we also derive the general Hamiltonian for all cavity modes (including non-resonant terms) which could be useful for future investigations. We show how the inclusion of only the fundamental mode l = (0, 1, 1) is valid for the parameters considered in the main text. Finally we extend the model to include image dipoles, and show that the omission of these and nonresonant terms was valid in the main text., Peer reviewed

General information for the experimental section, NMR spectra, and structural analysis., Peer reviewed

Human-transformed residuals, especially those derived from human waste (dumps), farmland and livestock are involved in the emergence of antibiotic-resistant bacteria (ARB) in the environment. Wildlife can act as vectors of ARB dispersal through different environments, but also as sentinels to detect the early spread and determine ARB sources. The development of integrated monitoring programs focused on wildlife would help to anticipate the risks of ARB to humans and livestock. We used the yellow-legged gull (Larus michahellis) as a model species to investigate and monitor the spatial patterns of ARB dispersal across an extensive farmland region located in north-eastern Spain (Lleida). By integrating GPS tracking data and ARB clinical testing for 26 individuals within a network analysis framework, we modelled the risk of spatial pathogen spread through faeces during the bacteria-transmission latency period (16 days after sample collection). Additionally, we created a connectivity network to determine the main sources of ARB in the area, focusing on three main habitats of special risk for infection: dumps, livestock facilities and irrigation ponds. Seven individuals were infected by Escherichia coli, with one also co-infected with Listeria monocytogenes and Salmonella spp. Potential pathogen dispersal distances ranged from 1.13 km to 23.13 km from the breeding colony. Our network analyses revealed 54 main nodes (i.e., high-risk habitats recurrently visited by tracked gulls) and 1,182 links among them. Our findings revealed a high degree of connectivity between the breeding area, located in a shallow lake and nearby dumps, highlighting them as significant contributors to ARB dispersal. The integration of GPS data, pathogen testing and network analyses can shed further light on pathogen dynamics by creating spatial risk maps and identifying ARB sources. In combination with complementary molecular epidemiology techniques within a One Health framework, our approach can emerge as an important tool for monitoring ARB dynamics within highly human-transformed ecosystems. This may empower managers for the development of targeted ARB monitoring programmes and effective mitigation strategies, ultimately improving both animal and public health., This study is part of the Intramural CSIC Project “Opportunistic gulls as sentinel species to monitor urban marine ecosystems”. Infraestructures de la Generalitat de Catalunya S.A.U. funded some of the GPS devices. VMV was supported by Juan de la Cierva fellowship from the Spanish Government (JDC2022-049638-I)., With the institutional support of the ‘Severo Ochoa Centre of Excellence’ accreditation (CEX2019-000928-S), Peer reviewed

The dataset includes data on particle characterization of debris collected from wear-corrosion tests and blood analysis from rats after 30 days of inoculation. Particle size distribution of the debris was measured using a MasterSizer 3000 with laser diffraction technology. This device features a red He-Ne laser (wavelength: 632.8 nm), a blue LED laser (wavelength: 470 nm), and a Hydro SV small volume dispersion unit with stirring. Measurements were taken with laser obscuration set between 3% and 15%, and sample dispersion was achieved at 1200 rpm. Two debris samples were analyzed, each with three measurements. The dataset contains six files, each with two columns labeled "size" and "volume."Blood analysis was conducted prior to euthanizing the animals in a CO2 chamber, with 1.5 mL of intracardiac blood extracted. Serum samples were prepared by centrifugation at 3,000 x g for 15 minutes, then separated and stored in 1.5 mL Eppendorf tubes in a cold chamber for transport to a laboratory. Hematological analysis was performed by UNILABS (Madrid, Spain) using a Sysmex Kx-21n hematology autoanalyzer (Sysmex Corporation, Kobe, Japan). The dataset file consists of 21 columns, detailing results by treatment group (Serum control, Hyaluronic acid, and Graphene) and particle concentrations (0.63 mg/ml, 1.83 mg/ml, 1.65 mg/ml, and 2.35 mg/ml). Hematological parameters in the dataset include hemoglobin (Hgb), hematocrit (Hct), white blood cell (WBC) count, red blood cell (RBC) count, mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), and platelet (PLT) count. Biochemical parameters measured in serum samples are creatinine (Crea), aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), total protein (TP), triglycerides (TG), and cholesterol (CHO). Coagulation parameters include prothrombin time (PT), thromboplastin time (TT), and fibrinogen (F)., [EN] This is the experimental dataset used in the paper "Hematological response to particle debris generated during wear–corrosion processes of CoCr surfaces modified with graphene oxide and hyaluronic acid for joint prostheses". The paper includes the results of the potential biological responses and consequences of wear-corrosion processes associated with CoCr surfaces modified with graphene oxide and hyaluronic acid (CoCr-GO-HA), through in vitro (macrophage cultures) and in vivo (rat models) assays. Once the graphene oxide functionalized with hyaluronic acid was deposited on CoCr surfaces, wear-corrosion tests were performed by applying a 5N load at a rotational speed of 120 rpm over 30,000 m (682,000 cycles) in an aqueous solution of 3 g/L hyaluronic acid (HA), continuously recirculated during the experiment. The generated particles were collected and redispersed in 0.9% NaCl at concentrations of 0.63 mg/mL, 1.65 mg/mL, 1.83 mg/mL, and 2.35 mg/mL. The particles were intra-articularly injected into the knees of rats. This dataset includes the results of the wear particle characterization and the hematological analysis and biochemical parameters, 30 days after intra-articular knee injection in rats. Whole-blood hematological parameters included hemoglobin (Hgb), hematocrit (Hct), white blood cell (WBC) count, red blood cell (RBC) count, mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), and platelet (PLT) count., [ES] Este es el conjunto de datos experimentales utilizado en el artículo "Respuesta hematológica a los desechos de partículas generados durante los procesos de desgaste-corrosión de superficies de CoCr modificadas con óxido de grafeno y ácido hialurónico para prótesis articulares". El artículo incluye los resultados de las posibles respuestas biológicas y consecuencias de los procesos de desgaste-corrosión asociados con superficies de CoCr modificadas con óxido de grafeno y ácido hialurónico (CoCr-GO-HA), mediante ensayos in vitro (cultivos de macrófagos) e in vivo (modelos de ratas). Una vez depositado el óxido de grafeno funcionalizado con ácido hialurónico sobre superficies de CoCr, se realizaron ensayos de desgaste-corrosión aplicando una carga de 5N a una velocidad de rotación de 120 rpm durante 30,000 m (682,000 ciclos) en una solución acuosa 3 g/L de ácido hialurónico (HA), recirculada continuamente durante el experimento. Las partículas generadas se recogieron y se redispersaron en NaCl al 0.9%, a concentraciones de 0.63 mg/mL, 1.65 mg/mL, 1.83 mg/mL y 2.35 mg/mL. Las partículas fueron inyectadas intra-articularmente en rodilla de ratas. Este conjunto de datos incluye los resultados de la caracterización de partículas generadas durante los experimentos de desgaste-corrosión y los análisis hematológicos y parámetros bioquímicos después de 30 días de la inyección intraarticular en las rodillas de las ratas. Los parámetros hematológicos de sangre completa incluyeron hemoglobina (Hgb), hematocrito (Hct), conteo de glóbulos blancos (WBC), conteo de glóbulos rojos (RBC), volumen corpuscular medio (MCV), concentración media de hemoglobina corpuscular (MCHC) y conteo de plaquetas (PLT)., Ministerio de Ciencia e Innovación (MCIN), No

TG-MS profiles of GO under air flow and under a 1% v/v of O2 in N2 flow, the XRD of starting graphite and of GO and Raman spectrum of GO, the TG-MS profiles of CA–GO nanocomposites under air flow and the X-ray diffraction pattern of GO after CA removal, to complete the characterization., Peer reviewed

-(Figure S1) Thermographic image of a free-standing rectangular-shaped LCE strip (90 μm thick) with uniaxial orientation and (50 mW/cm2 illumination) (Figure S2) photoresponse of a dog bone-shaped LCE strip with uniaxial orientation under a sequence of ten pulses (50 mW/cm2illumination) (PDF). -(Movie S1) Light actuation of a rectangular LCE strip (90 μm thick) with uniaxial orientation (50 mW/cm2 illumination) (AVI). -(Movie S2) Light actuation of a rectangular LCE strip (90 μm thick) with uniaxial orientation (200 mW/cm2 illumination) (AVI)., Peer reviewed

Fitted Fe 2p3/2 and 3p XPS spectra of samples Fe-MNP, Mn-MNP, and Ni-MNP, including the respective tables with main parameters obtained from the XPS analyses; UV–visible spectrophotometry results; concentration of the free radicals of the different samples as a function of the reaction time measured by EPR; concentration of free radicals as a function of time reaction measured by EPR for sample Fe-MNP at different temperatures (25 and 40 °C) and pHs (4.8 and 7.0); and time dependence of [•OH] and [•OOH] for samples Fe-MNP, Mn-MNP, and Ni-MNP in acetate buffer (pH 4.8) containing 0.1 M of phosphate and 1,10-phenanthroline., Peer reviewed

Figures showing TEM micrographs and particle size distributions of MNPs under various conditions and TEM images of iron oxide nanostructures., Peer reviewed