BUSCADOR RECOLECTA

General information for the experimental section, structural analysis, computational details and energies of optimized structures, experimental and computed UV/vis spectra, cyclic voltammograms, frontier orbitals, normalized excitation and emission spectra, and NMR spectra. (PDF) Cartesian coordinates of the optimized structures. (XYZ), Peer reviewed

The PDF file includes: Supplementary Text; Materials and Methods; Figs. S1 to S10; Tables S1 to S15; References.-- Other Supplementary Material for this manuscript includes the following: MDAR Reproducibility Checklist; Data S1 to S5; Model and Scripts, No

Datapoints for correlation functions in Figures 2,4,5 and 6., Peer reviewed

In this folder you can find the morphological dataset and the phylogenetic data necessary for the analyses described in the 'software' folder. # Morphological data These are the linear measurements in millimeters of Pristurus specimens (morpho_pristurus.csv) and the average for each species (morpho_sp_final.csv). The linear measurements are as follows: - SVL: Snout-Vent Length (Body size). - TrL: Trunk Length. - HL: Head Length. - HW: Head Width. - HH: Head Height. - Lhu: Length of the humerus. - Lun: Length of the ulna. - Lfe: Length of the femur. - Ltb: Length of the tibia. # Phylogenetic data Consensus tree in Nexus format (pristurus_tree_final.nex) and posterior phylogenetic trees in RDS format (posterior_pristurus_final.rds) of Pristurus, extracted from a published phylogeny of Afro-Arabian squamates (Tejero-Cicuéndez et al. 2021 Systematic Biology)., Species living in distinct habitats often experience unique ecological selective pressures, which can drive phenotypic divergence. However, how ecophenotypic patterns are affected by allometric trends and trait integration levels is less well understood. Here we evaluate the role of allometry in shaping body size and body form diversity in Pristurus geckos utilizing differing habitats. We found that patterns of allometry and integration in body form were distinct in species with different habitat preferences, with ground-dwelling Pristurus displaying the most divergent allometric trend and high levels of integration. There was also strong concordance between intraspecific allometry across individuals and evolutionary allometry among species, revealing that differences in body form among individuals were predictive of evolutionary changes across the phylogeny at macroevolutionary scales. This suggested that phenotypic evolution occurred along allometric lines of least resistance, with allometric trajectories imposing a strong influence on the magnitude and direction of size and shape changes across the phylogeny. When viewed in phylomorphospace, the largest rock-dwelling species were most similar to the smallest ground-dwelling species, and vice versa. Thus, in Pristurus, phenotypic evolution along the differing habitat-based allometric trajectories resulted in similar body forms at differing body sizes in distinct ecological habitats., MCIU/AEI/FEDER, UE, Award: PGC2018-098290-B-I00, European Commission, Award: PID2021-128901NB-I00, Agencia Estatal de Investigación, Award: FJC2021-046832-I, Alexander von Humboldt Foundation, The Neurosciences Foundation, Award: DBI-1902511, Peer reviewed

Appendix Expanded View Figures PDF Table EV1 Dataset EV1 Dataset EV2 Dataset EV3 Dataset EV4 Dataset EV5 Dataset EV6 Dataset EV7, Peer reviewed

A scheme of the p38 kinase family evolution in vertebrates., Peer reviewed

Alignment of the p38 consensus sequences of non-mammalian vertebrate lineages., Peer reviewed

Schematic representation of synteny conservation for p38 and p38/δ and plexin genes in animals, Peer reviewed

Supplementary Tables 1-7, Peer reviewed

The item contains Supplementary Files 1-4 for the manuscript "Evolutionary analysis of p38 stress activated kinases in unicellular relatives of animals suggest an ancestral function in osmotic stress", Peer reviewed