Resultados de investigación

17 pages. -- S1. Materials, methods and characterization. -- S1.1.Materials. -- S1.2.Methods. -- S1.3. Characterization. -- S2. Characterization of BCN-348. -- S2.1. Single-crystal X-ray diffraction. -- S2.2. Powder X-Ray Diffraction. -- S2.3. N2 sorption. -- S2.4. Thermogravimetric Analysis. -- S3. Heterogeneous degradation of simulant diisopropylfluorophosphate (DIFP) in unbuffered solution. -- S3.1. Gas Chromatographic (GC) studies. -- S3.2. 1 H and 31P-NMR studies. -- S4. Reference, Peer reviewed

This PDF file includes: Supplementary Text Figs. S1 to S7 Table S1, Peer reviewed

Table 1.DOCX Image 1.TIF Image 2.TIF Image 3.TIF Image 4.TIF Image 5.TIF Image 6.TIF, Peer reviewed

[Description of methods used for collection/generation of data] - Bioinformatics: DeepCLIP analysis (https://deepclip-web.compbio.sdu.dk/) - Sanger sequencing - Fluorescent Fragment Analysis., This dataset corresponds to a comprehensive study of the alternatively spliced exons 8 and 10 of the breast cancer susceptibility gene CHEK2. For this purpose, we have used a minigene with exons 6 to 10, where we introduced 12 internal microdeletions of exons 8 and 10 and 87 variants by site-directed mutagenesis that were assayed in MCF-7 cells. We identified three minimal (10,11,15-nt) regions essential for exon recognition. Thirty-eight variants impaired splicing, and 3 of which were classified as pathogenic/likely pathogenic variants according to ACMG/AMP (American College of Medical Genetics and Genomics/Association for Molecular Pathology)-based guidelines, so carrier patients and families may benefit from tailored prevention protocols and personalized therapies., EAV lab is supported by grants from the Spanish Ministry of Science and Innovation, Plan Nacional de I+D+I 2013-2016, ISCIII (PI20/00225) co-funded by FEDER from Regional Development European Funds (European Union). Lara Sanoguera-Miralles is supported by a predoctoral fellowship from the AECC-Scientific Foundation, Sede Provincial de Valladolid (2019–2023)., File: DeepCLIP_Predictions_Variants_exons_8_10.xlsx Folder: cDNA_Sequences. Transcript Sequencing: • 176 *.ab1 files of cDNA sequences of the wild type and mutant minigenes. Folder: Fragment_Analysis. Fluorescent Fragment Analysis: • 267 *.fsa files of fluorescent fragment analysis of the wild type and mutant sequences. Folder: Minigenes_Sequences. Sequence files of wild type and mutant constructs (89 *.ab1 files)., Peer reviewed

Appendix A. Supplementary material, Peer reviewed

Appendix A. Supplementary material, Peer reviewed

Multimedia component 1., Peer reviewed

12 pages. -- Figure S1-S18. -- Table S1. Atomic percentages determined by XPS in the electrodes after OER. -- Table S2. Comparison of the CoFeP-based electrodes for OER in 1 M KOH in chronological order., The development of high current density anodes for the oxygen evolution reaction (OER) is fundamental to manufacturing practical and reliable electrochemical cells. In this work, we have developed a bimetallic electrocatalyst based on cobalt–iron oxyhydroxide that shows outstanding performance for water oxidation. Such a catalyst is obtained from cobalt–iron phosphide nanorods that serve as sacrificial structures for the formation of a bimetallic oxyhydroxide through phosphorous loss concomitantly to oxygen/hydroxide incorporation. CoFeP nanorods are synthesized using a scalable method using triphenyl phosphite as a phosphorous precursor. They are deposited without the use of binders on nickel foam to enable fast electron transport, a highly effective surface area, and a high density of active sites. The morphological and chemical transformation of the CoFeP nanoparticles is analyzed and compared with the monometallic cobalt phosphide in alkaline media and under anodic potentials. The resulting bimetallic electrode presents a Tafel slope as low as 42 mV dec–1 and low overpotentials for OER. For the first time, an anion exchange membrane electrolysis device with an integrated CoFeP-based anode was tested at a high current density of 1 A cm–2, demonstrating excellent stability and Faradaic efficiency near 100%. This work opens up a way for using metal phosphide-based anodes for practical fuel electrosynthesis devices., Peer reviewed

2 pages. -- A. Influence of the radiative coating on the optical properties of a copper surface. -- Figure S1. a) Bare and b) radiative coated copper slabs. The rainbow colours appearing on the radiative coated slab result from the light diffraction due to the periodic structure. -- Figure S2. a) UV-Vis and b) IR spectra of bare (b-Cu) and b) radiative coated copper slabs (RC-Cu)., Peer reviewed

ehf214186-sup-0001-Supplementary Material.docxWord 2007 document , 516.4 KB, Peer reviewed