Resultados totales (Incluyendo duplicados): 45302
Encontrada(s) 4531 página(s)
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
Dataset. 2022

TABLE1_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.DOCX

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G.
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
HANDLE: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
PMID: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
Ver en: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
Dataset. 2022

SUPPLEMENTARY MATERIALS FOR UNDERSTANDING THE GASTROINTESTINAL BEHAVIOR OF THE COFFEE PULP PHENOLIC COMPOUNDS UNDER SIMULATED CONDITIONS

  • Cañas, Silvia
  • Rebollo-Hernanz, Miguel
  • Braojos, Cheyenne
  • Benitez, Vanesa
  • Ferreras-Charro, Rebeca
  • Dueñas, Montserrat
  • Aguilera, Yolanda
  • Martín-Cabrejas, María A.
The supporting information: Table S1: Retention index, bioaccessibility, and potential bioavailability (%) of phenolic families from coffee pulp flour (CPF) and extract (CPE) after in vitro digestion; Table S2: Physicochemical properties and intestinal absorption of the phenolic metabolites from the coffee pulp in silico colonic metabolism; Figure S1: Association between the molecular weight of the coffee pulp phenolic metabolites and their Caco-2 (A) and human intestinal (B) absorption., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
HANDLE: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
PMID: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
Ver en: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
Dataset. 2022

IMAGE5_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.JPEG

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
HANDLE: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
PMID: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
Ver en: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311243
Dataset. 2022

VALIDITY OF CONTINUOUS GLUCOSE MONITORING FOR CATEGORIZING GLYCEMIC RESPONSES TO DIET: IMPLICATIONS FOR USE IN PERSONALIZED NUTRITION [DATASET]

  • Merino, Jordi
  • Linenberg, Inbar
  • Bermingham, Kate M.
  • Ganesh, Sajaysurya
  • Bakker, Elco
  • Delahanty, Linda M.
  • Chan, Andrew T.
  • Capdevila Pujol, Joan
  • Wolf, Jonathan
  • Al Khatib, Haya
  • Franks, Paul W.
  • Spector, Tim D.
  • Ordovás, José M.
  • Berry, Sarah E.
  • Valdés, Ana M.
Data described in the article, code book, and analytic code are held with the Department of Twin Research at King’s College London and will be made available using our normal procedures overseen by the Wellcome Trust and its guidelines as part of our core funding., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311243
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311243
HANDLE: http://hdl.handle.net/10261/311243
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311243
PMID: http://hdl.handle.net/10261/311243
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311243
Ver en: http://hdl.handle.net/10261/311243
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311243

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311248
Dataset. 2022

SUPPLEMENTARY MATERIALS FOR EFFECTS OF A MEALWORM (TENEBRIO MOLITOR) EXTRACT ON METABOLIC SYNDROME-RELATED PATHOLOGIES: IN VITRO INSULIN SENSITIVITY, INFLAMMATORY RESPONSE, HYPOLIPIDEMIC ACTIVITY AND OXIDATIVE STRESS

  • Navarro del Hierro, Joaquín
  • Cantero-Bahillo, Emma
  • Fernández-Felipe, M. Teresa
  • Rodríguez García-Risco, Mónica
  • Fornari, Tiziana
  • Rada, Patricia
  • Doblado, Laura
  • Ferreira, Vítor
  • Hitos, Ana B.
  • Valverde, Ángela M.
  • Monsalve, María
  • Martín, Diana
The supporting information the whole blots of Western blot figures., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311248
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311248
HANDLE: http://hdl.handle.net/10261/311248
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311248
PMID: http://hdl.handle.net/10261/311248
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311248
Ver en: http://hdl.handle.net/10261/311248
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311248

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311249
Dataset. 2022

IMAGE4_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.JPEG

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G.
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311249
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311249
HANDLE: http://hdl.handle.net/10261/311249
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311249
PMID: http://hdl.handle.net/10261/311249
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311249
Ver en: http://hdl.handle.net/10261/311249
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311249

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311252
Dataset. 2022

IMAGE3_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.JPEG

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G.
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311252
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311252
HANDLE: http://hdl.handle.net/10261/311252
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311252
PMID: http://hdl.handle.net/10261/311252
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311252
Ver en: http://hdl.handle.net/10261/311252
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311252

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311254
Dataset. 2022

ASSESSMENT OF COCOA POWDER CHANGES DURING THE ALKALIZATION PROCESS USING UNTARGETED METABOLOMICS: APPENDIX A. SUPPLEMENTARY DATA

  • Greño, Maider
  • Herrero, Miguel
  • Cifuentes, Alejandro
  • Marina, María Luisa
  • Castro-Puyana, M.
Multimedia component 1., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311254
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311254
HANDLE: http://hdl.handle.net/10261/311254
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311254
PMID: http://hdl.handle.net/10261/311254
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311254
Ver en: http://hdl.handle.net/10261/311254
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311254

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311257
Dataset. 2022

IMAGE2_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.JPEG

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G.
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311257
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311257
HANDLE: http://hdl.handle.net/10261/311257
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311257
PMID: http://hdl.handle.net/10261/311257
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311257
Ver en: http://hdl.handle.net/10261/311257
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311257

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311261
Dataset. 2022

IMAGE1_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.JPEG

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G.
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311261
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311261
HANDLE: http://hdl.handle.net/10261/311261
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311261
PMID: http://hdl.handle.net/10261/311261
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311261
Ver en: http://hdl.handle.net/10261/311261
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311261

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