BUSCADOR RECOLECTA

The transcriptional regulator GLYR1 may mediate NNMT down-regulation., Peer reviewed

Alteration of SAM/SAH ratio transcriptionally regulates Nnmt and HMTs., Peer reviewed

Highly expressed histone methyltransferase genes are co-expressed., Peer reviewed

PEMT expression anticorrelate globally with levels of specific histone marks genome-wide in healthy tissues (related to Fig 3)., Peer reviewed

Relationship of other groups of methyltransferases to PEMT in healthy tissues., Peer reviewed

NNMT and HMT expression and relationship in cancer vs. normal samples., Peer reviewed

Relationship of other groups of methyltransferases to NNMT in cancers., Peer reviewed

2 tables, 2 figures, Supporting information for the article https://doi.org/10.3390/su14116472, Table S1 – Relative abundance of molecular species of fatty acids (expressed as % of total pool of fatty acids) of Hermetia illucens larvae fed with different substrates retrieved from the literature surveyed.-- Table S2: Dataset used on MetaboAnalist to perform the statistical analysis.-- Table S3 - Top 10 peer-reviewed scientific journals publishing scientific research addressing the fatty acid profile of Hermetia illucens retrieved from WoS™ and Scopus. (Journals publishing 5 or less articles on this topic were grouped as Others).-- Figure S1: Box plots and kernel density plots before and after normalization. The boxplots show at most 50 features due to space limitations. The density plots are based on all samples. Data transformation: Log Normalization; Data scaling: Autoscaling.-- Figure S2: Hierarchical clustering of substrates shown as dendrogram (distance measures using Euclidean, and clustering algorithm using Ward’s Distance).-- References, Peer reviewed

In melanoma NNMT expression is strongly anticorrelated with the histone methyltransferase-encoding gene SETDB1, a known driver of melanoma., Peer reviewed

Infiltration of specific immune cell types into primary tumours correlates positively with NNMT expression but does not strongly confound the HMT-NNMT relationship., Peer reviewed