Resultados totales (Incluyendo duplicados): 34260
Encontrada(s) 3426 página(s)
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311216
Dataset. 2022

SUPPORTING INFORMATION FOR PREBIOTIC POTENTIAL OF A NEW SWEETENER BASED ON GALACTOOLIGOSACCHARIDES AND MODIFIED MOGROSIDES

  • Muñoz Labrador, Ana
  • Lebrón-Aguilar, Rosa
  • Quintanilla-López, Jesús Eduardo
  • Galindo-Iranzo, Plácido
  • Azcarate, Silvana
  • Kolida, Sofía
  • Kachrimanidou, Vasiliki
  • García-Cañas, Virginia
  • Methven, Lisa
  • Rastall, Robert A.
  • Moreno, F. Javier
  • Hernández-Hernández, Oswaldo
Results of quantitative real-time PCR after in vitro fermentation at 10 and 24 h and statistical test data., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311216
HANDLE: http://hdl.handle.net/10261/311216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311216
PMID: http://hdl.handle.net/10261/311216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311216
Ver en: http://hdl.handle.net/10261/311216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311216

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311222
Dataset. 2022

SUPPLEMENTARY MATERIALS FOR ROS SUPPRESSION BY EGG WHITE HYDROLYSATE IN DOCA-SALT RATS—AN ALTERNATIVE TOOL AGAINST VASCULAR DYSFUNCTION IN SEVERE HYPERTENSION

  • Luz Abreu, Edina da
  • Rodrigues Moro, Camila
  • Kanaan, Samia Hassan Husein
  • Bernardino de Paula, Ricardo
  • Teixeira Herrera, Camila
  • Dorneles Costa, Pedro Henrique
  • Peçanha, Franck Maciel
  • Vassallo, Dalton Valentim
  • Venturini Rossoni, Luciana
  • Miguel, Marta
  • Wiggers, Giulia Alessandra
The supporting information: Figure S1: The role of EWH in NF-κB-induced impairment on acetylcholine (ACh) relaxation in MRA of DOCA-salt rats; Figure S2: The role of EWH in NO-mediated acetylcholine (ACh)-induced relaxation in the aorta of DOCA-salt rats; Figure S3: NO production is recovered by EWH treatment in aortic sections of DOCA-salt rats., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311222
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311222
HANDLE: http://hdl.handle.net/10261/311222
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311222
PMID: http://hdl.handle.net/10261/311222
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311222
Ver en: http://hdl.handle.net/10261/311222
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311222

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311227
Dataset. 2022

SUPPLEMENTARY MATERIALS FOR SUPPLEMENTATION WITH THE SYMBIOTIC FORMULATION PRODEFEN® INCREASES NEURONAL NITRIC OXIDE SYNTHASE AND DECREASES OXIDATIVE STRESS IN SUPERIOR MESENTERIC ARTERY FROM SPONTANEOUSLY HYPERTENSIVE RATS

  • Méndez-Albiñana, Pablo
  • Martínez-González, Miguel Ángel
  • Camacho-Rodríguez, Laura
  • Ferreira-Lazarte, Alvaro
  • Villamiel, Mar
  • Rodrigues-Díez, Raquel
  • Balfagón, Gloria
  • García-Redondo, Ana B.
  • Prieto-Nieto, Mª Isabel
  • Blanco-Rivero, Javier
The supporting information: Figure S1: (a) Systolic blood pressure from WKY, SHR-Ctrl and SHR-SYNB animals (Mean + S.E.M.; n = 11–14 animals each group) expressed in mm Hg. One-way ANOVA, followed by a Tukey post-hoc test was used as a statistical analysis. * p < 0.05 WKY vs. SHR-Ctrl; # p < 0.05 SHR-Ctrl vs. SHR-SYNB. + p < 0.05 WKY vs. SHR-SYNB. (b) EFS-induced NO release in mesenteric segments from WKY, SHR-Ctrl and SHR-SYNB animals (Mean + S.E.M.; n = 11–14 animals each group) expressed in arbitrary fluorescence units (A.F.U.)/mg tissue. One-way ANOVA, followed by a Tukey post-hoc test was used as a statistical analysis. * p < 0.05 WKY vs. SHR-Ctrl; # p < 0.05 SHR-Ctrl vs. SHR-SYNB. + p < 0.05 WKY vs. SHR-SYNB (c) Analysis of the functional role of neuronal NO on EFS-induced vasoconstriction by preincubation with the unspecific nitric oxide synthase (NOS) inhibitor L-NAME, in mesenteric arteries WKY rats. Results (mean ± S.E.M.) are expressed as a percentage of previous tone induced by KCl. n = 6 segments from different animals in each ex-perimental group., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311227
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311227
HANDLE: http://hdl.handle.net/10261/311227
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311227
PMID: http://hdl.handle.net/10261/311227
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311227
Ver en: http://hdl.handle.net/10261/311227
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311227

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
Dataset. 2022

TABLE1_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.DOCX

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G.
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
HANDLE: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
PMID: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
Ver en: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
Dataset. 2022

SUPPLEMENTARY MATERIALS FOR UNDERSTANDING THE GASTROINTESTINAL BEHAVIOR OF THE COFFEE PULP PHENOLIC COMPOUNDS UNDER SIMULATED CONDITIONS

  • Cañas, Silvia
  • Rebollo-Hernanz, Miguel
  • Braojos, Cheyenne
  • Benitez, Vanesa
  • Ferreras-Charro, Rebeca
  • Dueñas, Montserrat
  • Aguilera, Yolanda
  • Martín-Cabrejas, María A.
The supporting information: Table S1: Retention index, bioaccessibility, and potential bioavailability (%) of phenolic families from coffee pulp flour (CPF) and extract (CPE) after in vitro digestion; Table S2: Physicochemical properties and intestinal absorption of the phenolic metabolites from the coffee pulp in silico colonic metabolism; Figure S1: Association between the molecular weight of the coffee pulp phenolic metabolites and their Caco-2 (A) and human intestinal (B) absorption., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
HANDLE: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
PMID: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
Ver en: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
Dataset. 2022

IMAGE5_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.JPEG

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
HANDLE: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
PMID: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
Ver en: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311243
Dataset. 2022

VALIDITY OF CONTINUOUS GLUCOSE MONITORING FOR CATEGORIZING GLYCEMIC RESPONSES TO DIET: IMPLICATIONS FOR USE IN PERSONALIZED NUTRITION [DATASET]

  • Merino, Jordi
  • Linenberg, Inbar
  • Bermingham, Kate M.
  • Ganesh, Sajaysurya
  • Bakker, Elco
  • Delahanty, Linda M.
  • Chan, Andrew T.
  • Capdevila Pujol, Joan
  • Wolf, Jonathan
  • Al Khatib, Haya
  • Franks, Paul W.
  • Spector, Tim D.
  • Ordovás, José M.
  • Berry, Sarah E.
  • Valdés, Ana M.
Data described in the article, code book, and analytic code are held with the Department of Twin Research at King’s College London and will be made available using our normal procedures overseen by the Wellcome Trust and its guidelines as part of our core funding., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311243
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311243
HANDLE: http://hdl.handle.net/10261/311243
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311243
PMID: http://hdl.handle.net/10261/311243
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311243
Ver en: http://hdl.handle.net/10261/311243
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311243

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311248
Dataset. 2022

SUPPLEMENTARY MATERIALS FOR EFFECTS OF A MEALWORM (TENEBRIO MOLITOR) EXTRACT ON METABOLIC SYNDROME-RELATED PATHOLOGIES: IN VITRO INSULIN SENSITIVITY, INFLAMMATORY RESPONSE, HYPOLIPIDEMIC ACTIVITY AND OXIDATIVE STRESS

  • Navarro del Hierro, Joaquín
  • Cantero-Bahillo, Emma
  • Fernández-Felipe, M. Teresa
  • Rodríguez García-Risco, Mónica
  • Fornari, Tiziana
  • Rada, Patricia
  • Doblado, Laura
  • Ferreira, Vítor
  • Hitos, Ana B.
  • Valverde, Ángela M.
  • Monsalve, María
  • Martín, Diana
The supporting information the whole blots of Western blot figures., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311248
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311248
HANDLE: http://hdl.handle.net/10261/311248
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311248
PMID: http://hdl.handle.net/10261/311248
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311248
Ver en: http://hdl.handle.net/10261/311248
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311248

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311249
Dataset. 2022

IMAGE4_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.JPEG

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G.
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311249
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311249
HANDLE: http://hdl.handle.net/10261/311249
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311249
PMID: http://hdl.handle.net/10261/311249
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311249
Ver en: http://hdl.handle.net/10261/311249
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311249

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311252
Dataset. 2022

IMAGE3_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.JPEG

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G.
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311252
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311252
HANDLE: http://hdl.handle.net/10261/311252
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311252
PMID: http://hdl.handle.net/10261/311252
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311252
Ver en: http://hdl.handle.net/10261/311252
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311252

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