BUSCADOR RECOLECTA

Experimental data of "Extremely thermostabilizing core mutations in coiled-coil mi-metic proteins of HIV-1 gp41 produce diverse effects on target binding and inhibitory activity"

Corresponding author: Dr. Sergio Cantero Chinchilla. sergio.canterochinchilla@bristol.ac.uk // scanteroch@gmail.com Involved institutions: University of Nottingham (UK), University of the Basque Country (ES), Technological Institute of Aragón (ES), University of Granada (ES)., Ultrasonic guided-wave test data taken from a fatigue test experiment over a notched aluminium plate. Data summary.- Ultrasonic guided-wave test data: Frequency of excitation: 300 kHz (radial mode of vibration) Shape: sinusoid of 4 cycles Amplitude: 45 Vpp Sampling frequency: 60 kHz Fatigue test data.- Load type: Tension-Tension (using Instron 8850 servo-hydraulic fatigue testing machine) Minimum load: 1kN Maximum load: 10kN Frequency: 6Hz Number of cycles: 100 000 Specimen information.- Aluminum plate Alloy: QQA250/5 ‘O’ 2024 Dimensions: 245mm x 500mm x 1mm Central notch length: 22.5mm (centered with respect to the test sample centerline and machined using a laser cutting procedure) Further description.- The fatigue test has been performed using a middle tension [M(T)] specimen with a centered crack and loaded in tension using a positive loading ratio. A fatigue pre-cracking procedure was applied to develop a fresh and straight crack front to mitigate the effect of the machined started notch. The detection and monitoring of the crack onset and growth was carried out using two phased-arrays of six piezoelectric wafer active sensors (PWAS), one set as transmitter, the other as receiver. Piezoelectric ceramic disc transducers of 7mm diameter and 0.5mm thickness have been used in this fatigue test. They PWAS were placed symmetrically with regards to the sample centerline and bonded to the aluminum surface using a 3M Scotch-Weld DP490 epoxy adhesive (TradeMarks). File naming convention: “P_AL_S01_BF6.mat” or “P_AL_S01_BF6_XXX.mat” with XXX=1000, 2000, 3000, 100 000; P stands for Plate; AL stands for Aluminum; S01 stands for specimen 01; BF6 stands for Beamforming using 6 transducers; XXX are the number of cycles at which the fatigue test stopped and the ultrasonic guided-wave tests were performed (every 1000 fatigue cycle). Note 1: The file “P_AL_S01_BF6.mat” contains the data with the structure in pristine state. Note 2: The files “P_AL_S01_BF6_XXX.mat” contains the data after XXX fatigue cycles. Further details about the internal data structure of the MAT-files included within the Readme file within the dataset.

Metabolic reprogramming of cancer cells represents an orchestrated network of evolving molecular and functional adaptations during oncogenic progression. In particular, how metabolic reprogramming is orchestrated in breast cancer and its decisive role in the oncogenic process and tumor evolving adaptations are well consolidated at the molecular level. Nevertheless, potential correlations between functional metabolic features and breast cancer clinical classification still represent issues that have not been fully studied to date. Accordingly, we aimed to investigate whether breast cancer cell models representative of each clinical subtype might display different metabolic phenotypes that correlate with current clinical classifications. In the present work, functional metabolic profiling was performed for breast cancer cell models representative of each clinical subtype based on the combination of enzyme inhibitors for key metabolic pathways, and isotope-labeled tracing dynamic analysis. The results indicated the main metabolic phenotypes, so-called ‘metabophenotypes’, in terms of their dependency on glycolytic metabolism or their reliance on mitochondrial oxidative metabolism. The results showed that breast cancer cell subtypes display different metabophenotypes. Importantly, these metabophenotypes are clearly correlated with the current clinical classifications., Funding: This research, including APC charges, was funded by the Spanish Agencia Estatal de Investigación (Ministry of Science and Innovation) and the European Regional Development Fund [grant numbers CTQ2014-56370-R and CTQ2017-85658-R]; the Fundación Ramón Areces; and the initiative Solidaridad Entre Montañas.

Dataset of the paper "On the need of a unified methodology for processing Schumann resonance measurements" published in JGR Atmospheres.

This work was supported by grant CTQ2017–85658-R funded by MCIN/AEI/10.13039/501100011033/ FEDER “Una manera de hacer Europa” and grants PID2019–104366RB-C22 and PID2020–114256RBI00 funded by MCIN/AEI/10.13039/501100011033

This work was supported by the projects MAT2010-20370 and MAT2013-43922-R (European FEDER support included, MICINN, Spain), PI10/02295 (Instituto de Salud Carlos III, Fondo de Investigacion Sanitaria, FEDER funds) and P07-FQM2496, P10-CTS-6270 and P07-FQM3099 (Junta de Andalucia, Spain)., The aim of this data article is to provide data for a basic knowledge of the properties of lipid nanocapsules, a new colloidal system with very promising applications in drug delivery. Firstly, we pay attention on how it is possible to determine their surface composition by means of electrokinetics measurements. On the other hand, we provide experimental evidences for a better understanding of the factors that determine the interactions of these nanoparticles with cells as a necessary step to guide the design of the most effective formulations. Additionally, we supply information about encapsulation efficiency of docetaxel, a potent chemotherapy drug, inside nanocapsules supporting the experimental cytotoxicity results of these nanosystems., European Union (EU) MAT2010-20370 MAT2013-43922-R, Instituto de Salud Carlos III, Fondo de Investigacion Sanitaria, FEDER funds PI10/02295, Junta de Andalucia P07-FQM2496 P10-CTS-6270 P07-FQM3099, Spanish Government

Supplementary Tables 3-6, 8-10: Table S3. Trinotate annotation report for Dactylicapnos torulosa. Annotation through blastx and blastp for predict transcript against Swissprot database. Table S4. Trinotate annotation report for Fumaria bracteosa. Annotation through blastx and blastp for predict transcript against Swissprot database. Table S5. Trinotate annotation report for Roemeria refracta. Annotation through blastx and blastp for predict transcript against Swissprot database. Table S6. Eschscholzia californica annotation through blastx against Swissprot database for transcripome transcript aligned to reference. Qseqid, query or source (e.g., gene) sequence id; seqid, subject or target (e.g., reference genome) sequence id; pident, percentage of identical matches; length, alignment length (sequence overlap); mismatch, number of mismatches; gapopen, number of gap openings; qstart, start of alignment in query; qend, end of alignment in query; sstart, start of alignment in subject; send, end of alignment in subject; evalue, expect value; bitscore, bit score. Table S8. Transcripts annotated as transcription factor through PlantTFDB. Table S9. Genes differentially expressed between colpate and porate species. Annotation through BLASTX searching against the SwissProt Database. Table S10. Functional classification of differentially expressed genes (DEGs) between colpate and porate species using Blast2GO software. Sheet 1, Blast2GO output file with annotations and functional classification for each DEG. Sheet2, summary of the number of DEGs for each functional annotation within the three different functional categories, note that each DEG can have several annotation possibilities.

We present the data of a study of the Schumann Resonance (SR) regular variations (March 2013 – February 2017) using the ground-based magnetometers from the Sierra Nevada station, Spain (37◦02’N, 3◦19’W). The study is based on the fitting parameters obtained by the Lorentzian fit, calculated for each 10-min interval record, namely, peak amplitudes, central frequencies, width of the resonances and the power spectrum integral for the first 3 SR modes. We consider three time-scales in the study: seasonal, monthly and daily variations. The processed data collected by the Sierra Nevada station are also made public with this work.

Cuestionario y datos brutos de la investigación "El Proyecto Europa: un reto cultural", en español y en inglés., El artículo aborda la pregunta de por qué las mujeres migrantes se ven más negativamente afectadas que los hombres cuando se enfrentan a comportamientos de comunicación para ellos inusuales en el país de acogida, pero, sin embargo, están más dispuestas a adaptarse al estilo de comunicación extranjero. Para responder a esta pregunta, se investigó la gestión diferente de la regulación emocional por parte de ambos sexos. Una amplia encuesta realizada entre inmigrantes españoles en Alemania llevó a la conclusión de que las mujeres inmigrantes perciben los rasgos investigados con más frecuencia y también se ven más afectadas por ellos. Pero, en comparación con los hombres, tienen una mayor capacidad para reconocer y comprender sus emociones aunque también muestran una mayor tendencia a rumiar. Sin embargo, la mayoría de las mujeres contrarrestaron esta tendencia con una mayor capacidad para regular sus emociones a través de estrategias de reparación emocional anti-rumiación. Según los datos, esta capacidad parece conducir a una mayor disposición a comprender el punto de vista del nativo y, por tanto, posiblemente a una mayor disposición a integrarse en la sociedad de acogida., This article addresses the question as to why female migrants are more negatively affected than male migrants when confronted with unfamiliar traits in communication in the host country, but they are nevertheless more willing to adapt to the foreign style of communication. To answer this question, the different management of emotional regulation (Thayer et al. 2003) by both genders was investigated. A broad survey conducted among Spanish migrants in Germany led to the conclusion that the female migrants actually perceive the investigated traits more frequently and are also more affected by them. But, in comparison to the males, they have an increased ability to recognize and understand their emotions although they also display an increased tendency to ruminate. However, most of the women counteracted this tendency with a heightened ability to regulate their emotions through anti-rumination emotional repair strategies. According to the data, this ability seems to lead to a greater willingness to understand the views of the natives and thus possibly to being more disposed to integrate into the host society.

This "Data in brief" article was funded through Projects CGL2012-33281, CGL2012-32659, CGL2015-66835, and CGL2015-66830, Project RNM-05212 (Secretaria de Estado de I+D+I, Spain), Research Groups RNM-178 and RNM-179 (Junta de Andalucia) and FEDER funds. The research of Sosa-Montes de Oca was supported by a pre-doctoral fellowship from the Spanish Ministry, MINECO (BES-2013-064406)., A high-resolution analysis of the distribution of major and trace elements across the Cretaceous/Paleogene boundary (KPgB) in the distal section of Agost (SE Spain) was performed. The KPgB sediments were drilled to recover a 22 cm-long core; the lower 5 cm corresponding to the uppermost Maastrichtian and the upper 17 cm to the lowermost Danian. The unconsolidated sediments were resin-embedded under O2-free conditions, cut and polished. Laser Ablation-Inductivity Coupled Plasma-Mass Spectrometry (LA-ICP-MS) analyses were conducted at 10 µm increments and a laser-beam of 80 µm. Discrete samples were taken immediately prior to the resin-embedding and analyzed by Inductivity Coupled Plasma-Optical Emission Spectroscopy (ICP-OES). Results obtained by both analytical methods (LA-ICP-MS and ICP-OES) are presented. (Further interpretations and discussion are included in Sosa-Montes de Oca et al., 2018 [6])., Secretaria de Estado de I+D+I, Spain CGL2012-33281 CGL2012-32659 CGL2015-66835 CGL2015-66830 RNM-05212, Junta de Andalucia RNM-178 RNM-179, European Union (EU), Spanish Ministry, MINECO BES-2013-064406