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The following supporting information: Figure S1: HPLC chromatograms of betalains and phenolic compounds from Opuntia stricta var. dillenii green extracts. The numbers associated to the peaks are according to Table S1; Table S1: Characterization of the main betalains and phenolic compounds present in Opuntia stricta var. dillenii green extracts analyzed by HPLC-DAD and HPLC-MS1 [5]; Table S2: Composition of the digestive phases and the enzymes used for the in vitro gastro-intestinal digestion assay by INFOGEST method; Table S3. Recovery of main betalains and phenolic compounds from Opuntia stricta var. dillenii green extracts (control) encapsulated by Formulation A and Formulation B after in vitro gastro-intestinal digestion., Peer reviewed

Document S1. Supplemental Experimental Procedures, Figures S1–S7, and Table S1. Document S2. Article plus Supplemental Information., Peer reviewed

Experimental Procedures for Supplemental Figure: Double-stranded Zic2 and Zic2 mutant decoy DNA were prepared by annealing complementary single strands with the follow sequences: 5′-TCTTGGGTGGTCTCCGGAGACCACCCAAGA (for Zic2 decoy) and 5′-TCTTGAGTGAACTCCGGAGTTCACTCAAGA (for Zic2M decoy) as a negative control (Mizugishi et al., 2001). We utilized unlabeled and also Texas-red-tagged oligonucleotides (Invitrogen) to monitor DNA entry into cells. The terminal four bases on either site of the molecule were linked by phosphorothioate esters for added stability. Retinal explants were exposed to serial concentrations (0, 10, 100, and 200 μM) of decoy DNA combined with serial concentrations of serum-free medium (SFM) plus Fungene 6 transfection reagent (Roche) and incubated for 1 hr 30 min at 37°C. The explants were then washed several times in SFM, plated on D-polylysine/laminin, and incubated at 37°C, and dissociated chiasm cells were added to the cultures 2 hr later. They were then immunolabeled with α-neurofilament and explant outgrowth quantified, as indicated in Experimental Procedures., Figure S1. Zic2 Is Necessary for Ventrotemproal (VT) RGCs to Respond Negatively to Cues from the Chiasm Midline In Vitro. (A) Retinal explants grown on dissociated chiasm cells and immunostained with α-neurofilament. Representative images of dorsotemporal (DT) (a–d) and VT (e–h) retinal explants that were untransfected (a and e) or incubated with lipofectamine (b and f), Zic2 decoy oligos (c and g), or Zic2-mutant-decoy oligos (d and h) and subsequently cocultured with dissociated chiasm cells. Scale bar: 100 μm. (B) Quantification of area occupied by axons of DT (black columns) or VT (white columns) retinal explants that were untransfected or incubated with lipofectamine, Zic2-decoy oligos, or mutant-Zic2-decoy oligos, and then cocultured with dissociated chiasm cells. Left panels and graph: transfection of Zic2-decoy oligos does not affect the outgrowth in DT neurites (p > 0.2). Right panels and graph: transfection of Zic2-decoy oligos leads to increased growth of VT neurites. (*p < 0.05 compared with VT explants incubated with the lipofection agent alone or transfected with Zic2M-decoy). Number above bars indicates number of explants., Peer reviewed

Document S1. Supplemental Experimental Procedures, Figures S1–S4, and Table S1. Document S2. Article plus Supplemental Information., Peer reviewed

Functional maps of vestibular nerve stimulation evoked activity across imaging slices and statistical thresholds. This is a supplementary video to our Journal of Neuroscience paper linked below., Peer reviewed

Document S1. Supplemental Experimental Procedures, Figures S1–S5, and Tables S1–S3., Peer reviewed

7 pages. -- Fig. S1 Light microscopy image showing Gram-stained cells of strain MDTJ8T. The bar shows the scale of the image. -- Fig. S2. Scanning electron microscopy image of strain MDTJ8T. The bar shows the scale of the image. -- Fig. S3. Mobility test of strain MDTJ8T in a soft agar mRCM tube after 3 days of incubation. -- Fig. S4. Growth of strain MDTJ8T in PYG, fluid thioglycollate, and RCM media at pH 6.5±0.1 and 55°C. -- Fig. S5. Carbon utilization profile of strain MDTJ8T based on the AN MicroPlateTM from Biolog (Hayward, CA). -- Fig. S6. The polar lipids of strain MDTJ8T PL, phospholipid; GL, glycolipid; GPL, glucophospholipid; L, lipid. -- Table S1. List of proteins/enzymes putatively involving in synthesis of flagellum and sporulation in strain MDTJ8T as suggested by its genome annotation with Microscope. -- Table S2. Carbohydrate utilization of strain MDTJ8T and closely related members of the family Oscillospiraceae. -- Table S3. Comparison of non-carbohydrate substrate utilisation of strain MDTJ8T and closely related members of the family Oscillospiraceae, Peer reviewed

Supplementary Figures: Supplementary Figure 1. Short and long-term synaptic plasticity are preserved in the hippocampus of PD rats. (A) Pair pulse stimulation of the perforant pathway. Suprathreshold and equal intensity pairs of pulses (upper panel) are delivered at varying inter-stimulus time intervals (ISI). The results (lower panel) are expressed as the PS amplitude ratio (PS2/PS1). PS ratios below 1 indicate response depression and vice versa. Insets show pair pulse inhibition (left) and facilitation (right). (B) LTP of the perforant pathway. The upper panel shows the stimulation protocol used to induce LTP. Lower panel: synaptic potentiation in PD (orange) and control (black) rats quantified as the percentage increase of the PS amplitude after vs. before LTP induction. (C) Same as B but for the EPSP slope. (D) Evolution of the PS amplitude in response to perforant path stimulation before and 1 h after LTP induction. LTP protocol is applied at minute 6 (lasting 16 min) and PS amplitude is not tested until 1h later (grey shadow). The PS is normalized to pre-LTP measurements, and averaged across animals (n=5 per group). Data represents mean ± SEM. Supplementary Figure 2. Effect size of FA alterations in AUD patients analyzed with CSF correction (see Methods). Supplementary Figure 3. Effect size of FA alterations in a group of AUD patients chosen to avoid the age differences between groups. Supplementary Figure 4. Linear correlations between FA in the fimbria/fornix and cognitive variables: (A) NST, (B) TMT-A, (C) TMT-B, (D) number of perseverative errors in the WCST, (E) reaction times in the WCST, and (F) the Stroop test. (G) Correlation between FA in the fimbria/fornix and age. Supplementary Table 1. List of regions employed for the effect size analysis. Supplementary Table 2. List of cognitive test scores and age from AUD patients., Peer reviewed

Table of Contents: 1. NMR Spectra NMR spectra of 1-carbamoylmethyl-3-methoxiethyl-1H-imidazolim iodide (1a) NMR spectra of 1-carbamoylmethyl-3-methoxiethyl-1H-benzimidazolim iodide (1b) NMR spectra of 1-carbamoylmethyl-3-(2,6-diisopropylphenyl)-1H-imidazolim iodide (1c) NMR spectra of iridium complex 2a NMR spectra of iridium complex 2b In situ NMR spectra of iridium complex 2c NMR spectra of iridium complex 3c NMR spectra of iridium complex 4 NMR spectra of rhodium complex 5 NMR spectra of iridium complex 6 NMR spectra of iridium complex 7 2. IR spectra 3. General procedure for catalytic activity studies: Catalysis in HCOOH Catalysis in HCOOH/H2O (1:1 volume) Catalysis in HCOOH/Et3N (5:2 molar) 4. IR spectrum of the mixture of gases obtained from catalysis 5. Crystal structure of 1a, Peer reviewed

This is the auxiliary online material to the research article: Brands et al. (2023): A global climate model performance atlas for the Southern Hemisphere extratropics based on regional atmospheric circulation patterns For further informaion, please see the README.txt file contained herein or contact Swen Brands, swen.brands@gmail.com, Peer reviewed