Resultados totales (Incluyendo duplicados): 34416
Encontrada(s) 3442 página(s)
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311209
Dataset. 2022

NEUROPROTECTIVE POTENTIAL OF TERPENOID-RICH EXTRACTS FROM ORANGE JUICE BY-PRODUCTS OBTAINED BY PRESSURIZED LIQUID EXTRACTION: APPENDIX A. SUPPLEMENTARY DATA

  • Sánchez-Martínez, J. David
  • Álvarez-Rivera, Gerardo
  • Gallego, Rocío
  • Bittencourt Fagundes, Mariane
  • Valdés, Alberto
  • Mendiola, J. A.
  • Ibáñez, Elena
  • Cifuentes, Alejandro
Supplementary data 1., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311209
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311209
HANDLE: http://hdl.handle.net/10261/311209
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311209
PMID: http://hdl.handle.net/10261/311209
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311209
Ver en: http://hdl.handle.net/10261/311209
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311209

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311210
Dataset. 2022

EFFECTS OF MUTATIONS ON SAUR63:YFP:HA LOCALIZATION IN ROOT MERISTEM CELLS

  • Nagpal, Punita
  • Reeves, Paul H.
  • Wong, Jeh Haur
  • Armengot, Laia
  • Chae, Keun
  • Rieveschl, Nathaniel B.
  • Trinidad, Brendan
  • Davidsdottir, Vala
  • Jain, Prateek
  • Gray, William M.
  • Jaillais, Yvon
  • Reed, Jason W.
1 figure., A-D)P35S:SAUR63:YFP:HA. E-H)P35S:SAUR6326-142:YFP:HA. I-L)P35S:SAUR63m9:YFP:HA. M-P)P35S:SAUR63m13:YFP:HA. Q-T)P35S:SAUR63m15:YFP:HA. Shown are fluorescence confocal microscopy images of YFP (green, A,E,I,M,Q), FM4-64 membrane staining (magenta, B,F,J,N,R), and both channels together (C,G,K,O,S) with vertical yellow lines indicating locations of quantitation of fluorescence intensity signals, scaled to the maximum signal along the line (D,H,L,P,T). Image color channel brightnesses were adjusted for visibility. Panels A-D are the same as in Fig 8. Scale bar, 20 μm., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311210
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311210
HANDLE: http://hdl.handle.net/10261/311210
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311210
PMID: http://hdl.handle.net/10261/311210
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311210
Ver en: http://hdl.handle.net/10261/311210
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311210

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311213
Dataset. 2022

SUPPLEMENTARY MATERIALS FOR NEUROPROTECTIVE POTENTIAL OF THINNED PEACHES EXTRACTS OBTAINED BY PRESSURIZED LIQUID EXTRACTION AFTER DIFFERENT DRYING PROCESSES

  • Guo, Chongting
  • Valdés, Alberto
  • Sánchez-Martínez, J. David
  • Ibáñez, Elena
  • Bi, Jinfeng
  • Cifuentes, Alejandro
The supporting information: Table S1: Analysis of variance for TPC for response surface modeling showing linear, quadratic and interaction relations and coefficients for model prediction. Table S2: Analysis of variance for AChE for response surface modeling showing linear, quadratic and interaction relations and coefficients for model prediction. Table S3: Analysis of variance for LOX for response surface modeling showing linear, quadratic and interaction relations and coefficients for model prediction. Table S4: Analysis of variance for ROS for response surface modeling showing linear, quadratic and interaction relations and coefficients for model prediction. Table S5: PLE conditions, desirability, predicted response values at the optimum predicted by the model and experimental response values for the selected optimum (50% ethanol at 180 °C). Table S6: Multiple response optimization. Table S7: MS1 (m/z) and RT (min) of the internal standards used. Table S8: Abundance levels of tentatively identified metabolites in thinned peach PLE extracts. Figure S1: Response surfaces for each response variable and their corresponding standardized Pareto charts: A, TPC (mg GAE/mL); B, IC50 AChE (µg/mL); C, IC50 LOX (µg/mL); D, IC50 ROS (µg/mL). Figure S2: Desirability response surface used to optimize all response variables., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311213
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311213
HANDLE: http://hdl.handle.net/10261/311213
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311213
PMID: http://hdl.handle.net/10261/311213
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311213
Ver en: http://hdl.handle.net/10261/311213
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311213

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311215
Dataset. 2022

HYBRIDIZATION FUELLED DIVERSIFICATION IN SPIALIA BUTTERFLIES [DATASET]

  • Hinojosa, Joan Carles
  • Dapporto, Leonardo
  • Pitteloud, Camille
  • Koubínová, Darin
  • Hernández-Roldán, Juan L.
  • Vicente, Juan C.
  • Álvarez, Nadir
  • Vila, Roger
Here are published: The data sets used for the analyses and the most divergent loci between S. rosae and S. sertorius., PID2019-107078GB-I00/AEI/10.13039/501100011033 (Spanish Agencia Estatal de Investigación) 2017-SGR-991 (Generalitat de Catalunya) BES-2017–080641 (MINECO/AEI/FSE), Peer reviewed

DOI: http://hdl.handle.net/10261/311215
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311215
HANDLE: http://hdl.handle.net/10261/311215
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311215
PMID: http://hdl.handle.net/10261/311215
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311215
Ver en: http://hdl.handle.net/10261/311215
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311215

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311216
Dataset. 2022

SUPPORTING INFORMATION FOR PREBIOTIC POTENTIAL OF A NEW SWEETENER BASED ON GALACTOOLIGOSACCHARIDES AND MODIFIED MOGROSIDES

  • Muñoz Labrador, Ana
  • Lebrón-Aguilar, Rosa
  • Quintanilla-López, Jesús Eduardo
  • Galindo-Iranzo, Plácido
  • Azcarate, Silvana
  • Kolida, Sofía
  • Kachrimanidou, Vasiliki
  • García-Cañas, Virginia
  • Methven, Lisa
  • Rastall, Robert A.
  • Moreno, F. Javier
  • Hernández-Hernández, Oswaldo
Results of quantitative real-time PCR after in vitro fermentation at 10 and 24 h and statistical test data., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311216
HANDLE: http://hdl.handle.net/10261/311216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311216
PMID: http://hdl.handle.net/10261/311216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311216
Ver en: http://hdl.handle.net/10261/311216
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311216

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311222
Dataset. 2022

SUPPLEMENTARY MATERIALS FOR ROS SUPPRESSION BY EGG WHITE HYDROLYSATE IN DOCA-SALT RATS—AN ALTERNATIVE TOOL AGAINST VASCULAR DYSFUNCTION IN SEVERE HYPERTENSION

  • Luz Abreu, Edina da
  • Rodrigues Moro, Camila
  • Kanaan, Samia Hassan Husein
  • Bernardino de Paula, Ricardo
  • Teixeira Herrera, Camila
  • Dorneles Costa, Pedro Henrique
  • Peçanha, Franck Maciel
  • Vassallo, Dalton Valentim
  • Venturini Rossoni, Luciana
  • Miguel, Marta
  • Wiggers, Giulia Alessandra
The supporting information: Figure S1: The role of EWH in NF-κB-induced impairment on acetylcholine (ACh) relaxation in MRA of DOCA-salt rats; Figure S2: The role of EWH in NO-mediated acetylcholine (ACh)-induced relaxation in the aorta of DOCA-salt rats; Figure S3: NO production is recovered by EWH treatment in aortic sections of DOCA-salt rats., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311222
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311222
HANDLE: http://hdl.handle.net/10261/311222
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311222
PMID: http://hdl.handle.net/10261/311222
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311222
Ver en: http://hdl.handle.net/10261/311222
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311222

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311227
Dataset. 2022

SUPPLEMENTARY MATERIALS FOR SUPPLEMENTATION WITH THE SYMBIOTIC FORMULATION PRODEFEN® INCREASES NEURONAL NITRIC OXIDE SYNTHASE AND DECREASES OXIDATIVE STRESS IN SUPERIOR MESENTERIC ARTERY FROM SPONTANEOUSLY HYPERTENSIVE RATS

  • Méndez-Albiñana, Pablo
  • Martínez-González, Miguel Ángel
  • Camacho-Rodríguez, Laura
  • Ferreira-Lazarte, Alvaro
  • Villamiel, Mar
  • Rodrigues-Díez, Raquel
  • Balfagón, Gloria
  • García-Redondo, Ana B.
  • Prieto-Nieto, Mª Isabel
  • Blanco-Rivero, Javier
The supporting information: Figure S1: (a) Systolic blood pressure from WKY, SHR-Ctrl and SHR-SYNB animals (Mean + S.E.M.; n = 11–14 animals each group) expressed in mm Hg. One-way ANOVA, followed by a Tukey post-hoc test was used as a statistical analysis. * p < 0.05 WKY vs. SHR-Ctrl; # p < 0.05 SHR-Ctrl vs. SHR-SYNB. + p < 0.05 WKY vs. SHR-SYNB. (b) EFS-induced NO release in mesenteric segments from WKY, SHR-Ctrl and SHR-SYNB animals (Mean + S.E.M.; n = 11–14 animals each group) expressed in arbitrary fluorescence units (A.F.U.)/mg tissue. One-way ANOVA, followed by a Tukey post-hoc test was used as a statistical analysis. * p < 0.05 WKY vs. SHR-Ctrl; # p < 0.05 SHR-Ctrl vs. SHR-SYNB. + p < 0.05 WKY vs. SHR-SYNB (c) Analysis of the functional role of neuronal NO on EFS-induced vasoconstriction by preincubation with the unspecific nitric oxide synthase (NOS) inhibitor L-NAME, in mesenteric arteries WKY rats. Results (mean ± S.E.M.) are expressed as a percentage of previous tone induced by KCl. n = 6 segments from different animals in each ex-perimental group., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311227
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311227
HANDLE: http://hdl.handle.net/10261/311227
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311227
PMID: http://hdl.handle.net/10261/311227
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311227
Ver en: http://hdl.handle.net/10261/311227
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311227

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
Dataset. 2022

TABLE1_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.DOCX

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G.
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
HANDLE: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
PMID: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230
Ver en: http://hdl.handle.net/10261/311230
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311230

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
Dataset. 2022

SUPPLEMENTARY MATERIALS FOR UNDERSTANDING THE GASTROINTESTINAL BEHAVIOR OF THE COFFEE PULP PHENOLIC COMPOUNDS UNDER SIMULATED CONDITIONS

  • Cañas, Silvia
  • Rebollo-Hernanz, Miguel
  • Braojos, Cheyenne
  • Benitez, Vanesa
  • Ferreras-Charro, Rebeca
  • Dueñas, Montserrat
  • Aguilera, Yolanda
  • Martín-Cabrejas, María A.
The supporting information: Table S1: Retention index, bioaccessibility, and potential bioavailability (%) of phenolic families from coffee pulp flour (CPF) and extract (CPE) after in vitro digestion; Table S2: Physicochemical properties and intestinal absorption of the phenolic metabolites from the coffee pulp in silico colonic metabolism; Figure S1: Association between the molecular weight of the coffee pulp phenolic metabolites and their Caco-2 (A) and human intestinal (B) absorption., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
HANDLE: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
PMID: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236
Ver en: http://hdl.handle.net/10261/311236
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311236

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
Dataset. 2022

IMAGE5_EVOLUTIONARY TRAJECTORIES OF COMPLEX TRAITS IN EUROPEAN POPULATIONS OF MODERN HUMANS.JPEG

  • Kuijpers, Yunus
  • Domínguez-Andrés, Jorge
  • Bakker, Olivier B.
  • Gupta, Manoj Kumar
  • Grasshoff, Martin
  • Xu, Cheng-Jian
  • Joosten, Leo A. B.
  • Bertranpetit, Jaume
  • Netea, Mihai G
  • Li, Yang
Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors that influence human diseases. Here we built genome-wide polygenic scores for heritable traits, including height, body mass index, lipoprotein concentrations, cardiovascular disease, and intelligence, using summary statistics of genome-wide association studies in Europeans. Subsequently, we applied these scores to the genomes of ancient European populations. Our results revealed that after the Neolithic, European populations experienced an increase in height and intelligence scores, decreased their skin pigmentation, while the risk for coronary artery disease increased through a genetic trajectory favoring low HDL concentrations. These results are a reflection of the continuous evolutionary processes in humans and highlight the impact that the Neolithic revolution had on our lifestyle and health., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
HANDLE: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
PMID: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237
Ver en: http://hdl.handle.net/10261/311237
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311237

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