BUSCADOR RECOLECTA

Data regarding the MNP surface temperature estimation, magnetic measurements, and qPCR data for the HSP expression., Peer reviewed

This research was carried out with the financial assistance of the European Union under ENI CBC Mediterranean Sea Basin assistance of the European Union, through the project: Employing circular economy approach for OFMSW management within the Mediterranean countries. CEOMED (Ref.: A_B.4.2_0058). The contents of this document are the sole responsibility of CEBAS-CSIC and can under no circumstances be regarded as reflecting the position of the European Union or Programme management structures., Peer reviewed

3 files, Additional file 1. Remarks on the eSS optimisation solver and detailed results for the Goodwin Oscillator problem and additional ENSO contour plots. This file describes our modifications to the eSS global optimisation solver. It also contains tables and figures showing the detailed results for the Goodwin Oscillator problem, and additional contour plots for the ENSO example.-- Additional file 2. Critical comparison of optimisation solvers. In GEARS, the optimisation problems are solved using the hybrid metaheuristic eSS. A comparison of the eSS global optimisation solver used in GEARS with other competitive local and global optimisation solvers.-- Additional file 3. Detailed results for the Fitzhugh-Nagumo, Repressilator and Enzymatic Oscillator problems. This file contains tables and figures showing the detailed results for the Fitzhugh-Nagumo, Repressilator and Enzymatic Oscillator problems, Peer reviewed

Top: Injected current into the cell soma consisting of increasingly larger current steps interleaved by resting periods. The red line represents the identified rheobase. Middle: Cell model membrane voltage as a response to the injected current. The red line represents the voltage threshold in the model. Bottom: After-spike currents of the model. Sharp vertical lines indicate the presence of a spike., Peer reviewed

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(A) Left: Neuron’s membrane voltage response (top), input current response (middle), and firing rate (bottom) for a sample dVf neuron. The mean input current during visual flow (blue horizontal line) and the classification thresholds (black dots) are shown. Right: Responses of the different PSC sources for a sample dVf neuron, including total input current (red), recurrent current (olive), and LGN current (blue). Vertical dashed lines mark the visual flow period. (B) As in (A), but for a sample unclassified neuron. (C) As in (A), but for a sample hVf neuron., Peer reviewed

Peer reviewed

Peer reviewed

(A) Our findings suggest that TORC1 blocks Cbk1 kinase activity in the absence of Cdc15 function while cells are arrested in late anaphase at 37 °C, which would promote a defect in the following cell separation as secretory vesicle transporting hydrolases would be unable to fuse into the plasma membrane. (B) Rapamycin inhibits TORC1 and would induce the accumulation of a hypophosphorylated version of Cbk1 that would be able to phosphorylate its key substrates as the exocyct component Sec3, which regulates the function of the SNARE complex at the site of division to promote fusion of secretory vesicle at the plasma membrane. Hydrolases contained in secretory vesicle are released to promote cell separation., Peer reviewed

(A) Distribution of baseline input current mean for excitatory L2/3 classes (ANOVA: F = 162.8, p = 1.5 × 10−70, n = 12689; dVf vs hVf: t = 15.72, p = 1.5 × 10−54, n = 6311; dVf vs unc: t = 4.18, p = 2.9 × 10−5, n = 9326; hVf vs unc: t = 13.6, p = 2.8 × 10−41, n = 9741, Welch’s t test). (B) Distribution of baseline input current standard deviation (SD) for excitatory L2/3 classes (ANOVA: F = 14.96, p = 3.2 × 10−7, n = 12689; dVf vs hVf: t = 5.24, p = 1.7 × 10−7, n = 6311; dVf vs unc: t = 3.58, p = 3.5 × 10−4, n = 9326; hVf vs unc: t = 2.72, p = 0.0065, n = 9741, Welch’s t-test). Red triangles indicate the class mean., Peer reviewed