BUSCADOR RECOLECTA

Evolutionary history of the pharyngeal gene cluster with the full dataset., Peer reviewed

Positional analysis around Hox clusters based on unidirectional BLAST. The query species is shown in the middle of each panel. The curved lines connect gene pairs of the BLAST best hits. Hox genes are labeled in gray. Up to 20 neighboring genes of anterior and posterior Hox genes are shown and labeled in blue and red, respectively. Orthologous genes that are not located in chromosomes descended from DALGs E, B2, and C2 are omitted. The full list of BLAST comparisons is provided in S6 Data. The data underlying this figure can be found in S1 Data., Peer reviewed

[Introduction]: In monoclonal B cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL), the expansion of malignant B cells disrupts the normal homeostasis and interactions between B cells and T cells, leading to immune dysregulation. CD20+ T cells are a subpopulation of T cells that appear to be involved in autoimmune diseases and cancer., [Methods]: Here, we quantified and phenotypically characterized CD20+ T cells from MBL subjects and CLL patients using flow cytometry and correlated our findings with the B-cell receptor mutational status and other features of the disease., [Results and discussion]: CD20+ T cells were more represented within the CD8+ T cell compartment and they showed a predominant memory Tc1 phenotype. CD20+ T cells were less represented in MBL and CLL patients vs healthy controls, particularly among those with unmutated IGVH gene. The expansion of malignant B cells was accompanied by phenotypic and functional changes in CD20+ T cells, including an increase in follicular helper CD4+ CD20+ T cells and CD20+ Tc1 cells, in addition to the expansion of the TCR Vβ 5.1 in CD4+ CD20+ T cells in CLL., Peer reviewed

[Introduction]: In monoclonal B cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL), the expansion of malignant B cells disrupts the normal homeostasis and interactions between B cells and T cells, leading to immune dysregulation. CD20+ T cells are a subpopulation of T cells that appear to be involved in autoimmune diseases and cancer., [Methods]: Here, we quantified and phenotypically characterized CD20+ T cells from MBL subjects and CLL patients using flow cytometry and correlated our findings with the B-cell receptor mutational status and other features of the disease., [Results and discussion]: CD20+ T cells were more represented within the CD8+ T cell compartment and they showed a predominant memory Tc1 phenotype. CD20+ T cells were less represented in MBL and CLL patients vs healthy controls, particularly among those with unmutated IGVH gene. The expansion of malignant B cells was accompanied by phenotypic and functional changes in CD20+ T cells, including an increase in follicular helper CD4+ CD20+ T cells and CD20+ Tc1 cells, in addition to the expansion of the TCR Vβ 5.1 in CD4+ CD20+ T cells in CLL., Peer reviewed

15 pages, 3 tables, 7 figures, Supplementary Information for the article https://doi.org/10.1002/cssc.202301671, A. Biocarbon derived from fish waste preparation.-- B. Glycogen-based carbon characterization.-- C. Morphological characterization.-- D. Electrochemical characterization (3-electrode setup).-- E. Solid-state supercapacitor prototype assembly (Full cell setup).-- F. TiO2 samples characterization.-- G. TiO2-C composite samples characterization.-- H. References, Peer reviewed

Peer reviewed

Ministerio de Economía y Competitividad Instituto de Salud Carlos III, Peer reviewed

6 páginas, 5 tablas, 1 figura,, Peer reviewed

Experimental data published in the article "Metabolic rate of goldfish (Carassius auratus) in the face of common aquaculture challenges" in the journal "Biology2, Ministerio de Ciencia e Innovación, Peer reviewed

Peer reviewed