Resultados totales (Incluyendo duplicados): 35638
Encontrada(s) 3564 página(s)
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357945
Dataset. 2023

CCLE METABOLITE-PROTEOMICS CORRELATIONS FOR HMTS AND NNMT [DATASET]

  • Pérez, Marcos Francisco
  • Sarkies, Peter
CCLE metabolite-proteomics correlations for HMTs and NNMT., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/357945
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357945
HANDLE: http://hdl.handle.net/10261/357945
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357945
PMID: http://hdl.handle.net/10261/357945
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357945
Ver en: http://hdl.handle.net/10261/357945
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357945

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357931
Dataset. 2024

LIVE FUEL MOISTURE CONTENT ESTIMATES IN THE WESTERN USA USING RADIOMETER-RADAR-LIDAR SYNERGY

  • Chaparro, David
  • Jagdhuber, Thomas
  • Piles, María
  • Jonard, François
  • Fluhrer, Anke
  • Vall-llossera, Mercè
  • Camps, Adriano
  • López-Martínez, Carlos
  • Fernández-Morán, Roberto
  • Baur, Martín J.
  • Feldman, Andrew F.
  • Fink, Anita
  • Entekhabi, Dara
This dataset contains estimates of Live Fuel Moisture Content (LFMC) in the Western United States. LFMC is the percentage of vegetation water mass over the dry biomass of the plants. Here, LFMC is retrieved by isolating the water component of the passive microwaves vegetation optical depth (VOD) signal at three frequencies: L-band (1.4 GHz), X-band (10.65 GHz) and Ku-band (18.7 GHz). Each frequency represents a different canopy sensing depth. To isolate LFMC from VOD, auxiliary information to account for the biomass and structure of the vegetation has been used: radar backscatter data from Sentinel-1 and canopy height data from GEDI/Sentinel-2. The dataset spans between April 2015 and December 2018 for L- and X-bands, and between April 2015 and July 2018 for Ku-band retrievals., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/357931
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357931
HANDLE: http://hdl.handle.net/10261/357931
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357931
PMID: http://hdl.handle.net/10261/357931
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357931
Ver en: http://hdl.handle.net/10261/357931
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357931

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357933
Dataset. 2022

RECONSTRUCTED ANETO GLACIER SURFACES FROM HISTORIC AERIAL IMAGE PHOTOGRAMMETRY (1981) AND REMOTE SENSING TECHNIQUES (2020, 2021, 2022) [DATASET]

  • Vidaller, Ixeia
  • Izagirre, Eñaut
  • Rio, Luis Mariano del
  • Alonso-González, Esteban
  • Rojas-Heredia, Francisco
  • Serrano, Enrique
  • Moreno Caballud, Ana
  • López-Moreno, Juan I.
  • Revuelto, Jesús
The Aneto Glacier, is the largest glacier in the Pyrenees. Its shrinkage and wastage have been continuous in recent decades, and there are signs of accelerated melting in recent years. In this study, changes in the surface and ice thickness of the Aneto Glacier from 1981 to 2022 are investigated using historical aerial imagery, airborne LiDAR point clouds, and UAV imagery. A GPR survey conducted in 2020, combined with data from photogrammetric analyses, allowed us to reconstruct the current ice thickness and also the existing ice distribution in 1981 and 2011. Over the last 41 years, the total glaciated area has shrunk by 64.7% and the ice thickness has decreased, on average, by 30.5 m. The mean remaining ice thickness in autumn 2022 was 11.9 m, as against the mean thicknesses of 32.9 m, 19.2 m reconstructed for 1981 and 2011 and 15.0 m observed in 2020 respectively. The results demonstrate the critical situation of the glacier, with an imminent segmentation into two smaller ice bodies and no evidence of an accumulation zone. We also found that the occurrence of an extremely hot and dry year, as observed in the 2021–2022 season, leads to a drastic degradation of the glacier, posing a high risk to the persistence of the Aneto Glacier, a situation that could extend to the rest of the Pyrenean glaciers in a relatively short time., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/357933
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357933
HANDLE: http://hdl.handle.net/10261/357933
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357933
PMID: http://hdl.handle.net/10261/357933
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357933
Ver en: http://hdl.handle.net/10261/357933
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357933

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357952
Dataset. 2023

WIDESPREAD SPRING PHENOLOGY EFFECTS ON DROUGHT RECOVERY OF NORTHERN HEMISPHERE ECOSYSTEMS [DATASET]

  • Li, Yang
  • Zhang, Wen
  • Schwalm, Christopher R.
  • Gentine, Pierre
  • Smith, William K.
  • Ciais, Philippe
  • Kimball, John
  • Gazol Burgos, Antonio
  • Kannenberg, Steven A.
  • Chen, Anping
  • Piao, Shilong
  • Liu, Hongyan
  • Chen, Deliang
  • Wu, Xiuchen
PDF file contains: Supplementary Text; Supplementary Figures S1-S5; Supplementary Table S1., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/357952
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357952
HANDLE: http://hdl.handle.net/10261/357952
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357952
PMID: http://hdl.handle.net/10261/357952
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357952
Ver en: http://hdl.handle.net/10261/357952
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357952

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357962
Dataset. 2023

CCLE METABOLITE-RNA-SEQ CORRELATIONS FOR HMTS AND NNMT [DATASET]

  • Pérez, Marcos Francisco
  • Sarkies, Peter
CCLE metabolite-RNA-seq correlations for HMTs and NNMT., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/357962
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357962
HANDLE: http://hdl.handle.net/10261/357962
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357962
PMID: http://hdl.handle.net/10261/357962
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357962
Ver en: http://hdl.handle.net/10261/357962
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357962

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357979
Dataset. 2023

METHYLTRANSFERASE GENE SETS USED IN THIS STUDY [DATASET]

  • Pérez, Marcos Francisco
  • Sarkies, Peter
The N-terminal tails of eukaryotic histones are frequently posttranslationally modified. The role of these modifications in transcriptional regulation is well-documented. However, the extent to which the enzymatic processes of histone posttranslational modification might affect metabolic regulation is less clear. Here, we investigated how histone methylation might affect metabolism using metabolomics, proteomics, and RNA-seq data from cancer cell lines, primary tumour samples and healthy tissue samples. In cancer, the expression of histone methyltransferases (HMTs) was inversely correlated to the activity of NNMT, an enzyme previously characterised as a methyl sink that disposes of excess methyl groups carried by the universal methyl donor S-adenosyl methionine (SAM or AdoMet). In healthy tissues, histone methylation was inversely correlated to the levels of an alternative methyl sink, PEMT. These associations affected the levels of multiple histone marks on chromatin genome-wide but had no detectable impact on transcriptional regulation. We show that HMTs with a variety of different associations to transcription are co-regulated by the Retinoblastoma (Rb) tumour suppressor in human cells. Rb-mutant cancers show increased total HMT activity and down-regulation of NNMT. Together, our results suggest that the total activity of HMTs affects SAM metabolism, independent of transcriptional regulation., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/357979
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357979
HANDLE: http://hdl.handle.net/10261/357979
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357979
PMID: http://hdl.handle.net/10261/357979
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357979
Ver en: http://hdl.handle.net/10261/357979
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357979

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357988
Dataset. 2023

THE TRANSCRIPTIONAL REGULATOR GLYR1 MAY MEDIATE NNMT DOWN-REGULATION [DATASET]

  • Pérez, Marcos Francisco
  • Sarkies, Peter
The transcriptional regulator GLYR1 may mediate NNMT down-regulation., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/357988
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357988
HANDLE: http://hdl.handle.net/10261/357988
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357988
PMID: http://hdl.handle.net/10261/357988
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357988
Ver en: http://hdl.handle.net/10261/357988
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357988

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357999
Dataset. 2023

ALTERATION OF SAM/SAH RATIO TRANSCRIPTIONALLY REGULATES NNMT AND HMTS [DATASET]

  • Pérez, Marcos Francisco
  • Sarkies, Peter
Alteration of SAM/SAH ratio transcriptionally regulates Nnmt and HMTs., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/357999
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357999
HANDLE: http://hdl.handle.net/10261/357999
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357999
PMID: http://hdl.handle.net/10261/357999
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357999
Ver en: http://hdl.handle.net/10261/357999
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/357999

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/358013
Dataset. 2023

HISTONE METHYLTRANSFERASES ARE CO-EXPRESSED AND CORRELATE WITH NNMT/PEMT ORTHOLOGUES/ANALOGUES IN C. ELEGANS [DATASET]

  • Pérez, Marcos Francisco
  • Sarkies, Peter
Histone methyltransferases are co-expressed and correlate with NNMT/PEMT orthologues/analogues in C. elegans., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/358013
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/358013
HANDLE: http://hdl.handle.net/10261/358013
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/358013
PMID: http://hdl.handle.net/10261/358013
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/358013
Ver en: http://hdl.handle.net/10261/358013
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/358013

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/358017
Dataset. 2023

HIGHLY EXPRESSED HISTONE METHYLTRANSFERASE GENES ARE CO-EXPRESSED [DATASET]

  • Pérez, Marcos Francisco
  • Sarkies, Peter
Highly expressed histone methyltransferase genes are co-expressed., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/358017
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/358017
HANDLE: http://hdl.handle.net/10261/358017
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/358017
PMID: http://hdl.handle.net/10261/358017
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/358017
Ver en: http://hdl.handle.net/10261/358017
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/358017

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