Skip to main content
Set de datos (Dataset). 2025

Replication Data for: Functional analysis of two novel retinitis pigmentosa mutations reveals structural role of the third transmembrane helix in rhodopsin photoactivation

CORA.Repositori de Dades de Recerca
doi:10.34810/data2820
CORA.Repositori de Dades de Recerca
  • Fernandez, Pol
  • Cruz Saez, Alejandro
  • Wang, Feifei
  • Cordomí, Arnau
  • Morillo Cazorla, Margarita
  • Perez, Juan Jesus
  • Garriga, Pere
This dataset contains the AlphaFold3 (AF3) models of Rhodopsin (Rho) mutants T108P and G121R with highest AF3 score, topology and coordinates files of wild-type (WT) and T108P Rho to run their Molecular Dynamics (MD) simulations along with the necessary input files and the specific parameters for the Lysine-Retinal (LYR) residue, the MD representative structure of WT and T108P Rho and the computed channels that connect the LYR imine group with the bulk solvent for WT and T108P Rho.
 
DOI: https://doi.org/10.34810/data2820
CORA.Repositori de Dades de Recerca
doi:10.34810/data2820

HANDLE: https://doi.org/10.34810/data2820
CORA.Repositori de Dades de Recerca
doi:10.34810/data2820
 
Ver en: https://doi.org/10.34810/data2820
CORA.Repositori de Dades de Recerca
doi:10.34810/data2820
Volver atrás
×

1 Versiones

CORA.Repositori de Dades de Recerca
doi:10.34810/data2820
Set de datos (Dataset). 2025

REPLICATION DATA FOR: FUNCTIONAL ANALYSIS OF TWO NOVEL RETINITIS PIGMENTOSA MUTATIONS REVEALS STRUCTURAL ROLE OF THE THIRD TRANSMEMBRANE HELIX IN RHODOPSIN PHOTOACTIVATION

CORA.Repositori de Dades de Recerca
  • Fernandez, Pol
  • Cruz Saez, Alejandro
  • Wang, Feifei
  • Cordomí, Arnau
  • Morillo Cazorla, Margarita
  • Perez, Juan Jesus
  • Garriga, Pere
This dataset contains the AlphaFold3 (AF3) models of Rhodopsin (Rho) mutants T108P and G121R with highest AF3 score, topology and coordinates files of wild-type (WT) and T108P Rho to run their Molecular Dynamics (MD) simulations along with the necessary input files and the specific parameters for the Lysine-Retinal (LYR) residue, the MD representative structure of WT and T108P Rho and the computed channels that connect the LYR imine group with the bulk solvent for WT and T108P Rho.

DOI: https://doi.org/10.34810/data2820


×

1 Documentos relacionados

CORA.Repositori de Dades de Recerca
doi:10.34810/data2820
Set de datos (Dataset). 2025

REPLICATION DATA FOR: FUNCTIONAL ANALYSIS OF TWO NOVEL RETINITIS PIGMENTOSA MUTATIONS REVEALS STRUCTURAL ROLE OF THE THIRD TRANSMEMBRANE HELIX IN RHODOPSIN PHOTOACTIVATION

CORA.Repositori de Dades de Recerca
  • Fernandez, Pol
  • Cruz Saez, Alejandro
  • Wang, Feifei
  • Cordomí, Arnau
  • Morillo Cazorla, Margarita
  • Perez, Juan Jesus
  • Garriga, Pere
This dataset contains the AlphaFold3 (AF3) models of Rhodopsin (Rho) mutants T108P and G121R with highest AF3 score, topology and coordinates files of wild-type (WT) and T108P Rho to run their Molecular Dynamics (MD) simulations along with the necessary input files and the specific parameters for the Lysine-Retinal (LYR) residue, the MD representative structure of WT and T108P Rho and the computed channels that connect the LYR imine group with the bulk solvent for WT and T108P Rho.

DOI: https://doi.org/10.34810/data2820


Help guide