Set de datos (Dataset).
2024
Replication Data for "Citrate-assisted regulation of endocrine-like functions in bio-mimetic amyloids"
CORA.Repositori de Dades de Recerca
doi:10.34810/data1196
CORA.Repositori de Dades de Recerca
- de Pinho Favaro, Marianna T.
- López-Laguna, Hèctor
- Voltà-Durán, Eric
- Alba-Castellón, Lorena
- Sánchez, Julieta M.
- Casanova Rigat, Isolda
- Unzueta Elorza, Ugutz
- Mangues, Ramon
- Villaverde Corrales, Antonio
- Vázquez Gómez, Esther
Raw data of a set of experiments aimed to investigate the citrate-assisted regulation of endocrine-like functions in bio-mimetic amyloids.
Generic methodologies used here are similar to those described in:
- https://doi.org/10.1002/advs.201902420
- https://doi.org/10.1002/adfm.202100914
- https://doi.org/10.1080/10717544.2021.1998249
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40 Documentos relacionados
40 Documentos relacionados
Repositori Obert UdL
oai:repositori.udl.cat:10459.1/465844
Set de datos (Dataset). 2024
REPLICATION DATA FOR: FIRE IMPACTS ON THE BIOLOGY OF STREAM ECOSYSTEMS: A SYNTHESIS OF CURRENT KNOWLEDGE TO GUIDE FUTURE RESEARCH AND INTEGRATED FIRE MANAGEMENT
Repositori Obert UdL
- Erdozain Ibarra, Maitane
- Miguel Magaña, Sergio de
- Cardil Forradellas, Adrián
This dataset lists and summarizes all 161 articles that we used to write a review on the effects of fire on stream ecosystems. First we characterize each article in terms of country, biome, fire regime, stream size, stream slope, land use and cover, time since fire, study design, replication, indicators measured, etc. Then, we summarize the information extracted from the articles that measured biological stream endpoints and that we used to quantify and model the responses of different biological endpoints (namely benthic invertebrates, fish, periphyton and functional indicators) to fire.
CORA.Repositori de Dades de Recerca
doi:10.34810/data1119
Set de datos (Dataset). 2024
REPLICATION DATA FOR "ZINC-ASSISTED MICROSCALE GRANULES MADE OF THE SARS-COV-2 SPIKE PROTEIN TRIGGER NEUTRALIZING, ANTI-VIRUS ANTIBODY RESPONSES"
CORA.Repositori de Dades de Recerca
- Pinho Favaro, Marianna T.
- Álamo, Patricia
- Roher Armentia, Nerea
- Chillón Rodríguez, Miguel
- Lascorz Lozano, Jara A.
- Márquez, Mercè
- Corchero Nieto, José Luis
- Mendoza, Rosa
- Martínez-Torró, Carlos
- Ferrer-Miralles, Neus
- Ferreira, Luís
- Mangues, Ramon
- Vázquez Gómez, Esther
- Parladé Molist, Eloi
- Villaverde Corrales, Antonio
Set of data investigating the immunogenicity of SARS-CoV-2 spike protein.
CORA.Repositori de Dades de Recerca
doi:10.34810/data1196
Set de datos (Dataset). 2024
REPLICATION DATA FOR "CITRATE-ASSISTED REGULATION OF ENDOCRINE-LIKE FUNCTIONS IN BIO-MIMETIC AMYLOIDS"
CORA.Repositori de Dades de Recerca
- de Pinho Favaro, Marianna T.
- López-Laguna, Hèctor
- Voltà-Durán, Eric
- Alba-Castellón, Lorena
- Sánchez, Julieta M.
- Casanova Rigat, Isolda
- Unzueta Elorza, Ugutz
- Mangues, Ramon
- Villaverde Corrales, Antonio
- Vázquez Gómez, Esther
Raw data of a set of experiments aimed to investigate the citrate-assisted regulation of endocrine-like functions in bio-mimetic amyloids.
Generic methodologies used here are similar to those described in:
- https://doi.org/10.1002/advs.201902420
- https://doi.org/10.1002/adfm.202100914
- https://doi.org/10.1080/10717544.2021.1998249
CORA.Repositori de Dades de Recerca
doi:10.34810/data1273
Set de datos (Dataset). 2024
REPLICATION DATA FOR: "PEPTIDE-BASED BIOSENSING APPROACHES FOR TARGETING BREAST CANCER-DERIVED EXOSOMES"
CORA.Repositori de Dades de Recerca
- da Fonseca Alves
- Pallarès-Rusiñol, Arnau
- Rossi, Rosanna
- Martí, Mercè
- Rezende Vaz, Emilia
- Gonçalves de Araújo, Thaise
- Taboada Sotomayor, Maria Del Pilar
- Pividori, María Isabel
Exosomes are nanovesicles present in all the biological fluids, making them attractive as non-invasive biomarkers for diseases like cancer, among many others. However, exosomes are complex to separate and detect, requiring comprehensive molecular characterization for their routine use in diagnostics. This study explores the use of peptides as cost-effective and stable alternatives to antibodies for exosome binding. To achieve that, phage display technology was employed to select peptides with high specificity for target molecules in exosomes. Specifically, a selected peptide was evaluated for its ability to selectively bind breast cancer-derived exosomes. Proteomic analysis identified 38 protein candidates targeted by the peptide on exosome membranes. The binding of the peptide to breast cancer-derived exosomes was successfully demonstrated by flow cytometry and magneto-actuated immunoassays. Furthermore, an electrochemical biosensor was also tested for breast cancer-derived exosome detection and quantification. The peptide demonstrated effective binding to exosomes from aggressive cancer cell lines, offering promising results in terms of specificity and recovery. This research shows potential for developing rapid, accessible diagnostic tools for breast cancer, especially in low-resource healthcare settings.
CORA.Repositori de Dades de Recerca
doi:10.34810/data1314
Set de datos (Dataset). 2024
REPLICATION DATA FOR: "ENHANCING REPORTING THROUGH STRUCTURE: A BEFORE AND AFTER STUDY ON THE EFFECTIVENESS OF SPIRIT-BASED TEMPLATES TO IMPROVE THE COMPLETENESS OF REPORTING OF RANDOMIZED CONTROLLED TRIAL PROTOCOLS"
CORA.Repositori de Dades de Recerca
- Blanco de Tena Davila, David
This contains 3 datasets:
1) The study protocol approved by the Research Ethics Committee (CER) of the Universitat Internacional de Catalunya (Code: FIS-2022-11).
2) The outcome assessment form including the duplicate evaluation of the SPIRIT items.
3) The censored version (no temporal reference or participant personal data) of all RCT protocols included in the study.
CORA.Repositori de Dades de Recerca
doi:10.34810/data1388
Set de datos (Dataset). 2024
REPLICATION DATA FOR: FIRE IMPACTS ON THE BIOLOGY OF STREAM ECOSYSTEMS: A SYNTHESIS OF CURRENT KNOWLEDGE TO GUIDE FUTURE RESEARCH AND INTEGRATED FIRE MANAGEMENT
CORA.Repositori de Dades de Recerca
- Erdozain Ibarra, Maitane
- Miguel Magaña, Sergio de
- Cardil Forradellas, Adrián
This dataset lists and summarizes all 161 articles that we used to write a review on the effects of fire on stream ecosystems. First we characterize each article in terms of country, biome, fire regime, stream size, stream slope, land use and cover, time since fire, study design, replication, indicators measured, etc. Then, we summarize the information extracted from the articles that measured biological stream endpoints and that we used to quantify and model the responses of different biological endpoints (namely benthic invertebrates, fish, periphyton and functional indicators) to fire.
CORA.Repositori de Dades de Recerca
doi:10.34810/data1390
Set de datos (Dataset). 2024
REPLICATION DATA FOR "SEVERE DROUGHTS REDUCE RIVER NAVIGABILITY AND ISOLATE COMMUNITIES IN THE BRAZILIAN AMAZON"
CORA.Repositori de Dades de Recerca
- Santos De Lima, Leticia
- Silva, Francisco Eustáquio
- Anastácio, Paula Rosana Dorio
- Kolanski, Marina Marcela de Paula
- Pereira, Ana Carolina Pires
- Menezes, Marianne S. R.
- Cunha, Evandro Landulfo Teixeira Paradela
- Macedo, Marcia Nunes
This dataset encompasses data produced and analyzed in the context of the scientific article "Severe droughts reduce river navigability and isolate communities in the Brazilian Amazon" published at Communications Earth & Environment in 2024 (doi: 10.1038/s43247-024-01530-4). Three main analyses were performed for the article: (1) spatial analysis of accessibility of human settlements; (2) content analysis of media articles reporting impacts of severe droughts from 2000-2020, followed by temporal and spatial analysis; (3) hydrological analysis of water levels. The dataset includes: geospatial data, tabular data, and R scripts.
CORA.Repositori de Dades de Recerca
doi:10.34810/data1432
Set de datos (Dataset). 2024
REPLICATION DATA FOR "THE USE OF TEXT MESSAGES AS AN ALTERNATIVE INVITATION METHOD FOR BREAST CANCER SCREENING: A RANDOMIZED CONTROLLED TRIAL (M-TICS STUDY)"
CORA.Repositori de Dades de Recerca
- Vives, Núria
- Vidal, Carmen
- Niño de Guzmán, Ena Pery
- Farre, Albert
- Panera, Jon Aritz
- Binefa, Gemma
- Garcia, Mobtse
- M-TICS research group
This study aimed to determine whether a text message is as good as a postal letter as an invitation method for previous screenees in a breast cancer screening program, considering a non-inferiority margin of -2 percent points on participation rate. A non-inferiority randomized control trial was conducted. Women in the intervention group (n=5,362) were invited by text message, and women in the control group (n=5,482) were invited by letter, which is the standard invitation procedure of the program. In both groups, the invitation included a fixed appointment for mammography and a text message reminder 96 hours before the appointment. The primary outcome was screening participation rate (completing mammography within 12 weeks of invitation). The intention-to-treat analysis showed a participation rate of 87.3% and 86.6% in the control and intervention groups, respectively. The difference in participation rate was -0.7 percentage points (95% confidence interval [CI], -1.8 to ∞), indicating non-inferiority of text messages compared to letter invitations. The per-protocol analysis showed similar results.
In conclusion, we found that a text message invitation for women who had previously participated in breast cancer screening was not inferior to the standard letter.
CORA.Repositori de Dades de Recerca
doi:10.34810/data1481
Set de datos (Dataset). 2024
REPLICATION DATA FOR: EFFECTIVENESS AND ACCEPTABILITY OF TARGETED TEXT MESSAGE REMINDERS IN COLORECTAL CANCER SCREENING: A RANDOMISED CONTROLLED TRIAL (M-TICS STUDY)
CORA.Repositori de Dades de Recerca
- Vives, Núria
- Travier, Noemie
- Farre, Albert
- Binefa, Gemma
- Vidal, Carmen
- Pérez-Lacasta, Ma José
- Ibáñez-Sanz, Gemma
- Niño de Guzmán, Ena Pery
- Panera, Jon Aritz
- Garcia, Montse
Data from a randomized clinical trial aimed at evaluating the impact on participation of an additional FIT completion/return reminder delivered by text message to individuals who picked up but did not return their screening kit at pharmacy within 14 days in the colorectal screening program of the Metropolitan Area of Barcelona.
Setting: pharmacy-based screening program for colorectal cancer program in Catalonia, Spain.
Study population: 9,369 individuals aged 50-69 years invited to screening who picked up a FIT kit but did not return it within 14 days. Randomization into 2 groups: (1) Intervention (n=4,563): SMS reminder (on day 14 after picking it) + Reminder letter (if they had not completed the FIT 30 days after picking it up); (2) Control (n=4,806): Reminder letter (if they had not completed the FIT kit 30 days after picking it)
Main primary outcome: FIT completion rate within 30, 60, and 126 days from FIT kit pick-up (intention-to-treat-analysis).
Baseline variables included were sex, age group and tertiles of deprivation score index (DS), based on the individual's Catalan primary healthcare referral area.
CORA.Repositori de Dades de Recerca
doi:10.34810/data1552
Set de datos (Dataset). 2024
REPLICATION DATA FOR: "INVESTIGATING THE BIOCHEMICAL RESPONSE OF PROTON MINIBEAM RADIATION THERAPY BY MEANS OF SYNCHROTRON‑BASED INFRARED MICROSPECTROSCOPY"
CORA.Repositori de Dades de Recerca
- González-Vegas, Roberto
- Yousef, Ibraheem
- Seksek, Olivier
- Ortiz, Ramon
- Bertho, Annaïg
- Juchaux, Marjorie
- Nauraye, Catherine
- De Marzi, Ludovic
- Patriarca, Annalisa
- Prezado, Yolanda
- Martínez-Rovira, Immaculada
This dataset contains the infrared spectra of CTX-TNA2 rat astrocytes (healthy) and F98 rat glioma (tumour) cell lines subjected to standard proton radiotherapy and proton minibeam radiation therapy (pMBRT), measured via synchrotron radiation-based Fourier transform infrared microspectroscopy (SR-FTIRM).
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