Dataset.

Supporting information: Cellular receptors for mammalian viruses

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/360517
Digital.CSIC. Repositorio Institucional del CSIC
  • Valero-Rello, Ana
  • Baeza-Delgado, Carlos
  • Andreu-Moreno, Iván
  • Sanjuán, Rafael
S1 Fig. Workflow for the manual and automatic text-mining searches. A starting list of 6034 mammal viruses was used to obtain, which were then reviewed using both manual and PubmedKB-based automated strategies. The resulting virus-receptor pairs were combined with known databases and manually curated (see text for full description). M, manual strategy; PKB, PubmedKB strategy., S2 Fig. Roles of known receptors according to viral family. Only families with at least 10 known virus-host interactions are represented. Families of enveloped and non-enveloped viruses are shown, and within each group, families are sorted by the fraction of known receptors that are sufficient for viral entry (main plus alternative receptors)., S3 Fig. Research effort versus the known number of host proteins used as receptors for different viral families. Data points correspond to individual viruses. Those corresponding to the indicated family are shown in color (blue for non-enveloped viruses; yellow for enveloped viruses), and grey points correspond to all other viruses. The colored and grey dashed lines show the GLM prediction obtained specifically for the family and all viruses, respectively. Only families with at least 5 viral species in the dataset were considered., S1 Table. Database of virus receptors generated in this study. The following information is provided: the viral species, number of PubMed records and Genbank sequences available for each virus, viral family, presence of an envelope, number of host species, receptor symbol, receptor nature, functional role of the receptor, corresponding gene symbol, original publication PMID, year of discovery, and whether the virus-receptor interaction was reported in previous reviews and databases., S2 Table. Scores obtained from the GBM. The gene symbol, assigned score (probability of being a receptor), and whether the corresponding protein is a known receptor are indicated., S3 Table. Relevant features identified by the GBM. Gain represents the relative contribution of each variable to the model prediction. Cover indicates the relative number of observations that are related to a given variable., Peer reviewed
 
DOI: http://hdl.handle.net/10261/360517
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/360517

HANDLE: http://hdl.handle.net/10261/360517
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/360517
 
Ver en: http://hdl.handle.net/10261/360517
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/360517

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/360517
Dataset. 2024

SUPPORTING INFORMATION: CELLULAR RECEPTORS FOR MAMMALIAN VIRUSES

Digital.CSIC. Repositorio Institucional del CSIC
  • Valero-Rello, Ana
  • Baeza-Delgado, Carlos
  • Andreu-Moreno, Iván
  • Sanjuán, Rafael
S1 Fig. Workflow for the manual and automatic text-mining searches. A starting list of 6034 mammal viruses was used to obtain, which were then reviewed using both manual and PubmedKB-based automated strategies. The resulting virus-receptor pairs were combined with known databases and manually curated (see text for full description). M, manual strategy; PKB, PubmedKB strategy., S2 Fig. Roles of known receptors according to viral family. Only families with at least 10 known virus-host interactions are represented. Families of enveloped and non-enveloped viruses are shown, and within each group, families are sorted by the fraction of known receptors that are sufficient for viral entry (main plus alternative receptors)., S3 Fig. Research effort versus the known number of host proteins used as receptors for different viral families. Data points correspond to individual viruses. Those corresponding to the indicated family are shown in color (blue for non-enveloped viruses; yellow for enveloped viruses), and grey points correspond to all other viruses. The colored and grey dashed lines show the GLM prediction obtained specifically for the family and all viruses, respectively. Only families with at least 5 viral species in the dataset were considered., S1 Table. Database of virus receptors generated in this study. The following information is provided: the viral species, number of PubMed records and Genbank sequences available for each virus, viral family, presence of an envelope, number of host species, receptor symbol, receptor nature, functional role of the receptor, corresponding gene symbol, original publication PMID, year of discovery, and whether the virus-receptor interaction was reported in previous reviews and databases., S2 Table. Scores obtained from the GBM. The gene symbol, assigned score (probability of being a receptor), and whether the corresponding protein is a known receptor are indicated., S3 Table. Relevant features identified by the GBM. Gain represents the relative contribution of each variable to the model prediction. Cover indicates the relative number of observations that are related to a given variable., Peer reviewed




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