Dataset.

Supporting Information for Adv. Healthcare Mater., DOI 10.1002/adhm.202201968 Graphene Oxide Nanoscale Platform Enhances the Anti-Cancer Properties of Bortezomib in Glioblastoma Models

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/336931
Digital.CSIC. Repositorio Institucional del CSIC
  • Sharp, Paul S.
  • Stylianou, Maria
  • Arellano, Luis M.
  • Neves, Juliana C.
  • Gravagnuolo, Alfredo M.
  • Dodd, Abbie
  • Barr, Katharine
  • Lozano, Neus
  • Kisby, Thomas
  • Kostarelos, Kostas
13 pages. -- Supplementary Experimental: Supplementary physicochemical characterization of GO and GO:BTZ complex. -- Image analysis and classification. -- Figure S1. Non-covalent GO:BTZ complex formation and determination of BTZ loaded in complex. -- Figure S2. BTZ release profile in water from GO:BTZ complex measured by UV-vis after 0h, 4h or 24h in water. -- Figure S3. Physicochemical characterization of GOc and GO:BTZ complex. -- Figure S4. GO and GO:BTZ nanosheet suspension characteristics in serum (10% FBS) for 24hrs. -- Figure S5. GO-BTZ forms a necrotic zone extending from the GO injection site. -- Figure S6. Kinetics of GO:BTZ induced necrosis with direct comparison to free BTZ. -- Figure S7. Characterisation of the U87 and GL261 tumor models. -- Figure S8. GO-BTZ forming a significant necrotic core within the injected tumor area. -- Figure S9. Representative Orbit image classification. -- Figure S10. Longitudinal assessment of treatment effect and biosafety. -- Table S1: Physicochemical properties of GO sheets including lateral dimension, thickness, optical properties, surface charge and chemical composition., Peer reviewed
 
DOI: http://hdl.handle.net/10261/336931
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/336931

HANDLE: http://hdl.handle.net/10261/336931
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/336931
 
Ver en: http://hdl.handle.net/10261/336931
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/336931

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/336931
Dataset. 2023

SUPPORTING INFORMATION FOR ADV. HEALTHCARE MATER., DOI 10.1002/ADHM.202201968 GRAPHENE OXIDE NANOSCALE PLATFORM ENHANCES THE ANTI-CANCER PROPERTIES OF BORTEZOMIB IN GLIOBLASTOMA MODELS

Digital.CSIC. Repositorio Institucional del CSIC
  • Sharp, Paul S.
  • Stylianou, Maria
  • Arellano, Luis M.
  • Neves, Juliana C.
  • Gravagnuolo, Alfredo M.
  • Dodd, Abbie
  • Barr, Katharine
  • Lozano, Neus
  • Kisby, Thomas
  • Kostarelos, Kostas
13 pages. -- Supplementary Experimental: Supplementary physicochemical characterization of GO and GO:BTZ complex. -- Image analysis and classification. -- Figure S1. Non-covalent GO:BTZ complex formation and determination of BTZ loaded in complex. -- Figure S2. BTZ release profile in water from GO:BTZ complex measured by UV-vis after 0h, 4h or 24h in water. -- Figure S3. Physicochemical characterization of GOc and GO:BTZ complex. -- Figure S4. GO and GO:BTZ nanosheet suspension characteristics in serum (10% FBS) for 24hrs. -- Figure S5. GO-BTZ forms a necrotic zone extending from the GO injection site. -- Figure S6. Kinetics of GO:BTZ induced necrosis with direct comparison to free BTZ. -- Figure S7. Characterisation of the U87 and GL261 tumor models. -- Figure S8. GO-BTZ forming a significant necrotic core within the injected tumor area. -- Figure S9. Representative Orbit image classification. -- Figure S10. Longitudinal assessment of treatment effect and biosafety. -- Table S1: Physicochemical properties of GO sheets including lateral dimension, thickness, optical properties, surface charge and chemical composition., Peer reviewed




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