Dataset.

Additional file 1 of An amino acid transporter subunit as an antibody–drug conjugate target in colorectal cancer [Dataset]

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/360647
Digital.CSIC. Repositorio Institucional del CSIC
  • Montero, Juan Carlos
  • Carmen, Sofía del
  • Abad, Mar
  • Sayagués, José María
  • Barbáchano, Antonio
  • Fernández-Barral, Asunción
  • Muñoz Terol, Alberto
  • Pandiella, Atanasio
Additional file 1: Supplementary Fig. 1. A) Box plot showing SLC3A2 gene expression levels in paired normal colon tissue and tumoral CRC tissue, using TNMplot online tool. FC = fold change. P value obtained using Mann Whitney U test. B) Box plot showing SLC3A2 gene expression levels in normal colon tissue and tumoral CRC tissue samples. Data were obtained from the GEPIA2. P value obtained using one-way ANOVA test. C) Box plot showing SLC3A2 gene expression levels in normal colon tissue and tumoral CRC tissue normal, using TNMplot online tool. P value obtained using Mann Whitney U test. D) Box plot showing the CD98hc score analyzed by immunohistochemistry in primary tumor, lymph node and liver metastases. P values were obtained using Student t test (two-sided). E) Immunohistochemical staining of CD98hc in representative samples from the study shown in D, assessed using with anti-CD98hcV509 antibody. Magnification: 40X. F) Box plot showing SLC3A2 gene expression levels in tumor and metastatic tissue of CRC patients. T = tumor, N = normal and M = metastatic. P value obtained using Kruskal–Wallis test. G) Heatmap (top) and boxplot (bottom) representative of the expression of CD98hc in different normal and tumoral tissues, obtained from the TNMplot database. Tissues written in red represent significant differences by the Mann–Whitney test. H) Expression of CD98hc in different normal and tumoral tissues. Data obtained from the GENT2 database., Instituto de Salud Carlos III Consejo Superior de Investigaciones Científicas Junta de Castilla y León ALMOM ACMUMA UCCTA CRIS Cancer Foundation Agencia Estatal de Investigación Consejo Superior de Investigaciones Cientificas (CSIC), Peer reviewed
 
DOI: http://hdl.handle.net/10261/360647
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/360647

HANDLE: http://hdl.handle.net/10261/360647
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/360647
 
Ver en: http://hdl.handle.net/10261/360647
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/360647

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/360647
Dataset. 2023

ADDITIONAL FILE 1 OF AN AMINO ACID TRANSPORTER SUBUNIT AS AN ANTIBODY–DRUG CONJUGATE TARGET IN COLORECTAL CANCER [DATASET]

Digital.CSIC. Repositorio Institucional del CSIC
  • Montero, Juan Carlos
  • Carmen, Sofía del
  • Abad, Mar
  • Sayagués, José María
  • Barbáchano, Antonio
  • Fernández-Barral, Asunción
  • Muñoz Terol, Alberto
  • Pandiella, Atanasio
Additional file 1: Supplementary Fig. 1. A) Box plot showing SLC3A2 gene expression levels in paired normal colon tissue and tumoral CRC tissue, using TNMplot online tool. FC = fold change. P value obtained using Mann Whitney U test. B) Box plot showing SLC3A2 gene expression levels in normal colon tissue and tumoral CRC tissue samples. Data were obtained from the GEPIA2. P value obtained using one-way ANOVA test. C) Box plot showing SLC3A2 gene expression levels in normal colon tissue and tumoral CRC tissue normal, using TNMplot online tool. P value obtained using Mann Whitney U test. D) Box plot showing the CD98hc score analyzed by immunohistochemistry in primary tumor, lymph node and liver metastases. P values were obtained using Student t test (two-sided). E) Immunohistochemical staining of CD98hc in representative samples from the study shown in D, assessed using with anti-CD98hcV509 antibody. Magnification: 40X. F) Box plot showing SLC3A2 gene expression levels in tumor and metastatic tissue of CRC patients. T = tumor, N = normal and M = metastatic. P value obtained using Kruskal–Wallis test. G) Heatmap (top) and boxplot (bottom) representative of the expression of CD98hc in different normal and tumoral tissues, obtained from the TNMplot database. Tissues written in red represent significant differences by the Mann–Whitney test. H) Expression of CD98hc in different normal and tumoral tissues. Data obtained from the GENT2 database., Instituto de Salud Carlos III Consejo Superior de Investigaciones Científicas Junta de Castilla y León ALMOM ACMUMA UCCTA CRIS Cancer Foundation Agencia Estatal de Investigación Consejo Superior de Investigaciones Cientificas (CSIC), Peer reviewed




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