Dataset.

Supplementary Materials for A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/359207
Digital.CSIC. Repositorio Institucional del CSIC
  • Burn Aschner, Clare
  • Muthuraman, Krithika
  • Kucharska, Iga
  • Cui, Hong
  • Prieto, Katherine
  • Nair, Manoj S.
  • Wang, Maple
  • Huang, Yaoxing
  • Christie-Holmes, Natasha
  • Poon, Betty
  • Lam, Jessica
  • Sultana, Azmiri
  • Kozak, Robert
  • Mubareka, Samira
  • Rubinstein, John L.
  • Rujas, Edurne
  • Treanor, Bebhinn
  • Ho, David D.
  • Jetha, Arif
  • Julien, Jean-Philippe
All data associated with this study are present in the paper or the Supplementary Materials. The electron microscopy maps have been deposited in the Electron Microscopy Data Bank (EMDB) with accession codes EMD-28067 (tri-specific MB, refinement with no symmetry) and EMD-28068 (tri-specific MB, octahedral symmetry). The crystal structure of 80 Fab–RBD has been deposited in the Protein Data Bank (PDB ID: 8DNN). Materials will be made available to the scientific community by contacting the corresponding author and completion of a materials transfer agreement. This work is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. This license does not apply to figures/photos/artwork or other content included in the article that is credited to a third party; obtain authorization from the rights holder before using this material., The PDF file includes: Supplementary Materials and Methods Figs. S1 to S10 Tables S1 to S3 Legend for data file S1 References (72–92) Other Supplementary Material for this manuscript includes the following: Data file S1 MDAR Reproducibility Checklist, Peer reviewed
 
DOI: http://hdl.handle.net/10261/359207
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/359207

HANDLE: http://hdl.handle.net/10261/359207
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/359207
 
Ver en: http://hdl.handle.net/10261/359207
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/359207

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/359207
Dataset. 2023

SUPPLEMENTARY MATERIALS FOR A MULTI-SPECIFIC, MULTI-AFFINITY ANTIBODY PLATFORM NEUTRALIZES SARBECOVIRUSES AND CONFERS PROTECTION AGAINST SARS-COV-2 IN VIVO

Digital.CSIC. Repositorio Institucional del CSIC
  • Burn Aschner, Clare
  • Muthuraman, Krithika
  • Kucharska, Iga
  • Cui, Hong
  • Prieto, Katherine
  • Nair, Manoj S.
  • Wang, Maple
  • Huang, Yaoxing
  • Christie-Holmes, Natasha
  • Poon, Betty
  • Lam, Jessica
  • Sultana, Azmiri
  • Kozak, Robert
  • Mubareka, Samira
  • Rubinstein, John L.
  • Rujas, Edurne
  • Treanor, Bebhinn
  • Ho, David D.
  • Jetha, Arif
  • Julien, Jean-Philippe
All data associated with this study are present in the paper or the Supplementary Materials. The electron microscopy maps have been deposited in the Electron Microscopy Data Bank (EMDB) with accession codes EMD-28067 (tri-specific MB, refinement with no symmetry) and EMD-28068 (tri-specific MB, octahedral symmetry). The crystal structure of 80 Fab–RBD has been deposited in the Protein Data Bank (PDB ID: 8DNN). Materials will be made available to the scientific community by contacting the corresponding author and completion of a materials transfer agreement. This work is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. This license does not apply to figures/photos/artwork or other content included in the article that is credited to a third party; obtain authorization from the rights holder before using this material., The PDF file includes: Supplementary Materials and Methods Figs. S1 to S10 Tables S1 to S3 Legend for data file S1 References (72–92) Other Supplementary Material for this manuscript includes the following: Data file S1 MDAR Reproducibility Checklist, Peer reviewed




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