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Supplementary information. ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/337537
Digital.CSIC. Repositorio Institucional del CSIC
  • Mensali, Nadia
  • Köksal, Hakan
  • Joaquina, Sandy
  • Wernhoff, Patrik
  • Casey, Nicholas P.
  • Romecin, Paola
  • Panisello, Carla
  • Rodriguez, René
  • Vimeux, Lene
  • Juzeniene, Asta
  • Myhre, Marit R.
  • Fåne, Anne
  • Castilla, Carolina
  • Maggadottir, Solrun Melkorka
  • Duru, Adil Doganay
  • Georgoudaki, Anna-Maria
  • Grad, Iwona
  • Maturana, Andrés Daniel
  • Gaudernack, Gustav
  • Kvalheim, Gunnar
  • Carcaboso, Ángel M.
  • Álava, Enrique de
  • Donnadieu, Emmanuel
  • Bruland, Øyvind S.
  • Menéndez, Pablo
  • Inderberg, Else Marit
  • Wälchli, Sébastien
Supplementary Figure 1. TP antibody specificity and affinity. a.-- Supplementary Figure 2. a, Proliferation capability of OSCAR T cells upon rechallenge with OHS cell line.-- Supplementary Figure 3. In vitro effector function of OSCAR -1 and OSCAR -3 T cells towards LM7 OS cells. a.-- Supplementary Figure 4. In vivo effector function of OSCAR-1 and OSCAR-3 T cells in lung metastatic mouse models. a.-- Supplementary Figure. 5 Staining of target cells in figure 5b with anti ALPL, TP-1 and TP-3 antibodies. Isotype and secondary antibody controls (grey).-- Supplementary methods., Peer reviewed
 
DOI: http://hdl.handle.net/10261/337537
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/337537

HANDLE: http://hdl.handle.net/10261/337537
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/337537
 
Ver en: http://hdl.handle.net/10261/337537
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/337537

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/337537
Set de datos (Dataset). 2023

SUPPLEMENTARY INFORMATION. ALPL-1 IS A TARGET FOR CHIMERIC ANTIGEN RECEPTOR THERAPY IN OSTEOSARCOMA

Digital.CSIC. Repositorio Institucional del CSIC
  • Mensali, Nadia
  • Köksal, Hakan
  • Joaquina, Sandy
  • Wernhoff, Patrik
  • Casey, Nicholas P.
  • Romecin, Paola
  • Panisello, Carla
  • Rodriguez, René
  • Vimeux, Lene
  • Juzeniene, Asta
  • Myhre, Marit R.
  • Fåne, Anne
  • Castilla, Carolina
  • Maggadottir, Solrun Melkorka
  • Duru, Adil Doganay
  • Georgoudaki, Anna-Maria
  • Grad, Iwona
  • Maturana, Andrés Daniel
  • Gaudernack, Gustav
  • Kvalheim, Gunnar
  • Carcaboso, Ángel M.
  • Álava, Enrique de
  • Donnadieu, Emmanuel
  • Bruland, Øyvind S.
  • Menéndez, Pablo
  • Inderberg, Else Marit
  • Wälchli, Sébastien
Supplementary Figure 1. TP antibody specificity and affinity. a.-- Supplementary Figure 2. a, Proliferation capability of OSCAR T cells upon rechallenge with OHS cell line.-- Supplementary Figure 3. In vitro effector function of OSCAR -1 and OSCAR -3 T cells towards LM7 OS cells. a.-- Supplementary Figure 4. In vivo effector function of OSCAR-1 and OSCAR-3 T cells in lung metastatic mouse models. a.-- Supplementary Figure. 5 Staining of target cells in figure 5b with anti ALPL, TP-1 and TP-3 antibodies. Isotype and secondary antibody controls (grey).-- Supplementary methods., Peer reviewed




Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/337537
Set de datos (Dataset). 2023

SUPPLEMENTARY INFORMATION. ALPL-1 IS A TARGET FOR CHIMERIC ANTIGEN RECEPTOR THERAPY IN OSTEOSARCOMA

Digital.CSIC. Repositorio Institucional del CSIC
  • Mensali, Nadia
  • Köksal, Hakan
  • Joaquina, Sandy
  • Wernhoff, Patrik
  • Casey, Nicholas P.
  • Romecin, Paola
  • Panisello, Carla
  • Rodriguez, René
  • Vimeux, Lene
  • Juzeniene, Asta
  • Myhre, Marit R.
  • Fåne, Anne
  • Castilla, Carolina
  • Maggadottir, Solrun Melkorka
  • Duru, Adil Doganay
  • Georgoudaki, Anna-Maria
  • Grad, Iwona
  • Maturana, Andrés Daniel
  • Gaudernack, Gustav
  • Kvalheim, Gunnar
  • Carcaboso, Ángel M.
  • Álava, Enrique de
  • Donnadieu, Emmanuel
  • Bruland, Øyvind S.
  • Menéndez, Pablo
  • Inderberg, Else Marit
  • Wälchli, Sébastien
Supplementary Figure 1. TP antibody specificity and affinity. a.-- Supplementary Figure 2. a, Proliferation capability of OSCAR T cells upon rechallenge with OHS cell line.-- Supplementary Figure 3. In vitro effector function of OSCAR -1 and OSCAR -3 T cells towards LM7 OS cells. a.-- Supplementary Figure 4. In vivo effector function of OSCAR-1 and OSCAR-3 T cells in lung metastatic mouse models. a.-- Supplementary Figure. 5 Staining of target cells in figure 5b with anti ALPL, TP-1 and TP-3 antibodies. Isotype and secondary antibody controls (grey).-- Supplementary methods., Peer reviewed




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