Dataset.

Additional file 3 of Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia [Dataset]

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/329849
Digital.CSIC. Repositorio Institucional del CSIC
  • Hortal, Alejandro
  • Oeste, Clara L.
  • Cifuentes, Claudia
  • Alcoceba, Miguel
  • Fernández-Pisonero, Isabel
  • Clavaín, Laura
  • Tercero, Rut
  • Mendoza, Pilar
  • Domínguez, Verónica
  • García-Flores, Marta
  • Pintado, Belén
  • Abia, David
  • García-Macías, Carmen
  • Navarro-Bailón, Almudena
  • Bustelo, Xosé R.
  • González, Marcos
  • Alarcón, Balbino
Additional file 3: Figure S3. a, Representative two-color contour plots of B cell populations in a peritoneal wash and the spleen of 12 wk-old mice according to the expression of the CD11b and CD5 markers in the CD19+ population. The blue square indicates CD11b + CD5- B1b cells in the peritoneum. Red square, the presence of CD11b + CD5+ B1a cells in control mice and leukemic cells. Quantification of CD11b + CD5+ cells is shown to the right in box and whiskers plots showing all points and median value. **p < 0.01; *** p < 0.001, two-tailed unpaired t-test with Welch’s correction. b, Representative two-color contour plots of IgM and GFP expression within the CD11b + CD5+ populations shown in a. Quantification of IgMbright cells within the CD11b + CD5+ B cell population is shown to the right in box and whiskers plots showing all points and median value. **** p < 0.0001, two-tailed unpaired t-test with Welch’s correction., Fundación Científica Asociación Española Contra el Cáncer Ministerio de Ciencia, Innovación y Universidades H2020 European Research Council Instituto de Salud Carlos III Consejería de Educación, Junta de Castilla y León, Peer reviewed
 
DOI: http://hdl.handle.net/10261/329849
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/329849

HANDLE: http://hdl.handle.net/10261/329849
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/329849
 
Ver en: http://hdl.handle.net/10261/329849
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/329849

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/329849
Dataset. 2022

ADDITIONAL FILE 3 OF OVEREXPRESSION OF WILD TYPE RRAS2, WITHOUT ONCOGENIC MUTATIONS, DRIVES CHRONIC LYMPHOCYTIC LEUKEMIA [DATASET]

Digital.CSIC. Repositorio Institucional del CSIC
  • Hortal, Alejandro
  • Oeste, Clara L.
  • Cifuentes, Claudia
  • Alcoceba, Miguel
  • Fernández-Pisonero, Isabel
  • Clavaín, Laura
  • Tercero, Rut
  • Mendoza, Pilar
  • Domínguez, Verónica
  • García-Flores, Marta
  • Pintado, Belén
  • Abia, David
  • García-Macías, Carmen
  • Navarro-Bailón, Almudena
  • Bustelo, Xosé R.
  • González, Marcos
  • Alarcón, Balbino
Additional file 3: Figure S3. a, Representative two-color contour plots of B cell populations in a peritoneal wash and the spleen of 12 wk-old mice according to the expression of the CD11b and CD5 markers in the CD19+ population. The blue square indicates CD11b + CD5- B1b cells in the peritoneum. Red square, the presence of CD11b + CD5+ B1a cells in control mice and leukemic cells. Quantification of CD11b + CD5+ cells is shown to the right in box and whiskers plots showing all points and median value. **p < 0.01; *** p < 0.001, two-tailed unpaired t-test with Welch’s correction. b, Representative two-color contour plots of IgM and GFP expression within the CD11b + CD5+ populations shown in a. Quantification of IgMbright cells within the CD11b + CD5+ B cell population is shown to the right in box and whiskers plots showing all points and median value. **** p < 0.0001, two-tailed unpaired t-test with Welch’s correction., Fundación Científica Asociación Española Contra el Cáncer Ministerio de Ciencia, Innovación y Universidades H2020 European Research Council Instituto de Salud Carlos III Consejería de Educación, Junta de Castilla y León, Peer reviewed




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