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Publicación Artículo científico (article).

Cyclooxygenase 2 in liver dysfunction and carcinogenesis: Facts and perspectives

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/155392
Digital.CSIC. Repositorio Institucional del CSIC
  • Martín-Sanz, Paloma
  • Casado, Marta
  • Boscá, Lisardo
The biosynthesis of prostaglandins and thromboxanes has been a focus of interest in the management of many liver diseases. Cyclooxygenases are the enzymes involved in the first step of the biosynthesis of these lipid mediators and selective inhibitors for these isoenzymes as well as pharmacological analogues of prostaglandins have been developed and are currently applied therapeutically. Here we discuss the implications of these enzymes in the onset of metabolic and lipid disorders in the liver and their potential role in the progression of the diseases towards fibrosis and hepatocellular carcinogenesis., Supported by MINECO, Spain, No. SAF2014-52492R; COOPB20213 (CSIC), No. SAF2013-43713R and No. SAF2016-75004R; ISCIII, Spain, CIBERcv and CIBERehd; We thank FEDER for financial support., Peer reviewed
 
Proyecto: MINECO, MINECO, MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016, Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016, Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2014-52492R, SAF2013-43713R, SAF2016-75004R

DOI: http://hdl.handle.net/10261/155392
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/155392

HANDLE: http://hdl.handle.net/10261/155392
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/155392
 
Ver en: http://hdl.handle.net/10261/155392
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/155392
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