Dataset.

Supplementary Materials: In silico exploration of Mycobacterium tuberculosis metabolic networks shows host-associated convergent fluxomic phenotypes

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/330900
Digital.CSIC. Repositorio Institucional del CSIC
  • Santamaria, Guillem
  • Ruiz-Rodríguez, Paula
  • Renau-Mínguez, Chantal
  • Pinto, Francisco R.
  • Coscollá, Mireia
Figure S1: Correspondence Analysis of all the potentially deleterious SNPs, Figure S2: Unsupervised analysis of the deletion data of the genes included in iEK1011 2.0 genome-scale metabolic model, Figure S3: Principal Component Analysis of FBA flux distributions of the lineage-specific genome-scale metabolic models, Figure S4: Principal Component Analysis of the sampled solution space of each one of the lineage-specific genome-scale metabolic models, Figure S5: OPLS-DA loadings for the significantly altered subsystems between animal- and human-associated sampled models, Figure S6: Difference of exchange fluxes between sampled models and FBA flux distribution of metabolites in Middlebrock 7H9 OADC + cholesterol for each lineage’s model, Table S1: Illumina genomes information, Table S2: iEK1011 2.0 reaction information, Table S3: Removed reactions per lineage model, Table S4: OPLS-DA variable coefficients, Table S5: Statistically significant reaction fluxes between samples of animal- and human-associated models, File S1: Description of the genes removed from iEK1011 2.0 to generate lineage-specific GEMs, File S2: Lineage-specific genome scale metabolic models., Peer reviewed
 
DOI: http://hdl.handle.net/10261/330900
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/330900

HANDLE: http://hdl.handle.net/10261/330900
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/330900
 
Ver en: http://hdl.handle.net/10261/330900
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/330900

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/330900
Dataset. 2022

SUPPLEMENTARY MATERIALS: IN SILICO EXPLORATION OF MYCOBACTERIUM TUBERCULOSIS METABOLIC NETWORKS SHOWS HOST-ASSOCIATED CONVERGENT FLUXOMIC PHENOTYPES

Digital.CSIC. Repositorio Institucional del CSIC
  • Santamaria, Guillem
  • Ruiz-Rodríguez, Paula
  • Renau-Mínguez, Chantal
  • Pinto, Francisco R.
  • Coscollá, Mireia
Figure S1: Correspondence Analysis of all the potentially deleterious SNPs, Figure S2: Unsupervised analysis of the deletion data of the genes included in iEK1011 2.0 genome-scale metabolic model, Figure S3: Principal Component Analysis of FBA flux distributions of the lineage-specific genome-scale metabolic models, Figure S4: Principal Component Analysis of the sampled solution space of each one of the lineage-specific genome-scale metabolic models, Figure S5: OPLS-DA loadings for the significantly altered subsystems between animal- and human-associated sampled models, Figure S6: Difference of exchange fluxes between sampled models and FBA flux distribution of metabolites in Middlebrock 7H9 OADC + cholesterol for each lineage’s model, Table S1: Illumina genomes information, Table S2: iEK1011 2.0 reaction information, Table S3: Removed reactions per lineage model, Table S4: OPLS-DA variable coefficients, Table S5: Statistically significant reaction fluxes between samples of animal- and human-associated models, File S1: Description of the genes removed from iEK1011 2.0 to generate lineage-specific GEMs, File S2: Lineage-specific genome scale metabolic models., Peer reviewed




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