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Distinct BEC and hepatocyte proportions: predictive in silico modelling of development and in vivo cell type quantification of postembryonic stages [Dataset]

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352120
Digital.CSIC. Repositorio Institucional del CSIC
  • Unterweger, Iris. A.
  • Klepstad, Julie
  • Hannezo, Edouard
  • Lundegaard, Pia R.
  • Trusina, Ala
  • Ober, Elke A.
(A-C) Mathematical models simulating hepatoblast differentiation, based on heterogeneous hepatoblast potentials (A, B) or differential proliferation times (C; n = 10). (D, F) Presentation of 10 μm sections from juvenile (D) and adult (F) livers stained for fabp10a:GFP (hepatocytes), tp1:H2B-mCherry (BECs), and DAPI (nuclei). (E) Relative distribution of BECs and hepatocytes in juvenile liver (N = 4, n = 4 livers and 18 ROIs). (G) Relative distribution of BECs and hepatocytes at the organ centre (N = 1, n = 1 liver, 4 sections) or periphery in adult livers (N = 1, n = 1 whole-mount liver). The numerical values that were used to generate the graphs in (A-C, E, G) can be found in S1 Data., Peer reviewed
 
DOI: http://hdl.handle.net/10261/352120
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352120

HANDLE: http://hdl.handle.net/10261/352120
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352120
 
Ver en: http://hdl.handle.net/10261/352120
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352120
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Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/352120
Dataset. 2023

DISTINCT BEC AND HEPATOCYTE PROPORTIONS: PREDICTIVE IN SILICO MODELLING OF DEVELOPMENT AND IN VIVO CELL TYPE QUANTIFICATION OF POSTEMBRYONIC STAGES [DATASET]

Digital.CSIC. Repositorio Institucional del CSIC
  • Unterweger, Iris. A.
  • Klepstad, Julie
  • Hannezo, Edouard
  • Lundegaard, Pia R.
  • Trusina, Ala
  • Ober, Elke A.
(A-C) Mathematical models simulating hepatoblast differentiation, based on heterogeneous hepatoblast potentials (A, B) or differential proliferation times (C; n = 10). (D, F) Presentation of 10 μm sections from juvenile (D) and adult (F) livers stained for fabp10a:GFP (hepatocytes), tp1:H2B-mCherry (BECs), and DAPI (nuclei). (E) Relative distribution of BECs and hepatocytes in juvenile liver (N = 4, n = 4 livers and 18 ROIs). (G) Relative distribution of BECs and hepatocytes at the organ centre (N = 1, n = 1 liver, 4 sections) or periphery in adult livers (N = 1, n = 1 whole-mount liver). The numerical values that were used to generate the graphs in (A-C, E, G) can be found in S1 Data., Peer reviewed

HANDLE: http://hdl.handle.net/10261/352120


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