BUSCADOR RECOLECTA

Digital.CSIC. Repositorio Institucional del CSIC

oai:digital.csic.es:10261/280951

5 páginas, 1 figura.--Trabajo presentado al: 12th World Congress on Genetics Applied to Livestock Production (WCGALP), R.F. Veerkamp and Y. de Haas (Eds), Wageningen Academic Publishers (Holanda), #705, pages 2909-2912. Róterdam (Holanda). 3-8 de julio de 2022., The proceedings of the 12th World Congress on Genetics Applied to Livestock Production provide you with 816 papers representing the leading research in livestock genetics around the globe. This book covers all aspects of genetics applied to livestock production in 44 sections. Next to the exciting plenary speakers, and the recurrent technical and species orientated sections, there are sections focusing on specific challenges for animal breeding. For instance, large-scale phenotyping of individual animals, use of whole genome sequence data and improving genomic prediction, and sessions on the contribution that genetics can make to societal challenges, like animal welfare, climate change, biodiversity, or control of infectious diseases., Prepubertal nutrition has been proposed as an important factor for feed efficiency and milk production in later life. Moreover, nutritional restrictions during prepubertal mammary gland development may influence the milk production potential. This study aims to evaluate the potential impact of a nutritional challenge during the allometric growth of the mammary gland on the milk transcriptome of dairy ewes with different feed efficiency phenotypes. The differential expression analyses identified 29 genes whose expression was significantly different for feed efficiency and relevant regarding the nutritional challenge. Eight differentially expressed genes were clustered under the biological process “cell adhesion”. Molecules involved in cell adhesion are crucial in the proper development and function of the mammary gland. In conclusion, the main genes impacted by the nutritional challenge and showing a different expression pattern related to feed efficiency could be involved in the development of the proper architecture of the mammary gland parenchyma., This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No 772787 (SMARTER)., Peer reviewed