. 2022

Replication data for PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus

Dipòsit Digital de Documents de la UAB
oai:ddd.uab.cat:259560
Dipòsit Digital de Documents de la UAB
  • Velasco García, Eric Raúl|||0000-0002-8778-5618
  • Andero Galí, Raül|||0000-0003-3641-8903
This dataset includes the source data related to the submission of the article "PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus" to Nature Communications. It includes data about mRNA and protein regulation of PACAP-PAC1R system after a stress paradigm coupled with a fear conditioning and fear extinction task. The effects of stress circuitry chemogenetic manipulation over PACAP-PAC1R regulation are also shown. Data from two cohorts of human participants are included, in the first cohort, the effects of the menstrual cycle over post-traumatic symptoms were investigated. In the second cohort, the effects of PACAP1R genotype in the SNP rs2267735 were investigated in a fear extinction task.
 

DOI: https://ddd.uab.cat/record/259560, https://dx.doi.org/10.5565/ddd.uab.cat/259560
Dipòsit Digital de Documents de la UAB
oai:ddd.uab.cat:259560

HANDLE: https://ddd.uab.cat/record/259560, https://dx.doi.org/10.5565/ddd.uab.cat/259560
Dipòsit Digital de Documents de la UAB
oai:ddd.uab.cat:259560
 
Ver en: https://ddd.uab.cat/record/259560, https://dx.doi.org/10.5565/ddd.uab.cat/259560
Dipòsit Digital de Documents de la UAB
oai:ddd.uab.cat:259560