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RUO. Repositorio Institucional de la Universidad de Oviedo
oai:digibuo.uniovi.es:10651/53529
Artículo científico antes de ser publicado, versión del editor (article), Imagen (Image)

UN NUEVU EMPLAZAMIENTU MILITAR ROMANU N'ASTURIES: EL CAMPAMENTU DE MOYAPÁN (AYANDE)

  • González Álvarez, David
  • Menéndez Blanco, Andrés

Proyecto: //
DOI: http://hdl.handle.net/10651/53529
RUO. Repositorio Institucional de la Universidad de Oviedo
oai:digibuo.uniovi.es:10651/53529
HANDLE: http://hdl.handle.net/10651/53529
RUO. Repositorio Institucional de la Universidad de Oviedo
oai:digibuo.uniovi.es:10651/53529
PMID: http://hdl.handle.net/10651/53529
RUO. Repositorio Institucional de la Universidad de Oviedo
oai:digibuo.uniovi.es:10651/53529
Ver en: http://hdl.handle.net/10651/53529
RUO. Repositorio Institucional de la Universidad de Oviedo
oai:digibuo.uniovi.es:10651/53529

e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/17379
Artículo científico antes de ser publicado, versión del editor (article), Dataset

HOW MUCH TRADE LIBERALIZATION WAS THERE IN THE WORLD BEFORE AND AFTER COBDEN-CHEVALIER?

  • Tena Junguito, Antonio
  • Lampe, Markus
  • Tâmega, Felipe
The Cobden-Chevalier Treaty of 1860 is regarded as central turning point in nineteenth-century trade policy, inaugurating a free trade era in Western Europe. We reexamine this story and put it into global perspective with a new database covering more than 7,500 data points for 11 categories of manufactures in 41 countries and colonies around the world between 1846 and 1880. It reveals that bilateralism after 1860 reinforced a process already underway before. Nevertheless, we highlight that trade liberalization was a global phenomenon over most of our period, so that the prominent British case appears as typical rather than exceptional., Financial support from the MCI: ECO2008-02089 and from MCI: ECO2011-25713, Publicado

Proyecto: //
DOI: http://hdl.handle.net/10016/17379
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/17379
HANDLE: http://hdl.handle.net/10016/17379
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/17379
PMID: http://hdl.handle.net/10016/17379
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/17379
Ver en: http://hdl.handle.net/10016/17379
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/17379

e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/23598
Artículo científico antes de ser publicado, versión del editor (article), Dataset

HUMANS DISPLAY A REDUCED SET OF CONSISTENT BEHAVIORAL PHENOTYPES IN DYADIC GAMES

  • Poncela-Casasnovas, Julia
  • Gutiérrez-Roig, Mario
  • Gracia-Lázaro, Carlos
  • Vicens, Julian
  • Gómez-Gardeñes, Jesús
  • Perelló, Josep
  • Moreno, Yamir
  • Duch, Jordi
  • Sánchez, Angel
Socially relevant situations that involve strategic interactions are widespread among animals and humans alike. To study these situations, theoretical and experimental research has adopted a game theoretical perspective, generating valuable insights about human behavior. However, most of the results reported so far have been obtained from a population perspective and considered one specific conflicting situation at a time. This makes it difficult to extract conclusions about the consistency of individuals' behavior when facing different situations and to define a comprehensive classification of the strategies underlying the observed behaviors. We present the results of a lab-in-the-field experiment in which subjects face four different dyadic games, with the aim of establishing general behavioral rules dictating individuals' actions. By analyzing our data with an unsupervised clustering algorithm, we find that all the subjects conform, with a large degree of consistency, to a limited number of behavioral phenotypes (envious, optimist, pessimist, and trustful), with only a small fraction of undefined subjects. We also discuss the possible connections to existing interpretations based on a priori theoretical approaches. Our findings provide a relevant contribution to the experimental and theoretical efforts toward the identification of basic behavioral phenotypes in a wider set of contexts without aprioristic assumptions regarding the rules or strategies behind actions. From this perspective, our work contributes to a fact-based approach to the study of human behavior in strategic situations, which could be applied to simulating societies, policy-making scenario building, and even a variety of business applications., This workwas partially supported byMineco (Spain) through grants FIS2013 47532 C3 1 P (to J.D.), FIS2013 47532 C3 2 P (to J.P.), FIS2012 38266 C02 01 (to J.G. G.), and FIS2011 25167 (to J.G. G. and Y.M.); by Comunidad de Aragón (Spain) through the Excellence Group of Non Linear and Statistical Physics (FENOL) (to C.G. L., J.G. G., and Y.M.); by Generalitat de Catalunya (Spain) through Complexity Lab Barcelona (contract no. 2014 SGR 608; to J.P. and M.G. R.) and through Secretaria d’Universitats i Recerca (contract no. 2013 DI 49; to J.D. and J.V.); and by the European Union through Future and Emerging Technologies FET Proactive Project MULTIPLEX (Multilevel Complex Networks and Systems) (contract no. 317532; to Y.M., J.G. G., and J.P. C.) and FET Proactive Project DOLFINS (Distributed Global Financial Systems for Society) (contract no. 640772; to C.G. L., Y.M., and A.S.).

DOI: http://hdl.handle.net/10016/23598, http://dx.doi.org/10.1126/sciadv.1600451
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/23598
HANDLE: http://hdl.handle.net/10016/23598, http://dx.doi.org/10.1126/sciadv.1600451
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/23598
PMID: http://hdl.handle.net/10016/23598, http://dx.doi.org/10.1126/sciadv.1600451
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/23598
Ver en: http://hdl.handle.net/10016/23598, http://dx.doi.org/10.1126/sciadv.1600451
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/23598

e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/25255
Artículo científico antes de ser publicado, versión del editor (article), Dataset

THE IMPACT OF IMMIGRATION: WHY DO STUDIES REACH SUCH DIFFERENT RESULTS?

  • Dustmann, Christian
  • Schoenberg, Uta
  • Stuhler, Jan
We classify the empirical literature on the wage impact of immigration into three groups, where studies in the first two groups estimate different relative effects, and studies in the third group estimate the total effect of immigration on wages. We interpret the estimates obtained from the different approaches through the lens of the canonical model to demonstrate that they are not comparable. We then relax two key assumptions in this literature, allowing for inelastic and heterogeneous labor supply elasticities of natives and the "downgrading" of immigrants. "Downgrading" occurs when the position of immigrants in the labor market is systematically lower than the position of natives with the same observed education and experience levels. Downgrading means that immigrants receive lower returns to the same measured skills than natives when these skills are acquired in their country of origin. We show that heterogeneous labor supply elasticities, if ignored, may complicate the interpretation of wage estimates, and particularly the interpretation of relative wage effects. Moreover, downgrading may lead to biased estimates in those approaches that estimate relative effects of immigration, but not in approaches that estimate total effects. We conclude that empirical models that estimate total effects not only answer important policy questions, but are also more robust to alternative assumptions than models that estimate relative effects., Jan Stuhler declares that he has received financial support by the Spanish Ministerio Economy Competitividad (Spain, MDM 2014-0431 and ECO2014-55858-P) and Comunidad de Madrid (MadEco-CM S2015/HUM-3444). Christian Dustmann declares that he has received financial support by the Norface Programme on Migration (funded by European national research councils) and the European Research Council, ERC Advanced grant DMEA.

Proyecto: //
DOI: http://hdl.handle.net/10016/25255, https://doi.org/10.1257/jep.30.4.31
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/25255
HANDLE: http://hdl.handle.net/10016/25255, https://doi.org/10.1257/jep.30.4.31
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/25255
PMID: http://hdl.handle.net/10016/25255, https://doi.org/10.1257/jep.30.4.31
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/25255
Ver en: http://hdl.handle.net/10016/25255, https://doi.org/10.1257/jep.30.4.31
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/25255

e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/28743
Artículo científico antes de ser publicado, versión del editor (article), Dataset

FIBROBLAST ACTIVATION AND ABNORMAL EXTRACELLULAR MATRIX REMODELLING AS COMMON HALLMARKS IN THREE CANCER-PRONE GENODERMATOSES

  • Chacón Solano, Esteban
  • León Canseco, Carlos
  • Diaz, F.
  • García-García, F.
  • García Díez, Marta
  • Escámez Toledano, María José
  • Guerrero Aspizua, Sara
  • Conti, Claudio Jorge
  • Mencía Rodríguez, Ángeles
  • Martínez Santamaría, Lucia
  • Llames, S.
  • Pévida, M.
  • Carbonell-Caballero, J.
  • Puig-Butille, J.A.
  • Maseda, R.
  • Puig, S.
  • Lucas, R. de
  • Baselga, E.
  • Larcher Laguzzi, Fernando
  • Dopazo, J.
  • Río Nechaevsky, Marcela del
Background. Recessive dystrophic epidermolysis bullosa (RDEB), Kindler syndrome (KS) and xeroderma pigmentosum complementation group C (XPC) are three cancer-prone genodermatoses whose causal genetic mutations cannot fully explain, on their own, the array of associated phenotypic manifestations. Recent evidence highlights the role of the stromal microenvironment in the pathology of these disorders. Objectives. To investigate, by means of comparative gene expression analysis, the role played by dermal fibroblasts in the pathogenesis of RDEB, KS and XPC. Methods. We conducted RNA-Seq analysis, which included a thorough examination of the differentially expressed genes, a functional enrichment analysis and a description of affected signalling circuits. Transcriptomic data were validated at the protein level in cell cultures, serum samples and skin biopsies. Results. Interdisease comparisons against control fibroblasts revealed a unifying signature of 186 differentially expressed genes and four signalling pathways in the three genodermatoses. Remarkably, some of the uncovered expression changes suggest a synthetic fibroblast phenotype characterized by the aberrant expression of extracellular matrix (ECM) proteins. Western blot and immunofluorescence in situ analyses validated the RNA-Seq data. In addition, enzyme-linked immunosorbent assay revealed increased circulating levels of periostin in patients with RDEB. Conclusions. Our results suggest that the different causal genetic defects converge into common changes in gene expression, possibly due to injury-sensitive events. These, in turn, trigger a cascade of reactions involving abnormal ECM deposition and underexpression of antioxidant enzymes. The elucidated expression signature provides new potential biomarkers and common therapeutic targets in RDEB, XPC and KS., This study was supported by grants from the Spanish Ministry of Economy and Competitiveness (SAF2013-43475R, SAF2017-88908-R and SAF2017-86810-R); from Instituto de Salud Carlos III and CIBERER, cofunded with European Regional Development Funds (ERDF) (PT13/0001/0007, PI14/00931, PI15/00716, PI15/00956, PT17/0009/0006 and PI17/01747); and from the European Union (HEALTH-F2-2011-261392 and H2020-INFRADEV-1-2015-1/ELIXIR-EXCELERATEref. 676559). Additional funding from Comunidad de Madrid (AvanCell-CM S2017/BMD-3692); Catalan Government (AGAUR 2014_SGR_603); ‘Fundacio' La Marató de TV3, 01331-30’; CERCA Programme/Generalitat de Catalunya; and ‘Fundación Científica de la Asociación Española Contra el Cáncer’, Spain.

Proyecto: EC/H2020/676559
DOI: http://hdl.handle.net/10016/28743, https://doi.org/10.1111/bjd.17698
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/28743
HANDLE: http://hdl.handle.net/10016/28743, https://doi.org/10.1111/bjd.17698
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/28743
PMID: http://hdl.handle.net/10016/28743, https://doi.org/10.1111/bjd.17698
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/28743
Ver en: http://hdl.handle.net/10016/28743, https://doi.org/10.1111/bjd.17698
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/28743

e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/20095
Artículo científico antes de ser publicado, versión del editor (article), Dataset

FORENSIC ANALYSIS OF VENEZUELAN ELECTIONS DURING THE CHÁVEZ PRESIDENCY

  • Jiménez, Raúl
  • Hidalgo Trenado, Manuel
Contiene adjunto ficheros de datos., Hugo Chavez dominated the Venezuelan electoral landscape since his first presidential victory in 1998 until his death in 2013. Nobody doubts that he always received considerable voter support in the numerous elections held during his mandate. However, the integrity of the electoral system has come into question since the 2004 Presidential Recall Referendum. From then on, different sectors of society have systematically alleged electoral irregularities or biases in favor of the incumbent party. We have carried out a thorough forensic analysis of the national-level Venezuelan electoral processes held during the 1998-2012 period to assess these complaints. The second-digit Benford's law and two statistical models of vote distributions, recently introduced in the literature, are reviewed and used in our case study. In addition, we discuss a new method to detect irregular variations in the electoral roll. The outputs obtained from these election forensic tools are examined taking into account the substantive context of the elections and referenda under study. Thus, we reach two main conclusions. Firstly, all the tools uncover anomalous statistical patterns, which are consistent with election fraud from 2004 onwards. Although our results are not a concluding proof of fraud, they signal the Recall Referendum as a turning point in the integrity of the Venezuelan elections. Secondly, our analysis calls into question the reliability of the electoral register since 2004. In particular, we found irregular variations in the electoral roll that were decisive in winning the 50% majority in the 2004 Referendum and in the 2012 Presidential Elections., This work was supported by the Spanish Ministry of Economy and Competitiveness (Projects ECO2011-25706 and CSO2012-35852).

Proyecto: //
DOI: http://hdl.handle.net/10016/20095
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/20095
HANDLE: http://hdl.handle.net/10016/20095
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/20095
PMID: http://hdl.handle.net/10016/20095
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/20095
Ver en: http://hdl.handle.net/10016/20095
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
oai:e-archivo.uc3m.es:10016/20095

Repositori Universitat Jaume I
oai:repositori.uji.es:10234/181710
Artículo científico antes de ser publicado, versión del editor (article), Dataset

EVALUATING THE EFFECT OF A LAW AS A SOCIAL INTERVENTION: TESTING THE LONG-RUN EFFECT OF AN INTERRUPTED TIME SERIES, EVALUACIÓN DEL EFECTO DE UNA LEY COMO UNA INTERVENCIÓN SOCIAL: COMPROBACIÓN DEL EFECTO A LARGO PLAZO DE UNA SERIE TEMPORAL INTERRUMPIDA

  • Rosel, Jesús F.
  • Jara Jiménez, Pilar
  • Garrigues Giménez, Amparo
  • Úbeda, Salvador
Contiene artículo y datos

Proyecto: //
DOI: http://hdl.handle.net/10234/181710
Repositori Universitat Jaume I
oai:repositori.uji.es:10234/181710
HANDLE: http://hdl.handle.net/10234/181710
Repositori Universitat Jaume I
oai:repositori.uji.es:10234/181710
PMID: http://hdl.handle.net/10234/181710
Repositori Universitat Jaume I
oai:repositori.uji.es:10234/181710
Ver en: http://hdl.handle.net/10234/181710
Repositori Universitat Jaume I
oai:repositori.uji.es:10234/181710

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