Role of Methylation in Modulating MAPK Signaling. Implications in Melanoma. Papel de la metilación como modulador de la señalización en MAPK. Implicaciones en melanoma.

Description: 1. General Overview MTAP is a key enzyme in the methionine salvage pathway and controls the levels of methylthioadenosine (MTA). Lost of MTAP, which is frequent in melanoma, results in higher intra and extracellular MTA levels. As MTA is an inhibitor of methylation reactions within the cell, we deci...
Language(s): Múltiples idiomas
Subject(s): Metilación , Melanoma , MAPK
Publisher(s): Universitat de Barcelona
Contributor(s): Recio Conde, Juan Ángel
Source(s):
Publication Date(s): 2012-03-12
Type(s): Tesis doctoral (doctoralThesis)
Rights(s): info:eu-repo/semantics/restrictedAccess
Relation(s):
Estadísticas: Ocultar/Mostrar estadísticas
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