Impaired trafficking and activation of tumor necrosis factor-α-converting enzyme in cell mutants defective in protein ectodomain shedding

Description: Protein ectodomain shedding is a specialized type of regulated proteolysis that releases the extracellular domain of transmembrane proteins. The metalloprotease disintegrin tumor necrosis factor-α-converting enzyme (TACE) has been convincingly shown to play a central role in ectodomain shedding, bu...
Language(s): Inglés
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Publisher(s): American Society for Biochemistry and Molecular Biology
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Publication Date(s): 2013-02-14T10:43:17Z
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Rights(s): closedAccess
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Estadísticas: Ocultar/Mostrar estadísticas
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