language = "Holandés"

Encontrado 44 documentos, página mostrada 4 de 5

PPARß/d activation blocks lipid-induced inflammatory pathways in mouse heart and human cardiac cells.

Description: Owing to its high fat content, the classical Western diet has a range of adverse effects on the heart, including enhanced inflammation, hypertrophy, and contractile dysfunction. Proinflammatory factors secreted by cardiac cells, which are under the transcriptional control of nuclear factor-?B (NF-?B...
Language(s): Holandés

Atorvastatin prevents peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) downregulation in lipopolysaccharide-stimulated H9c2 cells.

Description: Although abnormalities in cardiac fatty acid metabolism are involved in the development of several cardiac pathologies, the mechanisms underlying these changes are not well understood. Given the prominent role played by peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta in cardiac...
Language(s): Holandés

Agonist-induced activation releases peroxisome proliferator-activated receptor beta/delta from its inhibition by palmitate-induced nuclear factor-kappaB in skeletal muscle cells.

Author(s): Jové M , Laguna JC , Vazquez M
Description: The mechanisms by which elevated levels of free fatty acids cause insulin resistance are not well understood, but there is a strong correlation between insulin resistance and intramyocellular lipid accumulation in skeletal muscle. In addition, accumulating evidence suggests a link between inflammati...
Language(s): Holandés

Atorvastatin improves peroxisome proliferator-activated receptor signaling in cardiac hypertrophy by preventing nuclear factor-kappa B activation.

Description: Nuclear factor (NF)-kappa B signaling pathway plays a pivotal role in cardiac hypertrophy. Although it has been reported that statins inhibit cardiac hypertrophy by reducing generation of reactive oxygen species, it is not yet known whether statins prevent NF-kappa B activation and whether this effe...
Language(s): Holandés

Increased production of the ether-lipid platelet-activating factor in intestinal epithelial cells infected by Salmonella enteritidis.

Description: When exposed to enteric pathogens intestinal epithelial cells produce several cytokines and other proinflammatory mediators. To date there is no evidence that the ether-lipid platelet-activating factor (PAF) is one of these mediators. Our results revealed a significant increase in PAF production by ...
Language(s): Holandés

Inactivation of propanediol oxidoreductase of Escherichia coli by metal-catalyzed oxidation.

Description: 1,2-Propanediol oxidoreductase, which reduces the L-lactaldehyde formed in the fermentation of L-fucose or L-rhamnose to L-1,2-propanediol in E. coli, was inactivated by a component of E. coli cell extracts in the presence of oxygen. Pure propanediol oxidoreductase preparations were shown to be inac...
Language(s): Holandés

Reduced novelty-P3 associated with increased behavioral distractibility in schizophrenia.

Description: Behavioral and electrophysiological brain responses were used to examine the relationship between the vulnerability to distraction and the orienting response in schizophrenia. Nineteen schizophrenics and nineteen matched healthy controls were instructed to ignore task-irrelevant auditory stimuli whi...
Language(s): Holandés

Impaired preparatory re-mapping of stimulus-response associations and rule-implementation in schizophrenic patients--the role for differences in early processing.

Description: An accurate representation of task-set information is needed for successful goal directed behavior. Recent studies point to disturbances in the early processing stages as plausible causes for task-switching deficits in schizophrenia. A task-cueing protocol was administered to a group of schizophreni...
Language(s): Holandés

Electrophysiological and behavioral evidence of gender differences in the modulation of distraction by the emotional context.

Description: Gender differences in brain activity while processing emotional stimuli have been demonstrated by neuroimaging and electrophysiological studies. However, the possible differential effects of emotion on attentional mechanisms between women and men are less understood. The present study aims to elucid...
Language(s): Holandés

On the functional significance of Novelty-P3: facilitation by unexpected novel sounds.

Description: The unexpected occurrence of a change in the auditory context has been shown to result in distraction due to a momentary attention shift. These unexpected sounds elicit the Novelty-P3 (NP3) response which has been proposed as an electrophysiological index of distractibility, and used as such in the ...
Language(s): Holandés

Encontrado 44 documentos, página mostrada 4 de 5

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