author = "Bermejo Pareja, Félix"

Encontrado 55 documentos, página mostrada 1 de 6

On the mechanism of inhibition of p27 degradation by 15-deoxy-Δ12,14-prostaglandin J 2 in lymphoblasts of Alzheimer’s disease patients

Description: 13 páginas, 10 figuras -- PAGS nros. 3507-3519 , We have analyzed the intracellular signals that allow lymphoblasts from Alzheimer’s disease (AD) patients to escape from serum deprivation-induced apoptosis. The following observations suggested that modulation of ERK1/2 activity by Ca2+/calmodulin (CaM)...
Language(s): Inglés

Enhanced proteasome-dependent degradation of the CDK inhibitor p27kip1 in immortalized lymphocytes from Alzheimer´s dementia patients

Description: 11 páginas, 11 figuras -- PAGS nros. 1474-1484 , Cyclin-dependent kinase inhibitor p27kip1 (p27), a critical determinant for cell cycle progression, is an important regulation target of mitogenic signals. We have recently reported the existence of a molecular link between decreased p27 levels and enhan...
Language(s): Inglés

On the mechanism of inhibition of p27 degradation by 15-deoxy-Δ12,14-prostaglandin J 2 in lymphoblasts of Alzheimer’s disease patients

Description: 13 páginas, 10 figuras -- PAGS nros. 3507-3519 , We have analyzed the intracellular signals that allow lymphoblasts from Alzheimer’s disease (AD) patients to escape from serum deprivation-induced apoptosis. The following observations suggested that modulation of ERK1/2 activity by Ca2+/calmodulin (CaM)...
Language(s): Inglés

Análisis infrarrojo de fracciones de sangre periférica obtenida para indicar desarrollo cognitivo asociado a la enfermedad de Alzheimer

Description: La presente invención se refiere a un método de análisis espectroscópico infrarrojo de transmisión para determinar el grado de deterioro global cognitivo asociado a la enfermedad de Alzheimer basado en analizar la región 3100-1300 cm-1 del espectro de infrarrojo de una muestra de sangre previamente ...
Language(s): Español

Enhanced proteasome-dependent degradation of the CDK inhibitor p27kip1 in immortalized lymphocytes from Alzheimer´s dementia patients

Description: 11 páginas, 11 figuras -- PAGS nros. 1474-1484 , Cyclin-dependent kinase inhibitor p27kip1 (p27), a critical determinant for cell cycle progression, is an important regulation target of mitogenic signals. We have recently reported the existence of a molecular link between decreased p27 levels and enhan...
Language(s): Inglés

Infrared analysis of peripheral blood fractions obtained to indicate cognitive development associated with alzheimer's disease Analisis infrarrojo de fracciones de sangre periferica obtenida para indicar desarrollo cognitivo asociado a la enfermedad de alzheimer

Description: [EN] The invention relates to a method for transmission infrared spectroscopy for determining the degree of global cognitive deterioration associated with Alzheimer's disease, on the basis of analysis of the 3100-1300 cm-1 region of the infrared spectrum of a previously obtained and fractionated blo...
Language(s): Español

Validación de un protoclo clínico para la detección de demencia en el ámbito poblacional

Description: Validación de un protocolo clínico para la detección de demencia en ámbito poblacional , To analyse the validity of a set of neuropsychological and functional tests, and to study their value in detectingand diagnosing dementia through a pilot study. Patients and methods. A total of 131 subjects (101 co...
Language(s): Español

Understanding care of people with dementia in Spain: Cohabitation arrangements, rotation and rejection to long term care institution

Description: Se describe los cuidados de la población con demencia en España : acuerdos de convivencia entre familiares y prácticas de rotación, con rechazo a las instituciones de larga instancia. , Most people with dementia in Spain live at home with their families. Current changes in the family structure are tra...
Language(s): Inglés

3HMG-CoA reductasa inhibitor, simvastatin, inhibits cell cycle progression at the G1-S checkpoint in immortalized lymphocytes from Alzheimer´s disease patients independently of cholesterol lowering effects

Description: 8 páginas, 8 figuras -- PAGS nros. 352-359 , Recent work has suggested that statins may exert beneficial effects on patients suffering from Alzheimer's disease (AD). The pharmacological effects of statins extend beyond their cholesterol-lowering properties. Based on the antineoplastic and apoptotic eff...
Language(s): Inglés

Encontrado 55 documentos, página mostrada 1 de 6

Uso de cookies: Este sitio web utiliza cookies propias y de terceros para dar un mejor servicio. Si continúa navegando se considera que acepta su uso. OKMás información