author = "Carro E"
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Encontrado 3 documentos, página mostrada 1 de 1

High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents.

Description: Global obesity is a pandemic status, estimated to affect over 2 billion people, that has resulted in an enormous strain on healthcare systems worldwide. The situation is compounded by the fact that apart from the direct costs associated with overweight pathology, obesity presents itself with a numbe...
Language(s): Holandés

Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer's Disease.

Description: There is growing evidence that obesity associated with type 2 diabetes mellitus (T2DM) and aging are risk factors for the development of Alzheimer's disease (AD). However, the molecular mechanisms through which obesity interacts with ß-amyloid (Aß) to promote cognitive decline remains poorly underst...
Language(s): Inglés

MAPT H1 haplotype is associated with late-onset Alzheimer's disease risk in APOE ¿ 4 noncarriers: Results from the dementia genetics Spanish consortium

Description: The MAPT H1 haplotype has been linked to several disorders, but its relationship with Alzheimer's disease (AD) remains controversial. A rare variant in MAPT (p.A152T) has been linked with frontotemporal dementia (FTD) and AD. We genotyped H1/H2 and p.A152T MAPT in 11,572 subjects from Spain (4,327 A...
Language(s): Inglés
1

Encontrado 3 documentos, página mostrada 1 de 1

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