Tipo de documento

Publicación principal: ES2685868A1 (11-10-2018) ; Solicitudes: P201830178 (27-02-2018), [ES] Método y dispositivo para prosumo eléctrico inteligente, de gestión inteligente de cargas en instalaciones con autoconsumo. El método comprende determinar las cargas gestionables de la instalación y su demanda energética en un período de gestión; obtener el consumo de la instalación; determinar el potencial de autoconsumo de la instalación según la capacidad de generación y acumulación energética y el consumo de la instalación; generar, para cada carga gestionable, un perfil de consumo...

Inscripción de derechos de propiedad intelectual., [ES] La herramienta “Aplicativo para el Cálculo Básico de Instalaciones de Autoconsumo Solar Fotovoltaico" describe un programa informático diseñado como herramienta de soporte para ingenieros, gestores energéticos y ciudadanos interesados en integrar sistemas de generación solar fotovoltaica para autoconsumo en sus instalaciones eléctricas. Este software ayuda a evaluar la viabilidad económica y energética de instalaciones de autoconsumo solar fotovoltaico, adaptándose a los...

Inscripción de derechos de propiedad intelectual., [ES] La herramienta avanzada para el pre-análisis de consumos eléctricos horarios, diseñada por el Grupo de Investigación ERESMA en colaboración con el Ente Regional de la Energía de Castilla y León. Esta herramienta, desarrollada en el contexto del Proyecto Art. 83, está programada en Microsoft Excel y está específicamente adaptada para analizar los consumos eléctricos en los edificios administrados por la Junta de Castilla y León. La funcionalidad principal de esta herramienta radica en su...

[ES] Sistema y método de interacción en entornos virtuales. El método comprende: detectar una orden de zoom de una escena virtual inicial; generar, por parte de una unidad de procesamiento gráfico, una nueva escena virtual a partir de la escena virtual inicial con un nivel de ampliación modificado en función de la orden de zoom detectada; mapear el espacio de trabajo de un dispositivo háptico con el espacio que representa la nueva escena virtual; y representar la nueva escena virtual. La orden...

[ES] Método, sistema y producto de programa para interacción en entornos de realidad virtual mediante dispositivo háptico de realimentación de fuerzas de escritorio (502). El método (100) comprende: definir (102) un espacio de acción (210) en un entorno de realidad virtual correspondiente con un espacio de trabajo (510) del dispositivo háptico de realimentación de fuerzas de escritorio (502); ante la detección (104) de una orden de modificación (512) del espacio de acción (210), modificar (106...

Número de publicación: 2 817 926, La patente ha sido extendida a otros paises (USA, Unión Europea, Chile), con las consiguientes redacciones modificadas (también en idioma inglés, en el caso de USA y la UE). Los respectivos enlaces a dichos documentos son: https://patentscope.wipo.int/search/es/detail.jsf?docId=US398808243&_fid=ES321560407 https://patentscope.wipo.int/search/es/detail.jsf?docId=WO2021064273&_fid=CL380271197 https://patentscope.wipo.int/search/es/detail.jsf?docId=CL380271197&_fid=ES321560407, Código visual y procedimiento para codificar y decodificar una imagen bidimensional. La presente descripción se refiere a un código visual 2D basado en la superposición de ondas planas puras enmarcadas en negro, diseñado para poder ser leído a largas distancias, con diferentes tipos de degradación (ruido, desenfoque o movimiento) y en condiciones de iluminación adversas. Para ello, los elementos portadores de información son ondas que están distribuidas por toda la imagen. La combinación de...

A computer network-storage protocol system, including at least one initiator device having an initiator block layer and an initiator network layer interfacing with a first network driver; at least one target device having a target block layer and a target network layer interfacing with a second network driver; a plurality of network interface controllers (NICs) interfacing with the first network driver and the second network driver; a plurality of distinct channels, each channel establishing a...

Patente de invención con examen sustantivo e informe favorable sobre el estado de la técnica, Receptor solar para colector de disco parabólico. Consiste en un absorbedor cilíndrico con cavidad que, estando situado en el punto focal de la parábola, capta la radiación solar reflejada desde el colector. Por la parte más caliente del receptor entra un fluido caloportador que recorre el receptor a lo largo de un circuito en forma de espiral practicado en el interior del mismo. El fluido, finalmente, sale del receptor a una temperatura considerablemente más alta y es conducido al...

El agregado de trióxido mineral fue desarrollado para sellar las comunicaciones existentes entre el diente y los tejidos externos, pero, aunque se ha investigado y empleado en múltiples y diversas intervenciones en el ámbito odontológico, anteriormente no se ha indicado ni planteado su uso como material de restauración dental (Torabinejad y cols., 1995 b, 1997 y 1999; Torabinejad y Chivian, 1999). El producto que proponemos salvaría este inconveniente ya que el cemento no tiene un coste...

Patente de índole nacional (española), no extendida a otros paises., Número de publicación: 2 817 652, Se refiere a un código visual que comprende una matriz bidimensional de celdas y un marco de color oscuro que rodea la matriz. Ésta comprende al menos uno de uno o más grupos de cuatro celdas en los que están dispuestas en dos filas y dos columnas, y, en la posición de lectura del código visual, dos de las celdas, de las tres que forman la primera fila y la primera columna, son cada una de color claro y/o color oscuro, y las dos restantes son de colores diferentes entre sí, de una pluralidad de...

International Publication Number: WO 2016/198698 A3 (WIPO/PCT), The present invention provides p38 inhibitors which are useful for the treatment and/or prophylaxis of liver cancer. In particular, the present invention provides compounds capable of inhibiting the intracellular expression of the p38 gamma protein in the hepatocytes of a subject relative to that observed in the absence of the compound, for use in the therapeutic treatment of liver cancer.

The theory of 2-Segal sets has connections to various important constructions such as the Waldhausen S center dot-construction in algebraic K-theory, Hall algebras, and (co)operads. In this paper, we construct 2-Segal sets from rooted trees and explore how these applications are illustrated by this example.

Proyecto de investigación realizado en la Freie Universität Berlin, Alemania, entre 2010 y 2012 desarrollando el proyecto titulado "El problema ontológico de la mímesis", el cual continuaba y desarrollaba planteamientos esbozados en mi tesis doctoral ("Problemas hermenéuticos en la lectura de la Ilíada"). Se pretendía examinar la noción de «mímesis» que se critica en el libro décimo de "La república". Se observó que 1. la actividad de Homero y los «poetas» era..., Report for the scientific sojourn carried out at the Freie Universität Berlin, Germany, from 2010 to 2012. This study was focused in the analysis of the notion of mimesis which is criticized in Book 10 of Plato's "Republic". I concluded that 1. the activity of Homer and the "poets" is analyzed by Plato in terms of a claim to "knowledge" 2. the notion of "knowledge" that works on the basis of philosophical analysis is the correct treating of...

La cuestión de los refugiados palestinos es uno de los asuntos clave para alcanzar una resolución firme del conflicto palestino-israelí. Para ello debe resolverse la situación de los cientos de miles de palestinos que fueron expulsados y/o huyeron con la guerra de 1948, y sus descendientes, que hoy suman casi 5 millones. En el proceso de paz, este es uno de los asuntos que ni siquiera fue tenido en cuenta con la profundidad que lo requiere. Los palestinos se acogen a la resolución 194 de la..., The Palestinian refugee issue is a key factor to reach a consistent resolution for the Israeli-Palestinian conflict. In order to accomplish it the first thing to do is to give a perspective on the situation of hundreds of thousands of Palestinians, and their descendants, who were banned or had to escape with the war of 1948. Today they are almost five million. Despite of its importance for the peace process, this topic was not considered with the deepness that requires. Palestinians are..., La qüestió dels refugiats palestins és un dels temes claus per arribar a una resolució viable del conflicte israelo-palestí. Per això s’ha de resoldre la situació dels centenars de milers de palestins que van ser expulsats i/o van fugir amb la guerra de 1948, i per als seus descendents, que avui són més de 5 milions. En el procés de pau, aquest va ser un dels assumptes que no va ser tingut en compte amb la profunditat que requereix. Els palestins s’acullen a la resolució 194 de l’Assemblea de...

Entre l'abril de 2007 i l'abril del 2011 vaig gaudir d'un ajut FI al Departament de Traducció i Ciencies del Llenguatge de la Universitat Pompeu Fabra. Gràcies a aquest ajut i en el marc del programa de doctorat en Comunicació Multilingüe vaig poder dur a terme un projecte de recerca sobre la recepció de la narrativa catalana traduïda a l'alemany des de 1975 fins a l’actualitat. El primer resultat d'aquest projecte és el nou treball de recerca, llegit el novembre de..., Between April 2007 and April 2011 I received a FI scholarship at the Department of Transtation and Language Sciences of the Pompeu Fabra University. Thanks to this support and within the framework of my PhD in Multilingual Communication I was able to submit a research project on the reception of the Catalan narrative in German translation from 1975 to the present. The first result of this proiect is mv research studv read in November 2010, in which I attempt to make an evalation of the Catalan...

El projecte de recerca que s’ha dut a terme els darrers tres anys consisteix en una reflexió teòrica al voltant de l’autoria literària, fent especial èmfasi en les implicacions de gènere dels processos de legitimació literària i les posicions autorials que se’n deriven. Clarice Lispector en tant que nom d’autor sota el qual s’agrupa no només un corpus literari sinó tots aquells textos que construeixen un cos d’autora, constitueix l’objecte d’anàlisi a partir del qual es posa en joc la reflexió..., This research project is a theoretical reflection about literary authorship, with special emphasis on the gender implications of the literary positions and the processes of legitimation in the literary field. Clarice Lispector as a name of author which grouped not only literary texts but also these texts that build the body of the author is the object of our analysis. To carry it out, we analyze the auto(bio)graphic production of Clarice Lispector and those discourses that contribute to the...

La tècnica de la microdiàlisis cerebral (MDC) és un instrument que proporciona informació rellevant en la monitorització del metabolisme cerebral en els pacients neurocrítics. El lactat i l’índex lactat-piruvat (ILP) són dos marcadors utilitzats per a la detecció de la hipòxia cerebral en pacients que han patit un traumatisme cranioencefàlic (TCE). Aquests dos marcadors poden estar anormalment elevats en circumstàncies que no cursen amb hipòxia tissular. Per una altra banda la recent aparició..., Cerebral microdialysis is a tool that provides very relevant information in the metabolic monitoring of brain injured patients. Lactate and the lactate-pyruvate ratio (LPR) are two hypoxia markers widely used to detect brain tissue hypoxia in patients with acute traumatic brain injury. These two markers can be abnormally high in circumstances with no brain hypoxia. On the other hand the recent availability of microdialysis catheters with membrane pores of larger size, termed “high resolution”...

We analyse models for panel data that arise in risk allocation problems,when a given set of sources are the cause of an aggregate risk value. We focus on the modeling and forecasting of proportional contributions to risk. Compositional data methods are proposed and the regression is flexible to incorporate external information from other variables. We guarantee that projected proportional contributions add up to 100%, and we introduce a method to generate confidence regions with the same...

En los transplantes de progenitores hematopoyéticos, la sangre de cordón umbilical es una fuente establecida de células madre hematopoyéticas que presenta como mayor ventaja una menor incidencia de enfermedades de injerto contra el huésped. Sin embargo, el bajo número de células madre obtenidas de una sola unidad limita su utilización a un número reducido de pacientes. Las células madre hematopoyéticas se definen por su capacidad de automantenimiento y reconstitución de todo el sistema..., Over the last decade the use of umbilical cord blood as a source of hematopoietic stem cells (HSCs) has increased due to its quick availability and because it allows the usage of mismatched donors, thus reducing the risk of graft versus host disease. Hematopoietic stem cells are defined by their capacity to self-renew and reconstitute the entire blood system of a transplanted recipient. In mouse, the use of cell surface markers has allowed an accurate HSC isolation by fluorescence activated...

Durante el siglo XV Cerdeña desempeña, gracias a su posicionamiento geográfico en el centro del Mediterráneo, un papel muy importante en la red de comercio internacional. Este movimiento económico-cultural fomenta una extensa producción artística que está caracterizada por depender fuertemente de la presencia en la isla de talleres y artistas catalanes. Al día de hoy se conoce muy poco la presencia y las características de la pintura del gótico tardío en la Cerdeña. Las dificultades encontradas..., Sardinia in the XV century to its geographical location in the center of the Mediterranean, a very important role in the international trade network. This economic-cultural movement promotes an extensive artistic production that is strongly characterized by dependence on the presence on the island of Catalan artists and workshops. Nowadays the presence and characteristics of late Gothic painting is very little known. The investigators finded numerous difficulties to the reconstruction of...

En aquest treball, es proposa un nou mètode per estimar en temps real la qualitat del producte final en processos per lot. Aquest mètode permet reduir el temps necessari per obtenir els resultats de qualitat de les anàlisi de laboratori. S'utiliza un model de anàlisi de componentes principals (PCA) construït amb dades històriques en condicions normals de funcionament per discernir si un lot finalizat és normal o no. Es calcula una signatura de falla pels lots anormals i es passa a través d..., In this work, a new method to estimate in real-time the quality of final product in batch processes is proposed. This method allows reducing the required time to obtain the quality results by laboratory analysis. A Principal Component Analysis (PCA) model built with historical data in normal operation condition is used to discern if a released batch is normal or not. For abnormal batches, a fault signature is calculated and passes through a classification model for the estimation. The study...

The invention relates to an isotopically marked material comprising a functional synthetic polymer and optionally a functional additive and to its use in the detection of material contamination or degradation or wear, preferably when said material is an industrial material, a space material or a prosthetic material., INSTITUTO NACIONAL DE TÉCNICA AEROESPACIAL, INSTITUTO TECNOLÓGICO DEL PLÁSTICO (AIMPLAS), Solicitud de Patente

La presente invención se refiere al uso de una composición que comprende N-acetilcisteína (NAC) para el tratamiento, prevención y/o recuperación de efectos tóxicos en peces expuestos a Microcistinas (MCs). También se refiere al uso de la citada composición en la recuperación de las alteraciones histopatológicas producidas en los tejidos de la lista que comprende hígado, riñón, corazón, branquias y/o tracto gastrointestinal. Además, dicha composición se utiliza para la fabricación de un alimento...

La presente invención se refiere a un procedimiento que permite autentificar obras de arte, preferentemente de arte digital, es decir, el que se realiza con dispositivos electrónicos de computación, aunque podría aplicarse perfectamente a otros tipos de obras de arte efectuadas con otros dispositivos, de manera que la autenticidad del autor o autores quede perfectamente protegida, junto con los derechos que puedan derivarse de ella. En esta invención, los datos de la obra de arte y su autor se...

La presente invención proporciona un método de obtención de datos útiles para predecir cual será la respuesta de un paciente al tratamiento de la hepatitis C, específicamente al tratamiento con interferón pegilado y ribavirina (Peg-IFN/RBV). Los autores de la invención han encontrado un biomarcador génico que permite predecir la respuesta al tratamiento de la hepatitis C. Esto es de gran utilidad en la práctica clínica para determinar la terapia a aplicar en cada paciente, dentro de los que se...

La presente invención se refiere a un dispositivo reductor de la resistencia aerodinámica (Drag), que comprende una pluralidad de alerones instalables en la superficie trasera de un vehículo, estando configurados dichos alerones para formar una multi-cavidad en dicha superficie trasera, formada por cuatro o más cavidades. Dichas cavidades poseen una forma preferentemente cuadrada o rectangular

La presente invención se encuentra dentro del campo de la Biología Molecular y la Medicina. Específicamente, se refiere a un método de obtención de datos útiles para la clasificación, diagnóstico y seguimiento del cáncer de pulmón mediante el análisis de los biomarcadores, especialmente la fenilalanina, ácido nonanedioico, ácido subérico, MG (22:2) y maltotetraosa en una muestra biológica, preferiblemente sudor.

La presente invención se refiere a un procedimiento, amigable con el medio ambiente, de presentación y decoración de envases alimentarios con el objetivo de evitar/minimizar la contaminación del alimento que contiene a través de las pinturas empleadas en la decoración. De este modo se favorece además el reciclaje de los envases

La invención consiste en un dispositivo de electrodo que permite la formación de plasma con cualquier gas aplicando el potencial RF adecuado, no siendo imprescindible iniciarlo con otro gas colaborador. La aplicación más importante consiste en realizar con este plasma la descomposición de hidrocarburos y otros compuestos para la generación de grafenos. Estos materiales novedosos, en forma pura, como nanografenos, o modificados en forma de azagrafenos o bien óxidos de grafeno o ácidos grafíticos...

l INCLISAFE RGIS1 es un dispositivo de aviso de riesgo de vuelco para vehículos militares. Está pensado y diseñado para avisaral conductor de una situación de inestabilidad del vehículo que conduce, de modo que la señal de aviso será más insistente conforme el riesgo de vuelco aumente. Se encuentra patentado en Estados Unidos (nº 3IPDT1.0002WO). Surge a partir del INCLISAFE para vehículos agroforestales desarrollado por el G.I. AGR 126 “Mecanización y Tecnología Rural” para la empresa EGMASA (...

La presente invención se refiere al uso del contenido intracelular de células madre mesenquimales (MSC) en la elaboración de un medicamento para el tratamiento de lesiones músculo-esqueléticas, entre otras la osteoartrosis. Los autores de la presente invención han evaluado el efecto beneficioso del contenido intracelular de las células mesenquimales (MSCs) en lesiones músculo esqueléticas. Además han encontrado una serie de diferencias que indican que la infusión de contenido intracelular de...

La presente invención se encuadra en el campo general del sector agroalimentario y en particular, se refiere a un método para la determinación de la pureza racial de la especie porcina (raza ibérica) y de productos derivados. Los autores de la presente invención han evaluado diferentes metodologías para la determinación del origen racial de los cerdos de diferentes razas, diseñando marcadores moleculares diagnóstico de tipo SNP útiles para la discriminación racial de animales vivos, productos...

La presente invención se encuadra en el campo de la producción de nanoestructuras de carbono y más especialmente se refiere a un procedimiento de síntesis de grafeno. Los autores de la invención han diseñado el dispositivo y desarrollado un procedimiento para la síntesis de grafeno en polvo a partir de la descomposición de una fuente de carbono por un plasma de microondas a presión atmosférica. El plasma se genera en el extremo de un vástago por el que circula un gas inerte y al que se acopla...

La presente investigación se enfoca en el campo de dispositivos optoelectrónicos, concretamente en células solares basadas en perovskitas hibrídas orgánicas-inorgánicas, las cuales han emergido recientemente como un material prometedor para complementar o reemplazar a las actuales células solares basadas en silicio (Si). Los investigadores del Departamento de Química Física y Termodinámica Aplicada/ Instituto de Química Fina y Nanoquímica (UCO) en colaboración con el Group of Molecular...

La presente invención se encuadra en el campo general de la química de productos naturales y en particular se refiere a un procedimiento para la obtención de carotenoides a partir de biomasa, y al uso de dichos productos en la industria farmacéutica y alimentaria donde los carotenoides se utilizan como suplementos nutricionales y aditivos. Los carotenoides (carotenos y xantofilas) son pigmentos naturales utilizados como aditivos alimentarios en acuicultura para la coloración de la carne de los...

La presente invención se encuadra en el campo general del sector agroalimentario y en particular, se refiere a un método para la determinación de la pureza racial de un ejemplar de la especie porcina o de los productos derivados del mismo., Método para la determinación de la pureza racial de un ejemplar de especie porcina y/o productos derivados del mismo. La presente invención se refiere a un método para la determinación de la pureza racial de un ejemplar de especie porcina y/o productos derivados del mismo mediante la detección en una muestra obtenida del animal o del producto a analizar, de al menos un SNP nuclear seleccionado de entre situados en las posiciones 1318 del gen mc1r y 3072 el gen igf2 y del al menos un SNP...

Método para el diagnóstico precoz de la infertilidad equina. La presente invención se refiere a un método in vitro para el diagnóstico de infertilidad equina de origen genético mediante la detección de los marcadores ECAX: LEX026, TKY38, TKY270, LEX003, UCDEQ502, y los marcadores ECAY: Eca.YH12 y SRY. Al uso de dichos marcadores ECAX y ECAY para el diagnóstico de la infertilidad equina de origen genético.

Embargado hasta 01/01/2100., A new and distinct variety of olive tree, herein referred to by its cultivar name, ‘ I-15 ', is provided which forms an upright to spreading tree growth habit. Fruit with a medium weight is produced. The fruit exhibit black coloration and the fruit nipple is absent or weak. The stone of the fruit of the new variety is of medium weight.

Aplicación informática de ayuda para el día a día de la profesión médica

Aplicación informática de ayuda para el día a día de la profesión médica

A system for modeling a roof of a structure comprising a first database, a second database and a processor in communication with the first database and the second database. The processor selects one or more images and the respective metadata thereof from the first database based on a received a geospatial region of interest. The processor generates two-dimensional line segment geometries in pixel space based on two-dimensional outputs generated by a neural network in pixel space of at least one...

Patente de un procedimiento, Se describe un procedimiento de obtención de grafeno modificado covalentemente. Asimismo, se describe el grafeno modificado covalentemente obtenible mediante dicho proceso de obtención, así como a su uso como superficie de anclaje de bioreceptores en dispositivos biosensores. Finalmente, se describe un dispositivo biosensor que comprende el grafeno modificado covalentemente obtenible de acuerdo con el procedimiento de la invención.

Systems and methods for fine adjustment of computerized roof models are provided. The system generates a 3D roof structure model based on at least one image obtained from an aerial imagery database. Alternatively, the system could retrieve at least one stored 3D roof structure model from a 3D roof structure model database. The system weighs (e.g., scores) each 3D roof structure model candidate and determines an optimal 3D roof structure model by applying a variable neighborhood search to a 3D...

Introduction: No specific instruments are available to detect the risk of suicide in women during the perinatal period. Suicide in perinatal women is little studied despite being one of the main causes of maternal mortality. Its prevalence has increased by 100% in the United States in a decade. Moreover, it has consequences for the mother and the newborn. Objective: To validate the Paykel Suicide Scale and the Plutchik Suicide Risk Scale in Spanish women during the perinatal period. Materials...

Introduction: No specific instruments are available to detect the risk of suicide in women during the perinatal period. Suicide in perinatal women is little studied despite being one of the main causes of maternal mortality. Its prevalence has increased by 100% in the United States in a decade. Moreover, it has consequences for the mother and the newborn. Objective: To validate the Paykel Suicide Scale and the Plutchik Suicide Risk Scale in Spanish women during the perinatal period. Materials...

Filing Date: 2004-07-14.-- Priority Data: ES 200301666 (2003-07-15).-- International Publication Number: WO_2005008175 (20050127)., This invention is related to the production engineering industry, and more particularly to the sector concerned with the production of photovoltaic cells, and therefore it also has a bearing on the alternative energy sector. The invention relates to the control of the methods used for texturing the surface of monocrystalline silicon, although it is also applicable to the textures developed on the surface of silicon and other multicrystalline and polycrystalline semiconductors.

Filing Date: 2002-06-14.-- Priority Data: ES 200101419 (2001-06-18).-- International Publication Number: WO_2002103038 (20021227)., An enzymatic process to obtain 4-O-β-D-galactopyranosyl-D-xylose useful in compositions or solutions in the in vivo evaluation of intestinal lactose activity in humans, that comprises the steps of preparing a reaction mixture of D-xylose, a β-D-galactopyranoside and a reaction medium that comprises water buffered to a pH between 5.0 and 9.0; adding 10 to 1,000 units of β-D-galactosidase per gram of β-D-galactopyranoside; subjecting the reaction mixture to a reaction or a temperature between a...

Filing Date: 2002-06-06.-- Priority Data: ES P 0101328 (2001-06-07), The method involves the following steps: a) leaching said IGCC ashes with an extracting agent selected amongst water, an aqueous solution of an acid and an aqueous solution of a base in order to solubilize all or part of the Ge contained in said IGCC ashes; b) separating the solid and liquid phases in the solution or suspension resulting from step a) into a solid phase (S1) and a liquid phase (L1) which contains the Ge and c) recovering the Ge in said liquid phase (L1). The inventive method...

Filing Date: 2004-02-20.--Priority Data ES P200300428 (2003-02-21), The invention relate to a method for the immobilisation of biomacromolecules on supports that are activated with epoxide groups.More specifically, the invention relates to a method for the immobilisation of enzymes and proteins on said type of support, which comprises two consecutive steps, namely: (a) very rapid ionic absorption of the enzyme on the support which is ionised under very gentle experimental conditions; and (b) intense multipoint covalent immobilisation between the previously...

Filing Date: 2003-11-28.-- Priority Data ES P200202751 (2002-11-29), The invention relates to improved magnetic particles which are suitable for the preparation of biosensors consisting of antibodies and antigens immobilised on the aforementioned magnetic particles. The inventive magnetic particles take the form of iron oxide particles measuring between 5 and 30 nm, which are disposed in a basic medium, presenting a silica coating with a thickness of between 30 and 100 nm. Said particles are characterised in that they have been subjected to a heat treatment at...

Filing Date: 2003-02-14.-- Priority Data ES P200200419 (2002-02-21), The invention relates to a method for the hydrolysis of lactose catalysed by immobilised/stabilised recombinant derivatives of β-galactosidase from Thermus sp. (strain t2) fused with polyhistidine tails (imac/?-galactosidase) and cloned in E. coli CECT 5970. The inventive method is suitable for use in the dairy industry and in biotechnology where it is applied to different milk derivatives, such as milk, whey or any other compound comprising lactose, in order to prevent intolerance problems and...

Filing Date: 2003-01-24.--Priority Data: ES (2002-01-24) (P200-20-01), The invention relates to a nucleic acid sequence comprising the RNA packaging signal of a group 1 coronavirus, such as transmissible gastroenteritis virus of swine (TGEV), which is located between nucleotides 100 and 649 of the genome of said coronavirus. The inventive sequence can be employed to produce viral vectors for use in basic and applied research, for example, in developing systems of expressing products of interest, vaccine vectors and gene therapy.

Filing Date: 2002-05-03.-- Priority Data: ES (2001-05-14)P- (2001-01-09), The invention relates to a method for extracting the gluten contained in a sample consisting in using an ethanol aqueous solution in the presence of a composition containing a disulphur group reducer and a decoupling agent, in a buffer having a pH of between 7 and 8. The inventive method can be used to extract quantitatively the gluten contained in a heat-processed or non-heat-processed food sample before the quantification of the gluten by ELISA. Said method is suitable for food analyses, in..., Peer reviewed

Filing Date: 2003-10-24.-- Priority Data: ES P200202509 (2002-10-31), The invention relates to novel mesoporous aluminosilicate-type materials having a chemical composition with the following formula (in oxide moles): Al2O3: m SiO2: n M2O, wherein: m denotes a value of between 10 and 1000, preferably between 20 and 200; M denotes cations Na+ or H+; and n denotes a value of between 0.001 and 1, preferably between 0.01 and 1. The inventive materials comprise regularly-distributed pores having an average diameter of between 2 and 10 nm. Moreover, said materials also...

Filing Date: 2003-05-20.-- Priority Data: ES (2002-06-04)P- (2002-01-27), The invention relates to a method of preparing a frozen, battered food product. The inventive method consists in, first, flouring the food product to be battered and applying a reconstituted batter to the floured food product, said batter containing a cellulose derivative which coagulates in a bath of hot water in the presence of water vapour. The battered food product is subsequently heated and coagulated using a standard infrared or microwave oven, such that the layer of coagulated batter..., La presente invención se refiere a un nuevo proceso para la preparación de un alimento rebozado y congelado, proceso cuyo objetivo fundamental es eliminar la clásica etapa de prefritura en aceite de los alimentos, realizada en el proceso de elaboración equivalente y convencional.

Filing Date: 2006-05-11.-- Priority Data: ES (2005-05-11) (P200-50-11), [EN]The invention relates to a method of fixing carbon dioxide (CO2) by cultivating any halotolerant nitrogen-fixing cyanobacterium which can produce an exopolysaccharide that is excreted to the medium. The inventive method can be used to reduce or eliminate CO2 emissions from industrial processes, such as from electrical power plants. The invention also relates to the biofuel use of an exopolysaccharide that is produced from the cultivation of cyanobacterium Anabaena which has a high calorific..., [ES]El objeto de la presente invención es un proceso para fijar dióxido de carbono (COz), mediante el cultivo de cualquier cianobacteria fijadora de nitrógeno, halotolerante, y capaz de producir un exopolisacárido que se excreta al medio. La utilización de dicho procedimiento permite reducir o eliminar emisiones de COz que proceden de procesos industriales, por ejemplo de las centrales O de generación eléctrica. Otro objeto de la presente invención lo constituye la utilización como...

Filing Date: 2006-01-12.-- Priority Data: ES (2005-01-12) (P200-50-00), [EN]The invention relates to nucleic acids and allergens of olive tree pollen of defined olive tree varieties and to the applications thereof. Nucleic acids that encode peptides or fragments of same have been isolated, characterised and identified, said nucleic acids comprising at least one epitope of allergen Ole e 1 or of allergen Ole e 2 of olive tree pollen of defined olive tree varieties. Said peptides, which possess one or more allergenic epitopes of the major allergens of olive tree..., [ES]Se han aislado, caracterizado e identificado ácidos nucleicos que codifican péptidos, o fragmentos de los mismos,que comprenden, al menos, un epítopo del alérgeno Ole e 1 o del alérgeno Ole e 2 de polen de olivo de variedades definidas de olivo. Dichos péptidos, que poseen uno o más epítopos alergénicos de los alérgenos mayoritarios del polen de olivo tienen actividad alergénica y pueden ser utilizados en el diagnóstico y tratamiento de la alergia al polen de olivo. La actividad alergénica...

Filing Date: 2003-06-20.--Priority Data: ES P200201436 (2002-06-21), The invention relates to a therapeutic compound against Leishmania infection and to the use thereof. Said invention has for the first time demonstrated the role of the DC-SIGN (Dendritic cell-specific ICAM 3 grabbing non-integrin) receptor, which is present on the surface of dendritic cells, in the process of binding the Leishmania parasite to human eukaryotic cells, among others, dendritic cells, macrophages and cells derived from monocytes. The invention relates to a novel therapeutic...

Filing Date: 2002-05-10.-- Priority Data ES P200101133 (2001-05-18)., [EN] The invention relates to a DNA molecule or a fragment of said DNA molecule obtained from the LCR (Locus Control Region) sequence of the mouse tyrosinase gene. Said sequence has insulating activity against chromosomal position effects in gene transfer processes in animal cells. The DNA molecule can be used to introduce transgenes and to reduce the variability of the transgene expression in animal cells., [ES] Molécula de ADN o un fragmento de la misma obtenida a partir de la secuencia LCR (Locus Control Region) del gen de la tirosinasa de ratón. Dicha secuencia tiene actividad aisladora de efectos de posición cromosomales en procesos de transferencia génica en células de animales. La molécula de ADN puede utilizarse para introducir transgenes y reducir la variabilidad de la expresión de transgenes en células de animales.

Filing Date: 2000-12-12, The invention relates to a system for organizing n-dimensional data in a representation of a smaller dimension in a non-linear and non-supervised manner. The types of methods presented herein are commonly known as self-organizing maps and resemble, but are not identical to, the well known Kohonen's self-organizing maps. The basic idea of the invention consists of a combination of data clustering and soft projection thereof in a space of a smaller dimension (usually a bidimensional mesh)....

Filing Date: 2002-03-07., The invention relates to the modulation of apoptosis in mammalian cells. More particularly, the invention provides methods for identifying novel pro-apoptotic or anti-apoptotic cellular polypeptides, methods of screening compounds which modulate apoptosis, and method of detecting early events of the apoptotic process.

Filing Date: 2000-07-17.-- Priority Data: GB 9916810 (1999-07-16)., The present invention relates to killing cells, or at least impeding cell cycle progression. More particularly it relates to methods and means for attacking eukaryotic cells, such as tumour cells, with cytostatic, cytotoxic and/or cytopathic agents. Specifically, the present invention employs the ParD kid toxin and ParD kis antitoxin under appropriate control for selective cell cycle inhibition and/or killing of target cells.

Filing Date: 2005-12-15.-- Priority Data: ES P 200402994 (2004-12-16)., The invention relates to a method of producing industrially-viable prebiotic oligosaccharides using a novel enzyme of Xanthophyllomyces dendrorhous, which is characterised by having α-glucosidase activity. The invention also relates to a method of obtaining an enzymatic product with α-glucosidase activity and the substantially-pure enzyme with α-glucosidase activity. The enzymatic product and the enzyme offer the advantage of having a high performance spectrum and a high specific activity. Said...

Filing Date: 2004-07-19. Priority Data: GB 0316882.0 (2003-07-18), The present invention is based on the capacity of the Olfactory Ensheathing Glia (OEG) to foster axonal regeneration in the adult mammalian central nervous system (CNS). This specific capacity is probably due to a combination of several factors, such as the molecular composition of cellular membrane and/or the capacity to secrete some molecules; combined with the capacity to reduce glial scar and accompany new growing axon in the damaged CNS. We have developed immortalised cell lines from...

Filing Date: 2005-10-27.-- Priority Data ES P200402605 (2004-10-28), The invention relates to a biosensor which is obtained by immobilising peptide nucleic acid (PNA) molecules onto gold surfaces and to the uses thereof in the detection and characterisation of nucleic acid molecules (DNA or RNA) of biosanitary, environmental and dietary interest. The method of constructing said biosensors is based on the fact that PNA molecules can be immobilised in a controlled manner with one end thiolated onto monocrystalline or polycrystalline gold surfaces, such as to...

Filing Date: 2005-07-27.--Priority Data: ES P200401878 (2004-07-29), The invention relates to a digital system (1) for performing stereotaxic biopsies with a biopsy needle. The inventive system (1) comprises a series of devices which are used to: emit X-rays, detect and transform X-ray photons into electric signals, position a tissue sample between the X-ray source and the detector, process the electric signals, and generate images. The system can also be equipped with a series of devices complementary to those mentioned above, as well as a means for positioning...

Filing Date: 2005-02-01.--Priority Data ES (2004-02-09) (P200-40-02), [EN] The invention relates to a method and device for measuring hydridation kinetics at different temperatures in tubular industrial components. The invention consists in measuring the power dissipated by a hydridation reaction over time as well as the variation in the electric resistance during said reaction. The inventive method and device can be used to optimise industrial components, such as tubes and fuel claddings for nuclear reactor cores. In this way, safety is increased, with the..., [ES] Procedimiento y dispositivo para medir cinéticas de hidruración a diferentes temperaturas en componentes industriales tubulares. Se mide la potencia disipada por la reacción de hidruración en el transcurso del tiempo Se mide igualmente la variación de la resistencia eléctrica durante dicha reacción. El uso de dicho procedimiento y dispositivo permite la optimización de componentes industriales como tubos y vainas de combustible para los núcleos de los reactores nucleares. Así se eleva la...

Filing Date: 2003-08-06.--Priority Data: ES P200201895 (2002-08-09), The invention relates to bacteria that can overproduce and secrete proteins. In one form of the invention, the extracellular protease activity of the Streptomyces lividans strain is greatly reduced and, as a result, the stability of the proteins in the extracellular medium increases over time.

Filing Date: 2003-07-10.--Priority Data: ES P200201776 (2002-07-26), The invention relates to multifunctional genetic constructions which can mimic the HIV-1-resistant phenotype in individuals with mutations that functionally inactivate the CCR5 chemokine receptor. In this way, the invention relates to various therapeutic genetic constructions which can inhibit specifically the expression of the aforementioned receptor in human cells and to retroviral vectors which can be used to introduce therapeutic genes into said cells. Moreover, the invention relates to a...

Filing Date: 2003-07-02.--Priority Data: ES P200201553 (2002-07-03), The invention relates to genetic constructions comprising genes that code a cytotoxin, cytotoxic peptide ζ and the antidote e thereof. The invention also relates to the use of the aforementioned constructions for the transformation of micro-organisms used in biotechnological processes that require an active biological containment system, in order to eliminate released genetically-altered micro-organisms for the purpose of improving cultures, protecting plants and crops, cleaning up the...

Filing Date: 2002-12-31.--Priority Data: US 60/343,222 (2001-12-31), The present invention permits data, derived from bGH-Tg mice in the context of crosstalk between cytokine and chemokine responses, to aid in understanding the functional role of this chemokine/chemokine receptor pair. As the only models available to date were thoses in which the CXCR4 or CXCL12 deletion is lethal before birth the present invention provides means for relating cytokine-mediated effects to the functional role of CXCR4 inactivation in postanatal life. A method is provided for...

Filing Date: 2002-03-14.-- Priority Data: ES P200100618 (2001-03-16), The invention relates to the selection of a mushroom, Ophiostoma piceae, which secretes a commercial esterase. The invention also relates to the production and characterisation of the enzyme and the application tests carried out on synthetic process liquids and pulps representative of paper pulp production processes using hardwood and softwood. The results obtained demonstrate that the novel enzyme possesses great affinity and activity in relation to cholesterol linoleate, oleate, tributyrin...

Filing Date: 1997-10-01.-- Priority Data: ES 9602091 (1996-10-04).-- International Publication Number: WO_98015640 (19980416), The process refers to highly selective enzymatic production of monosaccharides and mono-polyols and/or disubstitued with fatty acids. The procedure is based on the simple mixture of polyol or monosaccharide with the fatty acid, the addition of solvent, and the use of lipases that permit the highly selective obtainment of these products without catalysts or toxic agents. The water produced during the process must be continuously removed throughout the same. The invention belongs to the...

Filing Date: 1995-12-28., The invention discloses a process for producing coatings of various oxides by using the sol-gel method and the technics of immersion and spraying on silver coatings and substrates. Said process provides for the preparation of coatings of various compositions, vitreous or polycrystalline, and which have an excellent homogeneity, high adherence and good mechanical and thermal compatibility with the metal substrate. Said coatings result in an efficient barrier against dry oxidation at high..., Peer reviewed

Filing Date: 1996-06-28.-- Priority Data ES P9501419 (1995-07-14), The present invention relates to the production of solid state lasers of dyes of the family of rodamines. More specifically, it relates to lasers wherein said dye or chromophor is covalently anchored to a solid matrix, and comprises an organic polymer which is transparent and sufficiently stable to the pumping radiation. Application to the production of laser emission by means of an organic dye in a solid matrix and polymers containing rodamines.

Filing Date: 1996-07-12.-- Priority Data: ES P 9501420 (1995-07-14) ES P 9501858 (1995-09-26) ES P 9600941 (1996-04-25), Hydrometallurgical process for the recovery of copper from oxidized metal materials through lixiviation with an aqueous solution which contains ammonium ions (which is provided to the system as ammonium hydroxide, ammonium carbonate and/or ammonium chloride), and which provides for the formation of ammoniated copper complexes (II), and removal of the copper from the fertile solution obtained by solvent extraction (using acid agents for the extraction), the lixiviation solution being regenerated...

Filing Date: 1996-02-08.-- Priority Data ES P 9500269 (1995-02-09), The invention provides for the rapid and simple selection of fragments of DNA amplified by a non specific PCR reaction, fragments which are then used as specific probes of strain or specie, as desired. The fragments extracted from an agarose gel will be used as a probe in a hybridation on a solid medium whereon DNA samples have been immobilized, whether amplified or not, of bacterial strains to be identified. With the disclosed process it is possible to obtain specific probes applicable to the...

Filing Date: 1996-02-08.-- Priority Data: ES P 9500265 (1995-02-09), Surfactants having general formula (II) wherein x = 8-14; n = 2-8. The process for obtaining such surfactants comprises the following steps: a) producing nitroarginin; b) producing N'alpha'-acil-nitroarginin; c) producing N'alpha',N'omega',bis(N'alpha'-acil-arginin-'alpha''omega' diaminoalkylamide dichlorohydrate. Said surfactants are antimicrobial agents which can be applied to cosmetics, pharmacy and food industry.

Derwent Primary Accession number: 2004-146321, The aluminum powder stabilization comprises collection in bags of the powder carried over in slag grinding and grading operations. The powder is then mixed with gypsum to permit controlled storage in the form of solid blocks. The gypsum forms dihydrate, without decrease in the metallic aluminum, aluminum nitride and sulfur concentrations, in comparison with hydrolysis in water. The hydrolysis gas is trapped, to prevent damage to the environment., Peer reviewed

Derwent Primary Accession Number: 2003-481996 International Application No.: PCT/ES2002/000507, [EN] The invention relates to a method for the partial recovery of a filtration adjuvant used in methods of extracting polysaccharides from algae. The inventive method essentially consists in: drying the residue in order to eliminate the majority of water; heating the dried product at a temperature of between 500 and 900 °C; and combusting the gases originating from the pyrolysis of the organic material. In a first variation, the dried product is heated in a fluidised bed furnace at a..., [ES] Procedimiento de recuperacion parcial de un coadyuvante de filtracion utilizado en los procesos de extraccion de polisacaridos a partir de algas, que comprende, fundamentalmente, la siguiente secuencia de operaciones ; seccado del residuo para eliminar la mayor parte del agua, calentamiento del producto seco entre 500 900 °C, y combustion de los gases procedentes de la pirolisis de la materia organica. En una primera variante el calentamiento del producto seco se realiza en un horno de..., HISPANAGAR, S.A., Peer reviewed

Filing Date: 2006-05-24.--Priority Data: EP 05076219.4 (2005-05-24), The invention relates to animal solid tumour models which comprise a transgenic non-human mammal containing in its genome a DNA construct that comprises a gene created and/or activated by a genetic anomaly associated with human cancer operatively bound to a promoter that directs the expression of the gene in Scal+ cells. The invention also relates to stem cells capable of specifically expressing in stem cells human genetic anomalies associated with human pathologies. Applications of these..., Peer reviewed

Filing Date: 2005-11-18.-- Priority Data: CA 2,488,113 (2004-11-18), The present invention relates to the field of diseases, such as Alzheimer's disease, where abnormal brain accumulation of ß amyloid and/or amyloid plaques are involved. More specifically, the present invention relates to a non-human animal model for such diseases and its use in screening methods for molecules for treating same.

Filing Date: 2003-10-01.-- Priority Data: ES (2002-10-01) (P200-20-22), The invention relates to a device which is used intra-operatively to localise carcinogenic tumours and ganglia precisely and in a three-dimensional manner and to correlate the surgical instruments with the images in real time. The structural elements of the functional navigator include: a surgical navigator, a camera which is used to obtain functional images, the position-finding elements of the camera and the surgical instruments and the specific software program which combines all of the...

The invention relates to an immunochromatography system comprising two immunochromatographic sticks or strips which enable the simultaneous identification of different antibodies in a biological sample from patients with celiac disease (CD), which are specific to the autoantigens that are characteristic of CD as well as AGA (antigliadin antibodies) and t-TG (tissue transglutaminase). The invention also relates to a method of identifying antibodies present in patients with CD, which is based on..., Filing Date: 2003-08-14.-- Priority Data: ES P200201939 (2002-08-16)

Filing Date: 2003-07-07.-- Priority Data: ES P200201702 (2002-07-19), The invention relates to a method for the production of natural or synthetic zeolite monoliths, using other silicates as additives which provide rheological properties that enable extrusion moulding of honeycomb-type structures. The mechanical properties of the monoliths obtained are stabilised by means of hydrothermal treatment with sodium silicate solutions. The product thus obtained is a honeycomb-type monolith which retains the physical and chemical properties of the zeolite contained...