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Clinical Characteristics of Asymptomatic and Symptomatic Pediatric Coronavirus Disease 2019 (COVID-19): A Systematic Review.

Repositorio: r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Yoon S, Li H, Lee KH, Hong SH, Kim D, Im H, Rah W, Kim E, Cha S, Yang J, Kronbichler A, Kresse D, Koyanagi A, Jacob L, Ghayda RA, Shin JI, Smith L

Background and objectives: Characterization of pediatric coronavirus disease 2019 (COVID-19) is necessary to control the pandemic, as asymptomatic or mildly infected children may act as carriers. To date, there are limited reports describing differences in clinical, laboratory, and radiological characteristics between asymptomatic and symptomatic infection, and between younger and older pediatric patients. The objective of this study is to compare characteristics among: (1) asymptomatic…



Metabolic and Functional Improvements in a Patient with Charcot-Marie-Tooth Disease Type 2 after EGCG Administration: A Case Report

Repositorio: r-FISABIO: Repositorio Institucional de Producción Científica
Bustos, A, Sabater, P, Benlloch, M, Drehmer, E, Lopez-Rodriguez, M, Platero, F, Platero, J, Escriba-Alepuz, J, Orti, J

Background and objectives: The aim of this study was to report a case of a patient with Charcot-Marie-Tooth disease type 2 (CMT2) treated with epigallocatechin gallate (EGCG) for 4 months in order to assess its therapeutic potential in CMT2. Materials and Methods: The study included a brother and a sister who have CMT2. The sister received 800 mg of EGCG for 4 months, while her brother received placebo for the same period of time. Both participants were assessed before and after daily…



Relation between Alpha-Synuclein and Core CSF Biomarkers of Alzheimer's Disease.

Repositorio: r-FISABIO: Repositorio Institucional de Producción Científica
Monge-García V, García-Ayllón MS, Saez J, Sánchez-Payá J, Navarrete-Rueda F, Manzanares-Robles J, Gasparini-Berenguer R, Romero-Lorenzo R, Cortés-Gómez MA, Monge-Argilés JA

Background: Alzheimer's disease (AD) is characterized by the presence of ß-amyloid plaques and neurofibrillary tangles, while Lewy body dementia (LBD) is characterized by a-synuclein (a-syn) inclusions. Some authors examine a-syn protein in the neurodegeneration process of AD and propose to consider cerebrospinal fluid (CSF) a-syn as a possible additional biomarker to the so-called "core" of AD. Objective: To determine whether there is a correlation between a-syn levels and…