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Metabolic and Functional Improvements in a Patient with Charcot-Marie-Tooth Disease Type 2 after EGCG Administration: A Case Report

Repositorio: r-FISABIO: Repositorio Institucional de Producción Científica
Bustos A, Sabater P, Benlloch M, Drehmer E, Lopez-Rodriguez M, Platero F, Platero J, Escriba-Alepuz J, Orti J

Background and objectives: The aim of this study was to report a case of a patient with Charcot-Marie-Tooth disease type 2 (CMT2) treated with epigallocatechin gallate (EGCG) for 4 months in order to assess its therapeutic potential in CMT2. Materials and Methods: The study included a brother and a sister who have CMT2. The sister received 800 mg of EGCG for 4 months, while her brother received placebo for the same period of time. Both participants were assessed before and after daily…



Clinical Characteristics of Asymptomatic and Symptomatic Pediatric Coronavirus Disease 2019 (COVID-19): A Systematic Review.

Repositorio: r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Yoon S, Li H, Lee KH, Hong SH, Kim D, Im H, Rah W, Kim E, Cha S, Yang J, Kronbichler A, Kresse D, Koyanagi A, Jacob L, Ghayda RA, Shin JI, Smith L

Background and objectives: Characterization of pediatric coronavirus disease 2019 (COVID-19) is necessary to control the pandemic, as asymptomatic or mildly infected children may act as carriers. To date, there are limited reports describing differences in clinical, laboratory, and radiological characteristics between asymptomatic and symptomatic infection, and between younger and older pediatric patients. The objective of this study is to compare characteristics among: (1) asymptomatic…



Relation between Alpha-Synuclein and Core CSF Biomarkers of Alzheimer's Disease.

Repositorio: r-FISABIO: Repositorio Institucional de Producción Científica
Monge-García V, García-Ayllón MS, Sáez-Valero J, Sánchez-Payá J, Navarrete-Rueda F, Manzanares-Robles J, Gasparini-Berenguer R, Romero-Lorenzo R, Cortés-Gómez MA, Monge-Argilés JA

Background: Alzheimer's disease (AD) is characterized by the presence of ß-amyloid plaques and neurofibrillary tangles, while Lewy body dementia (LBD) is characterized by a-synuclein (a-syn) inclusions. Some authors examine a-syn protein in the neurodegeneration process of AD and propose to consider cerebrospinal fluid (CSF) a-syn as a possible additional biomarker to the so-called "core" of AD. Objective: To determine whether there is a correlation between a-syn levels and…



Mediterranean Diet Adherence and Eating Disorders in Spanish Nurses with Shift Patterns: A Cross-Sectional Study.

Repositorio: r-FISABIO: Repositorio Institucional de Producción Científica
Leyva-Vela B, Reche-Garcia C, Hernandez-Morante J, Martinez-Olcina M, Miralles-Amoros L, Martinez-Rodriguez A

Background and Objectives: Shift work has a significant influence on the mental health of workers. Nursing is characterised by a rotational work system. This study aimed to determine whether there was a link between adherence to the Mediterranean diet (MD) and the risk of suffering an eating disorder (ED) in nurses according to their work shift. Materials and Methods: A total of 240 women (nurses and nursing assistants) were evaluated and completed the PREDIMED-PLUS questionnaire on…



Fracture Resistance of New Metal-Free Materials Used for CAD-CAM Fabrication of Partial Posterior Restorations

Repositorio: r-INCLIVA: Repositorio Institucional de Producción Científica de la Fundación para la Investigación del Hospital Clínico de la Comunidad Valenciana
Garcia-Engra G, Fernandez-Estevan L, Casas-Terron J, Fons-Font A, Castelo-Baz P, Agustin-Panadero R, Roman-Rodriguez J

Background and Objectives: To evaluate in vitro the fracture resistance and fracture type of computer-aided design and computer-aided manufacturing (CAD-CAM) materials. Materials and Methods: Discs were fabricated (10 x 1.5 mm) from four test groups (N = 80; N = 20 per group): lithium disilicate (LDS) group (control group): IPS e.max CAD(R); zirconium-reinforced lithium silicate (ZRLS) group: VITA SUPRINITY(R); polymer-infiltrated ceramic networks (PICN) group: VITA ENAMIC(R); resin…



Eating Disorders in Pregnant and Breastfeeding Women: A Systematic Review.

Repositorio: r-ISABIAL: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
Martínez-Olcina M, Rubio-Arias JA, Reche-García C, Leyva-Vela B, Hernández-García M, Hernández-Morante JJ, Martínez-Rodríguez A

Background: Pregnancy is a stage associated with various biopsychosocial changes. These changes, along with concerns about keeping an adequate weight, can modulate an individual's risk for psychological disorders, especially eating disorders (EDs). The aim of this review was to investigate the prevalence, associated risks, and consequences of eating disorders in pregnancy and in breastfeeding mothers. Materials and Methods: A systematic review was carried out following the PRISMA…



Mediterranean Diet Adherence and Eating Disorders in Spanish Nurses with Shift Patterns: A Cross-Sectional Study

Repositorio: r-ISABIAL: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
Leyva-Vela B, Reche-Garcia C, Jose Hernandez-Morante J, Martinez-Olcina M, Miralles-Amoros L, Martinez-Rodriguez A

Background and Objectives: Shift work has a significant influence on the mental health of workers. Nursing is characterised by a rotational work system. This study aimed to determine whether there was a link between adherence to the Mediterranean diet (MD) and the risk of suffering an eating disorder (ED) in nurses according to their work shift. Materials and Methods: A total of 240 women (nurses and nursing assistants) were evaluated and completed the PREDIMED-PLUS questionnaire on…



Relation between Alpha-Synuclein and Core CSF Biomarkers of Alzheimer's Disease

Repositorio: r-ISABIAL: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
Monge-Garcia V, Garcia-Ayllon M, Saez-Valero J, Sanchez-Paya J, Navarrete-Rueda F, Manzanares-Robles J, Gasparini-Berenguer R, Romero-Lorenzo R, Cortes-Gomez M, Monge-Argiles J

Background: Alzheimer's disease (AD) is characterized by the presence of beta-amyloid plaques and neurofibrillary tangles, while Lewy body dementia (LBD) is characterized by alpha-synuclein (alpha-syn) inclusions. Some authors examine alpha-syn protein in the neurodegeneration process of AD and propose to consider cerebrospinal fluid (CSF) alpha-syn as a possible additional biomarker to the so-called "core" of AD. Objective: To determine whether there is a correlation between…