BUSCADOR RECOLECTA

Este articulo presenta el surgimiento de la educación inclusiva en el ámbito de la Educación Especial, las causas que la han promovido y la necesidad de reformar los sistemas educativos y las prácticas escolares para hacerla realidad. Con este fin se revisa lo acontecido en el desarrollo del movimiento de la integración escolar, los efectos negativos ocasionados por el modelo del déficit y la necesidad de desarrollar políticas inclusivas nacionales y sistemas de apoyos locales que promuevan la…

Las plaquetas juegan un papel crítico en el inicio, progreso y resultado de los síndromes coronarios agudos. La activación indeseada que sufren estas células es una de las principales razones para que aparezcan complicaciones clínicas. Esta activación implica la actuación coordinada de miles de proteínas conectadas mediante rutas de señalización intracelular. El objetivo de esta tesis era investigar los mecanismos moleculares que gobiernan la acción de las plaquetas durante los eventos agudos y…

This essay deals with the confrontation between universalistic and particularistic principles with regard to collective identities and nationalities in the Third World. Universalistic principles are based on the 18th century rationalism; its most important representative in the field of comparative world history was the Marquis of Condorcet. This current makes no difference between natural and social sciences and does not care for national singularities. Particularistic tendencies are based on…

El presente artículo forma parte de un adelanto del proyecto de investigación denominado Espacio público, participación y militarismo, financiado por la Universidad del Zulia en Venezuela. Se plantea a través de una visión transdisciplinaria una aproximación a las características sociales, políticas e ideológicas del discurso del poder emitido por Hugo Chávez, como actor político hegemónico en el proceso contemporáneo en Venezuela. Se identifican las principales áreas temáticas contenidas en su…

Las características de las redes sociales y la comunicación en Internet son un gran reto para las organizaciones que buscan promover la participación ciudadana en temas relacionados al medio ambiente, especialmente en México. El calentamiento global y otros problemas medioambientales son en el siglo XXI, probablemente la mayor amenaza que enfrenta a la humanidad. En la actualidad, el gran avance en tecnologías de información y comunicación y el aumento de la penetración de Internet en la…

En los últimos años un renovado interés por el andaluz Luis Vélez de Guevara ha permitido arrojar nueva luz sobre diferentes aspectos de su vida y obra, rescatándolo del peligroso e injustificado olvido al que se le había relegado durante mucho tiempo, a partir sobre todo del siglo XIX. Vélez, autor del «rumbo, el tropel, el boato» de los que hablara Cervantes en el prólogo a sus Ocho comedias y ocho entremeses (1998: 93), fue considerado a menudo como el dramaturgo que «gusta[ba] mucho de la…

A presente investigación pretende achegar ao lector a realidade xornalística dos medios de comunicación locais da Comarca de Lemos, a través das aparicións das manifestacións populares tradicionais deste territorio na súa prensa local. Extraéronse interesantes conclusións sobre as rutinas produtivas no proceso xornalístico e o peso das tradicións populares tradicionais na axenda temática dos medios, así como a fidelización dos lectores a través da identificación coa comunidade e o medio, todo…

[ES]La Cohors I Celtiberorum es una de las unidades auxiliares hispanas con mayor número de menciones en la documentación epigráfica. Ello ha provocado la aparición de no pocos trabajos en los que se ha tratado de reconstruir su evolución a lo largo del tiempo. Nosotros pretendemos ahora revisar todas esas antiguas y controvertidas informaciones (epigráficas y textuales, principalmente) y añadir nuevos datos provenientes de la práctica arqueológica a fin de aclarar definitivamente la naturaleza…, [EN]The Cohors I Celtiberorum is a Spanish auxiliary unit present in many ancient epigraphical documents. Some scholars had tried to rebuild unit’s history, but only picking that old and controversial data (mostly epigraphical and textual). Our objective is to review both their work and data and to add new archaeological information in order to understand the nature and deployment of the unit under the Roman Empire, Bolsas FPU. Ministerio de Ciencia e Innovación

This doctoral thesis studies times series methods for different industrial applications in two fields: i) Structural Health Monitoring (SHM): the aim is to develop methods to assess the health of a structure (if it has damage or not, location of the damage) including some extensions to changing environmental conditions and identification/localization of the damage. Several methods parametric and non–parametric have been analyzed. The proposed methods have been validated in lab–scale wind…

Time series interpretation aims to provide an explanation of what is observed in terms of its underlying processes. The present work is based on the assumption that the common classification-based approaches to time series interpretation suffer from a set of inherent weaknesses, whose ultimate cause lies in the monotonic nature of the deductive reasoning paradigm. In this thesis we propose a new approach to this problem, based on the initial hypothesis that abductive reasoning properly accounts…

During this project a new theoretical method will be developedin order to obtain accurate partition functions for molecular systems that present two internal rotations.Such method will be applied to a bunch of different molecules and the results will be thoroughly analyzed and compared with those obtained with the other methods available such as Pitzer-Gwinn, Ayala-Schlegel or Chuang-Truhlar. The convenience of the application of the different methods (one dimensional methods will also be…

Fue en 1951 cuando se inicia la radiocirugía, que consiste en aplicar una dosis de radiación alta y única en un volumen tumoral pequeño. En el año 2004, se empezaron a tratar pacientes en el CHUS con diferentes patologías mediante esta técnica. Hacemos un estudio retrospectivo descriptivo de una serie de 98 pacientes diagnosticados de schwannoma del nervio vestibular tratados mediante radiocirugía empleando un acelerador lineal (LINAC). Exponemos nuestra metodología, estudiamos el control…

Partially supported by Xunta de Galicia (Spain), project EM2014/032, SI

Hace ahora algo más de un siglo, el sueco Svante Arrhenius señaló que el aumento de la concentración de dióxido de carbono en la atmósfera, debido a la actividad humana, terminaría produciendo un calentamiento global del planeta. Arrhenius reconoció en su estudio de 1896, las contribuciones hechas anteriormente para la comprensión del efecto invernadero por el matemático francés Jean-Baptiste Fourier, que se remontan a 1827. Sin embargo, no era la intención de Arrhenius el pronosticar ninguna…

La regulación de la homeostasis energética constituye en realidad un complejo proceso en el que están implicados diversos componentes tanto de origen central (hipotálamo), como hipofisario y periférico (tejido adiposo, estómago, hígado, páncreas, gónadas, etc.) que, en conjunto, forman un circuito regulador integrado. En la búsqueda de la comprensión de esos circuitos han ido apareciendo nuevos candidatos objetos de estudio como: NR4A, que es una subfamilia de receptores nucleares huérfanos,…

El presente estudio analiza el estrés percibido y el ajuste psicológico de militares que participan en misiones internacionales mediante un estudio prospectivo en el que se les ha evaluado en tres momentos temporales durante una misión de seis meses de duración. Los resultados muestran un aumento del estrés percibido a la llegada a zona de operaciones que se mantiene estable a lo largo del despliegue y esta asociado con un peor ajuste psicológico. Respecto a la salud mental, se produce un…

En La enseñanza del inglés en Educación Infantil: análisis de buenas prácticas educativas, se lleva a cabo un estudio de la situación de la docencia de la lengua inglesa en la etapa de Educación Infantil en la Comunidad Autónoma de Galicia a través de la recopilación de información en 40 centros. La intención de este estudio es analizar la metodología que los especialistas emplean en las sesiones didácticas de modo que se puedan identificar las estrategias de enseñanza óptimas así como la…

Acinetobacter baumannii es un importante patógeno nosocomial Gram-negativo de especial interés debido a su habilidad para generar multirresistencias a antibióticos y a su formidable capacidad de supervivencia en forma de biopelículas, causando un gran número de infecciones humanas. Entre los mecanismos de virulencia de A. baumannii, destacan la motilidad y la formación de biopelícula, fenotipos controlados mediante una red compleja de factores donde se encuentra el sistema de comunicación…

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In the theory of simple games, the study of power indices plays an important role. One of the main di culties with these indices is that computation generally requires the sum of a very large number of terms. The generating functions are e cient tools to make more easy this computation. In this paper, we provide a revision of the main elements of this method when we use it to compute the Shapley-Shubik and the BanzhafColeman power indices. Further, we provide a new method to compute the Banzhaf…, SI

Texto dispoñible en galego e español, A contorna globalizada e moito máis competitiva na que operan as empresas na actualidade provocou que estas deban buscar estratexias que lles permitan afrontar con éxito os retos que se lles presentan. Así, hoxe en día a calidade converteuse nunha das variables clave de competitividade que as empresas galegas deben incorporar á súa estratexia corporativa. O propósito do noso traballo é estudar o grao de implantación da calidade/xestión da calidade nas empresas galegas, para o que imos realizar…, El entorno globalizado y mucho más competitivo en el que operan las empresas en la actualidad ha provocado que estas deban buscar estrategias que les permitan afrontar con éxito los retos que se les presentan. Así, hoy en día la calidad se ha convertido en una de las variables clave de competitividad que las empresas gallegas deben incorporar a su estrategia corporativa. El propósito de nuestro trabajo es estudiar el grado de implantación de la calidad/gestión de la calidad en las empresas…, The global environment and much more competitive in the one that operate the companies, it has caused that these they should look for strategies that allow them to confront with success the challenges that are presented, the quality he/she has become this way today day in one of the key variables of competitiveness that the Galician companies should incorporate to their corporate strategy. The purpose of our work is to study the grade of installation of the Quality/Administration of the Quality…, SI

In the era of personalized medicine, the rational design of nanosystems has become a key element to provide more effective and powerful treatments in cancer therapy. This thesis disclosed a new nanoplatform, based on sphingomyelin in combination with an oil, which is simple in composition, easy to produce, stable, biocompatible, highly versatile and suitable for the association of different drugs and molecules. An in silico-in vitro approach has allowed us to gather extensive knowledge…

We study the stability of Catalan and Spanish coexistence in Catalonia, a key political and economic European region. Recent, abundant empirical data of language use is analyzed within an analytic model of population dynamics. This model contemplates the possibilities of both long-term language coexistence and decline. The data needs to be interpreted under different circumstances. The most likely scenario, we find, is a sustained coexistence. Extreme cases still lead to the decline of one of…, This work was partially funded by the Galician Royal Academy (Real Academia Galega), SI

La actividad minera existente en las montañas limítrofes entre las comunidades autónomas de Galicia y Castilla y León se ha mostrado fundamental para producir riqueza y mantener así una población relativamente abundante en un espacio en principio poco atractivo, donde conviven la minería del carbón, en grave crisis, y la de la pizarra, en fase expansiva. En ambos casos el resultado demográfico ha sido el mismo: concentración de los efectivos humanos en los núcleos rectores de Ponferrada, O…, L'ardoise et le charbon dans les montagnes entre la Galice et León.- L'activité minière existante dans les montagnes limitrophes des Communautés autonomes de la Galice et de Castilla y León s'est montrée fondamentale pour produire richesse et maintenir ainsi une population relativement abondante dans un espace en principe peu attrayant, où coexistent l'extraction du charbon, qui connaît une grave crise, et celle de l'ardoise, en phase expansive. Dans les deux cas le…, The slate and the coal in the mountains between Galicia and León.- The mining industry developed in the mountainous limit between the Galicia and Castilla y León autonomous regions has been essential to produce wealth and thus to keep a relatively abundant population into a space with a weak initial attraction. There the declining charcoal extraction coexists with the expansive slate industry, but in both cases the demographic result has been the same: a concentration of the population figures…, SI

This is an Accepted Manuscript of an article published by Thieme Publishing Group in Thrombosis and Haemostasis on 04 January 2020, available online at https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0039-3400295, C-type lectin-like receptor 2 (CLEC-2) plays a crucial role in different platelet-related physiological and pathological processes. It signals through a tyrosine kinase-mediated pathway that is highly dependent on the positive feedback exerted by the platelet-derived secondary mediators, adenosine diphosphate (ADP) and thromboxane A2 (TXA2). Here, we aimed to analyze the tyrosine phosphoproteome of platelets activated with the CLEC-2 agonist rhodocytin to identify relevant phosphorylated…, This study was supported by the Spanish Ministry of Economy and Competitiveness (MINECO) [grant No. SAF2016-79662-R], co-funded by the European Regional Development Fund (ERDF); and the Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia [ED431C 2018/21; predoctoral grant Plan I2C 2014; and Centro Singular de investigación de Galicia accreditation 2016-2019, ED431G/05], co-funded by the European Regional Development Fund (ERDF). The study also received funding from…, SI

A non-targeted strategy to simultaneously screen for over 100 lipid mediators from ω-6 ARA and ω-3 EPA and DHA fatty acids is presented. The method based on an extensive study of fragmentation patterns obtained by SPE-LC-MS/MS analysis-provided fingerprints to comprehensively elucidate and identify lipid mediators in biological samples. Many of these metabolites are associated to metabolic disorders, inflammatory, immune and oxidative stress. The methodology consisted of a three-step procedure…, This research was funded by the Spanich Ministerio de Economía y Competitividad (MINECO), grant number: AGL2013-49079-C2-1.2-R, SI

Oral cavity cancer is the most frequent malignancy of the head and neck. Unfortunately, despite educational interventions for prevention and early diagnosis, oral cancer patients are often diagnosed in advanced stages associated with poor prognosis and life expectancy. Therefore, there is an urgent need to find noninvasive biomarkers to improve early detection of this tumor. Liquid biopsy has emerged as a valuable tool in medical oncology which provides new horizons for improving clinical…, SI

En la provincia de Alicante (sureste español), la insuficiencia de recursos hídricos motivada por el incremento de las demandas desde los años sesenta y setenta del pasado s. XX para satisfacer usos urbanos y agrícolas e indigencia pluviométrica debido a la aridez natural, se ha convertido en uno de los principales problemas socio-territoriales y económicos. El incremento de recursos hídricos fue posible gracias a la sobreexplotación de acuíferos, la llegada de caudales externos, la…, In the province of Alicante (Southern Spain) the insufficiency of water resources has been motivated by the increase in demands since the 60s and 70s to satisfy urban and agricultural uses. Also, it is important to be added that the natural aridity of the territory has become one of the main economic and socio-territorial problems. The increase of resources became possible because the overexploitation of aquifers, the arrival of external flows, the reuse of treated water and in recent years, by…, Esta investigación es resultado del proyecto de investigación “Usos y gestión de recursos hídricos no convencionales en el litoral de las regiones de Valencia y Murcia como estrategia de adaptación a la sequía” (CSO2015-65182-C2-2-P) financiado por el Ministerio de Economía y Competitividad, SI

Medicinal plants are an ecosystem service directly implicated in human well-being. In many rural communities, they constitute a main treatment for disease or a source of disease prevention. Here, we review traditional knowledge of medicinal plants, the benefits they provide when cultivated in home gardens, and the determinants of knowledge about their uses in a rural parish in Amazonian Ecuador, where two ethnic groups prevail: indigenous Shuar and settled mestizos. Among 138 garden owners…, The authors thank the National Secretary of Higher Education, Science and Technology of Ecuador (SENESCYT) for the doctoral grant received by Veronica Caballero-Serrano. Josu G. Alday was supported by Ramón y Cajal fellowship, Spain [Grant number RYC-2016-20528]. Brian McLaren was supported by the Natural Sciences and Engineering Research Council, Canada [Discovery Grant number RPGIN/312/860-2012] and the Chimborazo Polytechnic University, Ecuador, SI

Revistas españolas que aparecen en el segundo cuartil de Google Scholar Metrics (GSM) no figuran en Journal Citation Reports (JCR). Hay serias diferencias entre Google Scholar Metrics y Thomson Reuter y una coincidencia plena: las dos son grandes multinacionales del sector de la información, aunque sus fuentes de ingresos siguen distintos caminos. Thomson Reuters cobra suculentas facturas para que se pueda acceder a sus bases de datos. España abonó en 2008…, The spanish journals that appear in the second quartile of Google Scholar Metrics (GSM) are not listed in the Journal Citation Reports (JCR). There are serious differences and one big coincidence between these two databases: they both belong to very large multinational information companies, Google and Thomson Reuters , whose sources of income are very different. While the access to Google Scholar Metrics is currently free, Thomson Reuters charges people…, SI

En el nuevo panorama mediático, caracterizado por la fragmentación y desafección de las audiencias hacia la televisión tradicional, urge la incorporación de innovadoras estrategias que atiendan a las demandas de sus públicos y conecten con ellos. El presente artículo analiza la capacidad de la Neurociencia para optimizar la producción de contenidos adaptados a las preferencias de los espectadores y comprueba la introducción de esta metodología en las radiotelevisiones públicas europeas. Para…, The new media landscape is characterized by the fragmentation and disaffection of the audience towards traditional television. Such a context requires innovative strategies to meet the needs of the public and connect with it. This article analyses the ability of Neuroscience to optimize the production of content adapted to audiences. For this purpose, a review of management and economic reports and corporate websites of the European public broadcasters (n=100) was carried out, as well as the…, Los resultados de este artículo son resultados del Proyecto de «Indicadores de gobernanza, financiación, rendición de cuentas, innovación, calidad y servicio público de las RTV europeas aplicables a España en el contexto digital» (CSO2015-66543-P), del Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia, del Ministerio de Economía y Competitividad de España, cofinanciado por el Fondo Europeo de Desarrollo Regional (FEDER) de la Unión Europea. Así como de la…, SI

We study the existence of homoclinic solutions for semilinear -Laplacian difference equations with periodic coefficients. The proof of the main result is based on Brezis-Nirenberg's Mountain Pass Theorem. Several examples and remarks are given, A. Cabada partially supported by Ministerio de Educacion y Ciencia, Spain, project MTM2007-61724, SI

Background: The systematic study of the human genome indicates that the inter-individual variability is greater than expected and it is not only related to sequence polymorphisms but also to gene copy number variants (CNVs). Congenital Adrenal Hyperplasia due to 21-hydroxylase deficiency (21OHD) is the most common autosomal recessive disorder with a carrier frequency of 1:25 to 1:10. The gene that encodes 21-hydroxylase enzyme, CYP21A2, is considered to be one of the most polymorphic human…, SI

Background Physical restraint is a procedure used frequently in long-term care. It is a controversial practice because its use is associated with numerous complications and also affects freedom and individual autonomy. The objective of this study was to examine the use of physical restraint of long-term care residents with the ability to move voluntarily. Methods We conducted a cross-sectional observational and correlational multi-center study. Nine centers agreed to participate. Of the 1,200…, Sociedad Canaria de Geriatría y Gerontología and the Fundación Canaria de Investigación Sanitaria financed this study., SI

Introduction Rheumatoid arthritis is an autoimmune disease in which joint inflammation leads to progressive cartilage and bone erosion. Matrix metalloproteinases (MMPs) implicated in homeostasis of the extracellular matrix play a central role in cartilage degradation. However, the role of specific MMPs in arthritis pathogenesis is largely unknown. The aim of the present study was to investigate the role of Mmp-8 (collagenase-2) in an arthritis model. Methods Arthritis was induced in Mmp8-…, The present work was supported by grants PI04/0783, PI08/0038, RETICS Program, RD08/0075 (RIER), all from Fondo de Investigación Sanitaria, Instituto de Salud Carlos III within the VI PN de I+D+I 2008-2011 with participation of FEDER funds (European Union). SG is supported by Xunta de Galicia, SI

Food addiction (FA) has been associated with greater psychopathology in individuals with eating disorders (ED) and obesity (OBE). The current study aims to provide a better phenotypic characterization of the FA construct by conducting a clustering analysis of FA in both conditions (ED and OBE). The total sample was comprised of 234 participants that scored positive on the Yale Food Addiction Scale 2.0. (YFAS-2) (119 bulimia nervosa (BN), 50 binge eating disorder (BED), 49 other specified…, We thank CERCA Programme/Generalitat de Catalunya for institutional support. This manuscript and research was supported by grants from the Ministerio de Economía y Competitividad (PSI2015-68701-R), by the Delegación del Gobierno para el Plan Nacional sobre Drogas (2017I067), by the Instituto de Salud Carlos III (ISCIII) (FIS PI14/00290 and PI17/01167), by the SLT006/17/00246 grant, funded by the Department of Health of the Generalitat de Catalunya by the call “Acció instrumental de programes de…, SI

En la presente tesis doctoral se examinó prospectivamente las asociaciones recíprocas entre la calidad de apego (madre, padre, compañeros) y los síntomas alimentarios y depresivos; se identificó mediante metaanálisis los principales mediadores que podrían explicar tales asociaciones y se comprobó un modelo mediacional integrador que demostró el efecto prospectivo del apego inseguro en el desarrollo de la sintomatología alimentaria a través de síntomas depresivos en la transición a la…

Abásolo Álvarez JA (1990) El conocimiento de las vías romanas. Un problema arqueológico. In: Simposio sobre la red viaria en la Hispania romana. Institución Fernando el Católico, Zaragoza, pp 7–20Google Scholar Alonso Trigueros JM (2014) Modelo gráfico para la datación de las vías romanas empedradas a partir del estudio de sus estados de frecuentación y del análisis superficial de roderas. Universidad Politécnica de Madrid, Madrid. Available at http://oa.upm.es/32697/. Accessed on 12 May…, GIS-based digital modelling tools, such as the well-known least cost paths (LCP), have been widely used in archaeology in recent years as ways of approaching forms of mobility in the past. Roman roads are among the best-known examples of ancient networks of paths and have been widely studied using such approaches. In this paper, we shall make a general re ection on the applicability of those tools for the modelling and analysis of ancient routes, with a special focus on Roman roads. Drawing…

Polyhydroxyalkanoates (PHA) are biodegradable polymers that can be intracellularly produced by microorganisms valorizing organic-rich wastes. In the present study, a PHA production system was fed with mussel cooker wastewater after acidogenic fermentation. Besides low pH (4.0 ± 0.3) and high salt (21.7 ± 2.9 g NaCl/L) concentrations, this wastewater also contained nitrogen concentrations (0.8 ± 0.1 g N/L), which were previously reported to be a challenge to the PHA accumulating bacteria…, This research was funded by the Spanish Government (AEI) through the FISHPOL (CTQ2014-55021-R) and TREASURE (CTQ2017-83225-C2-1-R) projects. The authors belong to the Galician Competitive Research Group GRC ED431C 2017/29 and to the CRETUS Strategic Partnership (ED431E 2018/01). All these programs are co-funded by the FEDER (EU), SI

Mine tailings containing trace metals arrived at the Doce River estuary, after the world’s largest mine tailings disaster (the Mariana disaster) dumped approximately 50 million m3 of Fe-rich tailings into the Doce River Basin. The metals in the tailings are of concern because they present a bioavailability risk in the estuary as well as chronic exposure hazards. Trace metal immobilization into sulfidic minerals, such as, pyrite, plays a key role in estuarine soils; however, this process is…, This work was funded by grants to AFB and TOF from Fundação de Amparo do Espirito Santo (FAPES/CNPq/CAPES Rio Doce 77683544/2017), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior CAPES—Finance Code 001 and CNPq (grant numbers, AFB: 301161/2017-8, TOF: 305996/2018-5; GNN: 409593/2018-4). The authors are grateful for the financial support provided by São Paulo Research Foundation (FAPESP, ADF grant number 2019/14800-5, HMQ grant number 2018/04259-2; MPK grant number 2020/06224-1; TOF…, SI

El artículo se centra en la realidad de los Centros Públicos Integrados en Galicia, aunque se presentan referencias a otras comunidades autónomas. Se define qué se entiende por centro público integrado, su origen, evolución y regulación normativa. Así mismo, se exponen los principales argumentos a favor de este tipo de centros y el debate suscitado entorno a su transformación o eliminación. Finalmente se recogen unas consideraciones de la autora, This paper focuses on the reality of Public Centers Integrated in Galicia, although we present references to other autonomous communities. We wanted to define what is meant by integrated public center, its origin, evolution and normative regulation. We have also presented the main arguments in favor of those centers and the debate about their transformation or elimination. Finally, the authoress presents her own considerations about the topic, SI

Background: The spread of the internet and Information and Communications Technologies (ICT) have completely changed society in the last few decades. The transfer of traditional face-to-face bullying to the virtual environment is one of the risks adolescents face in this new reality. The present study sought to explore the relationship between involvement in cyberbullying and behaviours such as internet and mobile usage and other risky online behaviours. Method: The sample consisted of 3,188…, Antecedentes: el uso generalizado de Internet y de las Tecnologías de la Información y las Comunicaciones (TIC) ha cambiado completamente la sociedad en las últimas décadas. La transferencia del tradicional acoso escolar al entorno virtual es uno de los riesgos a los que se enfrentan los adolescentes en esta nueva realidad. El presente estudio se planteó como objetivo explorar la relación entre ciberacoso y uso de Internet y teléfono móvil y otras conductas de riesgo en línea. Método: la…, This work was supported by the Delegación del Gobierno para el Plan Nacional sobre Drogas under Grant 2018/008. Rafael Pichel and Sandra Feijóo would like to acknowledge the funding by the Government of Galicia under grant “Programa de axudas á etapa predoutoral”. Mairéad Foody is funded by the Irish Research Council and the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 713279, SI

The 15th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis, In the past few decades, the synthesis of new heterocyclic compounds has been a subject of great interest due to their wide applicability. Among a large variety of heterocyclic compounds, heterocycles containing phthalazine moiety were reported to possess anticonvulsant, cardiotonic, and vasorelaxant activities. Therefore, a number of methods have been reported for the synthesis of phthalazine derivatives. Despite the available methods, the development of new synthetic methods for the efficient…

Major type of internal can coating used for food and beverages is made from epoxy resins, which contain among their components bisphenol A (BPA) or bisphenol A diglycidyl ether (BADGE). These components can be released and contaminate the food or beverage. There is no specific European legislation for coatings, but there is legislation on specific substances setting migration limits. Many investigations have paid attention to BPA due to its classification as endocrine disruptor, however, few…, The study was financially supported by the Ministerio de Ciencia, Innovación y Universidades, by Fondo Europeo de Desarrollo Regional (FEDER), and by Agencia Estatal de Investigación Ref. No. PGC2018-094518-B-I00 “MIGRACOATING” (MINECO/FEDER, UE), SI

La principal limitación en la producción de moluscos son las infecciones causadas por bacterias del género Vibrio, como V. neptunius, que provoca episodios de mortalidad y grandes pérdidas económicas. El conocimiento sobre la base molecular de la virulencia de V. neptunius es escaso. En este trabajo nos planteamos estudiar la producción de enzimas proteolíticas y la síntesis y utilización de sideróforos, para caracterizar la relación de estos factores en la ecología y virulencia de V. neptunius…

La ethosfera digital, como entorno cultural de interacciones digitales, propicia espacios de participación social y ciudadana donde se promueven valores y contravalores que determinan la construcción de la identidad personal de sus usuarios. La carencia de estudios para analizar los contravalores inmersos en las interacciones y espacios digitales ha propiciado el desarrollo de esta investigación, que busca analizar el alcance de la percepción de los estudiantes sobre la presencia de…, The digital ethosphere, as a cultural environment of digital interactions, provides spaces for social and citizen participation where certain values and counter-values are promoted that determine the users’ construction of their personal and cultural identity. The lack of studies that analyze the counter-values immersed in digital interactions and spaces has led to the development of this study, which seeks to analyze the students’ perception of the presence of counter-values on the Internet by…, Este trabajo se enmarca en los siguientes proyectos: ‘Alfamed’ (Red Euroamericana de Investigadores), con el apoyo del Proyecto I+D «YOUTUBERS E INSTAGRAMMERS: LA COMPETENCIA MEDIATICA EN LOS PROSUMIDORES EMERGENTES» (RTI2018-093303-B-I00), financiado por la Agencia Estatal de Investigación del Ministerio de Ciencia, Innovación y Universidades de España y el Fondo Europeo de Desarrollo Regional (FEDER); «CONNECT-ID. La identidad hiperconectada de la juventud y su percepción del tiempo en el…, SI

The development of biotechnological processes through which high added value products can be obtained, using non-valuable industrial streams, has become a primary objective in the scope of sustainability and circular economy strategies. It is in this context where this research report is framed, in which a biorefinery approach has been developed using mussel processing wastes (MPW) as a resource, thus avoiding the environmental impacts involved in their management. Through an enzymatic pre-…, This research has been financially supported by the European project iFermenter, Spain (Grant Agreement 79057). IFermenter is a project funded under the “Bio-Based Industries Joint Undertaking under the European Union’s Horizon 2020 research and innovation programme”. The authors belong to the Galician Competitive Research Group (GRC ED431C 2017/29) and to the Cross-disciplinary Research in Environmental Technologies (CRETUS Research Center, ED431E 2018/01), SI

The low limits of detection and information regarding the concentration and size distribution of nanoparticles provided by single particle inductively coupled plasma mass spectrometry (spICP-MS) has been taken in advance for assessing released silver nanoparticles from (nano)textiles (nanosilver textiles). The releasing procedure consisted of using orbital-horizontal shaking (100 rpm, 20 °C, 30 min) and ultrapure water (10 mL) as an extractant, and it was found to guarantee silver nanoparticles…, The authors wish to acknowledge the financial support of the Ministerio de Economía y Competitividad (projects INNOVANANO, reference RT2018–099222-B-100), and the Xunta de Galicia (Grupo de Referencia Competitiva, grant number ED431C2018/19). I. Rujido-Santos thanks the Xunta de Galicia and the European Social Fund (FSE) for a pre-doctoral grant (ref. ED481A-2018/127), SI

An efficient Lewis acid-assisted asymmetric carbonyl-ene reaction to set the 1α-hydroxyl functionality of enol-triflate, precursor of the A-ring of the hormone calcitriol and its 1α-hydroxyderivatives, is described. The secondary parallel hypercalcemic effects associated with the treatment of several hyperproliferative diseases with the natural hormone 1α,25-dihydroxyvitamin D3 (calcitriol) and/or known active vitamin D metabolites and analogs, demand the development of efficient and rapid…, This research was funded by ENDOTHERM GmbH, Xunta de Galicia (GRC/ED431B/20) and the University of Santiago de Compostela (Spain), SI

Background: differences in cell-free DNA (cfDNA) fragments have been described as a valuable tool to distinguish cancer patients from healthy individuals. We aim to investigate the concentration and integrity of cfDNA fragments in saliva from oral squamous cell carcinoma (OSCC) patients and healthy individuals in order to explore their value as diagnostic biomarkers. Methods: saliva samples were collected from a total of 34 subjects (19 OSCC patients and 15 healthy controls). The total…, SI

Deviant siblings have been considered as role models for future delinquent behavior; however, previous studies have led to inconsistent results in this regard. The goal of the current meta-analysis was to analyze the effect of deviant non-twin siblings on future delinquency. The potential moderation effects of birth order, sex dyad, age of siblings, publication year, study length, and sample size were analyzed. Six databases were searched for studies: PsycInfo, MEDLINE, Criminal Justice…, SI

Los resultados de esta tesis doctoral se suman a una línea específica de investigación sobre el audiovisual público en Europa. Primero, porque ofrecen un marco teórico sobre el concepto de valor y servicio público, para entender y construir argumentos que justifiquen la existencia de estos servicios en el tablero digital. De esta forma, y al lidiar con un tema esencial para el futuro de las organizaciones de medios de servicio público y del sector audiovisual en Europa, esta tesis doctoral…

Este estudio analiza una serie de variables demográficas, preoperatorias, quirúrgicas y anatomopatológicas en pacientes diagnosticados de cáncer de recto intervenidos con intención curativa, con el objetivo principal de conocer su influencia en la recurrencia locorregional y a distancia y en la supervivencia global y libre de enfermedad. Como segundo objetivo hemos planteado valorar la capacidad pronóstica de la estadificación ganglionar del sistema TNM comparandola con otros sistemas como el…

Efficient identification of cognitive decline and Alzheimer’s disease (AD) risk in early stages of the AD disease continuum is a critical unmet need. Subjective cognitive decline is increasingly recognized as an early symptomatic stage of AD. Dyadic cognitive report, including subjective cognitive complaints (SCC) from a participant and an informant/study partner who knows the participant well, represents an accurate, reliable, and efficient source of data for assessing risk. However, the…, SI

In recent years, novel food is becoming an emerging trend increasingly more demanding in developed countries. Food proteins from vegetables (pulses, legumes, cereals), fungi, bacteria and insects are being researched to introduce them in meat alternatives, beverages, baked products and others. One of the most complex challenges for introducing novel foods on the market is to ensure food safety. New alimentary scenarios drive the detection of novel allergens that need to be identified and…, SI

In this paper, we first use the information we have on the patients of an oncology day hospital to distribute the treatment schedules they have in each of the visits to this centre. To do this, we propose a deterministic mathematical programming model in such a way that we minimise the duration of the waiting room stays of the total set of patients and taking into account the restrictions of the circuit. Secondly, we will look for a solution to the same problem under a stochastic approach. This…, This research has been funded by the ERDF, the Government of Spain/AEI [grant MTM2017- 87197-C3-3-P] and the Xunta de Galicia [Grupos de Referencia Competitiva ED431C2017/38, and ED431C 2021/24]., SI

Background: HTLV-1 infection is a neglected disease, despite estimates of 10 million people infected worldwide and producing life-threatening illnesses in 10% of carriers. Sexual transmission is the main route of contagion. However, HTLV-1 is not listed among sexually transmitted infections (STIs). Methods: Serum from all consecutive individuals who had attended six STI clinics across Spain during the last 12 months were tested for HTLV antibodies using a commercial enzyme immunoassay (EIA).…, The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was funded in part by grant UNIR-itei 005/23, Fondos Feder-Instituto de Salud Carlos III (FIS-PI-21/1717) and Fundación Mutua Madrileña (AP-174112020), 2023, SI

The aim of this work is to provide a non-destructive testing technique to obtain the physical properties of a given material, based on a series of images, obtained through a non-invasive procedure, that capture the experimental propagation of a Rayleigh waves packet travelling through it, and allowing us to obtain the phase velocity of the waves packet. The proposed procedure involves a minimization technique that requires the numerical simulation of the travelling waves to obtain the optimal…, The authors would like to acknowledge the cooperation of the members of the Optical Metrology research Group of the Applied Physics Department of the University of Vigo who provided the experimental data for this work as long as their input and experience on the matter., SI

The impact of an outbreak of bovine viral diarrhea (BVD) on reproductive performance and milk production was investigated in 28 Spanish dairy herds using an observational study design. Mean calving to conception interval (CCI), mean number of inseminations per conception (AI/P) and mean daily milk yield were recorded from herds affected by outbreaks. Infection was confirmed by evidence of viral transmission to young stock (heifers 9–24 months) and persistently infected animals, after previous…, The authors thank the Subdirección Xeral de Gandería and the Laboratorio de 173 Sanidade e Produción Animal (Consellería do Medio Rural, Xunta de Galicia)., SI

We describe the synthesis of trihydroxylated cyclohexane β-amino acids from (−)-shikimic acid, in their cis and trans configuration, and the incorporation of the trans isomer into a trans-2-aminocyclohexanecarboxylic acid peptide chain. Subsequently, the hydroxyl groups were partially or totally deprotected. The structural study of the new peptides by FTIR, CD, solution NMR and DFT calculations revealed that they all fold into a 14-helix secondary structure, similarly to the homooligomer of…, This work has received financial support from the Xunta de Galicia and the European Regional Development Fund- ERDF (ED431C 2018/30, ED431F 2020/05 and Centro singular de investigación de Galicia accreditation 2019-2022, ED431G 2019/ 03). Funding from the Agencia Estatal de Investigación (AEI) and the European Regional Development Fund- ERDF (RTI2018098795-A-I00 and PDC2022-133402-I00) is also acknowledged. R. G.-F. thanks Ministerio de Ciencia, Innovación y Universidades for a “Ramón y Cajal”…, SI

Many invasive alien species (IAS) produce secondary metabolites that affect how other plants function (allelopathic compounds) and can drive other species invasion, as proposed by the invasional meltdown hypothesis. Acacia melanoxylon and Eucalyptus globulus are two of such species. In this study, we analyzed the germination response of seven IAS (Acacia dealbata, Acacia mearnsii, Acacia melanoxylon, Acacia longifolia, Eucalyptus globulus, Paraserianthes lophantha, Phytolacca americana) and a…, SI

Pérez Rivas, Natalia / Ordoñez Mayán, Lucía / Guinarte Cabada, Gumersindo / Muñoz Barús, José Ignacio / Vázquez-Portomeñe Seijas, Fernando / Rodríguez Calvo, María Sol (2013): “Violence against women in Spain: results of a medico-legal and criminological study”, 13th Annual Conference of the European Society of Criminology, Budapest, 4-7 september 2013 [Poster], The purpose of this work was to analyse the characteristics of gender violence from the medico-legal and criminal perspectives. The focus of our attention is on the followings aspects: to analyze the sociodemographic characteristics of victims and aggressors and the prevalence of different diseases associated with the abuse; to determine the prevalence of gender violence in its different varieties; to check the compliance with the protocols relating to the development of medico-legal documents…, This proyect was supported by Grants from Ministerio de Ciencia e Innovación (FEM 2010-22350-C02-01 and FEM 2010-22350-C02-02)

Polyelectrolyte complexes (PECs) are polymeric structures formed by the self-assembly of oppositely charged polymers. Novel biomaterials based on PECs are currently under investigation as drug delivery systems, among other applications. This strategy leverages the ability of PECs to entrap drugs under mild conditions and control their release. In this study, we combined a novel and sustainably produced hemicellulose-rich lignosulphonate polymer (EH, negatively charged) with polyethyleneimine (…, The authors would like to thank Dr. P. Oinonen and Ecohelix AB for providing samples of the Ecohelix polymer and scientific advice on its use. The research leading to these results was financially supported by Nordforsk, within the Nordic Green Growth Research and Innovation Program (project name: “High-Value Products from Lignin”). A.A. acknowledges funding from ‘la Caixa’ Foundation (ID 100010434) with a fellowship code LCF/BQ/ PR22/11920003. Open Access funding provided thanks to the CRUE-…, SI

We examine the licensing decision of a non-producer innovator with a new technology that enables the manufacture of a saleable product. The technology is licensed and each user privately knows its innovation-related production cost, whereas the licensor only knows, with a certain probability, that this cost may be low (the user is efficient) or high (the user is inefficient). When a single licence is granted through separating contracts, only the contract intended for the inefficient user…, Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. The authors acknowledge financial aid from Consellería de Cultura, Educación, Formación Profesional e Universidades (Xunta de Galicia) through Grant Consolidación e estruturación – 2023 GRC GI-2016 Análise económica dos mercados e institucións (AEMI). The second author also thanks financial support from the Spanish Ministry of Science and Innovation research project PID2020-118119 GB-I00. They declare that…, SI

En este trabajo se examina la adecuación de las respuestas de los estudiantes preuniversitarios gallegos a la norma ortográfica dictada por la Real Academia Española en Ortografía de la lengua española (2010). Para ello, se ha elaborado un corpus léxico que tiene como fuentes la aplicación informática de DISPOGAL y un listado de lemas de cada centro de interés con sus variantes. El objetivo del estudio reside en determinar qué tipo de errores cometen los informantes y cuáles de ellos son más o…

Antecedentes: La identificación de los factores asociados al consumo de medicamentos resulta clave para el diseño de campañas de uso racional del medicamento. Las Encuestas Nacionales de Salud constituyen herramientas de gran utilidad para este fin. Objetivo: Estudiar la evolución del consumo de medicamentos en población general adulta en el período 1987-2006 y sus factores asociados. Método: Estudio de corte transversal. Población reclutada por las distintas ENS. Como variables dependientes se…

El presente trabajo tiene por objeto el análisis estadístico de diversos datos relativos a la delincuencia juvenil en nuestra Comunidad Autónoma gallega, datos que corresponden a los años 2004, 2005 y 2006 y que, sin lugar a dudas, pueden contribuir al mejor entendimiento de este sector de la criminalidad. Para ello, los referidos datos estadísticos, en cada uno de los años indicados, se examinan de forma aislada, para, finalmente, concluir con un estudio comparativo entre dichas fechas con el…

O EEES ao facer fincapé nos procesos de aprendizaxe do alumnado esixe modificacións na docencia que debe entenderse sobre todo como unha axuda e mediadora dos procesos de aprendizaxe do alumnado. Preséntanse algunhas ideas xerais sobre os procesos de ensino-aprendizaxe, algúns criterios para a selección de actividades e algunhas estratexias didácticas que favorecen a implicación do alumnado nese proceso de aprendizaxe, tales como a aprendizaxe baseada en problemas, a través de proxectos, o…

La catedral de Sevilla es un monumento de gran fuerza histórica, vivo espiritual y patrimonialmente. La génesis y dinámica de la organización actual responde a un esfuerzo colectivo, prolongado en el tiempo durante más de veinte años; esta investigación señala sus etapas y sus claves patrimoniales. La catedral coordina y compagina la naturaleza primigenia del templo con la restauración y conservación, incentiva la investigación en sus archivos y bibliotecas, promueve y acoge actividades. La…