Resultados totales (Incluyendo duplicados): 44423
Encontrada(s) 4443 página(s)
Encontrada(s) 4443 página(s)
CORA.Repositori de Dades de Recerca
doi:10.34810/data92
Dataset. 2021
SUPPLEMENTAL DATA OF: EFFECTIVENESS OF CONSUMERS WASHING WITH SANITIZERS TO REDUCE HUMAN NOROVIRUS ON MIXED SALAD
- Anfruns-Estrada, Eduard
- Bottaro, Marilisa
- Pintó Solé, Rosa María
- Guix Arnau, Susana
- Bosch, Albert
Viral titers were collected following a method based on the ISO 15216-1 (2017) protocol with some modifications, on experimentally inoculated ready-to-eat vegetables. See Materials and Methods section of the manuscript. Effect of the sanitizer wash on virus reduction was determined by calculating the log units (Nt/N0), where N0 is the titer of virus recovered on unwashed control samples and Nt is the titer of virus recovered on washed sample.
Proyecto: //
CORA.Repositori de Dades de Recerca
doi:10.34810/data933
Dataset. 2023
OPENFOAM FILES AND PROCESSED DATA OF THERMALLY-DRIVEN WINDS ON MARS: A REVIEW AND A SLOPE EFFECT NUMERICAL STUDY
- Villardi de Montlaur, Adeline de
- Arias Calderón, Santiago
The dataset contains OpenFOAM files and processed data corresponding to the paper: Montlaur, A., Arias, S., & Rojas, J. I. (2024). Thermally driven winds on Mars: A review and a slope effect numerical study. Journal of Geophysical Research: Planets, 129, e2023JE007987. https://doi.org/10.1029/2023JE007987.
The dataset is structured into the following 6 folders: 1) ReferenceCase: include the reference/main case, 2) NoRadiationTest: include the case without radiation, 3) HeightTest: include the cases used for domain height validation (7.5 and 5 km), 4) MeshTest: include the 2 cases used for mesh validation (389 and 607 elements), 5) TimeStepTest: include the 2 cases used for mesh validation (0.12s and 0.18 s), 6) SlopeEffect: include 5 cases of slope study (5, 10, 15, 25, 30º). Each study case includes the necessary "0," "system," and "constant" folders to run simulations in OpenFOAM. Text files with post-processing data (computed at midslope, "slope50") are also included for each case.
Proyecto: //
CORA.Repositori de Dades de Recerca
doi:10.34810/data936
Dataset. 2023
REPLICATION DATA FOR: CHIR99021 CAUSES INACTIVATION OF TYROSINE HYDROXYLASE AND DEPLETION OF DOPAMINE IN RAT BRAIN STRIATUM
- Hamdon, Sally
- Fernandez-Gonzalez, Pol
- Omar, Muhammad Yusof
- González Sepúlveda, Marta
- Ortiz, Jordi
- Gil, Carles
CHIR99021, also known as laduviglusib or CT99021, is a Glycogen-synthase kinase 3β (GSK3β) inhibitor, which has been reported as a promising drug for cardiomyocyte regeneration or treatment of sensorial hearing loss. Since the activation of dopamine (DA) receptors regulates dopamine synthesis and they can signal through the β-arrestin pathway and GSK3β, we decided to check the effect of GSK3β inhibitors (CHIR99021, SB216763 and lithium ion) on the control of DA synthesis. Using ex vivo experiments with minces from rat brain striatum, we observed that CHIR99021, but not SB216763 or lithium, causes complete abrogation of both DA synthesis and accumulation, pointing to off-target effects of CHIR99021. This decrease can be attributed to tyrosine hydroxylase (TH) inhibition since the accumulation of L-DOPA in the presence of a DOPA decarboxylase inhibitor was similarly decreased. On the other hand, CHIR99021 caused a dramatic increase in the DOPAC / DA ratio, an indicator of DA metabolization, and hindered DA incorporation into striatum tissue. Tetrabenazine, an inhibitor of DA vesicular transport, also caused DA depletion and DOPAC / DA ratio increase to the same extent as CHIR99021. In addition, both CHIR99021 or SB216763, but not lithium, decreased TH phosphorylation in Ser19, but not in Ser31 or Ser40. These results demonstrate that CHIR99021 can lead to TH inactivation and DA depletion in brain striatum, opening the possibility of its use in DA-related disorders, and shows effects to be considered in future clinical trials.
Proyecto: //
CORA.Repositori de Dades de Recerca
doi:10.34810/data93
Dataset. 2022
ANTIBODY RESPONSES TO THE RTS,S/AS01E VACCINE AND PLASMODIUM FALCIPARUM ANTIGENS AFTER A BOOSTER DOSE WITHIN THE PHASE 3 TRIAL IN MOZAMBIQUE
- Augusto J. Nhabomba
- Carlota Dobaño
- Chenjerai Jairoce
- David Cavanagh
- Deepak Gaur
- Evelina Angov
- Gemma Moncunill
- Inocencia Cuamba
- Itziar Ubillos
- James G. Beeson
- Joseph J. Campo
- Lina Sánchez
- Marta Vidal
- Nana Aba Williams
- Núria Diez-Padrisa
- Pedro Carlos Paulino Aide
- Ross L. Coppel
- Ruth Aguilar
- Sheetij Dutta
The RTS,S/AS01E vaccine has shown consistent but partial vaccine efficacy in a pediatric phase 3 26 clinical trial using a 3-dose immunization schedule. A fourth dose 18 months after the primary 27 vaccination was shown to restore the waning efficacy. However, only total IgG against the 28 immunodominant malaria vaccine epitope has been analyzed following the booster. To better 29 characterize the magnitude, nature and longevity of the immune response to the booster, we 30 measured levels of total IgM, IgG and IgG1-4 subclasses against three constructs of the 31 circumsporozoite protein (CSP) and the hepatitis B surface antigen (HBsAg, also present in RTS,S) 32 by quantitative suspension array technology in 50 subjects in the phase 3 trial in Manhiça, 33 Mozambique. To explore the impact of vaccination on naturally acquired immune responses, we 34 measured antibodies to P. falciparum antigens not included in RTS,S. We found increased IgG, 35 IgG1, IgG3 and IgG4, but not IgG2 nor IgM, levels against vaccine antigens one month after the 4th 36 dose. Overall, antibody responses to the booster dose were lower than the initial peak 37 response to primary immunization and children had higher IgG and IgG1 levels than infants. 38 Higher anti-Rh5 IgG and IgG1-4 levels were detected after the booster dose, suggesting that RTS,S 39 partial protection could increase some blood stage antibody responses. Our work shows that the 40 response to the RTS,S/AS01E booster dose is different from the primary vaccine immune 41 response and highlights the dynamic changes in subclass antibody patterns upon the vaccine 42 booster and with acquisition of adaptive immunity to malaria.
Proyecto: //
CORA.Repositori de Dades de Recerca
doi:10.34810/data94
Dataset. 2021
SUPPLEMENTAL DATA OF: LONG-TERM FARMING SYSTEMS AND LAST CROP SOWN SHAPE THE SPECIES AND FUNCTIONAL COMPOSITION OF THE ARABLE WEED SEEDBANK
- Rotchés Ribalta, Roser
- Sans, Xavier (Sans i Serra)
- Mäder, Paul
Species diversity descriptors (abundance, species richnnes, Shannon’s diversity index and Pielou’s evenness index) and functional diversity descriptors (functional richness, functional evenness, functional dispersion, Rao Quadratic enthropy and functional redundancy) for each sample inventoried from the DOK long-term experimental field trial used by Rotchés-Ribalta et al. (Applied Vegetation Science)
Proyecto: //
CORA.Repositori de Dades de Recerca
doi:10.34810/data956
Dataset. 2023
REPLICATION DATA FOR PLANT COMMUNITY CLIMATIC DISTANCE IN A FIELD CLIMATE CHANG EXPERIMENT
- Pérez Navarro, María Ángeles
- Lloret Maya, Francisco
- Ogaya Inurrigarro, Romà
- Estiarte, Marc
- Peñuelas, Josep
Location in the climatic niche over several years of plant comunities from a field manipulation experiment of climate change carried on in Garraf (Spain).
1. Description of methods used for collection-generation of data:
Field data: vegetation surveys based on transects within experimental plots
Species distribution data: species occurrences along their geographical distributions were obtained from the database of the Global Biodiversity Information Facility GBIF 2019,)
Climate data: climatic variables were obtained for the period 1979-2013 at 1-km2 resolution from CHELSA v.1.2 database Karger et al. (2018) DOI: 10.1038/sdata.2017.122; Karger et al., (2017) DOI: 10.16904/envidat.228.v2.1
See details in DOI: 10.1111/1365-2745.14233
2. Methods for processing the data:
A principal component analysis (PCA) was applied to reduce the dimensionality of the 13 climatic variables to the first two PCA axes. The species occurrences from the geographic space were translated into the two-dimensional climatic space defined by the two PCA axes. A two-dimensional kernel density function was applied to the species occurrences in the climatic space. The centroid of each species niche was obtained as the center of gravity of the niche. The observed climate at the study site for the average of the experimental period 1999-2014 and for each year were translated into the two-dimensional climatic space. The Euclidean distance in the climatic space between community location (based on species centroid averaged weighed by species's abundance) and the location of the observed climate in the respective years was calculated.
Proyecto: //
CORA.Repositori de Dades de Recerca
doi:10.34810/data957
Dataset. 2023
DATA OF THE ARTICLE "EXAMINING THE ADSORPTION OF GASES INTO SOLID CRYSTALLINE MOLECULAR COPPER(II) 3,5-BIS(TRIFLUOROMETHYL)BENZOATE DERIVATIVES"
- Vallcorba Valls, Oriol
- Fraile-Sainz, Julio C.
- Domingo, Concepcion
- Ayllon, Jose Antonio
The data set contains the experimental results of the figures shown in the article, including the figures in the supplementary materials. They were used to characterize the texture of the samples (adsoption/desoption of gases), it crystalline nature and modification due to temperature and/or gas pressure variations, and their thermal estability.
Proyecto: //
CORA.Repositori de Dades de Recerca
doi:10.34810/data958
Dataset. 2024
REPLICATION DATA FOR: "CONSISTENCY IN CLIMATE CHANGE IMPACT REPORTS AMONG INDIGENOUS PEOPLES AND LOCAL COMMUNITIES DEPENDS ON SITE CONTEXTS"
- Schunko, Christoph
- Reyes Garcia, Victoria
Indigenous Peoples and local communities are heavily affected by climate change impacts in the atmospheric system and on biophysical elements that support their livelihood activities. Investigating local understandings of these changes, and their patterned distribution, is essential to effectively support monitoring and adaptation strategies. In this study, we aimed to understand the consistency in climate change impact reports among Indigenous Peoples and local communities and factors influencing consistency at site and individual levels. We conducted cross-cultural research among iTaukei (Fiji), Dagomba (Ghana), Fisher (Tanzania), Tsimane’ (Bolivia), Bassari (Senegal), Ribeirinhos (Brazil), Mapuche (Chile), Mongolian (China), Tibetan (China) and Daasanach (Kenya) communities using semi-structured interviews, focus groups and surveys among 1,860 individuals. We found that more than two-thirds of individual reports of climate change impacts match site-confirmed reports. Consistency in reports is higher for changes related to pastoralism than crop production and wild plant gathering and higher for changes related to temperature, seasons and precipitation than air masses. Individual nature experience, Indigenous and local knowledge and local family roots are not significantly associated with consistency in reports across sites, but site-specific associations are prevalent. These results indicate that despite high average consistency among sites, there is considerable variation caused by site-specific factors, including livelihood activities pursued, socio-cultural settings and environmental conditions. Site contexts and related consistency in climate change impact reports need to be taken into account for climate change monitoring and adaptation planning.
Proyecto: //
CORA.Repositori de Dades de Recerca
doi:10.34810/data95
Dataset. 2021
TOTAL ION CHROMATOGRAMS OBTAINED BY SPME-GC-MS OF VOLATILE FINGERPRINT OF OLIVE OIL SAMPLES (N=174)
- Quintanilla-Casas, Beatriz
- Bustamante Alonso, Julen
- Guardiola Ibarz, Francesc
- García-González, Diego Luis
- Barbier, Sara
- Bendini, Alessandra
- Gallina Toschi, Tullia
- Vichi, S. (Stefania)
- Tres Oliver, Alba
Dataset containing SPME-GC-MS raw analytical data (total ion chromatograms, not aligned) obtained and used by Quintanilla-Casas et al. (LWT - Food Science and Technology 121: 108936). Data correspond to the volatile fingerprint of 174 authentic and traceable virgin olive oil samples previously graded by six official sensory panels (data from 2 outlier samples are not included) in the framework of OLEUM project (EC H2020 Programme 2014–2020). Briefly, data correspond to SPME-GC-MS scan intensities of the total ion chromatogram at each retention time from 5.5 to 61.96 min. These data were aligned and used under a fingerprinting approach by Quintanilla-Casas et al. to develop a classification model (PLS-DA approach) to verify the sensory quality of virgin olive oils, and it was suggested as an instrumental method to support sensory panels.
Proyecto: //
CORA.Repositori de Dades de Recerca
doi:10.34810/data96
Dataset. 2021
SUPPLEMENTAL DATA OF: STABLE OXYGEN ISOTOPES REVEAL HABITAT USE BY MARINE MAMMALS IN THE RÍO DE LA PLATA ESTUARY AND ADJOINING ATLANTIC OCEAN
- Drago, Massimiliano
- Valdivia, Meica
- Bragg, Daniel
- González, Enrique M.
- Aguilar, Àlex
- Cardona Pascual, Luis
The bone stable oxygen isotope values and the distance of the stranding site from the innermost point of the estuary for thirteen marine mammal species (Otaria flavescens, Arctocephalus australis, Pontoporia blainvillei, Ziphius cavirostris, Phocoena dioptrica, Phocoena spinipinnis, Delphinus delphis, Globicephala melas, Grampus griseus, Lagenodelphis hosei, Orcinus orca, Pseudorca crassidens and Tursiops truncatus) from the Río de la Plata estuary and the adjoining western South Atlantic Ocean. Stable oxygen isotope values (δ18O) are reported relative to the Vienna Standard Mean Oceanic Water (V-SMOW).
Proyecto: //
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