BUSCADOR RECOLECTA

Viral titers were collected following a method based on the ISO 15216-1 (2017) protocol with some modifications, on experimentally inoculated ready-to-eat vegetables. See Materials and Methods section of the manuscript. Effect of the sanitizer wash on virus reduction was determined by calculating the log units (Nt/N0), where N0 is the titer of virus recovered on unwashed control samples and Nt is the titer of virus recovered on washed sample.

The aim of this work was to evaluate a new variety of hooded barley (var. Mochona) in small ruminants (Manchega and Lacaune sheep) and to compare with a commercial triticale (var. Titania). The cultivars were harvested and processed as fodder hay and as silage during two consecutive years. The fodder hay results are present in the first 6 sheets of the excel whereas the silage results are in the next 7 sheets. The results are organized by chemical composition, dry matter intake and nutritional value. Resumen: El objetivo de este trabajo fue evaluar una nueva variedad de cebada encapuchada (var. Mochona) en pequeños rumiantes (oveja Manchega y Lacaune) y compararla con un triticale comercial (var. Titania). Los cultivares fueron cosechados y procesados como heno forrajero y ensilado durante dos años consecutivos. Los resultados del heno forrajero están presentes en las primeras 6 hojas del Excel, mientras que los resultados del ensilado están en las siguientes 7 hojas. Los resultados están organizados por composición química, ingestión de materia seca y valor nutricional.

This dataset contains the raw data generated by the technological study and registration of the photogrammetry and 3D modelling of the refit set nº 41 of the 497D level of the Cova Gran de Santa Linya (south-eastern Pyrenees, Iberian Peninsula). The refit set is composed of 9 pieces that make up 4 morphometrically distinct artefacts. The physical characteristics of the pieces are tabulated in the database, the relationship between the pieces can be consulted in the flowchart. The Materials to reproduce the process folder contains the files that make it possible to reproduce the process described in the protocol. An example of the files obtained in photogrammetry is included (example piece). The other subfolders contain the 3D data files (.obj, .mtl; .jpg) that allow the virtual models and the animation sequence to be reconstructed. In addition, two videos show the synthesis of the process with the main steps of the process.

The dataset contains simulated measurements of the polarization state (Stoke parameters) of the received photons in the case that the quantum channel is affected by both environmental events and eavesdropping. This dataset is partially supported by the European Commission through the HORIZON ALLEGRO project (G.A. 101092766), from the AEI IBON (PID2020-114135RB-I00) project and from the ICREA Institution.

The dataset gathers information of concerts and record-listening sessions of 20th-century art music in Barcelona (Spain) between 1948 and 1960. The research was focused on the music programmed by several small venues and select circles of Barcelona during Franco’s regime: Bartomeu House, Club 49, Institut français de Barcelone and Joventuts Musicals de Barcelona. As a selection criterion, all pieces written from 1900 onwards have been included. The first file contains 940 references of musical pieces played in live concerts and the second file contains 386 references of musical pieces included in record-listening sessions.

This dataset corresponds to the results published in: Viejo-Sobera, R., Redolar-Ripoll, D., Boixadós, M., Palaus, M., Valero-Cabré, A., & Marron, E. M. (2017). Impact of prefrontal theta burst stimulation on clinical neuropsychological tasks. Frontiers in neuroscience, 11, 462. https://doi.org/10.3389/fnins.2017.00462 The data was collected in 2014-2015 at the Cognitive NeuroLab (cognitiveneurolab.org, Universitat Oberta de Catalunya, UOC) as part of a project founded by the Spanish Ministerio de Economía y Competitividad (grant number: PSI2012-36610; PI Diego Redolar Ripoll).

Dataset on the results of PDC, LDH and AHD enzymatic characterization, ADH, LDH and PDC reactions towards pH, lactic acid synthesis using 100% CO2 and synthetic gas mixture mimicking real off-gasses of blast furnace of iron&steel industry.

The dataset contains OpenFOAM files and processed data corresponding to the paper: Montlaur, A., Arias, S., & Rojas, J. I. (2024). Thermally driven winds on Mars: A review and a slope effect numerical study. Journal of Geophysical Research: Planets, 129, e2023JE007987. https://doi.org/10.1029/2023JE007987. The dataset is structured into the following 6 folders: 1) ReferenceCase: include the reference/main case, 2) NoRadiationTest: include the case without radiation, 3) HeightTest: include the cases used for domain height validation (7.5 and 5 km), 4) MeshTest: include the 2 cases used for mesh validation (389 and 607 elements), 5) TimeStepTest: include the 2 cases used for mesh validation (0.12s and 0.18 s), 6) SlopeEffect: include 5 cases of slope study (5, 10, 15, 25, 30º). Each study case includes the necessary "0," "system," and "constant" folders to run simulations in OpenFOAM. Text files with post-processing data (computed at midslope, "slope50") are also included for each case.

CHIR99021, also known as laduviglusib or CT99021, is a Glycogen-synthase kinase 3β (GSK3β) inhibitor, which has been reported as a promising drug for cardiomyocyte regeneration or treatment of sensorial hearing loss. Since the activation of dopamine (DA) receptors regulates dopamine synthesis and they can signal through the β-arrestin pathway and GSK3β, we decided to check the effect of GSK3β inhibitors (CHIR99021, SB216763 and lithium ion) on the control of DA synthesis. Using ex vivo experiments with minces from rat brain striatum, we observed that CHIR99021, but not SB216763 or lithium, causes complete abrogation of both DA synthesis and accumulation, pointing to off-target effects of CHIR99021. This decrease can be attributed to tyrosine hydroxylase (TH) inhibition since the accumulation of L-DOPA in the presence of a DOPA decarboxylase inhibitor was similarly decreased. On the other hand, CHIR99021 caused a dramatic increase in the DOPAC / DA ratio, an indicator of DA metabolization, and hindered DA incorporation into striatum tissue. Tetrabenazine, an inhibitor of DA vesicular transport, also caused DA depletion and DOPAC / DA ratio increase to the same extent as CHIR99021. In addition, both CHIR99021 or SB216763, but not lithium, decreased TH phosphorylation in Ser19, but not in Ser31 or Ser40. These results demonstrate that CHIR99021 can lead to TH inactivation and DA depletion in brain striatum, opening the possibility of its use in DA-related disorders, and shows effects to be considered in future clinical trials.

The RTS,S/AS01E vaccine has shown consistent but partial vaccine efficacy in a pediatric phase 3 26 clinical trial using a 3-dose immunization schedule. A fourth dose 18 months after the primary 27 vaccination was shown to restore the waning efficacy. However, only total IgG against the 28 immunodominant malaria vaccine epitope has been analyzed following the booster. To better 29 characterize the magnitude, nature and longevity of the immune response to the booster, we 30 measured levels of total IgM, IgG and IgG1-4 subclasses against three constructs of the 31 circumsporozoite protein (CSP) and the hepatitis B surface antigen (HBsAg, also present in RTS,S) 32 by quantitative suspension array technology in 50 subjects in the phase 3 trial in Manhiça, 33 Mozambique. To explore the impact of vaccination on naturally acquired immune responses, we 34 measured antibodies to P. falciparum antigens not included in RTS,S. We found increased IgG, 35 IgG1, IgG3 and IgG4, but not IgG2 nor IgM, levels against vaccine antigens one month after the 4th 36 dose. Overall, antibody responses to the booster dose were lower than the initial peak 37 response to primary immunization and children had higher IgG and IgG1 levels than infants. 38 Higher anti-Rh5 IgG and IgG1-4 levels were detected after the booster dose, suggesting that RTS,S 39 partial protection could increase some blood stage antibody responses. Our work shows that the 40 response to the RTS,S/AS01E booster dose is different from the primary vaccine immune 41 response and highlights the dynamic changes in subclass antibody patterns upon the vaccine 42 booster and with acquisition of adaptive immunity to malaria.