BUSCADOR RECOLECTA

13 pages. -- S1. Device characterization and Experimental data. -- Table S2. RPERI modules with varying number of fingers, and hence a varying perimeter, but a fixed total area. -- Figure S1. Leakage current measured as a function of the temperature on TiN/10nm Ge60Se40/TiN (D16). -- Figure S2. TiN/10nm Ge60Se40/TiN (D16) C-V-f and G-V-f vs Temperature (T). -- Figure S3. Leakage current measured as a function of the temperature on TiN/20nm Ge50Se50/TiN (D21) in the (left) +/-2V and (right) +/-5V voltage ranges. -- Figure S4. TiN/20nm Ge50Se50/TiN (D21) C-V-f and G-V-f vs Temperature (T). -- Figure S5. Leakage current measured as a function of the temperature in TiN/20nmGe60Se40/TiN (D22). -- Figure S6. TiN/20nmGe60Se40/TiN (D22) C-V-f and G-V-f vs Temperature (T). -- S2. DFT accuracy tests. -- Table S3. Basis set convergence. -- Figure S7. Density of states of representative models of amorphous Ge50Se50. -- Figure S8. Density of states of representative models of amorphous Ge50Se50. -- S3 Electronic structure analysis. -- Figure S9. Total (black line) and Ge- (blue) and Se-projected (green) DOS for the twelve simulation boxes obtained from DFT relaxation for the Ge40Se60 system. -- Figure S10. Total (black line) and Ge- (blue) and Se-projected (green) DOS for the twelve simulation boxes obtained from DFT relaxation for the Ge50Se50 system. -- Figure S11. Total (black line) and Ge- (blue) and Se-projected (green) DOS for the twelve simulation boxes obtained from DFT relaxation for the Ge60Se40 system. -- Figure S12. Density of states of representative models of amorphous GexSe100-x at different Ge concentration (x). -- Figure S13. (a) Density of States (DOS) plot for Se-rich Ge40Se60 compound. (b) Single-particle charge density isosurface of a trap state in the mobility gap of Ge40Se60. Gray polyhedrons indicate ordered 3-fold and 4-fold local-order structures centered on Ge atoms., Peer reviewed

Tabla S1. Number of birds sampled from each species studied in Zapotillo, Ecuador., The mean and standard deviation (SD) of micronucleus and nuclear alterations for all included bird species are provided in this supporting information. These alterations were analyzed in the main article., Peer reviewed

For the detection of micronuclei and nuclear abnormalities, blood smears were prepared and stained with Giemsa. A total of 10,000 erythrocytes were counted on each slide., We are interested in understanding how the degradation of the dry forest in the Tumbesian region is related to an increase in genotoxic damage in birds. Our research hypothesis posited that the degradation of the dry forest would be associated with a higher frequency of micronuclei and nuclear abnormalities in the birds inhabiting these areas. To test our hypothesis, we conducted safe captures of birds in three different types of forests: natural forests, semi-natural forests, and shrub-dominated forests in the Tumbesian region. We collected blood samples from the captured birds and conducted tests for micronuclei and nuclear abnormalities in the laboratory. These genotoxic markers are sensitive indicators of DNA damage and provide information about the genetic health of the birds. This dataset is the basis of our findings., Universidad Técnica Particular de Loja PROY_CCNN_1256 PROY_CCNN_1054., Peer reviewed

8 pages. -- Figure S1. MAPSULES structural and colloidal characterization and drug release. -- Figure S2. Magnetic trapping experimental conditions. -- Figure S3. MAPSULES degradation evolution. -- Figure S4. Theoretical analysis of the absorption and scattering cross-sections and parameters for the calculation of the photothermal efficiency. -- Figure S5. In vivo biodistribution analysis by mass spectrometry. -- Figure S6. In vivo analysis of the photothermal effects without injected MAPSULES. -- Figure S7. In vivo safety analysis. -- Figure S8. Tumor progression., With the aim to locally enhance the efficacy of cancer nanotherapies, here we present metal iron based magnetoplasmonic drug-loaded nanocapsules (MAPSULES), merging powerful external magnetic concentration in the tumor and efficient photothermal actuation to locally boost the drug therapeutic action at ultralow drug concentrations. The MAPSULES are composed of paclitaxel-loaded polylactic-co-glycolic acid (PLGA) nanoparticles partially coated by a nanodome shape iron/silica semishell. The iron semishell has been designed to present a ferromagnetic vortex for incorporating a large quantity of ferromagnetic material while maintaining high colloidal stability. The large iron semishell provides very strong magnetic manipulation via magnetophoretic forces, enabling over 10-fold higher trapping efficiency in microfluidic channels than typical superparamagnetic iron oxide nanoparticles. Moreover, the iron semishell exhibits highly damped plasmonic behavior, yielding intense broadband absorbance in the near-infrared biological windows and photothermal efficiency similar to the best plasmonic nanoheaters. The in vivo therapeutic assays in a mouse xenograft tumor model show a high amplification of the therapeutic effects by combining magnetic concentration and photothermal actuation in the tumor, leading to a complete eradication of the tumors at ultralow nanoparticle and drug concentration (equivalent to only 1 mg/kg PLGA nanoparticles containing 8 μg/kg of paclitaxel, i.e., 100–500-fold lower than the therapeutic window of the free and PLGA encapsulated drug and 13–3000-fold lower than current nanotherapies combining paclitaxel and light actuation). These results highlight the strength of this externally controlled and amplified therapeutic approach, which could be applied to locally boost a wide variety of drugs for different diseases., Peer reviewed

12 pages. -- Fig. S1. Electronic band structures (top) and periodic atomic structures (bottom). -- Fig. S2. Atomically-resolved spin population maps (spin-up: blue; spin-down: red) for B-mv-2DCP. -- Fig. S3. Electronic density of states (DOS) plots for in the FM (left) and AFM (right) configurations for N-mv-2DCP. -- Fig. S4. Atomically-resolved spin population maps. -- Fig. S5. Atomically-resolved spin population maps for cyclo-para-phenylmethine (analog molecular cycle of C-2DCP). -- Fig. S6. Singly occupied natural orbitals (SONO) for the singlet ground state of the CB- model with two magnetic centres. -- Fig. S7. Average of the absolute atomically-partitioned αC spin population, 〈|𝜇𝛼𝐶|〉, during 3 ps of an ab initio molecular dynamics (AIMD) simulation of N-mv-2DCP at 300 K using the PBE0 functional. -- Fig. S8. Z-view (top) and y-view (bottom) of the fully optimized atomic structures (both atomic coordinates and cell parameters) for the ox-N-mv-2DCP, N-mv-2DCP and Cl-N-mv-2DCP. -- Fig. S9. Species-projected electronic density of states (PDOS) plots for: ox-N-mv-2DCP (left), N-mv-2DCP (middle) and Cl-N-mv-2DCP (right) per unit cell for the FM solution. -- Fig. S10. Estimated variance of U/t in ox-N-mv-2DCP, N-mv-2DCP and Cl-N-mv-2DCP assuming a single band Hubbard model on a 2D triangular lattice (i.e. the emergent lattice of αC centres). -- Magnetic coupling constant calculations. -- Fig. S11. Magnetic solutions used to extract the magnetic coupling constants described in the text. -- Rationalizing of CN- and CB- differences via molecular orbital diagrams., Two-dimensional conjugated polymers (2DCPs)organic 2D materials composed of arrays of carbon sp2 centers connected by π-conjugated linkersare attracting increasing attention due to their potential applications in device technologies. This interest stems from the ability of 2DCPs to host a range of correlated electronic and magnetic states (e.g., Mott insulators). Substitution of all carbon sp2 centers in 2DCPs by nitrogen or boron results in diamagnetic insulating states. Partial substitution of C sp2 centers by B or N atoms has not yet been considered for extended 2DCPs but has been extensively studied in the analogous neutral mixed-valence molecular systems. Here, we employ accurate first-principles calculations to predict the electronic and magnetic properties of a new class of hexagonally connected neutral mixed-valence 2DCPs in which every other C sp2 nodal center is substituted by either a N or B atom. We show that these neutral mixed-valence 2DCPs significantly energetically favor a state with emergent superexchange-mediated antiferromagnetic (AFM) interactions between C-based spin-1/2 centers on a triangular sublattice. These AFM interactions are surprisingly strong and comparable to those in the parent compounds of cuprate superconductors. The rigid and covalently linked symmetric triangular AFM lattice in these materials thus provides a highly promising and robust basis for 2D spin frustration. As such, extended mixed-valence 2DCPs are a highly attractive platform for the future bottom-up realization of a new class of all-organic quantum materials, which could host exotic correlated electronic states (e.g., unusual magnetic ordering, quantum spin liquids)., Peer reviewed

[Description of methods used for collection/generation of data] Crystal structures were characterized by powder X-ray diffraction (XRD) at room temperature in a Rigaku D-Max system using Cu Kα1,2 wavelengths. Rietveld analysis of the X-ray patterns was performed using the Fullprof package program. Electrical and electrocaloric properties measurements were conducted on sintered disc-shaped samples, with typical dimensions of 8 mm diameter and thickness between 0.5 and 1 mm. Electrodes were made with silver paste in sandwich geometry. The dielectric constant was derived from measurements with an impedance analyzer (Wayne Kerr Electronics 6500B), applying sinusoidal excitations of 1 V amplitude at several frequencies between 100 Hz and 4 MHz. The polarization versus electric field P(E) curves were recorded using a commercial polarization analyzer (aixACCT Easy Check 300) jointly with a high voltage amplifier (Trek 610E), applying sinusoidal excitations with typical frequency of 10 Hz and E field amplitudes up to 70 kV/cm. Direct measurements of the electrocaloric effect (ECE) were performed using a dedicated in-house-developed quasi-adiabatic calorimeter. The adiabatic temperature change was measured as a function of temperature every 1 K and at different applied E field variations. Samples were measured in the “contactless” mode to minimize heat losses, held only by the high voltage coaxial cable and K-type thermocouple for the direct measurement of the temperature variation. Voltages up to either 2 kV or 5 kV were applied using two different homemade high-voltage converters. Heat capacity measurements were also performed, using a commercial adiabatic calorimeter (from Termis Ltd.)., [Methods for processing the data] For the indirect estimation of the electrocaloric effect, well-known thermodynamic formulations based on Maxwell relations have been applied to the polarization data recorded at several temperatures, to derive entropy variations as a function of temperature., La and Nb codoping of the five-layer Aurivillius phase Sr2Bi4Ti5O18 induces compositional disorder and diffuse relaxor transitions at much lower temperatures than the undoped ferroelectric compound (560 K), while preserving the orthorhombic structure. For moderate La and Nb concentrations, the ferroelectric properties are enhanced in the vicinity of room temperature, and so is their electrocaloric effect measured directly with a homemade quasi-adiabatic calorimeter. The adiabatic temperature change reaches, e.g., ΔT ⁓ 0.3 K at 355 K with a temperature span ⁓ 15 K, under ΔE = 37 kV/cm. The large field dispersion of the effect is ascribed to field-induced transitions from short-range-ordered relaxor to long-range-ordered ferroelectric states. Indirect estimations of the electrocaloric effect from electric polarization data are not able to quantitatively predict the direct results and emphasize the need of applying direct measurement methods, especially for relaxor ferroelectrics., Marie Skłodowska-Curie grant agreement No. 101029019; Ministerio de Ciencia, Innovación y Universidades (PID2021-124734OB-C21); Diputación General de Aragón (E11-23R, E12-23R)., SBLTN_Fig2_XRay.dat SBLTN_Fig3a_DielectricConstant.dat SBLTN_Fig3b_DielectricConstant.dat SBLTN_Fig4a_DielectricConstant.dat SBLTN_Fig4b_DielectricConstant.dat SBLTN_Fig5_Polarization.dat SBLTN_Fig6a_Polarization.dat SBLTN_Fig6b_Polarization.dat SBLTN_Fig6c_Polarization.dat SBLTN_Fig6d_Polarization.dat SBLTN_Fig7a_DeltaT.dat SBLTN_Fig7b_DeltaT.dat SBLTN_Fig7c_DeltaT.dat SBLTN_Fig7d_DeltaT.dat SBLTN_FigS1_XRay.dat SBLTN_FigS2_XRay.dat SBLTN_FigS3_XRay.dat SBLTN_FigS4_XRay.dat SBLTN_FigS5a_Polarization.dat SBLTN_FigS5b_Polarization.dat SBLTN_FigS6a_Polarization.dat SBLTN_FigS6b_Polarization.dat SBLTN_FigS6c_Polarization.dat SBLTN_FigS6d_Polarization.dat SBLTN_FigS7a_Polarization.dat SBLTN_FigS7b_Polarization.dat SBLTN_FigS7c_Polarization.dat SBLTN_FigS7d_Polarization.dat SBLTN_FigS8_DirectECE.dat SBLTN_FigS9_DirectECE.dat SBLTN_FigS10_HeatCapacity.dat, Peer reviewed

8 pages. -- Table S1: Cerium content by organ and days, given in µg Ce/g tissue and % of injected dose. -- Figure S1: Cerium excretion in µg Ce/g tissue between day 1 and day 100. -- Figure S2: Mice weight evolution up to 30 days after nanoceria administration. -- Figure S3: Dissolution of CeO2 Nanoparticles at pH 1.7. -- Figure S4: PourBoix diagram; Figure S5: The liver and spleen are major targets for nanoparticles in CCl4-treated rats. -- Extended Materials and Methods., Peer reviewed

11 pages. -- Supplementary Figures: Figure S1. Pictures of sensor fabrication steps. -- Figure S2. Visible spectra, pictures, and micrographs of the 4 liquid phase exfoliated TMDs. -- Figure S3. SEM micrographs and EDX mapping of the only-rGO film and sensor. -- Figure S4. XPS analysis for GO and rGO films. -- Figure S5. Cyclic voltammograms obtained with the full set of sensors in phosphate buffer, [Fe(CN)6] 3-/4-and [Ru(NH3)6]2+/3+. -- Figure S6. DP and CAT differential pulse voltammograms and H2O2 hydrodynamic amperometry obtained with the full set of sensors. -- Figure S7. Differential pulse voltammetry currents of consecutive measures of DP and CAT. -- Figure S8. Differential pulse voltammograms in SCF and amperometric curves in fetal bovine serum. -- Supplementary Tables. -- Table S1. Real sample analysis data. -- Table S2. State of the art of TMDs combined with laser-induced graphenic structures., Peer reviewed

9 pages. -- Table S1. Physical properties of all materials at 300K used in the finite element method simulations. -- Table S2. Internal resistance (R) of devices with hollow and filled thermoelectric legs assuming the temperature gradient (Tvarying) and without the temperature gradient (Tfixed) as well as the percentage between the two values. -- Figure S1. Relative percentage increase for G, R, and S as a function of the thermoelectric length. -- Figure S2. The (a) G, (b) R, and (c) S with filled and hollow thermoelectric leg geometries as a function of the thermoelectric leg cross-sectional area. -- Figure S3. Temperature profile along the TEG with filled and hollow thermoelectric legs geometries when a temperature difference of 100 K is applied on the devices. -- Figure S4. Temperature profile along the TEG with length of the thermoelectric legs at 0.2 mm for filled and hollow thermoelectric legs geometries cases. -- Figure S5. Open circuit voltage and output power as a function of the electrical current for the TEG with filled and hollow thermoelectric legs. -- Figure S6. Temperature profile along the TEG with hollow thermoelectric legs geometries measured at two different points., Thermoelectric materials capable of converting heat into electrical energy are used in sustainable electric generators, whose efficiency has been normally increased with incorporation of new materials with high figure of merit (ZT) values. Because the performance of these thermoelectric generators (TEGs) also depends on device geometry, in this study we employ the finite element method to determine optimized geometries for highly efficient miniaturized TEGs. We investigated devices with similar fill factors but with different thermoelectric leg geometries (filled and hollow). Our results show that devices with legs of hollow geometry are more efficient than those with filled geometry for the same length and cross-sectional area of thermoelectric legs. This behavior was observed for thermoelectric leg lengths smaller than 0.1 mm, where the leg shape causes a significant difference in temperature distribution along the device. It was found that for reaching highly efficient miniaturized TEGs, one has to consider the leg geometry in addition to the thermal conductivity., Peer reviewed

13 pages. -- Supplementary Experimental: Supplementary physicochemical characterization of GO and GO:BTZ complex. -- Image analysis and classification. -- Figure S1. Non-covalent GO:BTZ complex formation and determination of BTZ loaded in complex. -- Figure S2. BTZ release profile in water from GO:BTZ complex measured by UV-vis after 0h, 4h or 24h in water. -- Figure S3. Physicochemical characterization of GOc and GO:BTZ complex. -- Figure S4. GO and GO:BTZ nanosheet suspension characteristics in serum (10% FBS) for 24hrs. -- Figure S5. GO-BTZ forms a necrotic zone extending from the GO injection site. -- Figure S6. Kinetics of GO:BTZ induced necrosis with direct comparison to free BTZ. -- Figure S7. Characterisation of the U87 and GL261 tumor models. -- Figure S8. GO-BTZ forming a significant necrotic core within the injected tumor area. -- Figure S9. Representative Orbit image classification. -- Figure S10. Longitudinal assessment of treatment effect and biosafety. -- Table S1: Physicochemical properties of GO sheets including lateral dimension, thickness, optical properties, surface charge and chemical composition., Peer reviewed