BUSCADOR RECOLECTA

[Methods] Firstly, in a field experiment we sampled the abundance of several grasshopper species in patches after broadcasting repeatedly for several days either little owls’ alarm calls (alarm treatment, simulating scared owls) or non-alarm/contact calls (non-alarm treatment, simulating non-scared owls), or just visiting the patches (control treatment, simulating no owls). In addition, in a mesocosm experiment, we recorded the distribution of migratory locusts (Locusta migratoria) in exposed and sheltered areas before and after broadcasting little owls´ alarm calls (alarm treatment), non-alarm/contact calls (non-alarm treatment) or vocalizations of a woodpigeon (Columba palumbus) as a granivorous, non-predator bird for grasshoppers (control treatment). The abundance of grasshoppers in the field experiment were sampled in all patches by counting all detected individuals, either inactive or during their flights/jumps, while walking at constant speed (about 2 km per hour) along longitudinal transects 50 m long and with a 5-m band. The number of grasshoppers was used as the response variable to the call treatment because it is a proxy of insect abundance as prey of little owls. In the mesocosm experiment, locusts behavior was recorded with video cameras and we counted the proportion of individuals in exposed areas at the end of pre-treatment and treatment conditions (day 1st and 2nd of the trials) and calculated the difference as a measure of preference to be exposed versus hidden in response to the call treatments., Alarm calls produced by basal prey have well-known informative value. In multipredator communities, mesopredators, when faced with top predators, may emit alarm calls that could inform basal prey about their lowered predation risk. To test this unexplored possibility, we conducted one field and one mesocosm experiment in which we simulated alarm and non-alarm calls from little owls (Athene noctua) as mesopredators and measured their effects on grasshoppers as prey of little owls but not of top predators. In the field experiment, we found that grasshopper species were significantly more abundant in patches where we simulated either the presence of scared little owls (alarm treatment) or no owls (control treatment) compared to patches where the presence of non-scared little owls (non-alarm treatment) was simulated. In the mesocosm experiment, locusts’ (Locusta migratoria) moved significantly more to exposed areas when we simulated the presence of scared little owls (alarm treatment) or of a granivorous bird (control treatment), while they moved to sheltered areas when we simulated the presence of non-scared owls (non-alarm treatment). These results show that prey could cue on predators’ calls to assess their predation risk and make decisions, revealing unprecedented potential ecological consequences of alarm calls in invertebrate communities., Ministerio de Ciencia, Innovación y Universidades, Award: CGL2014-56769-P. Spanish Ministry of Economy and Competitiveness, Award: CGL2017-83503-P. Government of Extremadura, Award: TA13002. Ministerio de Ciencia, Innovación y Universidades, Award: FJCI-2015-26257, Juan de la Cierva-Formación Fellowship., Peer reviewed

Research on High-Field Magnetic Resonance Imaging (HF-MRI) has increased in recent years, aiming to improve diagnosis accuracy by increasing the signal-to-noise ratio and hence image quality. Conventional contrast agents (CAs) have important limitations for HF-MRI, with the consequent need for the development of new CAs. Among the most promising alternatives are those based on Dy3+ or Ho3+ compounds. Notably, the high atomic number of lanthanide cations would bestow a high capability for X-ray attenuation to such Dy or Ho-based compounds, which would allow them to be also employed as CAs for X-ray computed tomography (CT). In this work, we have prepared uniform NaDy(WO4)2 and NaHo(WO4)2 nanoparticles NPs, which were dispersible under conditions that mimic the physiological media and were nontoxic for cells, meeting the main requirements for their use in vivo. Both NPs exhibited satisfactory magnetic relaxivities at 9.4T, thus making them a promising alternative to clinical CAs for HF-MRI. Furthermore, after their intravenous administration in tumor-bearing mice, both NPs exhibited significant accumulation inside the tumor at 24 h, attributable to passive targeting by the Enhanced Permeability and Retention (EPR) effect. Therefore, our NPs are suitable for detection of tumors through HF-MRI. Finally, NaDy(WO4)2 NPs showed a superior X-ray attenuation capability than iohexol (commercial CT CA), which, along with their high r2 value, makes them suitable as dual-probe for dual HF-MRI and CT imaging, as demonstrated by in vivo experiments conducted using healthy mice., This publication is part of the I + D + I Grants PID2021-122328OB-I00 and PID2020-118448RB-C21, funded by MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe”. This work was supported as well by Junta de Andalucía under grant no. P20_00182, co-financed by EU FEDER funds. Grant PRE2019-090170 funded by MCIN/AEI/10.13039/501100011033 and by “ESF Investing in your future” is also acknowledged., Elisabet Gómez-González, Carlos Caro, Nuria O. Núñez, Daniel González-Mancebo, Jesús D. Urbano-Gámez, María L. García-Martín and Manuel Ocaña. Sodium lanthanide tungstate-based nanoparticles as bimodal contrast agents for in vivo high-field MRI and CT imaging. Journal of Materials Chemistry B [In press], Peer reviewed

Peer reviewed

[ES] El catálogo incluye tantos las fechas de los eventos como las del día previo y posterior en un listado junto al mapeado de cada uno de ellos en cartografías individuales (3 por cada evento) donde se incluyen todos los observatorios en la misma fecha que registraron el máximo mensual de precipitación, fuese cual fuese su magnitud. [ES] The catalogue includes the dates of the events as well as those of the previous and following day in a list together with the mapping of each of them in individual cartographies (3 for each event) where all the observatories on the same date that recorded the maximum monthly precipitation, whatever its magnitude, are included., [ES] "Extraordnary_Daily_Precipitation_Catalogue_of_Spain_1916-2022, v.1.0.0. [Dataset]" es un catálogo de eventos de lluvia extraordinaria sucedidos a escala diaria superiores a 100 mm y 200 mm obtenido a partir de los Libros Resúmenes Anuales, editados por los sucesivos Servicios Meteorológicos de España en el periodo 1916-1950 y los fondos documetales del Banco Nacional de Datos Climáticos de AEMET., [EN] “Extraordinary_Daily_Precipitation_Catalogue_of_Spain_1916-2022, v.1.0.0. [Dataset]” is a catalog of daily extraordinary rainfall events greater than 100 mm and 200 mm obtained from the Annual Summary Books, edited by the successive Meteorological Services of Spain in the period 1916-1950 and the documentary collections of the National Climatic Data Bank of AEMET., Project PID2020-116860RB-C22: Extremos térmicos y pluviométricos en la España peninsular 1916-2020), funded by the Spanish Ministry of Science, No

TUdi - Transforming Unsustainable management of soils in key agricultural systems in EU and China. Developing an integrated platform of alternatives to reverse soil degradation. Referencia del proyecto: 101000224. Partner/Coordinador principal: José Alfonso Gómez Calero – Instituto de Agricultura Sostenible IAS- CSIC., Dataset of soil properties from the TUdi/Vinedivers vineyard management experiments in Austria., TUdi – Transforming Unsustainable management of soils in key agricultural systems in EU and China. Developing an integrated platform of alternatives to reverse soil degradation.-- Data manager: Bauer Thomas., Peer reviewed

The dataset contains 3 files.-- Information on the methodology and quality control can be found in the files description and references included in the README_NWIberian_DO_1969_2018_V02.txt file, The dataset NWIberian_DO_1969_2018_V02 contains: averaged yearly data from compiled datasets of dissolved oxygen concentration, temperature and salinity at the 27.1 isopycnal level from different cruises between 1969 and 2018, and covering the area 40°- 43°N and 9°-11°W; time series of the potential drivers of the dissolved oxygen change in the region of ENACW formation (45°- 49°N and 9°-20°W) and off the NW Iberian coast (40°- 43°N and 9°-11°W); distributions of sea surface temperature over the area 39°- 55°N and 6°-30°W and averaged over differente time periods; and table with examples from other upwelling regions in terms of concentration and trends of dissolved oxygen, Funding for this dataset was provided by the Spanish Ministry of Science and Innovation through a Personal Técnico de Apoyo grant (PTA2019-017492-I) and the CAPTA project (CAPTA 0062_CAPTA_1_E, POCTEP 2021-2027), ENACWsptseries19692018V02.csv.-- SST_NAtlantic.csv.-- Oxygen_upwelling_systems.csv.-- README_NWIberian_DO_1969_2018_V02.txt, No

The ALBA Synchrotron is funded by the Ministry of Research and Innovation of Spain, by the Generalitat de Catalunya and by European FEDER funds. This work has been supported by Spanish MCIN/AEI/10.13039/501100011033/FEDER,UE under grants PID2019-104604RB and PID2022-136784NB and by Asturias FICYT under grant AYUD/2021/51185 with the support of FEDER funds., Peer reviewed

Additional file1: Supplementary table 1. Pyrosequencing results for the affected family and controls., Peer reviewed

We report the synthesis, spectroscopic properties, and anti-proliferative efficacy of the adamantane-linked 1,2,4-triazole derivative 5-(adamantan-1-yl)-4-(3-chlorophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione. Crystal packing and intermolecular interactions have been quantified using Hirshfeld surfaces and two-dimensional fingerprint plots. ADMET characteristics, bioavailability, and drug-likeness define the compound’s bioactivity. The gastrointestinal absorption is anticipated to be high, and the projected bioavailability score is 0.55. The topological polar surface area and iLOGP, XLOGP, WLOGP, and MLOGP lipophilicity parameters have been calculated to be 65.70 Å2, 3.24, 4.74, 5.05, and 4.07, respectively. To investigate 5A4ClT's EGFR inhibition and its use in the treatment of non-small cell lung cancer, Autodock Vina was used to dock it with the crystal structure of the EGFR kinase domain protein. The title chemical hydrophobically interacts with the receptor residues LEU718, VAL726, ALA743, GLU762, THR790, LEU792, MET793, GLY796, ARG841, ASN842, and LEU844 and forms hydrogen bonds with ASP855 and THR854 with an affinity of −8.3 kcal/mol. Toxicity end points and comparison with NSCLC drugs yielded promising findings. 120 ns molecular dynamics simulations confirmed the ligand’s dynamic stability in the target protein’s binding pocket. This research lays the groundwork for future in vivo investigations of 5A4ClT as a non-small cell lung cancer therapy., This research was funded by Princess Nourah bint Abdulrahman University Researchers Supporting Project No. (PNURSP2023R3), Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia., Peer reviewed

In this manuscript, we demonstrate a new approach to develop highly transparent thin films with effective refractive index close to unity that can be easily generalized to create highly performing photonic materials. Central to the procedure herein proposed is the used of sacrificial polymer nanosphere thin films that can be coated by chemical vapor deposition with thin interconnected shells of metal oxides, which gives rise to ultralow refractive index slabs upon removal of the organic template. The method herein presented is compatible with the processing techniques employed for other nanomaterials, which allows us to over-come the challenge of integrating ultralow refractive index materials into more complex photonic architectures. As proofs-of-principle of their potential significance in the field of photonics, we show how to obtain (i) a very thin film acting as a highly diffusive random optical medium, which results from the high refractive index contrast between the air-like refractive index film and spherical scatterers dispersed in it, and (ii) a film loaded with nanophosphors displaying enhanced photoluminescence out-coupling, as a result of the reduced light guiding losses achieved by the low dielectric contrast between the host of the emitters and the surrounding environment., This project received funding from the Spanish Ministry of Science and Innovation under grant PID2020-116593RB-I00, funded by MCIN/AEI/10.13039/501100011033, the Junta de Andalucía under grant P18-RT-2291 (FEDER/UE), and the European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation Programme (NANO-PHOM, grant agreement no. 715832)., Figure 2: - Data_2d_RT_exp_1cy.txt - Data_2d_RT_exp_2cy.txt - Data_2d_RT_exp_3cy.txt - Data_2d_RT_the_1cy.txt - Data_2d_RT_the_2cy.txt - Data_2d_RT_the_3cy.txt - Data_2e_nk_1cy.txt - Data_2e_nk_2cy.txt - Data_2e_nk_3cy.txt - Data_2f_1cy.txt - Data_2f_2cy.txt - Data_2f_3cy.txt - Data_2f_glass.txt Figure 3: - Data_3d_r_146nm.txt - Data_3d_r_188nm.txt - Data_3d_r_225nm.txt - Data_3d_r_250nm.txt - Data_3e_r_146nm.txt - Data_3e_r_146nm_air.txt - Data_3e_r_188nm.txt - Data_3e_r_188nm_air.txt - Data_3e_r_225nm.txt - Data_3e_r_225nm_air.txt - Data_3e_r_250nm.txt - Data_3e_r_250nm_air.txt Figure 4: - Data_4c_corrected_PL.txt - Data_4d_theoretical_outcouplig_versus_refractive_index.txt, Peer reviewed