Resultados totales (Incluyendo duplicados): 33526
Encontrada(s) 3353 página(s)
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311509
Dataset. 2022

HMG20A-PHF14 MODEL-1

  • Reyes, José C.
  • Guerrero-Martínez, José A.
Material For modeling AlphaFold2_multimer was used. AlphaFold2 was downloaded from https://github.com/deepmind/alphafold/releases. Full length amino acid sequences of human PHF14 and HMG20A were used: >NP_001291433.1 high mobility group protein 20A isoform a [Homo sapiens] >NP_001007158.1 PHD finger protein 14 isoform 1 [Homo sapiens] To perform PHF14-HMG20A complex models we used Alphafold_multimers (v2.1.1) with --db_preset=reduced_dbs, --model_preset=multimer --max_template_date=2021-11-01, and default parameters. Computation was performed in the CESGA Supercomputing Center. RCSB PDB (https://www.rcsb.org/3d-view) or Swiss PDB viewer (DeepView) were used for structure viewing. Procedure Full lenth amino-acid protein sequences were obtained form NCBI Protein. Then, to perform PHF14-HMG20A complex models we used Alphafold_multimers (v2.1.1) with --db_preset=reduced_dbs, --model_preset=multimer --max_template_date=2021-11-01, and default parameters. A PAE plot (Predicted Aligned Error Plot) is uploaded. PAE plot "reports AlphaFold’s expected position error at residue x, when the predicted and true structures are aligned on residue y. This is useful for assessing confidence in global features, especially domain packing. For residues x and y drawn from two different domains, a consistently low PAE at (x, y) suggests AlphaFold is confident about the relative domain positions" (https://deepmind.com/research/publications/2021/enabling-high-accuracy-protein-structure-prediction-at-the-proteome-scale). A distogram (Matrix of distances between different parts of the proteins) is also uploaded., Structural modeling by using the AlphaFold2_multimer software, indicated that HMG20A forms a complex with PHF14 through the establishment of a two-stranded alpha-helical coiled-coil structure, Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311509
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311509
HANDLE: http://hdl.handle.net/10261/311509
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311509
PMID: http://hdl.handle.net/10261/311509
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311509
Ver en: http://hdl.handle.net/10261/311509
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311509

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311516
Dataset. 2022

SUPPLEMENTARY INFORMATION FROM A CULTURAL EVOLUTIONARY THEORY THAT EXPLAINS BOTH GRADUAL AND PUNCTUATED CHANGE

  • Vidiella, Blai
  • Carrignon, Simon
  • Bentley, R. Alexander
  • O’Brien, Michael J.
  • Valverde, Sergi
Cumulative cultural evolution (CCE) occurs among humans who may be presented with many similar options from which to choose, as well as many social influences and diverse environments. It is unknown what general principles underlie the wide range of CCE dynamics and whether they can all be explained by the same unified paradigm. Here, we present a scalable evolutionary model of discrete choice with social learning, based on a few behavioural science assumptions. This paradigm connects the degree of transparency in social learning to the human tendency to imitate others. Computer simulations and quantitative analysis show the interaction of three primary factors—information transparency, popularity bias and population size—drives the pace of CCE. The model predicts a stable rate of evolutionary change for modest degrees of popularity bias. As popularity bias grows, the transition from gradual to punctuated change occurs, with maladaptive sub-populations arising on their own. When the popularity bias gets too severe, CCE stops. This provides a consistent framework for explaining the rich and complex adaptive dynamics taking place in the real-world, such as modern digital media., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311516
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311516
HANDLE: http://hdl.handle.net/10261/311516
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311516
PMID: http://hdl.handle.net/10261/311516
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311516
Ver en: http://hdl.handle.net/10261/311516
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311516

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311517
Dataset. 2022

CRYPTO WHITE PAPERS DOCUMENTS

  • Valverde, Sergi
  • Durán Nebreda, Salva
This is the database used in the script 'information_density_whitepapers'., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311517
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311517
HANDLE: http://hdl.handle.net/10261/311517
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311517
PMID: http://hdl.handle.net/10261/311517
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311517
Ver en: http://hdl.handle.net/10261/311517
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311517

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311518
Dataset. 2022

OPTICS PUBLICATIONS DATASET

  • Durán Nebreda, Salva
  • Valverde, Sergi
This dataset includes the publication date of all the collected articles in the field of optics, as well as their file name and DOI., AGAUR 2019 BP 00206. Grant PID2020-117822GB-I00 funded by MCIN/AEI/10.13039/501100011033 and, as appropriate, by “ERDF A way of making Europe”, by the “European Union” or by the “European Union NextGenerationEU/PRTR”., Peer reviewed

DOI: http://hdl.handle.net/10261/311518
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311518
HANDLE: http://hdl.handle.net/10261/311518
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311518
PMID: http://hdl.handle.net/10261/311518
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311518
Ver en: http://hdl.handle.net/10261/311518
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311518

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311519
Dataset. 2022

CRYPTOCURRENCIES DATASET

  • Durán Nebreda, Salva
  • Valverde, Sergi
This dataset includes the release date of all the collected cryptocurrency whitepapers, as well as their file name, size and compressed size., AGAUR 2019 BP 00206. Grant PID2020-117822GB-I00 funded by MCIN/AEI/10.13039/501100011033 and, as appropriate, by “ERDF A way of making Europe”, by the “European Union” or by the “European Union NextGenerationEU/PRTR”., Peer reviewed

DOI: http://hdl.handle.net/10261/311519
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311519
HANDLE: http://hdl.handle.net/10261/311519
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311519
PMID: http://hdl.handle.net/10261/311519
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311519
Ver en: http://hdl.handle.net/10261/311519
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311519

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311520
Dataset. 2022

EXAMPLE SCRIPTS

  • Durán Nebreda, Salva
  • Valverde, Sergi
These are example scripts for processing data for the publication "Dilution of expertise in the rise and fall of collective innovation". Requires Pyhton 3.8 and XCODE for macOS 11.3. Dependence on open-sorce library glfw 3.3.3 and OpenGL., AGAUR 2019 BP 00206. Grant PID2020-117822GB-I00 funded by MCIN/AEI/10.13039/501100011033 and, as appropriate, by “ERDF A way of making Europe”, by the “European Union” or by the “European Union NextGenerationEU/PRTR”., Peer reviewed

DOI: http://hdl.handle.net/10261/311520
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311520
HANDLE: http://hdl.handle.net/10261/311520
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311520
PMID: http://hdl.handle.net/10261/311520
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311520
Ver en: http://hdl.handle.net/10261/311520
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311520

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311521
Dataset. 2022

CRYPTOCURRENCY WHITEPAPER NETWORKS

  • Durán Nebreda, Salva
  • Valverde, Sergi
This zip file contains the processed bipartite networks of word-sentence associations for all compiled cryptocurrency whitepapers until 2020., AGAUR BP 2019 00206. Grant PID2020-117822GB-I00 funded by MCIN/AEI/10.13039/501100011033 and, as appropriate, by “ERDF A way of making Europe”, by the “European Union” or by the “European Union NextGenerationEU/PRTR”., Peer reviewed

DOI: http://hdl.handle.net/10261/311521
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311521
HANDLE: http://hdl.handle.net/10261/311521
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311521
PMID: http://hdl.handle.net/10261/311521
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311521
Ver en: http://hdl.handle.net/10261/311521
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311521

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311533
Dataset. 2023

SUPPLEMENTARY MATERIALS FOR PEPTIDOMIC CHARACTERIZATION AND AMINO ACID AVAILABILITY AFTER INTAKE OF CASEIN VS. A CASEIN HYDROLYSATE IN A PIG MODEL

  • Jiménez-Barrios, Pablo
  • Sánchez Rivera, Laura
  • Martínez-Maqueda, D.
  • Le Gouar, Yann
  • Dupont, Didier
  • Miralles, Beatriz
  • Recio, Isidra
The supporting information: Figure S1: Electrophoretic profile of pig duodenal effluents at different times of digestion after intake of casein and hydrolysate compared with the given substrate; Figure S2: Identified peptides in pig duodenal digests after intake of casein or hydrolysate over collection time represented by area graphs; Figure S3: Alignment of peptides identified in pig duodenal effluents collected at different times of digestion after intake of casein or hydrolysate and represented as heatmaps of β-casein and αS1-casein; Figure S4: SeqLogo analysis of terminal amino acid residues corresponding to the peptides identified in pig duodenal effluents at all times of digestion after intake of casein or hydrolysate; Figure S5: Total amino acids and metabolites determined in plasma after intake of casein or hydrolysate in the pig model; Figure S6: Concentration of amino acids in plasma of pigs (n = 6) at baseline (−15 min) and 5, 20, 45, 60, 120, 180, 240 and 360 min after intake of casein or hydrolysate. Table S1: Pig endogenous proteins identified in the analyzed duodenal effluents. Full PermutMatrix results are shown as an attached figure in .png format., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311533
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311533
HANDLE: http://hdl.handle.net/10261/311533
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311533
PMID: http://hdl.handle.net/10261/311533
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311533
Ver en: http://hdl.handle.net/10261/311533
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311533

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311537
Dataset. 2023

FIGURES AND DATA OF SACHA INCHI OIL PRESS-CAKE: PHYSICOCHEMICAL CHARACTERISTICS, FOOD-RELATED APPLICATIONS AND BIOLOGICAL ACTIVITY

  • Torres Sánchez, Erwin G.
  • Hernández-Ledesma, Blanca
  • Gutiérrez, Luis-Felipe
Table 1. Mean composition of Sacha Inchi (Plukenetia ssp.) oil press-cake according to bibliographic data. Table 2. Amino acid profile of SIOPC according to bibliographic data., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311537
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311537
HANDLE: http://hdl.handle.net/10261/311537
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311537
PMID: http://hdl.handle.net/10261/311537
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311537
Ver en: http://hdl.handle.net/10261/311537
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311537

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311554
Dataset. 2023

JAK1 INHIBITION WITH ABROCITINIB DECREASES ALLERGEN-SPECIFIC BASOPHIL AND T CELL ACTIVATION IN PEDIATRIC PEANUT ALLERGY [DATASET]

  • Ramsey, Nicole
  • Kazmi, Wajiha
  • Phelan, Matthew
  • Lozano-Ojalvo, Daniel
  • Berin, M. Cecilia
Supplementary Material Online Repository., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311554
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311554
HANDLE: http://hdl.handle.net/10261/311554
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311554
PMID: http://hdl.handle.net/10261/311554
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311554
Ver en: http://hdl.handle.net/10261/311554
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311554

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