Resultados totales (Incluyendo duplicados): 45302
Encontrada(s) 4531 página(s)
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331193
Dataset. 2022

SUPPLEMENTARY MATERIAL CAN A MIXTURE OF AGROCHEMICALS (GLYPHOSATE, CHLORPYRIFOS AND CHLOROTHALONIL) MASK THE PERCEPTION OF AN INDIVIDUAL CHEMICAL? A HIDDEN TRAP UNDERLYING ECOLOGICAL RISK

  • Mena, Freylan
  • Romero, Adarli
  • Blasco, Julián
  • Araújo, Cristiano V. M.
2 pages. -- Supplementary figure 1: Distribution of D. rerio juveniles along the gradients of Glyphosate, Chlorpyrifos and Chlorothalonil, throughout the three-hour period of exposure to the gradient of each substance individually. -- Supplementary figure 2. Distribution of D. rerio juveniles along the gradients of a mixture of Glyphosate-Chlorpyrifos, and Glyphosate-Chlorothalonil, throughout the three-hour period of exposure in the open gradient of each mixture., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/331193
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331193
HANDLE: http://hdl.handle.net/10261/331193
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331193
PMID: http://hdl.handle.net/10261/331193
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331193
Ver en: http://hdl.handle.net/10261/331193
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331193

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331199
Dataset. 2022

SUPPLEMENTARY INFORMATION OF THE ARTICLE 2,2,3,3,3-PENTAFLUORO-1-PROPANOL AND ITS DIMER: STRUCTURAL DIVERSITY, CONFORMATIONAL CONVERSION, AND TUNNELLING MOTION

  • Wu, Bowei
  • Seifert, Nathan A.
  • Insausti, Aran
  • Ma, Jiarui
  • Oswald, Sönke
  • Jäger, Wolfgang
  • Xu, Yunjie
59 pages. -- Contents: Point S1. Gaussian keywords used in the calculations. -- Figure S1. Experimental spectra of PFPG+g+/G-g- and its isotopologues species. -- Table S1-S7. Transition frequencies of PFPG+g+/G-g- and its isotopologues and PFPTg+/Tg-. -- Figure S2. Experimental spectra of the PFPTg+/Tg- monomer. -- Figure S3. Conformational interconversion barrier of the PFP conformers. -- Table S8-S10. Kraitchamn and STRFIT results of PFPG+g+/G-g. -- Table S11-S13. The semi-experimental equilibrium structural parameters of PFPG+g+/G-g-. -- Table S14. Spectroscopic properties of the predicted binary PFP conformers. -- Table S15-S19. Rotational transition frequencies of the five binary PFP conformers. -- Figure S4. QTAIM and NCI analyses of the five PFP and PrOH conformers. -- Figure S5. QTAIM and NCI analyses of the five binary PFP conformers. -- Completion of reference 24., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/331199
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331199
HANDLE: http://hdl.handle.net/10261/331199
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331199
PMID: http://hdl.handle.net/10261/331199
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331199
Ver en: http://hdl.handle.net/10261/331199
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331199

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331205
Dataset. 2022

SUPPORTING INFORMATION BOND LENGTH ALTERNATION AND INTERNAL DYNAMICS IN MODEL AROMATIC SUBSTITUENTS OF LIGNIN

  • Hernández Castillo, Alicia Odette
  • Calabrese, Camilla
  • Fritz, Sean M.
  • Uriarte, Icíar
  • Cocinero, Emilio J.
  • Zwier, Timothy S.
29 pages. -- PDF file includes: Strong-field coherence breaking (SFCB) details; Internal rotation methyl barrier of 4-methyl guaiacol (MG). -- Figure S1: Experimental and simulated variation of the internal rotational barrier of methyl group. -- Figure S2: Summary of bond changes of lignin relative to the average bond length rC-C. -- Figure S3: Optimized structure of guaiacol at B3LYP-D3BJ/def2tzvp level of theory. -- Table S1: Experimental and calculated constants derived from the broadband rotational spectrum of guaiacol. -- Table S2: List of spectroscopic parameters used to fit guaiacol isotopomers. -- Table S3: Experimental and calculated constants derived from the broadband rotational spectrum of syringol. -- Table S4: Molecular parameters of 4-methyl guaiacol. -- Table S5: Molecular parameters for Z- and E-4-vinyl guaiacol. -- Table S6: Line list of transitions fitted for guaiacol (G). -- Table S8: Line list of transitions fitted for 13C(2) guaiacol. -- Table S9: Line list of transitions fitted for 13C(3) guaiacol. -- Table S10: Line list of transitions fitted for 13C(4) guaiacol. -- Table S11: Line list of transitions fitted for 13C(5) guaiacol. -- Table S12: Line list of transitions fitted for 13C(6) guaiacol. -- Table S13: Line list of transitions fitted for 13C(7) guaiacol. -- Table S14: Line list of transitions fitted for syringol (S). -- Table S15: Line list of transitions fitted for methyl guaiacol (MG). -- Table S16: Line list of transitions fitted for vinyl guaiacol (Z-VG). -- Table S17: Line list of transitions fitted for vinyl guaiacol (E-VG)., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/331205
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331205
HANDLE: http://hdl.handle.net/10261/331205
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331205
PMID: http://hdl.handle.net/10261/331205
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331205
Ver en: http://hdl.handle.net/10261/331205
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331205

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331206
Dataset. 2022

BOXPLOT DISTRIBUTION OF THE 3 PROTEINS SELECTED FOR VALIDATION (NT-PROBNP, ST-2 AND TIMP-2) ACCORDING TO THE METHODOLOGY USED FOR AF DIAGNOSIS

  • Palà, Elena
  • Bustamante, Alejandro
  • Clúa-Espuny, Josep Lluis
  • Acosta, Juan
  • Gonzalez-Loyola, Felipe
  • Dos Santos, Sara
  • Ribas-Segui, Domingo
  • Ballesta-Ors, Juan
  • Penalba, Anna
  • Giralt, Marina
  • Lechuga-Duran, Iñigo
  • Gentille-Lorente, Delicia
  • Pedrote, Alonso
  • Muñoz, Miguel Ángel
  • Montaner, Joan
Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/331206
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331206
HANDLE: http://hdl.handle.net/10261/331206
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331206
PMID: http://hdl.handle.net/10261/331206
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331206
Ver en: http://hdl.handle.net/10261/331206
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331206

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331208
Dataset. 2022

TOP TABLE OF THE DIFFERENTIAL EXPRESSED PROTEINS BETWEEN AF AND NO AF

  • Palà, Elena
  • Bustamante, Alejandro
  • Clúa-Espuny, Josep Lluis
  • Acosta, Juan
  • Gonzalez-Loyola, Felipe
  • Dos Santos, Sara
  • Ribas-Segui, Domingo
  • Ballesta-Ors, Juan
  • Penalba, Anna
  • Giralt, Marina
  • Lechuga-Duran, Iñigo
  • Gentille-Lorente, Delicia
  • Pedrote, Alonso
  • Muñoz, Miguel Ángel
  • Montaner, Joan
S1 Table: Top table of the differential expressed proteins between AF and no AF. Results from the discovery study., Results from the discovery study. Proteins selected to be verified in the whole Phase 1 are highlighted in grey. Proteins in bold but not highlighted were already tested in the whole phase 1 as part of a previous published work., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/331208
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331208
HANDLE: http://hdl.handle.net/10261/331208
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331208
PMID: http://hdl.handle.net/10261/331208
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331208
Ver en: http://hdl.handle.net/10261/331208
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331208

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331211
Dataset. 2022

SUPPORTING INFORMATION FOR SMALL, DOI: 10.1002/SMLL.202105915 BOOSTING CHOLESTEROL EFFLUX FROM FOAM CELLS BY SEQUENTIAL ADMINISTRATION OF RHDL TO DELIVER MICRORNA AND TO REMOVE CHOLESTEROL IN A TRIPLE-CELL 2D ATHEROSCLEROSIS MODEL

  • Jebari Benslaiman, Shifa
  • Uribe, Kepa B.
  • Benito-Vicente, Asier
  • Galicia-García, Unai
  • Larrea, Asier
  • Santin, Izortze
  • Alloza, Iraide
  • Vanderbroeck, Koen
  • Ostolaza, Helena
  • Martín, César
13 pages. -- PDF file includes: 1. Supplementary Methods: 1.1. LDL Acetylation; 1.1. Quantitative and Qualitative Analysis of Foam Cell Formation; 1.2. Immunofluorescent Imaging of Co-culture Inserts; 1.4. Western Blot Analysis. -- Supplementary Figure 1. miRNA transfer capacity by DPPC:CE:LPC rHDL to foam cells cultured in monolayer. -- Supplementary Figure 2. Combination of TO901317 and antagomiR-33a-rHDL caused a synergistic upregulation of ABCA1 and ABCG1 protein levels in foam cells. -- Supplementary Figure 3. Intracellular Cholesterol Levels in Foam Cells After TO901317 Treatment, AntagomiR-33a-rHDL Delivery or Combined Treatment of TO901317 and AntagomiR-33a-rHDL in 1D Grown Foam Cells or 2D Atheroma Model Foam Cells. -- Supplementary Figure 4. Cholesterol efflux promoted in foam cells by sequential rHDL administration in a triple cell 2D atheroma model. -- Supplementary Figure 5. Agarose gel electrophoresis of acetylated LDL (LDLac). -- Supplementary Figure 6. Quantitative and Qualitative Analysis of Foam Cell Formation. -- Supplementary Figure 7. Development of triple-compartment cell culture 2D atheroma model. -- Supplementary Figure 8. Timeline showing cholesterol efflux experimental design., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/331211
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331211
HANDLE: http://hdl.handle.net/10261/331211
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331211
PMID: http://hdl.handle.net/10261/331211
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331211
Ver en: http://hdl.handle.net/10261/331211
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331211

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331214
Dataset. 2022

ALL PATIENT DATA AND BIOMARKER MEASUREMENTS

  • Palà, Elena
  • Bustamante, Alejandro
  • Clúa-Espuny, Josep Lluis
  • Acosta, Juan
  • Gonzalez-Loyola, Felipe
  • Dos Santos, Sara
  • Ribas-Segui, Domingo
  • Ballesta-Ors, Juan
  • Penalba, Anna
  • Giralt, Marina
  • Lechuga-Duran, Iñigo
  • Gentille-Lorente, Delicia
  • Pedrote, Alonso
  • Muñoz, Miguel Ángel
  • Montaner, Joan
Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/331214
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331214
HANDLE: http://hdl.handle.net/10261/331214
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331214
PMID: http://hdl.handle.net/10261/331214
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331214
Ver en: http://hdl.handle.net/10261/331214
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331214

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331238
Dataset. 2022

APPENDIX A. SUPPLEMENTARY DATA FOR DIETARY ECOLOGY OF TWO MIGRANT FLYCATCHERS IN HABITATS WITH AND WITHOUT CATTLE DURING THE BREEDING SEASON IN CENTRAL ARGENTINA

  • Rebollo, María Emilia
  • Jahn, Alex E.
  • Stella, César Adrián
  • Pérez-Rodríguez, Lorenzo
  • Sarasola, José Hernán
  • Cereghetti, Joaquín
Multimedia component 1: Fig. S1. Espinal biome, La Pampa Province, Argentina, characterized by a) open Caldén (Prosopis caldenia) forest, b) closed Caldén forest with shrubs, and c) and d) Caldén forest with grassland. Fig. S2. Location of sites sampled to evaluate arthropod prey abundance of Vermilion Flycatchers and Fork-tailed Flycatchers in the Espinal biome, La Pampa Province, Argentina, during a) 2016–17, and b) 2017-18 and 2018-19 breeding seasons. Fig. S3. Location of sites sampled to evaluate diet of Vermilion Flycatchers (VEFL) and Fork-tailed Flycatchers (FTFL) in the Espinal biome, La Pampa Province, Argentina, during a) 2015–16, b) 2016–17, c) 2017–18 and d) 2018-19 breeding seasons. Fig. S4. Location of control and nest sites sampled to evaluate the effect of arthropod prey abundance on breeding habitat selection of Vermilion Flycatchers (VEFL) and Fork-tailed Flycatchers (FTFL) in the Espinal biome, La Pampa Province, Argentina. All arthropod abundance samples were obtained during the 2016-17 breeding season., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/331238
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331238
HANDLE: http://hdl.handle.net/10261/331238
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331238
PMID: http://hdl.handle.net/10261/331238
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331238
Ver en: http://hdl.handle.net/10261/331238
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331238

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331253
Dataset. 2022

APPENDIX A. SUPPLEMENTARY MATERIAL: IS SEROLOGY A REALISTIC APPROACH FOR MONITORING RED DEER TUBERCULOSIS IN THE FIELD?

  • Ferreras-Colino, Elisa
  • Moreno, Inmaculada
  • Arnal, Maria Cruz
  • Balseiro, Ana
  • Acevedo, Pelayo
  • Domínguez, Mercedes
  • Fernández de Luco, Daniel
  • Gortázar, Christian
  • Risalde, María Ángeles
Fig. S1. Ddiagram of flow of participants used in this study., Identification as a study of diagnostic accuracy using at least one measure of accuracy (such as sensitivity, specificity, predictive values, or AUC). Structured summary of study design, methods, results, and conclusions (for specific guidance, see STARD for Abstracts)., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/331253
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331253
HANDLE: http://hdl.handle.net/10261/331253
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331253
PMID: http://hdl.handle.net/10261/331253
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331253
Ver en: http://hdl.handle.net/10261/331253
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331253

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331254
Dataset. 2022

SUPPLEMENTARY MATERIAL FOR ARTICLE BROAD TRANSCRIPTOMIC IMPACT OF SORAFENIB AND ITS RELATION TO THE ANTITUMORAL PROPERTIES IN LIVER CANCER CELLS

  • Contreras, Laura
  • Rodríguez-Gil, Alfonso
  • Muntané, Jordi
  • Cruz, Jesús de la
Table S1. List of DEGs in Sfb-treated HepG2 and SNU423 cells. See supplementary Table S1 Excel file. Table S2. List of DEGs with log2(FC) higher than 1.5 or lower than -1.5 in Sfb-treated HepG2 and SNU423 cells. See supplementary Table S2 Excel file. Table S3. List of pathways activated or inhibited upon a Sfb treatment in HepG2 cells. See supplementary Table S3 Excel file. Figure S1. Quantitative RT-PCR validation of RNA-Seq data for HepG2 cells. A selection of down-regulated and up-regulated genes were assessed for gene expression through qPCR. Cells were grown for 24 h and then treated with 10 μM Sorafenib for 12 h before RNA extraction. The table compared the fold expression obtained by RNA-Seq versus the relative expression calculated by RT-PCR. Note that the corresponding mRNA levels quantified by RT-PCR from untreated cells (control) were arbitrarily set at 1.0. The ACTB, BAX, BIRC3, CEBP, CPEB4, DUSP1, EIF4E2, EPOP, FEN1, GADD45B, IDI1, PCNA, SMAD7, TPI and VEGFA genes were analysed. Expression levels were relativized to levels of 28S rRNA of each sample. Values are the mean ± S.D. values of at least three independent experiments performed in triplicate. Statistical significances were analysed by the Student's test (*p< 0.05, **p< 0.01, *** p< 0.001, ****p< 0.0001). Values for upregulated genes are shown in red, while those for downregulated genes are shown in green. Figure S2. Quantitative RT-PCR validation of RNA-Seq data for SNU423 cells. A selection of down-regulated and up-regulated genes were assessed for gene expression through qPCR. Cells were grown for 24 h and then treated with 10 μM Sorafenib for 12 h before RNA extraction. The table compared the fold expression obtained by RNA-Seq versus the relative expression calculated by RT-PCR. Note that the corresponding mRNA levels quantified by RT-PCR from untreated cells (control) were arbitrarily set at 1.0. The BIM, BOP1, BIRC3, CPEB4, DUSP1, EIF4E2, EPOP, GADD45B, IDI1, PHB, PCNA, SMAD7 and TPI genes were analysed. Expression levels were relativized to levels of 28S rRNA of each sample. Values are the mean ± S.D. values of at least three independent experiments performed in triplicate. Statistical significances were analysed by the Student's test (*p< 0.05, **p< 0.01, ***p< 0.001, ****p< 0.0001). Values for upregulated genes are shown in red, while those for downregulated genes are shown in green. Figure S3. Sorafenib lead to translation inhibition in HCC cells. Polysome profiles in HepG2 and SNU423 cells treated or not with Sorafenib (10 μM, 12 h). Cell extracts and polysome profile analysis were performed following the procedure described in Material and Methods. Ten A260 units of each extract were resolved in 7 to 50% sucrose gradients. The A254 was continuously monitored. Sedimentation is from left to right. The identity of the different peaks is indicated. Figure S4. Cholesterol biosynthesis pathway in humans. This outline shows the cholesterol biosynthesis process with those enzymes whose genes were down-regulated by Sfb in red as suggested by our RNA-Seq analysis. The log2(FC) for each one is indicated in brackets. Figure S5. Categories with opposite NES values in HepG2 and SNU423 cell lines. Reactome categories which show NES in opposite directions in the two cell lines analysed with the GSEA. NES and False Discovery Rate (FDR) q-Value are shown for each category. Panel (A) shows categories with FDR lower than 0.3 for HepG2 cells and its value in SNU423 cell line whereas panel (B) shows categories with FDR more significative for SNU423 cells and its respective value for HepG2 cells. Figure S6. Uncropped Western Blots., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/331254
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331254
HANDLE: http://hdl.handle.net/10261/331254
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331254
PMID: http://hdl.handle.net/10261/331254
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331254
Ver en: http://hdl.handle.net/10261/331254
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