Resultados totales (Incluyendo duplicados): 34303
Encontrada(s) 3431 página(s)
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311656
Dataset. 2022

SUPPLEMENTARY MATERIAL FOR WHOLE-GENOME RESEQUENCING OF WORLDWIDE WILD AND DOMESTIC SHEEP ELUCIDATES GENETIC DIVERSITY, INTROGRESSION AND AGRONOMICALLY IMPORTANT LOCI

  • Lv, Feng-Hua
  • Cao, Yin-Hong
  • Liu, Guang-Jian
  • Luo, Ling-Yun
  • Lu, Ran
  • Liu, Ming-Jun
  • Li, Wen-Rong
  • Zhou, Ping
  • Wang, Xin-Hua
  • Shen, Min
  • Gao, Lei
  • Yang, Jing-Quan
  • Yang, Hua
  • Yang, Yong-Lin
  • Liu, Chang-Bin
  • Wan, Peng-Cheng
  • Zhang, Yun-Sheng
  • Pi, Wen-Hui
  • Ren, Yan-Ling
  • Shen, Zhi-Qiang
  • Wang, Feng
  • Wang, Yu-Tao
  • Li, Jin-Quan
  • Salehian-Dehkordi, Hosein
  • Hehua, Eer
  • Liu, Yong-Gang
  • Chen, Jian-Fei
  • Wang, Jian-Kui
  • Deng, Xue-Mei
  • Esmailizadeh, Ali
  • Dehghani-Qanatqestani, Mostafa
  • Charati, Hadi
  • Nosrati, Maryam
  • Štěpánek, Ondřej
  • Rushdi, Hossam E.
  • Olsaker, Ingrid
  • Curik, Ino
  • Gorkhali, Neena A.
  • Paiva, S. R.
  • Caetano, Alexander R.
  • Ciani, Elena
  • Amills, Marcel
  • Weimann, Christina
  • Erhardt, Georg
  • Amane, Agraw
  • Mwacharo, Joram M.
  • Han, Jian-Lin
  • Hanotte, Olivier
  • Periasamy, Kathiravan
  • Johansson, Anna M.
  • Hallsson, Jón H.
  • Kantanen, Juha
  • Coltman, David W.
  • Bruford, Michael W.
  • Lenstra, Johannes A.
  • Li, Meng-Hua
The PDF file includes: Supplementary Figs. S1 to S31. -- Tables S1 to S50 in the Excel files., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311656
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311656
HANDLE: http://hdl.handle.net/10261/311656
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311656
PMID: http://hdl.handle.net/10261/311656
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311656
Ver en: http://hdl.handle.net/10261/311656
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311656

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311658
Dataset. 2022

IMAGE_5_MOLECULAR CHARACTERIZATION, TARGETING AND EXPRESSION ANALYSIS OF CHLOROPLAST AND MITOCHONDRION PROTEIN IMPORT COMPONENTS IN NICOTIANA BENTHAMIANA.TIF

  • Saiz-Bonilla, María
  • Martín Merchán, Andrea
  • Pallás, Vicente
  • Navarro, José A.
Improved bioinformatics tools for annotating gene function are becoming increasingly available, but such information must be considered theoretical until further experimental evidence proves it. In the work reported here, the genes for the main components of the translocons of the outer membrane of chloroplasts (Toc) and mitochondria (Tom), including preprotein receptors and protein-conducting channels of N. benthamiana, were identified. Sequence identity searches and phylogenetic relationships with functionally annotated sequences such as those of A. thaliana revealed that N. benthamiana orthologs mainly exist as recently duplicated loci. Only a Toc34 ortholog was found (NbToc34), while Toc159 receptor family was composed of four orthologs but somewhat different from those of A. thaliana. Except for NbToc90, the rest (NbToc120, NbToc159A and NbToc159B) had a molecular weight of about 150 kDa and an acidic domain similar in length. Only two orthologs of the Tom20 receptors, NbTom20-1 and NbTom20-2, were found. The number of the Toc and Tom receptor isoforms in N. benthamiana was comparable to that previously reported in tomato and what we found in BLAST searches in other species in the genera Nicotiana and Solanum. After cloning, the subcellular localization of N. benthamiana orthologs was studied, resulting to be identical to that of A. thaliana receptors. Phenotype analysis after silencing together with relative expression analysis in roots, stems and leaves revealed that, except for the Toc and Tom channel-forming components (NbToc75 and NbTom40) and NbToc34, functional redundancy could be observed either among Toc159 or mitochondrial receptors. Finally, heterodimer formation between NbToc34 and the NbToc159 family receptors was confirmed by two alternative techniques indicating that different Toc complexes could be assembled. Additional work needs to be addressed to know if this results in a functional specialization of each Toc complex., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311658
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311658
HANDLE: http://hdl.handle.net/10261/311658
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311658
PMID: http://hdl.handle.net/10261/311658
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311658
Ver en: http://hdl.handle.net/10261/311658
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311658

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311659
Dataset. 2022

LAYER-SPECIFIC PYRAMIDAL NEURON PROPERTIES UNDERLIE DIVERSE ANTERIOR CINGULATE CORTICAL MOTOR AND LIMBIC NETWORKS: SUPPLEMENTARY DATA

  • Medalla, Maria
  • Chang, Wayne
  • Ibáñez, Sara
  • Guillamón-Vivancos, Teresa
  • Nittmann, Mathias
  • Kapitonava, Anastasia
  • Busch, Silas E.
  • Moore, Tara L.
  • Rosene, Douglas L.
  • Luebke, Jennifer I.
Supplementary data: Table S2. Electrophysiological Properties of ACC PMd-targeting and AMY-targeting pyramidal neurons. Supplementary Figure S1. Dendritic reconstructions of tracer-labeled neurons. Representative 3D reconstructions of AMY-targeting and PMd -targeting projection neurons in layers 3 and 5. Supplementary Figure S2. Effects of firing frequency adaption to synchrony of distinct ACC networks. Supplementary Figure S3. Representative plots of simulated low and high stochastic drive (IsFigure S4. Simulated output of networks with and without inhibition and recurrent excitation to pyramidal neurons. Ctoch)., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311659
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311659
HANDLE: http://hdl.handle.net/10261/311659
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311659
PMID: http://hdl.handle.net/10261/311659
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311659
Ver en: http://hdl.handle.net/10261/311659
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311659

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311660
Dataset. 2022

IMAGE_4_MOLECULAR CHARACTERIZATION, TARGETING AND EXPRESSION ANALYSIS OF CHLOROPLAST AND MITOCHONDRION PROTEIN IMPORT COMPONENTS IN NICOTIANA BENTHAMIANA.TIF

  • Saiz-Bonilla, María
  • Martín Merchán, Andrea
  • Pallás, Vicente
  • Navarro, José A.
Improved bioinformatics tools for annotating gene function are becoming increasingly available, but such information must be considered theoretical until further experimental evidence proves it. In the work reported here, the genes for the main components of the translocons of the outer membrane of chloroplasts (Toc) and mitochondria (Tom), including preprotein receptors and protein-conducting channels of N. benthamiana, were identified. Sequence identity searches and phylogenetic relationships with functionally annotated sequences such as those of A. thaliana revealed that N. benthamiana orthologs mainly exist as recently duplicated loci. Only a Toc34 ortholog was found (NbToc34), while Toc159 receptor family was composed of four orthologs but somewhat different from those of A. thaliana. Except for NbToc90, the rest (NbToc120, NbToc159A and NbToc159B) had a molecular weight of about 150 kDa and an acidic domain similar in length. Only two orthologs of the Tom20 receptors, NbTom20-1 and NbTom20-2, were found. The number of the Toc and Tom receptor isoforms in N. benthamiana was comparable to that previously reported in tomato and what we found in BLAST searches in other species in the genera Nicotiana and Solanum. After cloning, the subcellular localization of N. benthamiana orthologs was studied, resulting to be identical to that of A. thaliana receptors. Phenotype analysis after silencing together with relative expression analysis in roots, stems and leaves revealed that, except for the Toc and Tom channel-forming components (NbToc75 and NbTom40) and NbToc34, functional redundancy could be observed either among Toc159 or mitochondrial receptors. Finally, heterodimer formation between NbToc34 and the NbToc159 family receptors was confirmed by two alternative techniques indicating that different Toc complexes could be assembled. Additional work needs to be addressed to know if this results in a functional specialization of each Toc complex., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311660
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311660
HANDLE: http://hdl.handle.net/10261/311660
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311660
PMID: http://hdl.handle.net/10261/311660
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311660
Ver en: http://hdl.handle.net/10261/311660
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311660

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311661
Dataset. 2022

IMAGE_3_MOLECULAR CHARACTERIZATION, TARGETING AND EXPRESSION ANALYSIS OF CHLOROPLAST AND MITOCHONDRION PROTEIN IMPORT COMPONENTS IN NICOTIANA BENTHAMIANA.TIF

  • Saiz-Bonilla, María
  • Martín Merchán, Andrea
  • Pallás, Vicente
  • Navarro, José A.
Improved bioinformatics tools for annotating gene function are becoming increasingly available, but such information must be considered theoretical until further experimental evidence proves it. In the work reported here, the genes for the main components of the translocons of the outer membrane of chloroplasts (Toc) and mitochondria (Tom), including preprotein receptors and protein-conducting channels of N. benthamiana, were identified. Sequence identity searches and phylogenetic relationships with functionally annotated sequences such as those of A. thaliana revealed that N. benthamiana orthologs mainly exist as recently duplicated loci. Only a Toc34 ortholog was found (NbToc34), while Toc159 receptor family was composed of four orthologs but somewhat different from those of A. thaliana. Except for NbToc90, the rest (NbToc120, NbToc159A and NbToc159B) had a molecular weight of about 150 kDa and an acidic domain similar in length. Only two orthologs of the Tom20 receptors, NbTom20-1 and NbTom20-2, were found. The number of the Toc and Tom receptor isoforms in N. benthamiana was comparable to that previously reported in tomato and what we found in BLAST searches in other species in the genera Nicotiana and Solanum. After cloning, the subcellular localization of N. benthamiana orthologs was studied, resulting to be identical to that of A. thaliana receptors. Phenotype analysis after silencing together with relative expression analysis in roots, stems and leaves revealed that, except for the Toc and Tom channel-forming components (NbToc75 and NbTom40) and NbToc34, functional redundancy could be observed either among Toc159 or mitochondrial receptors. Finally, heterodimer formation between NbToc34 and the NbToc159 family receptors was confirmed by two alternative techniques indicating that different Toc complexes could be assembled. Additional work needs to be addressed to know if this results in a functional specialization of each Toc complex., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311661
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311661
HANDLE: http://hdl.handle.net/10261/311661
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311661
PMID: http://hdl.handle.net/10261/311661
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311661
Ver en: http://hdl.handle.net/10261/311661
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311661

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311662
Dataset. 2022

IMAGE_2_MOLECULAR CHARACTERIZATION, TARGETING AND EXPRESSION ANALYSIS OF CHLOROPLAST AND MITOCHONDRION PROTEIN IMPORT COMPONENTS IN NICOTIANA BENTHAMIANA.TIF

  • Saiz-Bonilla, María
  • Martín Merchán, Andrea
  • Pallás, Vicente
  • Navarro, José A.
Improved bioinformatics tools for annotating gene function are becoming increasingly available, but such information must be considered theoretical until further experimental evidence proves it. In the work reported here, the genes for the main components of the translocons of the outer membrane of chloroplasts (Toc) and mitochondria (Tom), including preprotein receptors and protein-conducting channels of N. benthamiana, were identified. Sequence identity searches and phylogenetic relationships with functionally annotated sequences such as those of A. thaliana revealed that N. benthamiana orthologs mainly exist as recently duplicated loci. Only a Toc34 ortholog was found (NbToc34), while Toc159 receptor family was composed of four orthologs but somewhat different from those of A. thaliana. Except for NbToc90, the rest (NbToc120, NbToc159A and NbToc159B) had a molecular weight of about 150 kDa and an acidic domain similar in length. Only two orthologs of the Tom20 receptors, NbTom20-1 and NbTom20-2, were found. The number of the Toc and Tom receptor isoforms in N. benthamiana was comparable to that previously reported in tomato and what we found in BLAST searches in other species in the genera Nicotiana and Solanum. After cloning, the subcellular localization of N. benthamiana orthologs was studied, resulting to be identical to that of A. thaliana receptors. Phenotype analysis after silencing together with relative expression analysis in roots, stems and leaves revealed that, except for the Toc and Tom channel-forming components (NbToc75 and NbTom40) and NbToc34, functional redundancy could be observed either among Toc159 or mitochondrial receptors. Finally, heterodimer formation between NbToc34 and the NbToc159 family receptors was confirmed by two alternative techniques indicating that different Toc complexes could be assembled. Additional work needs to be addressed to know if this results in a functional specialization of each Toc complex., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311662
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311662
HANDLE: http://hdl.handle.net/10261/311662
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311662
PMID: http://hdl.handle.net/10261/311662
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311662
Ver en: http://hdl.handle.net/10261/311662
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311662

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311663
Dataset. 2022

SUPPORTING INFORMATION FOR SENSORIMOTOR EFFECTS OF PLASTICITY-INDUCING PERCUTANEOUS PERIPHERAL NERVE STIMULATION PROTOCOLS: A BLINDED, RANDOMIZED CLINICAL TRIAL

  • Beltrá, P.
  • Ruiz-del-Portal, I.
  • Ortega, F. J.
  • Valdesuso, R.
  • Delicado-Miralles, Miguel
  • Velasco, Enrique
Supporting Information: Figures and Tables. Supplementary Material., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311663
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311663
HANDLE: http://hdl.handle.net/10261/311663
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311663
PMID: http://hdl.handle.net/10261/311663
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311663
Ver en: http://hdl.handle.net/10261/311663
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311663

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311664
Dataset. 2022

IMAGE_1_MOLECULAR CHARACTERIZATION, TARGETING AND EXPRESSION ANALYSIS OF CHLOROPLAST AND MITOCHONDRION PROTEIN IMPORT COMPONENTS IN NICOTIANA BENTHAMIANA.TIF

  • Saiz-Bonilla, María
  • Martín Merchán, Andrea
  • Pallás, Vicente
  • Navarro, José A.
Improved bioinformatics tools for annotating gene function are becoming increasingly available, but such information must be considered theoretical until further experimental evidence proves it. In the work reported here, the genes for the main components of the translocons of the outer membrane of chloroplasts (Toc) and mitochondria (Tom), including preprotein receptors and protein-conducting channels of N. benthamiana, were identified. Sequence identity searches and phylogenetic relationships with functionally annotated sequences such as those of A. thaliana revealed that N. benthamiana orthologs mainly exist as recently duplicated loci. Only a Toc34 ortholog was found (NbToc34), while Toc159 receptor family was composed of four orthologs but somewhat different from those of A. thaliana. Except for NbToc90, the rest (NbToc120, NbToc159A and NbToc159B) had a molecular weight of about 150 kDa and an acidic domain similar in length. Only two orthologs of the Tom20 receptors, NbTom20-1 and NbTom20-2, were found. The number of the Toc and Tom receptor isoforms in N. benthamiana was comparable to that previously reported in tomato and what we found in BLAST searches in other species in the genera Nicotiana and Solanum. After cloning, the subcellular localization of N. benthamiana orthologs was studied, resulting to be identical to that of A. thaliana receptors. Phenotype analysis after silencing together with relative expression analysis in roots, stems and leaves revealed that, except for the Toc and Tom channel-forming components (NbToc75 and NbTom40) and NbToc34, functional redundancy could be observed either among Toc159 or mitochondrial receptors. Finally, heterodimer formation between NbToc34 and the NbToc159 family receptors was confirmed by two alternative techniques indicating that different Toc complexes could be assembled. Additional work needs to be addressed to know if this results in a functional specialization of each Toc complex., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311664
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311664
HANDLE: http://hdl.handle.net/10261/311664
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311664
PMID: http://hdl.handle.net/10261/311664
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311664
Ver en: http://hdl.handle.net/10261/311664
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311664

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311665
Dataset. 2022

DATASHEET_1_MOLECULAR CHARACTERIZATION, TARGETING AND EXPRESSION ANALYSIS OF CHLOROPLAST AND MITOCHONDRION PROTEIN IMPORT COMPONENTS IN NICOTIANA BENTHAMIANA.DOCX

  • Saiz-Bonilla, María
  • Martín Merchán, Andrea
  • Pallás, Vicente
  • Navarro, José A.
Improved bioinformatics tools for annotating gene function are becoming increasingly available, but such information must be considered theoretical until further experimental evidence proves it. In the work reported here, the genes for the main components of the translocons of the outer membrane of chloroplasts (Toc) and mitochondria (Tom), including preprotein receptors and protein-conducting channels of N. benthamiana, were identified. Sequence identity searches and phylogenetic relationships with functionally annotated sequences such as those of A. thaliana revealed that N. benthamiana orthologs mainly exist as recently duplicated loci. Only a Toc34 ortholog was found (NbToc34), while Toc159 receptor family was composed of four orthologs but somewhat different from those of A. thaliana. Except for NbToc90, the rest (NbToc120, NbToc159A and NbToc159B) had a molecular weight of about 150 kDa and an acidic domain similar in length. Only two orthologs of the Tom20 receptors, NbTom20-1 and NbTom20-2, were found. The number of the Toc and Tom receptor isoforms in N. benthamiana was comparable to that previously reported in tomato and what we found in BLAST searches in other species in the genera Nicotiana and Solanum. After cloning, the subcellular localization of N. benthamiana orthologs was studied, resulting to be identical to that of A. thaliana receptors. Phenotype analysis after silencing together with relative expression analysis in roots, stems and leaves revealed that, except for the Toc and Tom channel-forming components (NbToc75 and NbTom40) and NbToc34, functional redundancy could be observed either among Toc159 or mitochondrial receptors. Finally, heterodimer formation between NbToc34 and the NbToc159 family receptors was confirmed by two alternative techniques indicating that different Toc complexes could be assembled. Additional work needs to be addressed to know if this results in a functional specialization of each Toc complex., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311665
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311665
HANDLE: http://hdl.handle.net/10261/311665
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311665
PMID: http://hdl.handle.net/10261/311665
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311665
Ver en: http://hdl.handle.net/10261/311665
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311665

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311668
Dataset. 2022

GLIAL-SECRETED NETRINS REGULATE ROBO1/RAC1-CDC42 SIGNALING THRESHOLD LEVELS DURING DROSOPHILA ASYMMETRIC NEURAL STEM AND PROGENITOR CELL DIVISION [DATASET]

  • Torres Jurado, Ana de
  • Manzanero-Ortiz, Sandra
  • Carmena, Ana
Figures, original raw data, of the above paper., Peer reviewed

Proyecto: //
DOI: http://hdl.handle.net/10261/311668
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311668
HANDLE: http://hdl.handle.net/10261/311668
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311668
PMID: http://hdl.handle.net/10261/311668
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311668
Ver en: http://hdl.handle.net/10261/311668
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/311668

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