Dataset.

Additional file 1 of Altered methylation pattern in EXOC4 is associated with stroke outcome: an epigenome-wide association study

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331080
Digital.CSIC. Repositorio Institucional del CSIC
  • Cullell, Nàtalia
  • Soriano-Tárraga, Carolina
  • Gallego-Fabrega, Cristina
  • Cárcel-Márquez, Jara
  • Muiño, Elena
  • Llucià-Carol, Laia
  • Lledós, Miquel
  • Esteller, Manel
  • Moura, Manuel Castro de
  • Montaner, Joan
  • Rosell, Anna
  • Delgado, Pilar
  • Marti-Fabregas, Joan
  • Krupinski, Jerzy
  • Roquer, Jaume
  • Jiménez-Conde, Jordi
  • Fernández-Cadenas, Israel
1-Supplemental Materials and Methods. 2- Supplemental e-FIGURES. Figure I: Workflow for CpG-sites and sample QCs. Figure II: Batch effect evaluation with MDS and SVD plots. Figure III: Manhattan plots for DMCT. Figure IV: cg00039070 methylation correlation between blood and brain. Figure V: Blood–Brain Epigenetic Concordance (BECon) results for cg00039070. 3- Supplemental e-TABLES. Table I: Analysis of variables associated with ∆NIHSS in bivariate and regression analysis. Table II: Analysis of variables associated with mRS at 3 months in bivariate and regression analysis. Table III: Summary statistics for the discovery EWAS adjusted by batch. Table IV: Feature enrichment analysis. Table V: Differentially methylated region (DMR) results. Table VI: Differentially methylated block (DMB) results. Table VII: EWAS summary statistics in the meta-analyses for dichotomic ∆NIHSS. Table VIII: Demographic and clinical data for the subjects included in the analysis with SOMAscan. Table IX: eFORGE analysis. 4- Supplemental References., Boehringer Ingelheim España Instituto de Salud Carlos III Agència de Gestió d'Ajuts Universitaris i de Recerca FUNDACIÓ DOCÈNCIA I RECERCA MÚTUATERRASSA Bristol-Myers Squibb Eranet-Neuron Fundació la Marató de TV3., Peer reviewed
 
DOI: http://hdl.handle.net/10261/331080
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331080

HANDLE: http://hdl.handle.net/10261/331080
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331080
 
Ver en: http://hdl.handle.net/10261/331080
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331080

Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/331080
Dataset. 2022

ADDITIONAL FILE 1 OF ALTERED METHYLATION PATTERN IN EXOC4 IS ASSOCIATED WITH STROKE OUTCOME: AN EPIGENOME-WIDE ASSOCIATION STUDY

Digital.CSIC. Repositorio Institucional del CSIC
  • Cullell, Nàtalia
  • Soriano-Tárraga, Carolina
  • Gallego-Fabrega, Cristina
  • Cárcel-Márquez, Jara
  • Muiño, Elena
  • Llucià-Carol, Laia
  • Lledós, Miquel
  • Esteller, Manel
  • Moura, Manuel Castro de
  • Montaner, Joan
  • Rosell, Anna
  • Delgado, Pilar
  • Marti-Fabregas, Joan
  • Krupinski, Jerzy
  • Roquer, Jaume
  • Jiménez-Conde, Jordi
  • Fernández-Cadenas, Israel
1-Supplemental Materials and Methods. 2- Supplemental e-FIGURES. Figure I: Workflow for CpG-sites and sample QCs. Figure II: Batch effect evaluation with MDS and SVD plots. Figure III: Manhattan plots for DMCT. Figure IV: cg00039070 methylation correlation between blood and brain. Figure V: Blood–Brain Epigenetic Concordance (BECon) results for cg00039070. 3- Supplemental e-TABLES. Table I: Analysis of variables associated with ∆NIHSS in bivariate and regression analysis. Table II: Analysis of variables associated with mRS at 3 months in bivariate and regression analysis. Table III: Summary statistics for the discovery EWAS adjusted by batch. Table IV: Feature enrichment analysis. Table V: Differentially methylated region (DMR) results. Table VI: Differentially methylated block (DMB) results. Table VII: EWAS summary statistics in the meta-analyses for dichotomic ∆NIHSS. Table VIII: Demographic and clinical data for the subjects included in the analysis with SOMAscan. Table IX: eFORGE analysis. 4- Supplemental References., Boehringer Ingelheim España Instituto de Salud Carlos III Agència de Gestió d'Ajuts Universitaris i de Recerca FUNDACIÓ DOCÈNCIA I RECERCA MÚTUATERRASSA Bristol-Myers Squibb Eranet-Neuron Fundació la Marató de TV3., Peer reviewed




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