BUSCADOR RECOLECTA

Digital.CSIC. Repositorio Institucional del CSIC

oai:digital.csic.es:10261/331452

20 pages. -- Figure S1. Bifunctional lipid probes and workflow used for in vivo photoaffinity binding studies. -- Figure S2. Photolabeling experiments of non-lipid nanodomain marker (transferrin receptor) and lipid nanodomain marker (Cav-1) with bifunctional lipids and competition experiments between bifunctional analogues and cold lipids in living cells. -- Figure S3. Role of previously described chol-binding motif in IFN-γR2-chol interaction in vivo. -- Figure S4. Physiochemical analysis of IFN-γR2TMD wild type and mutants. -- Figure S5. Validation of the novel chol-binding domain localized within the IFN-γR2TMD. -- Figure S6. Characterization of IFN-γR1 and IFN-γR2 constructs for ID-PRIME and proof of principle. -- Figure S7. Chol binding is required for IFN-γR transmembrane signal activation and PDL1 cell surface exposure in response to IFN-γ stimulation. -- Figure S8. Subcellular localization of candidate chol-binding proteins. -- Supplementary Table 1. Single-and Multi-span motifs found using MOPRO. -- Supplementary Table 2. List of chol-binding protein candidates., Peer reviewed