Dataset.
Supplemental information for GluN3A excitatory glycine receptors control adult cortical and amygdalar circuits
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/313133
Digital.CSIC. Repositorio Institucional del CSIC
- Bossi, Simon
- Dhanasobhon, Dhanasak
- Ellis-Davies, Graham C.R.
- Frontera, Jimena
- Brito Van Velze, Marcel de
- Lourenço, Joana
- Murillo, Alvaro
- Luján, Rafael
- Casado, Mariano
- Pérez-Otaño, Isabel
- Bacci, Alberto
- Popa, Daniela
- Paolitti, Pierre
- Rebola, Nelson
Figure S1: Grin3a mRNA is abundantly expressed in vGlut2-positive neurons in the BLA and glycine-evoked currents display current-voltage relationship compatible with the activation of non-selective cationic channels. Related to Figures 1 and 2.
Figure S2: Photolysis of CNI-Gly reliably activates inhibitory glycine receptors in dorsal horn spinal cord neurons and induces inward currents in SST-INs. Related to Figure 3.
Figure S3: Photolysis of MNI-glutamate shows enrichment of ionotropic glutamatergic receptors in spines of BLA PNs. Related to Figure 3.
Figure S4: Tonic activation and modulation of eGlyR in BLA neuronal populations. Related to Figure 4.
Figure S5: Modulation of eGlyR activity in S1 SST-INs. Related to Figure 5.
Figure S6: shGluN3A constructs effectively reduce functional expression of eGlyRs in SST-INs and BLA PNs. Related to Figure 6.
Figure S7: Dopamine modulation of eGlyR activity; evaluation of cell types infected by AAV-shGluN3A constructs in the BLA and assessment of locomotion and anxiety-like behavior in shRNA treated mice. Related to Figure 7.
Table S1: Passive and firing properties of S1 SST-INs in WT and GluN3A KO mice. Related to Figure5., Peer reviewed
DOI: http://hdl.handle.net/10261/313133
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/313133
HANDLE: http://hdl.handle.net/10261/313133
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/313133
Ver en: http://hdl.handle.net/10261/313133
Digital.CSIC. Repositorio Institucional del CSIC
oai:digital.csic.es:10261/313133
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